Transcriptional profiling of circulating tumor cells in multiple myeloma: a new model to understand disease dissemination

Evolving imprinting control regions: KRAB zinc fingers hold the key

(2019) Aimee M. Juan et al.   GENES & DEVELOPMENT

Circulating Plasma Cells at the Time of Collection of Autologous PBSC for Transplant in Multiple Myeloma Patients is a Negative Prognostic Factor Even in the Age of Post-Transplant Maintenance Therapy

(2018) Andrew J. Cowan et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

CD44 is a RAS/STAT5-regulated invasion receptor that triggers disease expansion in advanced mastocytosis

(2018) Niklas Mueller et al.   BLOOD

Platelets Enhance Multiple Myeloma Progression via IL-1β Upregulation

(2018) Satoshi Takagi et al.   CLINICAL CANCER RESEARCH

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Flow cytometry for fast screening and automated risk assessment in systemic light-chain amyloidosis

(2018) Noemi Puig et al.   LEUKEMIA

The emerging link between cancer, metabolism, and circadian rhythms

(2018) Selma Masri et al.   NATURE MEDICINE

Single cell dissection of plasma cell heterogeneity in symptomatic and asymptomatic myeloma

(2018) Guy Ledergor et al.   NATURE MEDICINE

New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer

(2018) Anushka Dongre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Next generation flow for minimally-invasive blood characterization of MGUS and multiple myeloma at diagnosis based on circulating tumor plasma cells (CTPC)

(2018) L. Sanoja-Flores et al.   Blood Cancer Journal

Serial measurements of circulating plasma cells before and after induction therapy have an independent prognostic impact in patients with multiple myeloma undergoing upfront autologous transplantation

(2017) Rajshekhar Chakraborty et al.   HAEMATOLOGICA

Prognostic impact of circulating plasma cells in patients with multiple myeloma: implications for plasma cell leukemia definition

(2017) Miquel Granell et al.   HAEMATOLOGICA

Role of Galectins in Multiple Myeloma

(2017) Paola Storti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

E-selectin ligands recognised by HECA452 induce drug resistance in myeloma, which is overcome by the E-selectin antagonist, GMI-1271

(2017) A Natoni et al.   LEUKEMIA

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix

(2017) S V Glavey et al.   LEUKEMIA

Next Generation Flow for highly sensitive and standardized detection of minimal residual disease in multiple myeloma

(2017) J Flores-Montero et al.   LEUKEMIA

Cancer stem cells revisited

(2017) Eduard Batlle et al.   NATURE MEDICINE

The Mutational Landscape of Circulating Tumor Cells in Multiple Myeloma

(2017) Yuji Mishima et al.   Cell Reports

Serial measurements of circulating plasma cells before and after induction therapy have an independent prognostic impact in patients with multiple myeloma undergoing upfront autologous transplantation

(2017) Rajshekhar Chakraborty et al.   HAEMATOLOGICA

Prognostic impact of circulating plasma cells in patients with multiple myeloma: implications for plasma cell leukemia definition

(2017) Miquel Granell et al.   HAEMATOLOGICA

The integrated pathway of TGFβ/Snail with TNFα/NFκB may facilitate the tumor-stroma interaction in the EMT process and colorectal cancer prognosis

(2017) Hui Li et al.   Scientific Reports

Metastasis: new functional implications of platelets and megakaryocytes

(2016) Raphael Leblanc et al.   BLOOD

Phenotypic and genomic analysis of multiple myeloma minimal residual disease tumor cells: a new model to understand chemoresistance

(2016) B. Paiva et al.   BLOOD

Prognostic impact of CD44-positive cancer stem-like cells at the invasive front of gastric cancer

(2016) Hirokazu Kodama et al.   BRITISH JOURNAL OF CANCER

SMYD3 stimulates EZR and LOXL2 transcription to enhance proliferation, migration, and invasion in esophageal squamous cell carcinoma

(2016) Ying Zhu et al.   HUMAN PATHOLOGY

Targeting Intrinsic and Extrinsic Vulnerabilities for the Treatment of Multiple Myeloma

(2016) Nagaraju Anreddy et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo

(2016) P Storti et al.   LEUKEMIA

Quantification of circulating clonal plasma cells via multiparametric flow cytometry identifies patients with smoldering multiple myeloma at high risk of progression

(2016) W I Gonsalves et al.   LEUKEMIA

IQGAP1 Scaffold-MAP Kinase Interactions Enhance Multiple Myeloma Clonogenic Growth and Self-Renewal

(2016) C. B. Gocke et al.   MOLECULAR CANCER THERAPEUTICS

High expression of CDC6 is associated with accelerated cell proliferation and poor prognosis of epithelial ovarian cancer

(2016) Yan Deng et al.   PATHOLOGY RESEARCH AND PRACTICE

Genetic interrogation of circulating multiple myeloma cells at single-cell resolution

(2016) J. G. Lohr et al.   Science Translational Medicine

Cholesterol lowering: role in cancer prevention and treatment

(2015) Toshiyuki Murai   BIOLOGICAL CHEMISTRY

Galectin-1 Controls the Proliferation and Migration of Liver Sinusoidal Endothelial Cells and Their Interaction With Hepatocarcinoma Cells

(2015) Malena Manzi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Revised International Staging System for Multiple Myeloma: A Report From International Myeloma Working Group

(2015) Antonio Palumbo et al.   JOURNAL OF CLINICAL ONCOLOGY

CFAP54 is required for proper ciliary motility and assembly of the central pair apparatus in mice

(2015) Casey W. McKenzie et al.   MOLECULAR BIOLOGY OF THE CELL

Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow

(2015) Andreas Schlitzer et al.   NATURE IMMUNOLOGY

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation

(2015) Aldo M. Roccaro et al.   Cell Reports

Concise Review: Emerging Role of CD44 in Cancer Stem Cells: A Promising Biomarker and Therapeutic Target

(2015) Yongmin Yan et al.   Stem Cells Translational Medicine

Common Polymorphisms in the NFKBIA Gene and Cancer Susceptibility: A Meta-Analysis

(2015) Meng Zhang et al.   MEDICAL SCIENCE MONITOR

Key Roles of Hyaluronan and Its CD44 Receptor in the Stemness and Survival of Cancer Stem Cells

(2015) Theerawut Chanmee et al.   Frontiers in Oncology

Frequent Down Regulation of the Tumor Suppressor Gene A20 in Multiple Myeloma

(2015) Katharina Troppan et al.   PLoS One

Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity

(2015) Lavinia Raimondi et al.   Oncotarget

Digital Encoding of Cellular mRNAs Enabling Precise and Absolute Gene Expression Measurement by Single-Molecule Counting

(2014) Glenn K. Fu et al.   ANALYTICAL CHEMISTRY

Quantification of clonal circulating plasma cells in relapsed multiple myeloma

(2014) Wilson I. Gonsalves et al.   BRITISH JOURNAL OF HAEMATOLOGY

AHNAK: The giant jack of all trades

(2014) T.A. Davis et al.   CELLULAR SIGNALLING

International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma

(2014) S Vincent Rajkumar et al.   LANCET ONCOLOGY

Quantification of clonal circulating plasma cells in newly diagnosed multiple myeloma: implications for redefining high-risk myeloma

(2014) W I Gonsalves et al.   LEUKEMIA

Cholesterol and Cancer, in the Balance

(2014) S. Silvente-Poirot et al.   SCIENCE

Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

(2014) D. A. Jaitin et al.   SCIENCE

Higher bone marrow LGALS3 expression is an independent unfavorable prognostic factor for overall survival in patients with acute myeloid leukemia

(2013) C.-L. Cheng et al.   BLOOD

Detailed characterization of multiple myeloma circulating tumor cells shows unique phenotypic, cytogenetic, functional, and circadian distribution profile

(2013) B. Paiva et al.   BLOOD

Circulating clonotypic B cells in multiple myeloma and monoclonal gammopathy of undetermined significance

(2013) L. S. Thiago et al.   HAEMATOLOGICA

The proliferation arrest of primary tumor cells out-of-niche is associated with widespread downregulation of mitotic and transcriptional genes

(2013) Yossi Cohen et al.   Hematology

Evidence of a role for CD44 and cell adhesion in mediating resistance to lenalidomide in multiple myeloma: therapeutic implications

(2013) C C Bjorklund et al.   LEUKEMIA

IQGAP1 plays an important role in the cell proliferation of multiple myeloma via the MAP kinase (ERK) pathway

(2013) YONGYONG MA et al.   ONCOLOGY REPORTS

AHNAK and Inflammatory Markers Predict Poor Survival in Laryngeal Carcinoma

(2013) Claudia A. Dumitru et al.   PLoS One

NPP4 is a procoagulant enzyme on the surface of vascular endothelium

(2012) R. A. Albright et al.   BLOOD

Myeloma as a model for the process of metastasis: implications for therapy

(2012) I. M. Ghobrial   BLOOD

High levels of peripheral blood circulating plasma cells as a specific risk factor for progression of smoldering multiple myeloma

(2012) G Bianchi et al.   LEUKEMIA

Interferon-inducible guanylate binding protein (GBP2) is associated with better prognosis in breast cancer and indicates an efficient T cell response

(2012) Patricio Godoy et al.   Breast Cancer

Hyaluronan-CD44 interactions as potential targets for cancer therapy

(2011) Suniti Misra et al.   FEBS Journal

Competition between clonal plasma cells and normal cells for potentially overlapping bone marrow niches is associated with a progressively altered cellular distribution in MGUS vs myeloma

(2011) B Paiva et al.   LEUKEMIA

Multiple Myeloma

(2011) Antonio Palumbo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Haematopoietic stem cell release is regulated by circadian oscillations

(2008) Simón Méndez-Ferrer et al.   NATURE