Cirrhotic Human Liver Extracellular Matrix 3D Scaffolds Promote Smad-Dependent TGF-β1 Epithelial Mesenchymal Transition

Novel Transforming Growth Factor Beta Receptor I Kinase Inhibitor Galunisertib ( LY 2157299) in Advanced Hepatocellular Carcinoma

(2019) Sandrine Faivre et al.   LIVER INTERNATIONAL

A Phase 2 Study of Galunisertib (TGF-β1 Receptor Type I Inhibitor) and Sorafenib in Patients With Advanced Hepatocellular Carcinoma

(2019) R.K. Kelley et al.   Clinical and Translational Gastroenterology

The adenosine monophosphate-activated protein kinase-vacuolar adenosine triphosphatase-pH axis: A key regulator of the profibrogenic phenotype of human hepatic stellate cells

(2018) Giusi Marrone et al.   HEPATOLOGY

The role of molecular enrichment on future therapies in hepatocellular carcinoma

(2018) Jean-Charles Nault et al.   JOURNAL OF HEPATOLOGY

Animal models for hepatocellular carcinoma

(2018) Hui Emma Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

TGF-β as Multifaceted Orchestrator in HCC Progression: Signaling, EMT, Immune Microenvironment, and Novel Therapeutic Perspectives

(2018) Serena Mancarella et al.   SEMINARS IN LIVER DISEASE

Reactive gamma-ketoaldehydes as novel activators of hepatic stellate cells in vitro

(2017) Lisa Longato et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fibronectin fibrils regulate TGF-β1-induced Epithelial-Mesenchymal Transition

(2017) Lauren A. Griggs et al.   MATRIX BIOLOGY

Transforming Growth Factor-β Receptors and Smads: Regulatory Complexity and Functional Versatility

(2017) Erine H. Budi et al.   TRENDS IN CELL BIOLOGY

Serum fibronectin distinguishes the early stages of hepatocellular carcinoma

(2017) Hyunsoo Kim et al.   Scientific Reports

Rapid production of human liver scaffolds for functional tissue engineering by high shear stress oscillation-decellularization

(2017) Giuseppe Mazza et al.   Scientific Reports

Quantification of fibronectin as a method to assess ex vivo extracellular matrix remodeling

(2016) C.L. Bager et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proteomic analysis of naturally-sourced biological scaffolds

(2016) Qiyao Li et al.   BIOMATERIALS

Alternative Animal and Non-Animal Models for Drug Discovery and Development: Bonus or Burden?

(2016) Irlan Almeida Freires et al.   PHARMACEUTICAL RESEARCH

Hepatocellular carcinoma

(2016) Josep M. Llovet et al.   Nature Reviews Disease Primers

Novel insights into the function and dynamics of extracellular matrix in liver fibrosis

(2015) Morten A. Karsdal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Structural and functional hepatocyte polarity and liver disease

(2015) Paul Gissen et al.   JOURNAL OF HEPATOLOGY

Decellularized human liver as a natural 3D-scaffold for liver bioengineering and transplantation

(2015) Giuseppe Mazza et al.   Scientific Reports

Moving towards personalised therapy in patients with hepatocellular carcinoma: the role of the microenvironment

(2014) Gianluigi Giannelli et al.   GUT

Hepatocellular carcinoma: clinical frontiers and perspectives

(2014) Jordi Bruix et al.   GUT

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Hepatic stellate cells and extracellular matrix in hepatocellular carcinoma: more complicated than ever

(2014) Vinicio Carloni et al.   LIVER INTERNATIONAL

Perfusion-decellularized pancreas as a natural 3D scaffold for pancreatic tissue and whole organ engineering

(2013) Saik-Kia Goh et al.   BIOMATERIALS

Role of the Microenvironment in the Pathogenesis and Treatment of Hepatocellular Carcinoma

(2013) Virginia Hernandez–Gea et al.   GASTROENTEROLOGY

Of plasticity and specificity: dialectics of the microenvironment and macroenvironment and the organ phenotype

(2013) Ramray Bhat et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Fibrosis-dependent mechanisms of hepatocarcinogenesis

(2012) David Y. Zhang et al.   HEPATOLOGY

An overview of tissue and whole organ decellularization processes

(2011) Peter M. Crapo et al.   BIOMATERIALS

Overview of the Matrisome--An Inventory of Extracellular Matrix Constituents and Functions

(2011) R. O. Hynes et al.   Cold Spring Harbor Perspectives in Biology

A Stiff Blow from the Stroma: Collagen Crosslinking Drives Tumor Progression

(2009) Mei Rosa Ng et al.   CANCER CELL

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Non-Smad pathways in TGF-β signaling

(2008) Ying E Zhang   CELL RESEARCH

Computer-assisted image analysis of liver collagen: Relationship to Ishak scoring and hepatic venous pressure gradient

(2008) Vincenza Calvaruso et al.   HEPATOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Experimental use of nonhuman primates is not a simple problem

(2008) Niall Shanks et al.   NATURE MEDICINE

Sorafenib in Advanced Hepatocellular Carcinoma

(2008) Josep M. Llovet et al.   NEW ENGLAND JOURNAL OF MEDICINE