Emerging Autophagy Functions Shape the Tumor Microenvironment and Play a Role in Cancer Progression - Implications for Cancer Therapy
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Emerging Autophagy Functions Shape the Tumor Microenvironment and Play a Role in Cancer Progression - Implications for Cancer Therapy
Authors
Keywords
-
Journal
Frontiers in Oncology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-11-25
DOI
10.3389/fonc.2020.606436
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Therapy-Induced Senescence Drives Bone Loss
- (2020) Zhangting Yao et al. CANCER RESEARCH
- L(C3)icensing of exosomes for RNA export
- (2020) Janusz Rak NATURE CELL BIOLOGY
- Toll-Like Receptors in Natural Killer Cells and Their Application for Immunotherapy
- (2020) Ji-Yoon Noh et al. Journal of Immunology Research
- Inhibiting Forkhead box K1 induces autophagy to reverse epithelial-mesenchymal transition and metastasis in gastric cancer by regulating Myc-associated zinc finger protein in an acidic microenvironment
- (2020) Yixuan Wang et al. Aging-US
- Selective autophagy of MHC-I promotes immune evasion of pancreatic cancer
- (2020) Keisuke Yamamoto et al. Autophagy
- Autophagy regulation as a promising approach for improving cancer immunotherapy
- (2020) Nestor Ishimwe et al. CANCER LETTERS
- Autophagy inhibition potentiates the anti-EMT effects of alteronol through TGF-β/Smad3 signaling in melanoma cells
- (2020) Yong Bao et al. Cell Death & Disease
- Targeting Autophagy in Innate Immune Cells: Angel or Demon During Infection and Vaccination?
- (2020) Sha Tao et al. Frontiers in Immunology
- Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti–PD-1/PD-L1 immunotherapy
- (2020) Muhammad Zaeem Noman et al. Science Advances
- p62 is Negatively Implicated in the TRAF6-BECN1 Signaling Axis for Autophagy Activation and Cancer Progression by Toll-Like Receptor 4 (TLR4)
- (2020) Mi-Jeong Kim et al. Cells
- Targeting Autophagy Facilitates T Lymphocyte Migration by Inducing the Expression of CXCL10 in Gastric Cancer Cell Lines
- (2020) Qingyuan Meng et al. Frontiers in Oncology
- The Roles of Autophagy and Senescence in the Tumor Cell Response to Radiation
- (2020) Nipa H. Patel et al. RADIATION RESEARCH
- Regulation of Autophagy Progress via Lysosomal Depletion by Fluvastatin Nanoparticle Treatment in Breast Cancer Cells
- (2020) Hanan Elimam et al. ACS Omega
- TLR2 favors OVA-induced allergic airway inflammation in mice through JNK signaling pathway with activation of autophagy
- (2020) Lei Fang et al. LIFE SCIENCES
- Biological Functions of Autophagy Genes: A Disease Perspective
- (2019) Beth Levine et al. CELL
- Endogenous production of IL-1B by breast cancer cells drives metastasis and colonisation of the bone microenvironment.
- (2019) Claudia Tulotta et al. CLINICAL CANCER RESEARCH
- Autophagy proteins influence endocytosis for MHC restricted antigen presentation
- (2019) Christian Münz SEMINARS IN CANCER BIOLOGY
- Cyclin G1 and TASCC regulate kidney epithelial cell G2-M arrest and fibrotic maladaptive repair
- (2019) Guillaume Canaud et al. Science Translational Medicine
- The relationship between autophagy and the immune system and its applications for tumor immunotherapy
- (2019) Guan-Min Jiang et al. Molecular Cancer
- LC3-associated phagocytosis at a glance
- (2019) Bradlee L. Heckmann et al. JOURNAL OF CELL SCIENCE
- Proteome profiling of triple negative breast cancer cells overexpressing NOD1 and NOD2 receptors unveils molecular signatures of malignant cell proliferation
- (2019) Fernando J. Velloso et al. BMC GENOMICS
- Cancer-associated fibroblasts induce epithelial–mesenchymal transition of bladder cancer cells through paracrine IL-6 signalling
- (2019) Cassandra Ringuette Goulet et al. BMC CANCER
- NOD-like receptors: major players (and targets) in the interface between innate immunity and cancer
- (2019) Fernando J Velloso et al. BIOSCIENCE REPORTS
- Autophagy-Dependent Secretion: Mechanism, Factors Secreted, and Disease Implications
- (2019) Jacob New et al. Autophagy
- Crosstalk between autophagy and epithelial-mesenchymal transition and its application in cancer therapy
- (2019) Hong-Tao Chen et al. Molecular Cancer
- Autophagy-induced senescence is regulated by p38α signaling
- (2019) Konstantin Slobodnyuk et al. Cell Death & Disease
- Autophagy-Independent Functions of the Autophagy Machinery
- (2019) Lorenzo Galluzzi et al. CELL
- Autophagy as a molecular target for cancer treatment
- (2019) Nur Mehpare Kocaturk et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Deciphering the mechanism for induction of senescence-associated secretory phenotype (SASP) and its role in ageing and cancer development
- (2019) Naoko Ohtani JOURNAL OF BIOCHEMISTRY
- Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance
- (2019) Shun Li et al. Nature Communications
- Targeting Autophagy in Cancer: Recent Advances and Future Directions
- (2019) Ravi K. Amaravadi et al. Cancer Discovery
- Cudraxanthone D Regulates Epithelial-Mesenchymal Transition by Autophagy Inhibition in Oral Squamous Cell Carcinoma Cell Lines
- (2019) Su-Bin Yu et al. Evidence-based Complementary and Alternative Medicine
- Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression
- (2019) Alyssa La Belle Flynn et al. Nature Communications
- Specific autophagy and ESCRT components participate in the unconventional secretion of CFTR
- (2018) Shin Hye Noh et al. Autophagy
- Autophagy modulates transforming growth factor beta 1 induced epithelial to mesenchymal transition in non-small cell lung cancer cells
- (2018) Javad Alizadeh et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Comprehensive anti-tumor effect of Brusatol through inhibition of cell viability and promotion of apoptosis caused by autophagy via the PI3K/Akt/mTOR pathway in hepatocellular carcinoma
- (2018) Ruifan Ye et al. BIOMEDICINE & PHARMACOTHERAPY
- Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade
- (2018) Sachet A. Shukla et al. CELL
- Coroglaucigenin induces senescence and autophagy in colorectal cancer cells
- (2018) Yong-Hao Huang et al. CELL PROLIFERATION
- Autophagy in dendritic cells
- (2018) Ghita Ghislat et al. Cellular & Molecular Immunology
- The drug combination of SB202190 and SP600125 significantly inhibit the growth and metastasis of olaparib-resistant ovarian cancer cell
- (2018) Xinyan Chen et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Functions of autophagy in the tumor microenvironment and cancer metastasis
- (2018) Erin E. Mowers et al. FEBS Journal
- Knockdown of Beclin-1 impairs epithelial-mesenchymal transition of colon cancer cells
- (2018) Hong Shen et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- DRAM1 regulates the migration and invasion of hepatoblastoma cells via autophagy‑EMT pathway
- (2018) Chao Chen et al. Oncology Letters
- Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence
- (2018) Laura Vera-Ramirez et al. Nature Communications
- Autophagy-deficient breast cancer shows early tumor recurrence and escape from dormancy
- (2018) Hussein F. Aqbi et al. Oncotarget
- TGF-β2-induced EMT is dampened by inhibition of autophagy and TNF-α treatment
- (2018) Subhra Dash et al. Oncotarget
- CD4 T cell autophagy is integral to memory maintenance
- (2018) Diane Murera et al. Scientific Reports
- Non-Cell Autonomous Effects of the Senescence-Associated Secretory Phenotype in Cancer Therapy
- (2018) Tareq Saleh et al. Frontiers in Oncology
- Interleukin-1 Beta—A Friend or Foe in Malignancies?
- (2018) Rebekka Bent et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The interplay between exosomes and autophagy – partners in crime
- (2018) Jing Xu et al. JOURNAL OF CELL SCIENCE
- Autophagy induces transforming growth factor-β-dependent epithelial-mesenchymal transition in hepatocarcinoma cells through cAMP response element binding signalling
- (2018) Shaobo Hu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- ATP in the tumour microenvironment drives expression of nfP2X7, a key mediator of cancer cell survival
- (2018) SM Gilbert et al. ONCOGENE
- Targeting Toll-Like Receptors for Cancer Therapy
- (2018) Marc J. Braunstein et al. Targeted Oncology
- Tumor cell escape from therapy-induced senescence
- (2018) Tareq Saleh et al. BIOCHEMICAL PHARMACOLOGY
- The role of the unfolded protein response in cancer progression: From oncogenesis to chemoresistance
- (2018) Emma Madden et al. BIOLOGY OF THE CELL
- Targeting mTOR in Glioblastoma: Rationale and Preclinical/Clinical Evidence
- (2018) Carmen Mecca et al. DISEASE MARKERS
- Autophagy and Its Role in Protein Secretion: Implications for Cancer Therapy
- (2018) Israel Cotzomi-Ortega et al. MEDIATORS OF INFLAMMATION
- Modulating T Cell Responses via Autophagy: The Intrinsic Influence Controlling the Function of Both Antigen-Presenting Cells and T Cells
- (2018) Seth D. Merkley et al. Frontiers in Immunology
- Interleukin 6 protects pancreatic β cells from apoptosis by stimulation of autophagy
- (2017) Amelia K. Linnemann et al. FASEB JOURNAL
- Molecular Interactions of Autophagy with the Immune System and Cancer
- (2017) Yunho Jin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Beyond self-eating: The control of nonautophagic functions and signaling pathways by autophagy-related proteins
- (2017) Ken Cadwell et al. JOURNAL OF CELL BIOLOGY
- TGF-β2 initiates autophagy via Smad and non-Smad pathway to promote glioma cells’ invasion
- (2017) Chao Zhang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- High-mobility group box 1 released by autophagic cancer-associated fibroblasts maintains the stemness of luminal breast cancer cells
- (2017) Xi-Long Zhao et al. JOURNAL OF PATHOLOGY
- The role of autophagy in the cross-talk between epithelial-mesenchymal transitioned tumor cells and cancer stem-like cells
- (2017) Fabrizio Marcucci et al. Molecular Cancer
- Small-Molecule Sigma1 Modulator Induces Autophagic Degradation of PD-L1
- (2017) Christina M. Maher et al. MOLECULAR CANCER RESEARCH
- TLR2 mediates autophagy through ERK signaling pathway in Mycoplasma gallisepticum -infected RAW264.7 cells
- (2017) Ziyin Lu et al. MOLECULAR IMMUNOLOGY
- IL-12 induces autophagy in human breast cancer cells through AMPK and the PI3K/Akt pathway
- (2017) Yan Lin et al. Molecular Medicine Reports
- TGF‑β signaling: A complex role in tumorigenesis (Review)
- (2017) Shuang Liu et al. Molecular Medicine Reports
- Senescence-associated reprogramming promotes cancer stemness
- (2017) Maja Milanovic et al. NATURE
- Dual role of autophagy in hallmarks of cancer
- (2017) Shikha Satendra Singh et al. ONCOGENE
- Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner
- (2017) Takouhie Mgrditchian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Understanding the role of PD-L1/PD1 pathway blockade and autophagy in cancer therapy
- (2017) Marianela Robainas et al. OncoTargets and Therapy
- Autophagy inhibition impairs the epithelial-mesenchymal transition and enhances cisplatin sensitivity in nasopharyngeal carcinoma
- (2017) Zhongwu Su et al. Oncology Letters
- Senescent tumor cells lead the collective invasion in thyroid cancer
- (2017) Young Hwa Kim et al. Nature Communications
- Exophagy of annexin A2 via RAB11, RAB8A and RAB27A in IFN-γ-stimulated lung epithelial cells
- (2017) Ying-Da Chen et al. Scientific Reports
- Suppression of autophagy impedes glioblastoma development and induces senescence
- (2016) Noor Gammoh et al. Autophagy
- Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression
- (2016) Tobias Eggert et al. CANCER CELL
- Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma
- (2016) Curtis A. Clark et al. CANCER RESEARCH
- Autophagy, Inflammation, and Immunity: A Troika Governing Cancer and Its Treatment
- (2016) Zhenyu Zhong et al. CELL
- Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy
- (2016) Tomonori Kimura et al. EMBO JOURNAL
- Key roles of autophagy in regulating T-cell function
- (2016) Yair Botbol et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis
- (2016) Jun Wei et al. NATURE IMMUNOLOGY
- Cadherin-6 promotes EMT and cancer metastasis by restraining autophagy
- (2016) M Gugnoni et al. ONCOGENE
- Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis
- (2016) Megan K. Ruhland et al. Nature Communications
- Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse
- (2016) Marco Demaria et al. Cancer Discovery
- Activation of hERG3 channel stimulates autophagy and promotes cellular senescence in melanoma
- (2016) Mathew Perez-Neut et al. Oncotarget
- Autophagy-associated immune responses and cancer immunotherapy
- (2016) Hongming Pan et al. Oncotarget
- Induction of epithelial-mesenchymal transition (EMT) by Beclin 1 knockdown via posttranscriptional upregulation of ZEB1 in thyroid cancer cells
- (2016) Si Li et al. Oncotarget
- IDO1 involvement in mTOR pathway: a molecular mechanism of resistance to mTOR targeting in medulloblastoma
- (2016) Valentina Folgiero et al. Oncotarget
- Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1α via the PI3K/AKT/mTOR pathway
- (2016) Haiyong Wang et al. Oncotarget
- Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-to-mesenchymal transition
- (2016) Ramadevi Subramani et al. Scientific Reports
- Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization
- (2015) Kun Liu et al. Autophagy
- Autophagy is dispensable for B-cell development but essential for humoral autoimmune responses
- (2015) J Arnold et al. CELL DEATH AND DIFFERENTIATION
- Secretory autophagy
- (2015) Marisa Ponpuak et al. CURRENT OPINION IN CELL BIOLOGY
- BNIP3- and BNIP3L-Mediated Mitophagy Promotes the Generation of Natural Killer Cell Memory
- (2015) Timothy E. O’Sullivan et al. IMMUNITY
- IL-10 restricts dendritic cell (DC) growth at the monocyte-to-monocyte-derived DC interface by disrupting anti-apoptotic and cytoprotective autophagic molecular machinery
- (2015) Carla Martin et al. IMMUNOLOGIC RESEARCH
- Danusertib Induces Apoptosis, Cell Cycle Arrest, and Autophagy but Inhibits Epithelial to Mesenchymal Transition Involving PI3K/Akt/mTOR Signaling Pathway in Human Ovarian Cancer Cells
- (2015) Dan Zi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells
- (2015) Bao-Jun Ren et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Therapeutic antitumor efficacy of tumor-derived autophagosome (DRibble) vaccine on head and neck cancer
- (2015) Yongbin Mou et al. International Journal of Nanomedicine
- Inhibition of autophagy by 3-MA enhances IL-24-induced apoptosis in human oral squamous cell carcinoma cells
- (2015) Jichen Li et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Invariant NKT Cells Require Autophagy To Coordinate Proliferation and Survival Signals during Differentiation
- (2015) Bo Pei et al. JOURNAL OF IMMUNOLOGY
- Atg5 but not Atg7 in dendritic cells enhances IL-2 and IFN-γ production by Toxoplasma gondii-reactive CD4+ T cells
- (2015) Elizabeth Liu et al. MICROBES AND INFECTION
- p53 Restoration in Induction and Maintenance of Senescence: Differential Effects in Premalignant and Malignant Tumor Cells
- (2015) Mohamad Harajly et al. MOLECULAR AND CELLULAR BIOLOGY
- Hypoxia-induced autophagy contributes to the invasion of salivary adenoid cystic carcinoma through the HIF-1α/BNIP3 signaling pathway
- (2015) HAIWEI WU et al. Molecular Medicine Reports
- Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells
- (2015) Myriam Catalano et al. Molecular Oncology
- Combination cancer immunotherapy and new immunomodulatory targets
- (2015) Kathleen M. Mahoney et al. NATURE REVIEWS DRUG DISCOVERY
- Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis
- (2015) Samia Afzal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metformin inhibits thyroid cancer cell growth, migration, and EMT through the mTOR pathway
- (2015) Baiyu Han et al. TUMOR BIOLOGY
- Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway
- (2015) Shu-Feng Zhou et al. Drug Design Development and Therapy
- Colorectal cancer-promoting activity of the senescent peritoneal mesothelium
- (2015) Justyna Mikuła-Pietrasik et al. Oncotarget
- MicroRNA-212 negatively regulates starvation induced autophagy in prostate cancer cells by inhibiting SIRT1 and is a modulator of angiogenesis and cellular senescence
- (2015) Malathi Ramalinga et al. Oncotarget
- IL-6 Inhibits Starvation-induced Autophagy via the STAT3/Bcl-2 Signaling Pathway
- (2015) Beibei Qin et al. Scientific Reports
- Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion
- (2015) Min Zhang et al. eLife
- Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from Senescence
- (2015) Grazyna Mosieniak et al. NEOPLASIA
- c-Met is a novel tumor associated antigen for T-cell based immunotherapy against NK/T cell lymphoma
- (2015) Takumi Kumai et al. OncoImmunology
- Classification of current anticancer immunotherapies
- (2015) Lorenzo Galluzzi et al. Oncotarget
- Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination
- (2014) Zhenzhen Zhan et al. Autophagy
- Autophagy promotes radiation-induced senescence but inhibits bystander effects in human breast cancer cells
- (2014) Yao-Huei Huang et al. Autophagy
- Identification of secreted proteins that reflect autophagy dynamics within tumor cells
- (2014) Adam A. Kraya et al. Autophagy
- Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity
- (2014) Michelle Cicchini et al. Autophagy
- Autophagy in non-small cell lung carcinogenesis
- (2014) Shuan Rao et al. Autophagy
- Radiation-induced autophagy potentiates immunotherapy of cancer via up-regulation of mannose 6-phosphate receptor on tumor cells in mice
- (2014) Sungjune Kim et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- STAT3-Mediated Autophagy Dependence Identifies Subtypes of Breast Cancer Where Autophagy Inhibition Can Be Efficacious
- (2014) P. Maycotte et al. CANCER RESEARCH
- The generation of neutrophils in the bone marrow is controlled by autophagy
- (2014) S Rožman et al. CELL DEATH AND DIFFERENTIATION
- Immunotherapy Targeting Folate Receptor Induces Cell Death Associated with Autophagy in Ovarian Cancer
- (2014) Y. Wen et al. CLINICAL CANCER RESEARCH
- TGF-beta Signaling in Cancer Treatment
- (2014) Isabel Fabregat et al. CURRENT PHARMACEUTICAL DESIGN
- Interleukin-6-induced epithelial-mesenchymal transition through signal transducer and activator of transcription 3 in human cervical carcinoma
- (2014) JIN-WEI MIAO et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Feasibility Analysis of p62 (SQSTM1)—Encoding DNA Vaccine as a Novel Cancer Immunotherapy
- (2014) Vladimir L. Gabai et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- Cutting Edge: Generation of Effector Cells That Localize to Mucosal Tissues and Form Resident Memory CD8 T Cells Is Controlled by mTOR
- (2014) Ryan T. Sowell et al. JOURNAL OF IMMUNOLOGY
- New Function of Type I IFN: Induction of Autophagy
- (2014) Hana Schmeisser et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Autophagy is essential for effector CD8+ T cell survival and memory formation
- (2014) Xiaojin Xu et al. NATURE IMMUNOLOGY
- Molecular mechanisms of epithelial–mesenchymal transition
- (2014) Samy Lamouille et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Essential role for autophagy during invariant NKT cell development
- (2014) Mariolina Salio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autophagic degradation of the inhibitory p53 isoform Δ133p53α as a regulatory mechanism for p53-mediated senescence
- (2014) Izumi Horikawa et al. Nature Communications
- Autophagy-Dependent Production of Secreted Factors Facilitates Oncogenic RAS-Driven Invasion
- (2014) R. Lock et al. Cancer Discovery
- Autophagy is a critical regulator of memory CD8+ T cell formation
- (2014) Daniel J Puleston et al. eLife
- ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death
- (2013) Abhishek D. Garg et al. Autophagy
- Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells
- (2013) Yuan-Fei Peng et al. Autophagy
- Sunitinib induces cellular senescence via p53/Dec1 activation in renal cell carcinoma cells
- (2013) Yu Zhu et al. CANCER SCIENCE
- Autophagy promotes hepatocellular carcinoma cell invasion through activation of epithelial–mesenchymal transition
- (2013) Jun Li et al. CARCINOGENESIS
- Mechanisms Governing Metastatic Dormancy and Reactivation
- (2013) Filippo G. Giancotti CELL
- Molecular mechanisms of ATP secretion during immunogenic cell death
- (2013) I Martins et al. CELL DEATH AND DIFFERENTIATION
- Diversity in unconventional protein secretion
- (2013) Catherine Rabouille et al. JOURNAL OF CELL SCIENCE
- Plasma cells require autophagy for sustainable immunoglobulin production
- (2013) Niccolò Pengo et al. NATURE IMMUNOLOGY
- Autophagy and Cellular Senescence Mediated by Sox2 Suppress Malignancy of Cancer Cells
- (2013) Yong-Yeon Cho et al. PLoS One
- Survival and Death Strategies in Glioma Cells: Autophagy, Senescence and Apoptosis Triggered by a Single Type of Temozolomide-Induced DNA Damage
- (2013) Anna V. Knizhnik et al. PLoS One
- Tumor-Derived Autophagosomes (DRibbles) Induce B Cell Activation in a TLR2-MyD88 Dependent Manner
- (2013) Weixia Li et al. PLoS One
- Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia
- (2013) J. Baginska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Why is autophagy important for melanoma? Molecular mechanisms and therapeutic implications
- (2013) Marco Corazzari et al. SEMINARS IN CANCER BIOLOGY
- Autophagy-dependent senescence in response to DNA damage and chronic apoptotic stress
- (2012) Kamini Singh et al. Autophagy
- Proper macrophagic differentiation requires both autophagy and caspase activation
- (2012) Arnaud Jacquel et al. Autophagy
- Blocking the interleukin 2 (IL2)-induced systemic autophagic syndrome promotes profound antitumor effects and limits toxicity
- (2012) Michael T. Lotze et al. Autophagy
- α-TEA as a stimulator of tumor autophagy and enhancer of antigen cross-presentation
- (2012) Tobias Hahn et al. Autophagy
- Induction of autophagy is essential for monocyte-macrophage differentiation
- (2012) Y. Zhang et al. BLOOD
- Inhibiting Systemic Autophagy during Interleukin 2 Immunotherapy Promotes Long-term Tumor Regression
- (2012) X. Liang et al. CANCER RESEARCH
- Cell-Mediated Autophagy Promotes Cancer Cell Survival
- (2012) W. J. Buchser et al. CANCER RESEARCH
- The Vitamin E Analogue -TEA Stimulates Tumor Autophagy and Enhances Antigen Cross-Presentation
- (2012) Y. Li et al. CANCER RESEARCH
- Autophagy Induced by Conventional Chemotherapy Mediates Tumor Cell Sensitivity to Immunotherapy
- (2012) R. Ramakrishnan et al. CANCER RESEARCH
- DEDD Interacts with PI3KC3 to Activate Autophagy and Attenuate Epithelial-Mesenchymal Transition in Human Breast Cancer
- (2012) Q. Lv et al. CANCER RESEARCH
- CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth
- (2012) Claudia Capparelli et al. CELL CYCLE
- Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production
- (2012) Claudia Capparelli et al. CELL CYCLE
- CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, “fueling” tumor growth via paracrine interactions, without an increase in neo-angiogenesis
- (2012) Claudia Capparelli et al. CELL CYCLE
- Autophagy is required for IL-2-mediated fibroblast growth
- (2012) Rui Kang et al. EXPERIMENTAL CELL RESEARCH
- Loss of immunity-supported senescence enhances susceptibility to hepatocellular carcinogenesis and progression in Toll-like receptor 2-deficient mice
- (2012) Heng Lin et al. HEPATOLOGY
- Anticancer Drugs Cause Release of Exosomes with Heat Shock Proteins from Human Hepatocellular Carcinoma Cells That Elicit Effective Natural Killer Cell Antitumor Responsesin Vitro
- (2012) Li-Hong Lv et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IFN- Elicits Macrophage Autophagy via the p38 MAPK Signaling Pathway
- (2012) T. Matsuzawa et al. JOURNAL OF IMMUNOLOGY
- Autophagy Regulates IL-23 Secretion and Innate T Cell Responses through Effects on IL-1 Secretion
- (2012) C. Peral de Castro et al. JOURNAL OF IMMUNOLOGY
- Canonical autophagy dependent on the class III phosphoinositide-3 kinase Vps34 is required for naive T-cell homeostasis
- (2012) T. Willinger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation
- (2012) Hina Kalra et al. PLOS BIOLOGY
- Blocking Hypoxia-Induced Autophagy in Tumors Restores Cytotoxic T-Cell Activity and Promotes Regression
- (2011) M. Z. Noman et al. CANCER RESEARCH
- mTORC1 and mTORC2 Regulate EMT, Motility, and Metastasis of Colorectal Cancer via RhoA and Rac1 Signaling Pathways
- (2011) P. Gulhati et al. CANCER RESEARCH
- Rescue of ΔF508-CFTR Trafficking via a GRASP-Dependent Unconventional Secretion Pathway
- (2011) Heon Yung Gee et al. CELL
- Autophagy promotes T-cell survival through degradation of proteins of the cell death machinery
- (2011) J R Kovacs et al. CELL DEATH AND DIFFERENTIATION
- Tumor-Derived Autophagosome Vaccine: Induction of Cross-Protective Immune Responses against Short-lived Proteins through a p62-Dependent Mechanism
- (2011) C. G. Twitty et al. CLINICAL CANCER RESEARCH
- Autophagy and cytokines
- (2011) James Harris CYTOKINE
- Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β
- (2011) Nicolas Dupont et al. EMBO JOURNAL
- Role of NOD1/CARD4 and NOD2/CARD15 gene polymorphisms in cancer etiology
- (2011) Anton G. Kutikhin HUMAN IMMUNOLOGY
- Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation
- (2011) James Harris et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
- (2011) R. D. Michalek et al. JOURNAL OF IMMUNOLOGY
- Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
- (2011) Tae-Won Kang et al. NATURE
- SASP mediates chemoresistance and tumor-initiating-activity of mesothelioma cells
- (2011) C Canino et al. ONCOGENE
- Autophagy Impairment Induces Premature Senescence in Primary Human Fibroblasts
- (2011) Hyun Tae Kang et al. PLoS One
- Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes
- (2011) M. Narita et al. SCIENCE
- The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
- (2010) Jean-Philippe Coppé et al. Annual Review of Pathology-Mechanisms of Disease
- Role of autophagy in unconventional protein secretion
- (2010) Ravi Manjithaya et al. Autophagy
- In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells
- (2010) Heung Kyu Lee et al. IMMUNITY
- Unconventional secretion of Acb1 is mediated by autophagosomes
- (2010) Juan M. Duran et al. JOURNAL OF CELL BIOLOGY
- Autophagy Regulates Endoplasmic Reticulum Homeostasis and Calcium Mobilization in T Lymphocytes
- (2010) W. Jia et al. JOURNAL OF IMMUNOLOGY
- The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
- (2010) Taro Kawai et al. NATURE IMMUNOLOGY
- Micrometastatic disease and metastatic outgrowth: clinical issues and experimental approaches
- (2009) Patricia M McGowan et al. Future Oncology
- Autophagy mediates the mitotic senescence transition
- (2009) A. R.J. Young et al. GENES & DEVELOPMENT
- Autophagy Is Essential for Mitochondrial Clearance in Mature T Lymphocytes
- (2009) H. H. Pua et al. JOURNAL OF IMMUNOLOGY
- Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
- (2009) Leonardo H Travassos et al. NATURE IMMUNOLOGY
- Efficient Cross-presentation Depends on Autophagy in Tumor Cells
- (2008) Y. Li et al. CANCER RESEARCH
- The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells
- (2008) Zhen Lu et al. JOURNAL OF CLINICAL INVESTIGATION
- Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
- (2008) Jean-Philippe Coppé et al. PLOS BIOLOGY
- Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival
- (2007) Christopher Fung et al. MOLECULAR BIOLOGY OF THE CELL
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started