Autophagy promotes radiation-induced senescence but inhibits bystander effects in human breast cancer cells

Radiation-induced senescence in securin-deficient cancer cells promotes cell invasion involving the IL-6/STAT3 and PDGF-BB/PDGFR pathways

(2013) Yi-Chu Yu et al.   Scientific Reports

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

DEDD Interacts with PI3KC3 to Activate Autophagy and Attenuate Epithelial-Mesenchymal Transition in Human Breast Cancer

(2012) Q. Lv et al.   CANCER RESEARCH

Autophagy and cancer

(2012) Kyeong Sook Choi   EXPERIMENTAL AND MOLECULAR MEDICINE

Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis

(2011) Seon-Jin Lee et al.   Autophagy

Principles and Current Strategies for Targeting Autophagy for Cancer Treatment

(2011) R. K. Amaravadi et al.   CLINICAL CANCER RESEARCH

5-Formylhonokiol exerts anti-angiogenesis activityviainactivating the ERK signaling pathway

(2011) Wei Zhu et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

A kinase shRNA screen links LATS2 and the pRB tumor suppressor

(2011) K. Tschop et al.   GENES & DEVELOPMENT

Four faces of cellular senescence

(2011) Francis Rodier et al.   JOURNAL OF CELL BIOLOGY

Autophagy Impairment Induces Premature Senescence in Primary Human Fibroblasts

(2011) Hyun Tae Kang et al.   PLoS One

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Connecting autophagy to senescence in pathophysiology

(2010) Andrew RJ Young et al.   CURRENT OPINION IN CELL BIOLOGY

Depletion of Securin Induces Senescence After Irradiation and Enhances Radiosensitivity in Human Cancer Cells Regardless of Functional p53 Expression

(2010) Wen-Shu Chen et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Autophagy mediates the process of cellular senescence characterizing bile duct damages in primary biliary cirrhosis

(2010) Motoko Sasaki et al.   LABORATORY INVESTIGATION

Signal transducer and activator of transcription 3 activation up-regulates interleukin-6 autocrine production: a biochemical and genetic study of established cancer cell lines and clinical isolated human cancer cells

(2010) Wei-Lun Huang et al.   Molecular Cancer

Radiation-induced autophagy in normal and cancer cells: Towards novel cytoprotection and radio-sensitization policies?

(2009) Christos E. Zois et al.   Autophagy

Autophagy facilitates oncogene-induced senescence

(2009) Masako Narita et al.   Autophagy

Autophagy, senescence and tumor dormancy in cancer therapy

(2009) David A. Gewirtz   Autophagy

Ionizing radiation-induced bystander effects, potential targets for modulation of radiotherapy

(2009) Joanna Rzeszowska-Wolny et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Autophagy mediates the mitotic senescence transition

(2009) A. R.J. Young et al.   GENES & DEVELOPMENT

Autophagy in tumour suppression and promotion

(2009) Andreas Brech et al.   Molecular Oncology

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols

Clinical biomarkers and imaging for radiotherapy-induced cell death

(2008) Marcel Verheij   CANCER AND METASTASIS REVIEWS

Inflammatory signaling and cellular senescence

(2008) Jian-Lin Ren et al.   CELLULAR SIGNALLING

The tumor microenvironment and its contribution to tumor evolution toward metastasis

(2008) Girieca Lorusso et al.   HISTOCHEMISTRY AND CELL BIOLOGY

In vitro angiogenesis by human umbilical vein endothelial cells (HUVEC) induced by three-dimensional co-culture with glioblastoma cells

(2008) Zhijian Chen et al.   JOURNAL OF NEURO-ONCOLOGY

Regulation of gamma-H2AX and securin contribute to apoptosis by oxaliplatin via a p38 mitogen-activated protein kinase-dependent pathway in human colorectal cancer cells

(2008) Shu-Jun Chiu et al.   TOXICOLOGY LETTERS

PTTG: an important target gene for ovarian cancer therapy

(2008) Siva Panguluri et al.   Journal of Ovarian Research