Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells
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Title
Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 17, Issue 1, Pages 41
Publisher
MDPI AG
Online
2015-12-29
DOI
10.3390/ijms17010041
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Note: Only part of the references are listed.- Global cancer statistics, 2012
- (2015) Lindsey A. Torre et al. CA-A CANCER JOURNAL FOR CLINICIANS
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- (2014) Rebecca Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- The selective Aurora-A kinase inhibitor MLN8237 (alisertib) potently inhibits proliferation of glioblastoma neurosphere tumor stem-like cells and potentiates the effects of temozolomide and ionizing radiation
- (2014) Xin Hong et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration
- (2014) David Heras-Sandoval et al. CELLULAR SIGNALLING
- When Overgrowth Bumps Into Cancer: The PTEN-Opathies
- (2013) JESSICA MESTER et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS
- Aurora kinase A (AURKA) expression in colorectal cancer liver metastasis is associated with poor prognosis
- (2013) J A C M Goos et al. BRITISH JOURNAL OF CANCER
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- (2013) N. Zhou et al. CLINICAL CANCER RESEARCH
- Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012
- (2013) J. Ferlay et al. EUROPEAN JOURNAL OF CANCER
- The mitotic kinase Aurora-A promotes distant metastases by inducing epithelial-to-mesenchymal transition in ERα+ breast cancer cells
- (2013) A B D'Assoro et al. ONCOGENE
- Relationship of increased aurora kinase A gene copy number, prognosis and response to chemotherapy in patients with metastatic colorectal cancer
- (2012) E Dotan et al. BRITISH JOURNAL OF CANCER
- Beyond bevacizumab: new anti-VEGF strategies in colorectal cancer
- (2012) Teresa Troiani et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- The Aurora Kinase A Inhibitor MLN8237 Enhances Cisplatin-Induced Cell Death in Esophageal Adenocarcinoma Cells
- (2012) V. Sehdev et al. MOLECULAR CANCER THERAPEUTICS
- Autophagy and cancer cell metabolism
- (2012) Fred Lozy et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- The Ins and Outs of the Epithelial to Mesenchymal Transition in Health and Disease
- (2011) M. Angela Nieto Annual Review of Cell and Developmental Biology
- Autophagy: Renovation of Cells and Tissues
- (2011) Noboru Mizushima et al. CELL
- An Update on the Current and Emerging Targeted Agents in Metastatic Colorectal Cancer
- (2011) Edward Chu Clinical Colorectal Cancer
- Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks
- (2011) S. Alers et al. MOLECULAR AND CELLULAR BIOLOGY
- Epithelial-to-mesenchymal transition in prostate cancer: paradigm or puzzle?
- (2011) Jones T. Nauseef et al. Nature Reviews Urology
- A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma
- (2010) G. Gorgun et al. BLOOD
- Aurora-A Is Essential for the Tumorigenic Capacity and Chemoresistance of Colorectal Cancer Stem Cells
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- Adjuvant colon cancer chemotherapy: where we are and where we'll go
- (2010) L. Lombardi et al. CANCER TREATMENT REVIEWS
- mTOR regulation of autophagy
- (2010) Chang Hwa Jung et al. FEBS LETTERS
- Aurora-A and hBora Join the Game of Polo
- (2009) L. Macurek et al. CANCER RESEARCH
- The basics of epithelial-mesenchymal transition
- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
- Clinical Experience with Aurora Kinase Inhibitors: A Review
- (2009) D. S. Boss et al. ONCOLOGIST
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- (2008) O. Gautschi et al. CLINICAL CANCER RESEARCH
- NCAM-induced focal adhesion assembly: a functional switch upon loss of E-cadherin
- (2008) Francois Lehembre et al. EMBO JOURNAL
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- (2008) G. Tang et al. HUMAN MOLECULAR GENETICS
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