Survival and Death Strategies in Glioma Cells: Autophagy, Senescence and Apoptosis Triggered by a Single Type of Temozolomide-Induced DNA Damage

Autophagy-dependent senescence in response to DNA damage and chronic apoptotic stress

(2012) Kamini Singh et al.   Autophagy

Processing of O6-methylguanine into DNA double-strand breaks requires two rounds of replication whereas apoptosis is also induced in subsequent cell cycles

(2011) Steve Quiros et al.   CELL CYCLE

Resveratrol enhances the therapeutic effect of temozolomide against malignant glioma in vitro and in vivo by inhibiting autophagy

(2011) Chien-Ju Lin et al.   FREE RADICAL BIOLOGY AND MEDICINE

DNA damage and autophagy

(2011) Humberto Rodriguez-Rocha et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Rad51 and BRCA2 - New Molecular Targets for Sensitizing Glioma Cells to Alkylating Anticancer Drugs

(2011) Steve Quiros et al.   PLoS One

Autophagosome Formation and Molecular Mechanism of Autophagy

(2010) Isei Tanida   ANTIOXIDANTS & REDOX SIGNALING

Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway

(2010) Li-Hsin Chen et al.   BIOCHEMICAL PHARMACOLOGY

Discovery of a Novel Function for Human Rad51

(2010) Jay M. Sage et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

(2010) A. Alexander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs and p53

(2009) S C Naumann et al.   BRITISH JOURNAL OF CANCER

Temozolomide in malignant gliomas: current use and future targets

(2009) J. Lee Villano et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Life and death partners: apoptosis, autophagy and the cross-talk between them

(2009) A Eisenberg-Lerner et al.   CELL DEATH AND DIFFERENTIATION

Eating to exit: autophagy-enabled senescence revealed

(2009) E. White et al.   GENES & DEVELOPMENT

Autophagy mediates the mitotic senescence transition

(2009) A. R.J. Young et al.   GENES & DEVELOPMENT

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols

Lipid mediators of autophagy in stress-induced premature senescence of endothelial cells

(2008) Susann Patschan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O6-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEs

(2008) Wynand P. Roos et al.   DNA REPAIR