Antagonism of Bradykinin B2 Receptor Prevents Inflammatory Responses in Human Endothelial Cells by Quenching the NF-kB Pathway Activation

Blockade of nociceptive sensory afferent activity of the rat knee joint by the bradykinin B2 receptor antagonist fasitibant

(2013) A. Gomis et al.   OSTEOARTHRITIS AND CARTILAGE

Endothelial Nuclear Factor-κB–Dependent Regulation of Arteriogenesis and Branching

(2012) Daniela Tirziu et al.   CIRCULATION

Icatibant, the bradykinin B2 receptor antagonist with target to the interconnected kinin systems

(2012) Delphine Charignon et al.   EXPERT OPINION ON PHARMACOTHERAPY

Clinical efficacy of icatibant in the treatment of acute hereditary angioedema during the FAST-3 trial

(2012) Murat Bas¸   Expert Review of Clinical Immunology

Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo

(2012) Fabrizio Orsenigo et al.   Nature Communications

Bradykinin receptor 2 extends inflammatory cell recruitment in a model of acute gouty arthritis

(2011) Odette M. Shaw et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anti-inflammatory synergy of MEN16132, a kinin B2 receptor antagonist, and dexamethasone in carrageenan-induced knee joint arthritis in rats

(2010) C Valenti et al.   BRITISH JOURNAL OF PHARMACOLOGY

Bradykinin and B2 receptor antagonism in rat and human articular chondrocytes

(2010) S Meini et al.   BRITISH JOURNAL OF PHARMACOLOGY

Comparison of the molecular interactions of two antagonists, MEN16132 or icatibant, at the human kinin B2 receptor

(2010) S Meini et al.   BRITISH JOURNAL OF PHARMACOLOGY

Tissue Kallikrein Is Essential for Invasive Capacity of Circulating Proangiogenic Cells

(2010) Gaia Spinetti et al.   CIRCULATION RESEARCH

Radioligand binding characterization of the bradykinin B2 receptor in the rabbit and pig ileal smooth muscle

(2010) Stefania Meini et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Aβ peptides accelerate the senescence of endothelial cells in vitro and in vivo, impairing angiogenesis

(2010) Sandra Donnini et al.   FASEB JOURNAL

Novel effects mediated by bradykinin and pharmacological characterization of bradykinin B2 receptor antagonism in human synovial fibroblasts

(2009) F Bellucci et al.   BRITISH JOURNAL OF PHARMACOLOGY

Prostaglandin E 2 Primes the Angiogenic Switch via a Synergic Interaction With the Fibroblast Growth Factor-2 Pathway

(2009) Federica Finetti et al.   CIRCULATION RESEARCH

Pharmacological characterization of the bradykinin B2 receptor antagonist MEN16132 in rat in vitro bioassays

(2009) Stefania Meini et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Bradykinin receptor antagonists – a review of the patent literature 2005 – 2008

(2009) Christopher I Fincham et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Effect of Intra-articular 4-(S)-Amino-5-(4-  piperazino)-5-oxopentyl](trimethyl)ammonium chloride hydrochloride (MEN16132), a Kinin B2 Receptor Antagonist, on Nociceptive Response in Monosodium Iodoacetate-Induced Experimental Osteoarthritis in Rats

(2009) C. Cialdai et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Knee osteoarthritis: a role for bradykinin?

(2008) S. Meini et al.   INFLAMMATION RESEARCH

Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5

(2008) Andrea Taddei et al.   NATURE CELL BIOLOGY

MEN16132, a kinin B2 receptor antagonist, prevents the endogenous bradykinin effects in guinea-pig airways

(2007) Claudio Valenti et al.   EUROPEAN JOURNAL OF PHARMACOLOGY