Redundancy and divergence in the amyloid precursor protein family

APLP2 regulates neuronal stem cell differentiation during cortical development

(2013) S. A. M. Shariati et al.   JOURNAL OF CELL SCIENCE

An Update of DIVERGE Software for Functional Divergence Analysis of Protein Family

(2013) Xun Gu et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Drosophila Homologue of the Amyloid Precursor Protein Is a Conserved Modulator of Wnt PCP Signaling

(2013) Alessia Soldano et al.   PLOS BIOLOGY

Evolution of Synapse Complexity and Diversity

(2012) Richard D. Emes et al.   Annual Review of Neuroscience

Cyclin-Dependent Kinase Inhibitor p21 Controls Adult Neural Stem Cell Expansion by Regulating Sox2 Gene Expression

(2012) M. Ángeles Marqués-Torrejón et al.   Cell Stem Cell

Pancortins interact with amyloid precursor protein and modulate cortical cell migration

(2012) H. C. Rice et al.   DEVELOPMENT

APL-1, the Alzheimer's Amyloid Precursor Protein in Caenorhabditis elegans, Modulates Multiple Metabolic Pathways Throughout Development

(2012) C. Y. Ewald et al.   GENETICS

Roles of the amyloid precursor protein family in the peripheral nervous system

(2012) John H. Caldwell et al.   MECHANISMS OF DEVELOPMENT

Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function

(2012) Brea Midthune et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Amyloid precursor protein (APP) regulates synaptic structure and function

(2012) Sheue-Houy Tyan et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Reelin-dependent ApoER2 downregulation uncouples newborn neurons from progenitor cells

(2012) F. J. Perez-Martinez et al.   Biology Open

Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex

(2011) Dorothee Aydin et al.   BMC GENOMICS

APP physiological and pathophysiological functions: insights from animal models

(2011) Qinxi Guo et al.   CELL RESEARCH

Reelin sets the pace of neocortical neurogenesis

(2011) J. Lakoma et al.   DEVELOPMENT

APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP

(2011) Sascha W Weyer et al.   EMBO JOURNAL

Structural features of the KPI domain control APP dimerization, trafficking, and processing

(2011) Naouel Ben Khalifa et al.   FASEB JOURNAL

A Single Tyrosine Residue in the Amyloid Precursor Protein Intracellular Domain Is Essential for Developmental Function

(2011) Alessia P. M. Barbagallo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid Precursor Protein Revisited

(2011) Qinxi Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

APP is Phosphorylated by TrkA and Regulates NGF/TrkA Signaling

(2011) C. Matrone et al.   JOURNAL OF NEUROSCIENCE

Biology and pathophysiology of the amyloid precursor protein

(2011) Hui Zheng et al.   Molecular Neurodegeneration

Reelin Regulates Cadherin Function via Dab1/Rap1 to Control Neuronal Migration and Lamination in the Neocortex

(2011) Santos J. Franco et al.   NEURON

DISC1-binding proteins in neural development, signalling and schizophrenia

(2011) Nicholas J. Bradshaw et al.   NEUROPHARMACOLOGY

The Intracellular Threonine of Amyloid Precursor Protein That Is Essential for Docking of Pin1 Is Dispensable for Developmental Function

(2011) Alessia P. M. Barbagallo et al.   PLoS One

Accelerated Recruitment of New Brain Development Genes into the Human Genome

(2011) Yong E. Zhang et al.   PLOS BIOLOGY

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

(2011) Graciana Diez-Roux et al.   PLOS BIOLOGY

Role of APP for dendritic spine formation and stability

(2011) Christian K. E. Jung et al.   EXPERIMENTAL BRAIN RESEARCH

Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease

(2010) James A. Duce et al.   CELL

Cortical progenitor expansion, self-renewal and neurogenesis—a polarized perspective

(2010) Simone A Fietz et al.   CURRENT OPINION IN NEUROBIOLOGY

Biochemical and Functional Interaction of Disrupted-in-Schizophrenia 1 and Amyloid Precursor Protein Regulates Neuronal Migration during Mammalian Cortical Development

(2010) T. L. Young-Pearse et al.   JOURNAL OF NEUROSCIENCE

In Vivo Reconstitution of  -Secretase in Drosophila Results in Substrate Specificity

(2010) D. Stempfle et al.   MOLECULAR AND CELLULAR BIOLOGY

Neurogenic radial glia in the outer subventricular zone of human neocortex

(2010) David V. Hansen et al.   NATURE

OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling

(2010) Simone A Fietz et al.   NATURE NEUROSCIENCE

The evolution of gene duplications: classifying and distinguishing between models

(2010) Hideki Innan et al.   NATURE REVIEWS GENETICS

The secretases: enzymes with therapeutic potential in Alzheimer disease

(2010) Bart De Strooper et al.   Nature Reviews Neurology

Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines

(2010) K.J. Lee et al.   NEUROSCIENCE

Proteases and Proteolysis in Alzheimer Disease: A Multifactorial View on the Disease Process

(2010) Bart De Strooper   PHYSIOLOGICAL REVIEWS

Intracellular Trafficking and Synaptic Function of APL-1 in Caenorhabditis elegans

(2010) Mary Wiese et al.   PLoS One

Tyr682 in the Intracellular Domain of APP Regulates Amyloidogenic APP Processing In Vivo

(2010) Alessia P. M. Barbagallo et al.   PLoS One

Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP

(2010) H. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution in protein interaction networks: co-evolution, rewiring and the role of duplication

(2009) David L. Robertson et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors

(2009) Kristin T. Jacobsen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The 28-amino acid form of an APLP1-derived Aβ-like peptide is a surrogate marker for Aβ42 production in the central nervous system

(2009) Kanta Yanagida et al.   EMBO Molecular Medicine

Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2

(2009) D. Kaden et al.   JOURNAL OF CELL SCIENCE

 -Secretase Inhibition Reduces Spine Density In Vivo via an Amyloid Precursor Protein-Dependent Pathway

(2009) T. Bittner et al.   JOURNAL OF NEUROSCIENCE

Amyloid Precursor Protein Regulates Cav1.2 L-type Calcium Channel Levels and Function to Influence GABAergic Short-Term Plasticity

(2009) L. Yang et al.   JOURNAL OF NEUROSCIENCE

Interaction of Reelin with Amyloid Precursor Protein Promotes Neurite Outgrowth

(2009) H.-S. Hoe et al.   JOURNAL OF NEUROSCIENCE

Presynaptic and Postsynaptic Interaction of the Amyloid Precursor Protein Promotes Peripheral and Central Synaptogenesis

(2009) Z. Wang et al.   JOURNAL OF NEUROSCIENCE

Tissue specificity and the human protein interaction network

(2009) Alice Bossi et al.   Molecular Systems Biology

The origin and evolution of synapses

(2009) Tomás J. Ryan et al.   NATURE REVIEWS NEUROSCIENCE

Functional and Evolutionary Insights into Human Brain Development through Global Transcriptome Analysis

(2009) Matthew B. Johnson et al.   NEURON

 -Secretase Heterogeneity in the Aph1 Subunit: Relevance for Alzheimer's Disease

(2009) L. Serneels et al.   SCIENCE

Evolutionary expansion and anatomical specialization of synapse proteome complexity

(2008) Richard D Emes et al.   NATURE NEUROSCIENCE

Neurotoxic effects induced by the Drosophila amyloid-β peptide suggest a conserved toxic function

(2008) Katia Carmine-Simmen et al.   NEUROBIOLOGY OF DISEASE

A mechanism for inside-out lamination in the neocortex

(2008) Jonathan A. Cooper   TRENDS IN NEUROSCIENCES