ALDH2 Activity Reduces Mitochondrial Oxygen Reserve Capacity in Endothelial Cells and Induces Senescence Properties

Cross-talk between endogenous H 2 S and NO accounts for vascular protective activity of the metal-nonoate Zn(PipNONO)Cl

(2018) Martina Monti et al.   BIOCHEMICAL PHARMACOLOGY

PGE2 mediates EGFR internalization and nuclear translocation via caveolin endocytosis promoting its transcriptional activity and proliferation in human NSCLC cells

(2018) Lorenzo Bazzani et al.   Oncotarget

The Aging Cardiovascular System

(2017) Francesco Paneni et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Alisporivir rescues defective mitochondrial respiration in Duchenne muscular dystrophy

(2017) Marco Schiavone et al.   PHARMACOLOGICAL RESEARCH

Inhibition of cell cycle progression by the hydroxytyrosol–cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells

(2017) Erika Terzuoli et al.   Oncotarget

Efficacy of AdipoDren® in Reducing Interleukin-1-Induced Lymphatic Endothelial Hyperpermeability

(2016) Valerio Ciccone et al.   JOURNAL OF VASCULAR RESEARCH

L-Arginine Affects Aerobic Capacity and Muscle Metabolism in MELAS (Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-Like Episodes) Syndrome

(2015) Lance H. Rodan et al.   PLoS One

Endothelial Cell Senescence and Age-Related Vascular Diseases

(2014) Xiao-Li Tian et al.   Journal of Genetics and Genomics

Cellular senescence: from physiology to pathology

(2014) Daniel Muñoz-Espín et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Targeting Aldehyde Dehydrogenase 2: New Therapeutic Opportunities

(2014) Che-Hong Chen et al.   PHYSIOLOGICAL REVIEWS

Reactive Oxygen Species in Inflammation and Tissue Injury

(2013) Manish Mittal et al.   ANTIOXIDANTS & REDOX SIGNALING

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Mitochondria and Endothelial Function

(2013) Matthew A. Kluge et al.   CIRCULATION RESEARCH

Mitochondrial aldehyde dehydrogenase-2 activation prevents  -amyloid-induced endothelial cell dysfunction and restores angiogenesis

(2013) R. Solito et al.   JOURNAL OF CELL SCIENCE

The effects of idebenone on mitochondrial bioenergetics

(2011) Valentina Giorgio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The Neurovascular Link in Health and Disease: Molecular Mechanisms and Therapeutic Implications

(2011) Annelies Quaegebeur et al.   NEURON

Mitochondrial aldehyde dehydrogenase and cardiac diseases

(2010) Che-Hong Chen et al.   CARDIOVASCULAR RESEARCH

Aβ peptides accelerate the senescence of endothelial cells in vitro and in vivo, impairing angiogenesis

(2010) Sandra Donnini et al.   FASEB JOURNAL

Mitochondrial reserve capacity in endothelial cells: The impact of nitric oxide and reactive oxygen species

(2010) Brian P. Dranka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of Angiogenesis by Oxygen and Metabolism

(2009) Peter Fraisl et al.   DEVELOPMENTAL CELL

Vascular endothelial senescence: from mechanisms to pathophysiology

(2008) Jorge D. Erusalimsky   JOURNAL OF APPLIED PHYSIOLOGY

Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart

(2008) Che-Hong Chen et al.   SCIENCE