B-ALL Complexity: Is Targeted Therapy Still A Valuable Approach for Pediatric Patients?
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
B-ALL Complexity: Is Targeted Therapy Still A Valuable Approach for Pediatric Patients?
Authors
Keywords
-
Journal
Cancers
Volume 12, Issue 12, Pages 3498
Publisher
MDPI AG
Online
2020-11-24
DOI
10.3390/cancers12123498
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Role Played by Wnt/β-Catenin Signaling Pathway in Acute Lymphoblastic Leukemia
- (2020) Francesca Chiarini et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Current Genomic and Molecular Landscape of Philadelphia-like Acute Lymphoblastic Leukemia
- (2020) Parveen Shiraz et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Genomic landscape of pediatric B-other acute lymphoblastic leukemia in a consecutive European cohort
- (2019) Marketa Zaliova et al. HAEMATOLOGICA
- PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia
- (2019) Zhaohui Gu et al. NATURE GENETICS
- Wnt5a and ROR1 activate non-canonical Wnt signaling via RhoA in TCF3-PBX1 acute lymphoblastic leukemia and highlight new treatment strategies via Bcl-2 co-targeting
- (2019) Hanna Karvonen et al. ONCOGENE
- NUTM1 is a recurrent fusion gene partner in B cell precursor acute lymphoblastic leukemia associated with increased expression of genes on chromosome band 10p12.31-12.2
- (2019) Femke M Hormann et al. HAEMATOLOGICA
- BCL-2 is a Therapeutic Target For Hypodiploid B-Lineage Acute Lymphoblastic Leukemia
- (2019) Ernesto Diaz-Flores et al. CANCER RESEARCH
- Advances in understanding the mechanisms of evasive and innate resistance to mTOR inhibition in cancer cells
- (2019) Francesca Charini et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Predisposing germline mutations in high hyperdiploid acute lymphoblastic leukemia in children
- (2019) Adam J. de Smith et al. GENES CHROMOSOMES & CANCER
- Efficacy of Tyrosine Kinase Inhibitors in Ph-like Acute Lymphoblastic Leukemia harboring ABL-class Rearrangements
- (2019) Ilaria Tanasi et al. BLOOD
- Crosstalks of GSK3 signaling with the mTOR network and effects on targeted therapy of cancer
- (2019) Camilla Evangelisti et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- T cell acute lymphoblastic leukemia (T-ALL): New insights into the cellular origins and infiltration mechanisms common and unique among hematologic malignancies
- (2018) Eduardo Vadillo et al. BLOOD REVIEWS
- Pre-B acute lymphoblastic leukaemia recurrent fusion, EP300-ZNF384, is associated with a distinct gene expression
- (2018) Barbara J. McClure et al. BRITISH JOURNAL OF CANCER
- Cotargeting BCL-2 and PI3K Induces BAX-Dependent Mitochondrial Apoptosis in AML Cells
- (2018) Mohamed Rahmani et al. CANCER RESEARCH
- The roles of Wnt/β-catenin pathway in tissue development and regenerative medicine
- (2018) Maryam Majidinia et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Targeting the phosphatidylinositol 3-kinase/Akt/mechanistic target of rapamycin signaling pathway in B-lineage acute lymphoblastic leukemia: An update
- (2018) Carolina Simioni et al. JOURNAL OF CELLULAR PHYSIOLOGY
- TP53 Germline Variations Influence the Predisposition and Prognosis of B-Cell Acute Lymphoblastic Leukemia in Children
- (2018) Maoxiang Qian et al. JOURNAL OF CLINICAL ONCOLOGY
- Venetoclax for Patients With Chronic Lymphocytic Leukemia With 17p Deletion: Results From the Full Population of a Phase II Pivotal Trial
- (2018) Stephan Stilgenbauer et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase I trial of the mTOR inhibitor everolimus in combination with multi-agent chemotherapy in relapsed childhood acute lymphoblastic leukemia
- (2018) Andrew E. Place et al. PEDIATRIC BLOOD & CANCER
- Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosome–like acute B-cell lymphoblastic leukemia
- (2018) Qi Zhang et al. Oncotarget
- PAX5 P80R mutation identifies a novel subtype of B-cell precursor acute lymphoblastic leukemia with favorable outcome
- (2018) Marie Passet et al. BLOOD
- NUT Carcinoma: Clinicopathologic features, pathogenesis, and treatment
- (2018) Christopher A. French PATHOLOGY INTERNATIONAL
- Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases
- (2018) Jian-Feng Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ETV6/RUNX1 -like acute lymphoblastic leukemia: A novel B-cell precursor leukemia subtype associated with the CD27/CD44 immunophenotype
- (2017) Marketa Zaliova et al. GENES CHROMOSOMES & CANCER
- Phosphatidylinositol 3-kinase inhibition potentiates glucocorticoid response in B-cell acute lymphoblastic leukemia
- (2017) Cecilia Evangelisti et al. JOURNAL OF CELLULAR PHYSIOLOGY
- High Frequency and Poor Outcome of Philadelphia Chromosome–Like Acute Lymphoblastic Leukemia in Adults
- (2017) Kathryn G. Roberts et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase I First-in-Human Study of Venetoclax in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma
- (2017) Matthew S. Davids et al. JOURNAL OF CLINICAL ONCOLOGY
- RAS pathway mutations as a predictive biomarker for treatment adaptation in pediatric B-cell precursor acute lymphoblastic leukemia
- (2017) I S Jerchel et al. LEUKEMIA
- The pan-BCL-2-blocker obatoclax (GX15-070) and the PI3-kinase/mTOR-inhibitor BEZ235 produce cooperative growth-inhibitory effects in ALL cells
- (2017) Gabriele Stefanzl et al. Oncotarget
- The PI3Kδ Inhibitor Idelalisib Inhibits Homing in an in Vitro and in Vivo Model of B ALL
- (2017) Etai Adam et al. Cancers
- Venetoclax responses of pediatric ALL xenografts reveal sensitivity of MLL-rearranged leukemia
- (2016) S. L. Khaw et al. BLOOD
- EBF1-PDGFRB fusion in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL): genetic profile and clinical implications
- (2016) C. Schwab et al. BLOOD
- Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukemia
- (2016) Julie A. E. Irving et al. BLOOD
- The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
- (2016) D. A. Arber et al. BLOOD
- Targeting mTOR for the treatment of B cell malignancies
- (2016) Jong-Hoon Scott Lee et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia
- (2016) Ilaria Iacobucci et al. CANCER CELL
- Venetoclax: First Global Approval
- (2016) Emma D. Deeks DRUGS
- BET inhibitors in cancer therapeutics: a patent review
- (2016) Anirban Ghoshal et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- How do tumor cells respond to HDAC inhibition?
- (2016) Andrea Newbold et al. FEBS Journal
- Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities ofEP300andCREBBP
- (2016) Maoxiang Qian et al. GENOME RESEARCH
- ZNF384 -related fusion genes define a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with a characteristic immunotype
- (2016) Shinsuke Hirabayashi et al. HAEMATOLOGICA
- MEF2D-BCL9 Fusion Gene Is Associated With High-Risk Acute B-Cell Precursor Lymphoblastic Leukemia in Adolescents
- (2016) Kyogo Suzuki et al. JOURNAL OF CLINICAL ONCOLOGY
- A review of new agents evaluated against pediatric acute lymphoblastic leukemia by the Pediatric Preclinical Testing Program
- (2016) L Jones et al. LEUKEMIA
- The role of the RAS pathway in iAMP21-ALL
- (2016) S L Ryan et al. LEUKEMIA
- CBP/p300 acetyltransferase activity in hematologic malignancies
- (2016) Ritika Dutta et al. MOLECULAR GENETICS AND METABOLISM
- Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults
- (2016) Takahiko Yasuda et al. NATURE GENETICS
- Deregulation of DUX4 and ERG in acute lymphoblastic leukemia
- (2016) Jinghui Zhang et al. NATURE GENETICS
- New Agents to Treat Chronic Lymphocytic Leukemia
- (2016) NEW ENGLAND JOURNAL OF MEDICINE
- Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia
- (2016) Andrew W. Roberts et al. NEW ENGLAND JOURNAL OF MEDICINE
- Frequency and outcome of pediatric acute lymphoblastic leukemia withZNF384gene rearrangements including a novel translocation resulting in anARID1B/ZNF384gene fusion
- (2016) Mary Shago et al. PEDIATRIC BLOOD & CANCER
- Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia
- (2016) Koichi Oshima et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia
- (2016) Henrik Lilljebjörn et al. Nature Communications
- Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia
- (2016) Zhaohui Gu et al. Nature Communications
- Efficacy and Biological Correlates of Response in a Phase II Study of Venetoclax Monotherapy in Patients with Acute Myelogenous Leukemia
- (2016) M. Konopleva et al. Cancer Discovery
- Clinical Response of Carcinomas Harboring the BRD4-NUT Oncoprotein to the Targeted Bromodomain Inhibitor OTX015/MK-8628
- (2016) A. Stathis et al. Cancer Discovery
- The fusion protein SS18-SSX1 employs core Wnt pathway transcription factors to induce a partial Wnt signature in synovial sarcoma
- (2016) Luisa Cironi et al. Scientific Reports
- ZNF384 -related fusion genes define a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with a characteristic immunotype
- (2016) Shinsuke Hirabayashi et al. HAEMATOLOGICA
- Bromodomain inhibitor OTX015 in patients with acute leukaemia: a dose-escalation, phase 1 study
- (2016) Céline Berthon et al. Lancet Haematology
- MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia
- (2015) C. L. Jones et al. BLOOD
- Essential control of early B-cell development by Mef2 transcription factors
- (2015) J. Herglotz et al. BLOOD
- Outcome of children with hypodiploid ALL treated with risk-directed therapy based on MRD levels
- (2015) Charles G. Mullighan et al. BLOOD
- PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia
- (2015) J. Dang et al. BLOOD
- BH3 Inhibitor Sensitivity and Bcl-2 Dependence in Primary Acute Lymphoblastic Leukemia Cells
- (2015) S. E. Alford et al. CANCER RESEARCH
- Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL
- (2015) M. C. Stubbs et al. CLINICAL CANCER RESEARCH
- The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains
- (2015) Artyom A. Alekseyenko et al. GENES & DEVELOPMENT
- BCR-ABL1-like cases in pediatric acute lymphoblastic leukemia: a comparison between DCOG/Erasmus MC and COG/St. Jude signatures
- (2015) J. M. Boer et al. HAEMATOLOGICA
- Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration
- (2015) Ching-Hon Pui et al. JOURNAL OF CLINICAL ONCOLOGY
- A novel recurrent EP300–ZNF384 gene fusion in B-cell precursor acute lymphoblastic leukemia
- (2015) Y Gocho et al. LEUKEMIA
- A functional polymorphism in the CEBPE gene promoter influences acute lymphoblastic leukemia risk through interaction with the hematopoietic transcription factor Ikaros
- (2015) J L Wiemels et al. LEUKEMIA
- Transcriptional plasticity promotes primary and acquired resistance to BET inhibition
- (2015) Philipp Rathert et al. NATURE
- BET inhibitor resistance emerges from leukaemia stem cells
- (2015) Chun Yew Fong et al. NATURE
- The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia
- (2015) Kajsa Paulsson et al. NATURE GENETICS
- Genomics and drug profiling of fatal TCF3-HLF−positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options
- (2015) Ute Fischer et al. NATURE GENETICS
- Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia
- (2015) Xiaotu Ma et al. Nature Communications
- BCR-ABL1-like cases in pediatric acute lymphoblastic leukemia: a comparison between DCOG/Erasmus MC and COG/St. Jude signatures
- (2015) J. M. Boer et al. HAEMATOLOGICA
- Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia
- (2015) Kathryn G. Roberts et al. NEW ENGLAND JOURNAL OF MEDICINE
- Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment
- (2015) Alberto M. Martelli et al. Oncotarget
- Therapeutic Targeting of c-Myc in T-Cell Acute Lymphoblastic Leukemia (T-ALL)
- (2015) Marie Loosveld et al. Oncotarget
- c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells
- (2014) J. E. Roderick et al. BLOOD
- Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition
- (2014) J. Irving et al. BLOOD
- Wnt inhibition leads to improved chemosensitivity in paediatric acute lymphoblastic leukaemia
- (2014) Smita Dandekar et al. BRITISH JOURNAL OF HAEMATOLOGY
- Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia
- (2014) G. J. Liu et al. GENES & DEVELOPMENT
- Towards personalized therapy in pediatric acute lymphoblastic leukemia: RAS mutations and prednisolone resistance
- (2014) I. M. Aries et al. HAEMATOLOGICA
- Adult B-cell acute lymphoblastic leukemia cells display decreased PTEN activity and constitutive hyperactivation of PI3K/Akt pathway despite high PTEN protein levels
- (2014) A. M. Gomes et al. HAEMATOLOGICA
- Targeting STAT5 in Hematologic Malignancies through Inhibition of the Bromodomain and Extra-Terminal (BET) Bromodomain Protein BRD2
- (2014) S. Liu et al. MOLECULAR CANCER THERAPEUTICS
- TKI dasatinib monotherapy for a patient with Ph-like ALL bearingATF7IP/PDGFRBtranslocation
- (2014) Kenichiro Kobayashi et al. PEDIATRIC BLOOD & CANCER
- Blockade of oncogenic I B kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors
- (2014) M. Ceribelli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Maturation Stage of T-cell Acute Lymphoblastic Leukemia Determines BCL-2 versus BCL-XL Dependence and Sensitivity to ABT-199
- (2014) T. N. Chonghaile et al. Cancer Discovery
- Genomic and pharmacogenetic studies of childhood acute lymphoblastic leukemia
- (2014) Ching-Hon Pui Frontiers of Medicine
- Targeting the PI3K/mTOR Pathway in Pediatric Hematologic Malignancies
- (2014) Sarah K. Tasian et al. Frontiers in Oncology
- Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL
- (2013) A. van der Veer et al. BLOOD
- Novel childhood ALL susceptibility locus BMI1-PIP4K2A is specifically associated with the hyperdiploid subtype
- (2013) K. M. Walsh et al. BLOOD
- ABT-199 selectively inhibits BCL2 but not BCL2L1 and efficiently induces apoptosis of chronic lymphocytic leukaemic cells but not platelets
- (2013) Meike Vogler et al. BRITISH JOURNAL OF HAEMATOLOGY
- Cancer statistics, 2013
- (2013) Rebecca Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Wnt pathway contributes to the protection by bone marrow stromal cells of acute lymphoblastic leukemia cells and is a potential therapeutic target
- (2013) Yang Yang et al. CANCER LETTERS
- PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET Bromodomains
- (2013) S. Picaud et al. CANCER RESEARCH
- Successful tyrosine kinase inhibitor therapy in a refractory B-cell precursor acute lymphoblastic leukemia with EBF1-PDGFRB fusion
- (2013) E. Lengline et al. HAEMATOLOGICA
- Tyrosine Kinase Inhibitor Therapy Induces Remission in a Patient With Refractory EBF1-PDGFRB–Positive Acute Lymphoblastic Leukemia
- (2013) Brent W. Weston et al. JOURNAL OF CLINICAL ONCOLOGY
- A Phase I Study of EZN-3042, a Novel Survivin Messenger Ribonucleic Acid (mRNA) Antagonist, Administered in Combination With Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL)
- (2013) Elizabeth A. Raetz et al. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
- Inherited susceptibility to pre B-ALL caused by germline transmission of PAX5 c.547G>A
- (2013) F Auer et al. LEUKEMIA
- An international study of intrachromosomal amplification of chromosome 21 (iAMP21): cytogenetic characterization and outcome
- (2013) C J Harrison et al. LEUKEMIA
- Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers
- (2013) Georgia Hatzivassiliou et al. NATURE
- The genomic landscape of hypodiploid acute lymphoblastic leukemia
- (2013) Linda Holmfeldt et al. NATURE GENETICS
- A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia
- (2013) Sohela Shah et al. NATURE GENETICS
- Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia
- (2013) E J Gang et al. ONCOGENE
- SS18-SSX fusion protein-induced Wnt/β-catenin signaling is a therapeutic target in synovial sarcoma
- (2013) M Trautmann et al. ONCOGENE
- Wnt Signaling in Normal and Malignant Hematopoiesis
- (2013) W. Lento et al. Cold Spring Harbor Perspectives in Biology
- BET inhibition as a single or combined therapeutic approach in primary paediatric B-precursor acute lymphoblastic leukaemia
- (2013) D Da Costa et al. Blood Cancer Journal
- Targeting the Wnt Pathway in Synovial Sarcoma Models
- (2013) W. Barham et al. Cancer Discovery
- Aberrant STAT5 and PI3K/mTOR pathway signaling occurs in human CRLF2-rearranged B-precursor acute lymphoblastic leukemia
- (2012) S. K. Tasian et al. BLOOD
- BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia
- (2012) C. J. Ott et al. BLOOD
- Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia
- (2012) S. L. Maude et al. BLOOD
- Cancer Epigenetics: From Mechanism to Therapy
- (2012) Mark A. Dawson et al. CELL
- Preclinical activity of LBH589 alone or in combination with chemotherapy in a xenogeneic mouse model of human acute lymphoblastic leukemia
- (2012) A Vilas-Zornoza et al. LEUKEMIA
- The complex world of WNT receptor signalling
- (2012) Christof Niehrs NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia
- (2011) E. Park et al. BLOOD
- Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies
- (2011) L. E. Hogan et al. BLOOD
- Overexpression of LEF1 predicts unfavorable outcome in adult patients with B-precursor acute lymphoblastic leukemia
- (2011) A. Kuhnl et al. BLOOD
- Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia
- (2011) V. Rand et al. BLOOD
- Biology, Risk Stratification, and Therapy of Pediatric Acute Leukemias: An Update
- (2011) Ching-Hon Pui et al. JOURNAL OF CLINICAL ONCOLOGY
- Ebf1orPax5haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia
- (2011) Lynn M. Heltemes-Harris et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Endogenous knockdown of survivin improves chemotherapeutic response in ALL models
- (2011) D J Morrison et al. LEUKEMIA
- Wnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia development
- (2011) T C Luis et al. LEUKEMIA
- Activation of Akt is associated with poor prognosis and chemotherapeutic resistance in pediatric B-precursor acute lymphoblastic leukemia
- (2011) Naoto Morishita et al. PEDIATRIC BLOOD & CANCER
- Targeting MYC dependence in cancer by inhibiting BET bromodomains
- (2011) J. A. Mertz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis
- (2011) I Ahmad et al. Cell Death & Disease
- Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome
- (2010) R. C. Harvey et al. BLOOD
- Selective inhibition of BET bromodomains
- (2010) Panagis Filippakopoulos et al. NATURE
- Histone deacetylase inhibitors as anti-neoplastic agents
- (2009) Nicolas Batty et al. CANCER LETTERS
- BCL9 Promotes Tumor Progression by Conferring Enhanced Proliferative, Metastatic, and Angiogenic Properties to Cancer Cells
- (2009) M. Mani et al. CANCER RESEARCH
- Function, regulation and pathological roles of the Gab/DOS docking proteins
- (2009) Franziska U Wöhrle et al. Cell Communication and Signaling
- A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study
- (2009) Monique L Den Boer et al. LANCET ONCOLOGY
- MEK inhibitors potentiate dexamethasone lethality in acute lymphoblastic leukemia cells through the pro-apoptotic molecule BIM
- (2009) A A Rambal et al. LEUKEMIA
- Deletion ofIKZF1and Prognosis in Acute Lymphoblastic Leukemia
- (2009) Charles G. Mullighan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia
- (2009) A. Yoda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Methylation status of Wnt signaling pathway genes affects the clinical outcome of Philadelphia-positive acute lymphoblastic leukemia
- (2008) Vanesa Martin et al. CANCER SCIENCE
- Histone Deacetylase Inhibitor Panobinostat Induces Clinical Responses with Associated Alterations in Gene Expression Profiles in Cutaneous T-Cell Lymphoma
- (2008) L. Ellis et al. CLINICAL CANCER RESEARCH
- A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis
- (2008) Konstantin Petropoulos et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia
- (2008) K Nebral et al. LEUKEMIA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search