Wnt inhibition leads to improved chemosensitivity in paediatric acute lymphoblastic leukaemia

Wnt pathway contributes to the protection by bone marrow stromal cells of acute lymphoblastic leukemia cells and is a potential therapeutic target

(2013) Yang Yang et al.   CANCER LETTERS

Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia

(2013) E J Gang et al.   ONCOGENE

Inhibition of androgen receptor and  -catenin activity in prostate cancer

(2013) E. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia

(2012) T. Bhatla et al.   BLOOD

Improved Survival for Children and Adolescents With Acute Lymphoblastic Leukemia Between 1990 and 2005: A Report From the Children's Oncology Group

(2012) Stephen P. Hunger et al.   JOURNAL OF CLINICAL ONCOLOGY

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

(2012) Jinghui Zhang et al.   NATURE

Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies

(2011) L. E. Hogan et al.   BLOOD

Endogenous knockdown of survivin improves chemotherapeutic response in ALL models

(2011) D J Morrison et al.   LEUKEMIA

Outcome after first relapse in children with acute lymphoblastic leukemia: A report based on the Dutch Childhood Oncology Group (DCOG) relapse all 98 protocol

(2011) H. van den Berg et al.   PEDIATRIC BLOOD & CANCER

An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway

(2011) F. C. Gonsalves et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Targeting Wnt Signaling: Can We Safely Eradicate Cancer Stem Cells?

(2010) F. Takahashi-Yanaga et al.   CLINICAL CANCER RESEARCH

Identification ofptproas a novel target gene of Wnt signaling and its potential role as a receptor for Wnt

(2010) Minseong Kim et al.   FEBS LETTERS

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α

(2010) Curtis A Thorne et al.   Nature Chemical Biology

Lentiviral Vectors to Probe and Manipulate the Wnt Signaling Pathway

(2010) Christophe Fuerer et al.   PLoS One

The Wnt/ -Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML

(2010) Y. Wang et al.   SCIENCE

Structure–activity relationship studies of small-molecule inhibitors of Wnt response

(2009) Jianming Lu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Targeting the WNT/β-catenin/TCF/LEF1 axis in solid and haematological cancers: Multiplicity of therapeutic options

(2009) Iris Gehrke et al.   EUROPEAN JOURNAL OF CANCER

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Reinduction Platform for Children With First Marrow Relapse of Acute Lymphoblastic Leukemia: A Children's Oncology Group Study

(2008) Elizabeth A. Raetz et al.   JOURNAL OF CLINICAL ONCOLOGY

Factors influencing survival after relapse from acute lymphoblastic leukemia: a Children's Oncology Group study

(2008) K Nguyen et al.   LEUKEMIA