Ebf1orPax5haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia

Identification of Pax5 Target Genes in Early B Cell Differentiation

(2014) C. Pridans et al.   JOURNAL OF IMMUNOLOGY

BTG1 regulates glucocorticoid receptor autoinduction in acute lymphoblastic leukemia

(2010) J. C. van Galen et al.   BLOOD

Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19)

(2010) K. Hirose et al.   BLOOD

How I treat Philadelphia chromosome-positive acute lymphoblastic leukemia

(2010) A. K. Fielding   BLOOD

Stat5 is indispensable for the maintenance ofbcr/abl-positive leukaemia

(2010) Andrea Hoelbl et al.   EMBO Molecular Medicine

The expression of LMO2 protein in acute B-cell and myeloid leukemia

(2010) Umit Cobanoglu et al.   Hematology

Early B Cell Factor 1 Regulates B Cell Gene Networks by Activation, Repression, and Transcription- Independent Poising of Chromatin

(2010) Thomas Treiber et al.   IMMUNITY

BCL6 is critical for the development of a diverse primary B cell repertoire

(2010) Cihangir Duy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia

(2010) Jorge H. Milone et al.   LEUKEMIA & LYMPHOMA

Bcl2 family proteins in carcinogenesis and the treatment of cancer

(2009) Anna Frenzel et al.   APOPTOSIS

Pre–B cell receptor–mediated cell cycle arrest in Philadelphia chromosome–positive acute lymphoblastic leukemia requiresIKAROSfunction

(2009) Daniel Trageser et al.   JOURNAL OF EXPERIMENTAL MEDICINE

RANK-RANKL Signaling Pathway Is Critically Involved in the Function of CD4 + CD25 + Regulatory T Cells in Chronic Colitis

(2009) Teruji Totsuka et al.   JOURNAL OF IMMUNOLOGY

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study

(2009) Monique L Den Boer et al.   LANCET ONCOLOGY

Uncoupling protein-2 and cancer

(2009) Gyorgy Baffy   MITOCHONDRION

Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development

(2009) Stephen Malin et al.   NATURE IMMUNOLOGY

Deletion ofIKZF1and Prognosis in Acute Lymphoblastic Leukemia

(2009) Charles G. Mullighan et al.   NEW ENGLAND JOURNAL OF MEDICINE

JAK mutations in high-risk childhood acute lymphoblastic leukemia

(2009) C. G. Mullighan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BLNK suppresses pre-B-cell leukemogenesis through inhibition of JAK3

(2008) J. Nakayama et al.   BLOOD

Functional proteomic profiling of AML predicts response and survival

(2008) S. M. Kornblau et al.   BLOOD

Instructive Role of the Transcription Factor E2A in Early B Lymphopoiesis and Germinal Center B Cell Development

(2008) Kyongrim Kwon et al.   IMMUNITY

Acute lymphoblastic leukaemia

(2008) Ching-Hon Pui et al.   LANCET

Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros

(2008) Damien Reynaud et al.   NATURE IMMUNOLOGY

Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5

(2008) Jagan M R Pongubala et al.   NATURE IMMUNOLOGY