The Role of cis- and trans-Acting RNA Regulatory Elements in Leukemia

Silencing of lncRNA UCA1 curbs proliferation and accelerates apoptosis by repressing SIRT1 signals by targeting miR‐204 in pediatric AML

(2020) Yu Liang et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Pan-genomics in the human genome era

(2020) Rachel M. Sherman et al.   NATURE REVIEWS GENETICS

Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours

(2020) David S. Hong et al.   BRITISH JOURNAL OF CANCER

Inhibition of RNA-binding protein HuR reduces glomerulosclerosis in experimental nephritis

(2020) Simeng Liu et al.   CLINICAL SCIENCE

RNA-Targeted Therapies and High-Throughput Screening Methods

(2020) Siran Zhu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

LncRNA MAGI2-AS3 inhibits the self-renewal of leukaemic stem cells by promoting TET2-dependent DNA demethylation of the LRIG1 promoter in acute myeloid leukaemia

(2020) Lijuan Chen et al.   RNA Biology

LncRNA LINC00909 promotes cell proliferation and metastasis in pediatric acute myeloid leukemia via miR-625-mediated modulation of Wnt/β-catenin signaling

(2020) Lei Ma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of RNA-binding proteins with small molecules

(2020) Peng Wu   Nature Reviews Chemistry

Circular RNAs in Blood Malignancies

(2020) Olivia Perez de Acha et al.   Frontiers in Molecular Biosciences

LncRNA CDKN2B-AS1 contributes to tumorigenesis and chemoresistance in pediatric T-cell acute lymphoblastic leukemia through miR-335-3p/TRAF5 axis

(2020) Longfeng Chen et al.   ANTI-CANCER DRUGS

A single-cell survey of cellular hierarchy in acute myeloid leukemia

(2020) Junqing Wu et al.   Journal of Hematology & Oncology

Long non‑coding RNA AWPPH interacts with ROCK2 and regulates the proliferation and apoptosis of cancer cells in pediatric T‑cell acute lymphoblastic leukemia

(2020) Xiaohui Li et al.   Oncology Letters

Lnc-SOX6-1 upregulation correlates with poor risk stratification and worse treatment outcomes, and promotes cell proliferation while inhibits apoptosis in pediatric acute myeloid leukemia

(2019) Xianmin Guan et al.   International Journal of Laboratory Hematology

Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity

(2019) Peter van Galen et al.   CELL

Roles of Non-coding RNAs in Human Diseases[Introductory Editorial for the Theme: Roles of non-coding RNAs in Human Diseases]

(2019) Shizuka Uchida et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia

(2019) Shi Hao Tan et al.   BLOOD

Coding or Noncoding, the Converging Concepts of RNAs

(2019) Jing Li et al.   Frontiers in Genetics

Mutations in Spliceosome Genes and Therapeutic Opportunities in Myeloid Malignancies

(2019) Justin Taylor et al.   GENES CHROMOSOMES & CANCER

MicroRNA-206 serves as a tumor suppressor in pediatric acute myeloid leukemia by targeting Cyclin D1

(2019) Hong Liu et al.   PATHOLOGY RESEARCH AND PRACTICE

The role of Xist ‐mediated Polycomb recruitment in the initiation of X‐chromosome inactivation

(2019) Aurélie Bousard et al.   EMBO REPORTS

Endocytic Profiling of Cancer Cell Models Reveals Critical Factors Influencing LNP-Mediated mRNA Delivery and Protein Expression

(2019) Edward J. Sayers et al.   MOLECULAR THERAPY

Long Non-Coding RNAs As Novel Therapeutic Targets in Juvenile Myelomonocytic Leukemia: Proof of Concept Study

(2019) Mattias Hofmans et al.   BLOOD

Naked antisense double-stranded DNA oligonucleotide efficiently suppresses BCR-ABL positive leukemic cells

(2019) Toshimi Hoshiko et al.   INVESTIGATIONAL NEW DRUGS

circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression

(2019) Wei Huang et al.   Journal of Hematology & Oncology

Circulating microRNAs as minimal residual disease biomarkers in childhood acute lymphoblastic leukemia

(2019) Andrea Rzepiel et al.   Journal of Translational Medicine

Retention of CD19 intron 2 contributes to CART-19 resistance in leukemias with subclonal frameshift mutations in CD19

(2019) Mukta Asnani et al.   LEUKEMIA

The U1 spliceosomal RNA is recurrently mutated in multiple cancers

(2019) Shimin Shuai et al.   NATURE

Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk

(2019) Jayaram Vijayakrishnan et al.   Nature Communications

Expression of the long non-coding RNA TCL6 is associated with clinical outcome in pediatric B-cell acute lymphoblastic leukemia

(2019) Marta Cuadros et al.   Blood Cancer Journal

Transcriptome analysis reveals significant differences between primary plasma cell leukemia and multiple myeloma even when sharing a similar genetic background

(2019) Elizabeta A. Rojas et al.   Blood Cancer Journal

Circular RNA differential expression in blood cell populations and exploration of circRNA deregulation in pediatric acute lymphoblastic leukemia

(2019) Enrico Gaffo et al.   Scientific Reports

The Role of MicroRNA in Paediatric Acute Lymphoblastic Leukaemia: Challenges for Diagnosis and Therapy

(2019) Carle Grobbelaar et al.   Journal of Oncology

Chemotherapy-Induced Tumor Cell Death at the Crossroads Between Immunogenicity and Immunotolerance: Focus on Acute Myeloid Leukemia

(2019) Darina Ocadlikova et al.   Frontiers in Oncology

HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice

(2019) Huacheng Luo et al.   CANCER CELL

Comprehensive Characterization of Somatic Mutations Impacting lncRNA Expression for Pan-Cancer

(2019) Yue Gao et al.   Molecular Therapy-Nucleic Acids

Immunotherapy for acute myeloid leukemia (AML): a potent alternative therapy

(2018) Desmond O. Acheampong et al.   BIOMEDICINE & PHARMACOTHERAPY

CTCF boundary remodels chromatin domain and drives aberrant HOX gene transcription in acute myeloid leukemia

(2018) Huacheng Luo et al.   BLOOD

Structure of the human activated spliceosome in three conformational states

(2018) Xiaofeng Zhang et al.   CELL RESEARCH

Circ-ANAPC7 is Upregulated in Acute Myeloid Leukemia and Appears to Target the MiR-181 Family

(2018) Hongli Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The long non-coding RNA landscape in juvenile myelomonocytic leukemia

(2018) Mattias Hofmans et al.   HAEMATOLOGICA

MicroRNAs as New Biomarkers for Diagnosis and Prognosis, and as Potential Therapeutic Targets in Acute Myeloid Leukemia

(2018) Stefania Trino et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Knockdown of LncRNA-UCA1 suppresses chemoresistance of pediatric AML by inhibiting glycolysis through the microRNA-125a/hexokinase 2 pathway

(2018) Yuan Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches

(2018) Nicola Amodio et al.   Journal of Hematology & Oncology

Upregulation of the EMT marker vimentin is associated with poor clinical outcome in acute myeloid leukemia

(2018) Sharon Wu et al.   Journal of Translational Medicine

MYC-containing amplicons in acute myeloid leukemia: genomic structures, evolution, and transcriptional consequences

(2018) Alberto L′Abbate et al.   LEUKEMIA

GATA2 monoallelic expression underlies reduced penetrance in inherited GATA2-mutated MDS/AML

(2018) Ahad F. Al Seraihi et al.   LEUKEMIA

Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia

(2018) Bin Zhang et al.   NATURE MEDICINE

A modular platform for targeted RNAi therapeutics

(2018) Ranit Kedmi et al.   Nature Nanotechnology

A brave new world of RNA-binding proteins

(2018) Matthias W. Hentze et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Circular RNA PVT1 expression and its roles in acute lymphoblastic leukemia

(2018) Jiaojiao Hu et al.   Epigenomics

Systematic Analysis of Splice-Site-Creating Mutations in Cancer

(2018) Reyka G. Jayasinghe et al.   Cell Reports

Targeting RNA in mammalian systems with small molecules

(2018) Anita Donlic et al.   Wiley Interdisciplinary Reviews-RNA

The long non-coding RNA landscape in juvenile myelomonocytic leukemia

(2018) Mattias Hofmans et al.   HAEMATOLOGICA

Tumor Immunity and Survival as a Function of Alternative Neopeptides in Human Cancer

(2018) Andrew J. Rech et al.   Cancer Immunology Research

Open questions: How many genes do we have?

(2018) Steven L. Salzberg   BMC BIOLOGY

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

(2018) André Kahles et al.   CANCER CELL

Long noncoding RNA HOTAIR promotes the self-renewal of leukemia stem cells through epigenetic silencing of p15

(2018) Shenmeng Gao et al.   EXPERIMENTAL HEMATOLOGY

Circular RNA of vimentin expression as a valuable predictor for acute myeloid leukemia development and prognosis

(2018) Yun-Yun Yi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia

(2018) Shih-Han Lee et al.   NATURE

Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia

(2018) Elena J. Orlando et al.   NATURE MEDICINE

Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods

(2018) J. Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Aberrant splicing in B-cell acute lymphoblastic leukemia

(2018) Kathryn L Black et al.   NUCLEIC ACIDS RESEARCH

Bone marrow infiltrated Lnc-INSR induced suppressive immune microenvironment in pediatric acute lymphoblastic leukemia

(2018) Yaping Wang et al.   Cell Death & Disease

LncRNA UCA1 promotes cell proliferation, invasion and migration of laryngeal squamous cell carcinoma cells by activating Wnt/β‑catenin signaling pathway

(2018) Suguang Sun et al.   Experimental and Therapeutic Medicine

Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes

(2018) Nuphar Veiga et al.   Nature Communications

Sequence Determinants for Nuclear Retention and Cytoplasmic Export of mRNAs and lncRNAs

(2018) Alexander F. Palazzo et al.   Frontiers in Genetics

CircPAN3 mediates drug resistance in acute myeloid leukemia through the miR-153-5p/miR-183-5p–XIAP axis

(2018) Jin Shang et al.   EXPERIMENTAL HEMATOLOGY

Non-AUG translation: a new start for protein synthesis in eukaryotes

(2017) Michael G. Kearse et al.   GENES & DEVELOPMENT

Long non-coding RNA expression profile in cytogenetically normal acute myeloid leukemia identifies a distinct signature and a new biomarker in NPM1-mutated patients

(2017) Etienne De Clara et al.   HAEMATOLOGICA

Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia

(2017) Dimitrios Papaioannou et al.   HAEMATOLOGICA

Characterization of hsa_circ_0004277 as a New Biomarker for Acute Myeloid Leukemia via Circular RNA Profile and Bioinformatics Analysis

(2017) Wei Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

5’UTR point substitutions and N-terminal truncating mutations of ANKRD26 in acute myeloid leukemia

(2017) Caterina Marconi et al.   Journal of Hematology & Oncology

CD19 Isoforms Enabling Resistance to CART-19 Immunotherapy Are Expressed in B-ALL Patients at Initial Diagnosis

(2017) Jeannette Fischer et al.   JOURNAL OF IMMUNOTHERAPY

The lncRNA CASC15 regulates SOX4 expression in RUNX1-rearranged acute leukemia

(2017) Thilini R. Fernando et al.   Molecular Cancer

FDA-Approved Oligonucleotide Therapies in 2017

(2017) Cy A. Stein et al.   MOLECULAR THERAPY

Translation from unconventional 5′ start sites drives tumour initiation

(2017) Ataman Sendoel et al.   NATURE

Diversity in non-repetitive human sequences not found in the reference genome

(2017) Birte Kehr et al.   NATURE GENETICS

The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia

(2017) Yu Liu et al.   NATURE GENETICS

The functions and unique features of long intergenic non-coding RNA

(2017) Julia D. Ransohoff et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Complete motif analysis of sequence requirements for translation initiation at non-AUG start codons

(2017) Alexander J Diaz de Arce et al.   NUCLEIC ACIDS RESEARCH

The non-coding RNA landscape of human hematopoiesis and leukemia

(2017) Adrian Schwarzer et al.   Nature Communications

Acute lymphoblastic leukemia: a comprehensive review and 2017 update

(2017) T Terwilliger et al.   Blood Cancer Journal

The Functional Impact of Alternative Splicing in Cancer

(2017) Héctor Climente-González et al.   Cell Reports

Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip

(2017) Madapura M. Pradeepa et al.   PLoS Genetics

Long non-coding RNA expression profile in cytogenetically normal acute myeloid leukemia identifies a distinct signature and a new biomarker in NPM1-mutated patients

(2017) Etienne De Clara et al.   HAEMATOLOGICA

Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia

(2017) Dimitrios Papaioannou et al.   HAEMATOLOGICA

Confirmation of involvement of new variants at CDKN2A/B in pediatric acute lymphoblastic leukemia susceptibility in the Spanish population

(2017) Angela Gutierrez-Camino et al.   PLoS One

RAN translation—What makes it run?

(2016) Katelyn M. Green et al.   BRAIN RESEARCH

Genomics of primary chemoresistance and remission induction failure in paediatric and adult acute myeloid leukaemia

(2016) Fiona C. Brown et al.   BRITISH JOURNAL OF HAEMATOLOGY

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells

(2016) Eric R. Lechman et al.   CANCER CELL

OncomiR or Tumor Suppressor? The Duplicity of MicroRNAs in Cancer

(2016) Alexander A. Svoronos et al.   CANCER RESEARCH

Oncogenic Role of Fusion-circRNAs Derived from Cancer-Associated Chromosomal Translocations

(2016) Jlenia Guarnerio et al.   CELL

The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway

(2016) Zhen-Hua Chen et al.   CELL DEATH AND DIFFERENTIATION

RNA Splicing Modulation Selectively Impairs Leukemia Stem Cell Maintenance in Secondary Human AML

(2016) Leslie A. Crews et al.   Cell Stem Cell

The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non‐coding RNA and synonymous mutations

(2016) Sven Diederichs et al.   EMBO Molecular Medicine

The AS‐RBM15 lncRNA enhances RBM15 protein translation during megakaryocyte differentiation

(2016) Ngoc‐Tung Tran et al.   EMBO REPORTS

LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19

(2016) H. H. Helsmoortel et al.   HAEMATOLOGICA

Aberrant splicing and drug resistance in AML

(2016) Rosalia de Necochea-Campion et al.   Journal of Hematology & Oncology

Functionally distinct roles for different miR-155 expression levels through contrasting effects on gene expression, in acute myeloid leukaemia

(2016) N Narayan et al.   LEUKEMIA

Long Non-Coding RNA CCAT1 Acts as a Competing Endogenous RNA to Regulate Cell Growth and Differentiation in Acute Myeloid Leukemia

(2016)   MOLECULES AND CELLS

Alternative polyadenylation of mRNA precursors

(2016) Bin Tian et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Reciprocal regulation of chromatin state and architecture by HOTAIRM1 contributes to temporal collinear HOXA gene activation

(2016) Xue Q. D. Wang et al.   NUCLEIC ACIDS RESEARCH

Increased complexity of circRNA expression during species evolution

(2016) Rui Dong et al.   RNA Biology

LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19

(2016) H. H. Helsmoortel et al.   HAEMATOLOGICA

Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia

(2016) Yuan-Fang Liu et al.   EBioMedicine

Overexpression and knockout of miR-126 both promote leukemogenesis

(2015) Z. Li et al.   BLOOD

Randomized study of reduced-intensity chemotherapy combined with imatinib in adults with Ph-positive acute lymphoblastic leukemia

(2015) Y. Chalandon et al.   BLOOD

Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers

(2015) Xiaohui Yan et al.   CANCER CELL

Long non-coding RNA HOTAIR modulates c-KIT expression through sponging miR-193a in acute myeloid leukemia

(2015) Chong-yun Xing et al.   FEBS LETTERS

Targeting leukemia stem cells in vivo with antagomiR-126 nanoparticles in acute myeloid leukemia

(2015) A M Dorrance et al.   LEUKEMIA

BALR-6 regulates cell growth and cell survival in B-lymphoblastic leukemia

(2015) Norma I. Rodríguez-Malavé et al.   Molecular Cancer

LncRNA Expression Discriminates Karyotype and Predicts Survival in B-Lymphoblastic Leukemia

(2015) T. R. Fernando et al.   MOLECULAR CANCER RESEARCH

Unknown

(2015) Basile Stamatopoulos et al.   MOLECULAR MEDICINE

Alternative 3′ UTRs act as scaffolds to regulate membrane protein localization

(2015) Binyamin D. Berkovits et al.   NATURE

Non-coding recurrent mutations in chronic lymphocytic leukaemia

(2015) Xose S. Puente et al.   NATURE

Mutations driving CLL and their evolution in progression and relapse

(2015) Dan A. Landau et al.   NATURE

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

(2015) Anna K Andersson et al.   NATURE GENETICS

RNA mis-splicing in disease

(2015) Marina M. Scotti et al.   NATURE REVIEWS GENETICS

SomamiR 2.0: a database of cancer somatic mutations altering microRNA–ceRNA interactions

(2015) Anindya Bhattacharya et al.   NUCLEIC ACIDS RESEARCH

Microarray profiling of bone marrow long non-coding RNA expression in Chinese pediatric acute myeloid leukemia patients

(2015) LAN CAO et al.   ONCOLOGY REPORTS

The functional role of microRNA in acute lymphoblastic leukemia: relevance for diagnosis, differential diagnosis, prognosis, and therapy

(2015) Baoan Chen et al.   OncoTargets and Therapy

Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy

(2015) E. Sotillo et al.   Cancer Discovery

C/EBPα-p30 protein induces expression of the oncogenic long non-coding RNA UCA1 in acute myeloid leukemia

(2015) James M. Hughes et al.   Oncotarget

LncRNA NALT interaction with NOTCH1 promoted cell proliferation in pediatric T cell acute lymphoblastic leukemia

(2015) Yaping Wang et al.   Scientific Reports

siRNA Versus miRNA as Therapeutics for Gene Silencing

(2015) Jenny K W Lam et al.   Molecular Therapy-Nucleic Acids

Genetic variants in microRNA genes: impact on microRNA expression, function, and disease

(2015) Sophia Cammaerts et al.   Frontiers in Genetics

Is miR-29 an oncogene or tumor suppressor in CLL?

(2015)   Oncotarget

Association of Thymidylate Synthase 5'-UTR 28bp Tandem Repeat and Serine Hydroxymethyltransfarase C1420T Polymorphisms with Susceptibility to Acute Leukemia

(2014) Nageswara Rao Dunna et al.   Asian Pacific Journal of Cancer Prevention

Dual mechanisms by which miR-125b represses IRF4 to induce myeloid and B-cell leukemias

(2014) A. Y.-L. So et al.   BLOOD

Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia

(2014) M. Rajasagi et al.   BLOOD

Genome-wide Mapping and Characterization of Notch-Regulated Long Noncoding RNAs in Acute Leukemia

(2014) Thomas Trimarchi et al.   CELL

Role of miR-15/16 in CLL

(2014) Y Pekarsky et al.   CELL DEATH AND DIFFERENTIATION

Repeat associated non-ATG (RAN) translation: new starts in microsatellite expansion disorders

(2014) John Douglas Cleary et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Management of chronic lymphocytic leukemia

(2014) P. Ghia et al.   HAEMATOLOGICA

A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies

(2014) Jingnan Sun et al.   NUCLEIC ACIDS RESEARCH

Expression and prognostic impact of lncRNAs in acute myeloid leukemia

(2014) Ramiro Garzon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long intergenic non-coding RNA HOTAIRM1 regulates cell cycle progression during myeloid maturation in NB4 human promyelocytic leukemia cells

(2014) Xueqing Zhang et al.   RNA Biology

SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy

(2014) N. A. Naryshkin et al.   SCIENCE

Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1)

(2014) J Huang et al.   Cell Death & Disease

Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types

(2014) Zheng Xia et al.   Nature Communications

Therapeutic antisense oligonucleotides against cancer: hurdling to the clinic

(2014) Pedro M. D. Moreno et al.   Frontiers in Chemistry

Acquired copy number alterations of miRNA genes in acute myeloid leukemia are uncommon

(2013) G. Ramsingh et al.   BLOOD

Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia

(2013) E. Diffner et al.   BLOOD

Xist RNA Is a Potent Suppressor of Hematologic Cancer in Mice

(2013) Eda Yildirim et al.   CELL

The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease

(2013) E Mogilyansky et al.   CELL DEATH AND DIFFERENTIATION

Human diseases caused by germline and somatic abnormalities in microRNA and microRNA-related genes

(2013) Yukio Kawahara   CONGENITAL ANOMALIES

First microRNA mimic enters clinic

(2013) Aaron Bouchie   NATURE BIOTECHNOLOGY

Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

(2013) Gaurav Sahay et al.   NATURE BIOTECHNOLOGY

rSNPBase: a database for curated regulatory SNPs

(2013) Liyuan Guo et al.   NUCLEIC ACIDS RESEARCH

Comprehensive Analysis of Single Nucleotide Polymorphisms in Human MicroRNAs

(2013) Miao Han et al.   PLoS One

On the classification of long non-coding RNAs

(2013) Lina Ma et al.   RNA Biology

The Molecular Basis of  -Thalassemia

(2013) S. L. Thein   Cold Spring Harbor Perspectives in Medicine

Gene Expression Regulation by Upstream Open Reading Frames and Human Disease

(2013) Cristina Barbosa et al.   PLoS Genetics

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

(2012) T. Derrien et al.   GENOME RESEARCH

Leukemia-associated antigens and their relevance to the immunotherapy of acute myeloid leukemia

(2012) S Anguille et al.   LEUKEMIA

SomamiR: a database for somatic mutations impacting microRNA function in cancer

(2012) Anindya Bhattacharya et al.   NUCLEIC ACIDS RESEARCH

Oncomir miR-125b regulates hematopoiesis by targeting the gene Lin28A

(2012) A. A. Chaudhuri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ENCODE Project Writes Eulogy for Junk DNA

(2012) E. Pennisi   SCIENCE

Dantrolene Enhances Antisense-Mediated Exon Skipping in Human and Mouse Models of Duchenne Muscular Dystrophy

(2012) G. C. Kendall et al.   Science Translational Medicine

The Human Transcriptome: An Unfinished Story

(2012) Mihaela Pertea   Genes

Mutations in the 5′ UTR of ANKRD26, the Ankirin Repeat Domain 26 Gene, Cause an Autosomal-Dominant Form of Inherited Thrombocytopenia, THC2

(2011) Tommaso Pippucci et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis

(2011) Jing Gong et al.   HUMAN MUTATION

Mechanisms and Consequences of Alternative Polyadenylation

(2011) Dafne Campigli Di Giammartino et al.   MOLECULAR CELL

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

(2011) Kevin C. Wang et al.   NATURE

Correction: 3′UTR-Mediated Gene Silencing of the Mixed Lineage Leukemia (MLL) Gene

(2011) Maria Gomez-Benito et al.   PLoS One

Complete characterization of the microRNAome in a patient with acute myeloid leukemia

(2010) G. Ramsingh et al.   BLOOD

A myelopoiesis-associated regulatory intergenic noncoding RNA transcript within the human HOXA cluster

(2009) X. Zhang et al.   BLOOD

Global Changes in Processing of mRNA 3' Untranslated Regions Characterize Clinically Distinct Cancer Subtypes

(2009) P. Singh et al.   CANCER RESEARCH

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

5-Year Survival in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia in a Randomized, Phase III Trial of Fludarabine Plus Cyclophosphamide With or Without Oblimersen

(2009) Susan O'Brien et al.   JOURNAL OF CLINICAL ONCOLOGY

The pathobiology of splicing

(2009) Amanda J Ward et al.   JOURNAL OF PATHOLOGY

Non-coding RNAs: regulators of disease

(2009) Ryan J Taft et al.   JOURNAL OF PATHOLOGY

Identification of miR-145 and miR-146a as mediators of the 5q– syndrome phenotype

(2009) Daniel T Starczynowski et al.   NATURE MEDICINE

The transcriptome of human CD34+ hematopoietic stem-progenitor cells

(2009) Y. C. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycogen synthase kinase 3  missplicing contributes to leukemia stem cell generation

(2009) A. E. Abrahamsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development

(2009) Z. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element

(2008) A. K. Ebralidze et al.   GENES & DEVELOPMENT

Splicing regulation: From a parts list of regulatory elements to an integrated splicing code

(2008) Z. Wang et al.   RNA

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

(2008) R. Sandberg et al.   SCIENCE

Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia

(2008) C. G. Mullighan et al.   SCIENCE