Leukemia-associated antigens and their relevance to the immunotherapy of acute myeloid leukemia

M-Phase Phosphoprotein 11 Is a Highly Immunogenic Tumor Antigen in Patients with Acute Myeloid Leukemia

(2012) Sandra Siegel et al.   ACTA HAEMATOLOGICA

Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen

(2012) S. Ochsenreither et al.   BLOOD

Active Specific Immunotherapy Targeting the Wilms' Tumor Protein 1 (WT1) for Patients with Hematological Malignancies and Solid Tumors: Lessons from Early Clinical Trials

(2012) A. Van Driessche et al.   ONCOLOGIST

Cancer-testis antigen expression and its epigenetic modulation in acute myeloid leukemia

(2011) Djordje Atanackovic et al.   AMERICAN JOURNAL OF HEMATOLOGY

MUC1-C oncoprotein suppresses reactive oxygen species-induced terminal differentiation of acute myelogenous leukemia cells

(2011) L. Yin et al.   BLOOD

Acute myeloid leukemia with mutated nucleophosmin (NPM1): Any hope for a targeted therapy?

(2011) Brunangelo Falini et al.   BLOOD REVIEWS

Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells

(2011) Lan-Lan Smith et al.   Cell Stem Cell

PRAME-Specific Allo-HLA-Restricted T Cells with Potent Antitumor Reactivity Useful for Therapeutic T-Cell Receptor Gene Transfer

(2011) A. L. Amir et al.   CLINICAL CANCER RESEARCH

Cross-priming of CD8+ T cells in vivo by dendritic cells pulsed with autologous apoptotic leukemic cells in immunotherapy for elderly patients with acute myeloid leukemia

(2011) Toshio Kitawaki et al.   EXPERIMENTAL HEMATOLOGY

Dendritic cell vaccine therapy for acute myeloid leukemia: Questions and answers

(2011) Sébastien Anguille et al.   Human vaccines & immunotherapeutics

Improved outcome following allogeneic stem cell transplantation in chronic myeloid leukemia is associated with higher expression of BMI-1 and immune responses to BMI-1 protein

(2011) A S M Yong et al.   LEUKEMIA

Interferon-α in acute myeloid leukemia: an old drug revisited

(2011) S Anguille et al.   LEUKEMIA

Bmi1 is essential for leukemic reprogramming of myeloid progenitor cells

(2011) J Yuan et al.   LEUKEMIA

Characterization of chronic myeloid leukemia stem cells

(2010) Jonathan M. Gerber et al.   AMERICAN JOURNAL OF HEMATOLOGY

Antibodies specifically target AML antigen NuSAP1 after allogeneic bone marrow transplantation

(2010) P. P. Wadia et al.   BLOOD

Vaccination with synthetic analog peptides derived from WT1 oncoprotein induces T-cell responses in patients with complete remission from acute myeloid leukemia

(2010) P. G. Maslak et al.   BLOOD

Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia

(2010) O. Goodyear et al.   BLOOD

Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials

(2010) D. Grimwade et al.   BLOOD

Graft-versus-Leukemia Antigen CML66 Elicits Coordinated B-Cell and T-Cell Immunity after Donor Lymphocyte Infusion

(2010) W. Zhang et al.   CLINICAL CANCER RESEARCH

Telomere deregulations possess cytogenetic, phenotype, and prognostic specificities in acute leukemias

(2010) Valérie Capraro et al.   EXPERIMENTAL HEMATOLOGY

Molecular mechanisms involved in the progression of myelodysplastic syndrome

(2010) Florian Nolte et al.   Future Oncology

CD8+ T-cell immunity against cancer-testis antigens develops following allogeneic stem cell transplantation and reveals a potential mechanism for the graft-versus-leukemia effect

(2010) A. McLarnon et al.   HAEMATOLOGICA

High-dose RHAMM-R3 peptide vaccination for patients with acute myeloid leukemia, myelodysplastic syndrome and multiple myeloma

(2010) J. Greiner et al.   HAEMATOLOGICA

WT1 (Wilms' Tumor Gene 1): Biology and Cancer Immunotherapy

(2010) H. Sugiyama   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

MHC-restricted fratricide of human lymphocytes expressing survivin-specific transgenic T cell receptors

(2010) Matthias Leisegang et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of HLA-A*0201-presented T-cell epitopes derived from the tumor-associated antigen M-phase phosphoprotein II in patients with acute myeloid leukemia

(2010) S Siegel et al.   LEUKEMIA

The t(6;9) associated DEK/CAN fusion protein targets a population of long-term repopulating hematopoietic stem cells for leukemogenic transformation

(2010) C Oancea et al.   LEUKEMIA

Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination

(2010) V. F. Van Tendeloo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Therapeutic Targets for Quiescent, Chemotherapy-Resistant Human Leukemia Stem Cells

(2010) Y. Saito et al.   Science Translational Medicine

Elevated expression of the leukemia-associated antigen SSX2IP predicts survival in acute myeloid leukemia patients who lack detectable cytogenetic rearrangements

(2009) B. Guinn et al.   BLOOD

The preferentially expressed antigen in melanoma (PRAME) inhibits myeloid differentiation in normal hematopoietic and leukemic progenitor cells

(2009) V. G. Oehler et al.   BLOOD

Repression of BMI1 in normal and leukemic human CD34+ cells impairs self-renewal and induces apoptosis

(2009) A. Rizo et al.   BLOOD

CD8+ T-cell responses to tumor-associated antigens correlate with superior relapse-free survival after allo-SCT

(2009) M Kapp et al.   BONE MARROW TRANSPLANTATION

Identification of a novel epitope derived from CML66 that is recognized by anti-leukaemia cytotoxic T lymphocytes

(2009) Koichiro Suemori et al.   BRITISH JOURNAL OF HAEMATOLOGY

Functional Unresponsiveness and Replicative Senescence of Myeloid Leukemia Antigen-specific CD8+ T Cells After Allogeneic Stem Cell Transplantation

(2009) G. L. Beatty et al.   CLINICAL CANCER RESEARCH

The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research

(2009) M. A. Cheever et al.   CLINICAL CANCER RESEARCH

Efficient Activation of LRH-1–specific CD8+ T-cell Responses From Transplanted Leukemia Patients by Stimulation With P2X5 mRNA-electroporated Dendritic Cells

(2009) Ingrid M. Overes et al.   JOURNAL OF IMMUNOTHERAPY

Short-term cultured, interleukin-15 differentiated dendritic cells have potent immunostimulatory properties

(2009) Sébastien Anguille et al.   Journal of Translational Medicine

PML–RARα initiates leukemia by conferring properties of self-renewal to committed promyelocytic progenitors

(2009) S Wojiski et al.   LEUKEMIA

Characterization of BAX inhibitor-1 as a novel leukemia-associated antigen

(2009) S M Schmidt et al.   LEUKEMIA

Identification of a WT1 protein-derived peptide, WT1187, as a HLA-A*0206-restricted, WT1-specific CTL epitope

(2009) Zheyu Li et al.   MICROBIOLOGY AND IMMUNOLOGY

Immunotherapy of Acute Myeloid Leukemia: Current Approaches

(2009) E. L.J.M. Smits et al.   ONCOLOGIST

Dysregulated gene expression networks in human acute myelogenous leukemia stem cells

(2009) R. Majeti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ex vivo characterization of polyclonal memory CD8+ T-cell responses to PRAME-specific peptides in patients with acute lymphoblastic leukemia and acute and chronic myeloid leukemia

(2008) K. Rezvani et al.   BLOOD

High avidity myeloid leukemia-associated antigen-specific CD8+ T cells preferentially reside in the bone marrow

(2008) J. J. Melenhorst et al.   BLOOD

Aurora-A kinase: a novel target of cellular immunotherapy for leukemia

(2008) T. Ochi et al.   BLOOD

Myeloid leukemic progenitor cells can be specifically targeted by minor histocompatibility antigen LRH-1-reactive cytotoxic T cells

(2008) W. J. Norde et al.   BLOOD

The Wilms' Tumor Antigen Is a Novel Target for Human CD4+ Regulatory T Cells: Implications for Immunotherapy

(2008) C. Lehe et al.   CANCER RESEARCH

Identification of an epitope derived from CML66, a novel tumor-associated antigen expressed broadly in human leukemia, recognized by human leukocyte antigen-A*2402-restricted cytotoxic T lymphocytes

(2008) Koichiro Suemori et al.   CANCER SCIENCE

Leukemia-Associated Antigens Are Critical for the Proliferation of Acute Myeloid Leukemia Cells

(2008) J. Greiner et al.   CLINICAL CANCER RESEARCH

Effects of the aurora kinase inhibitors AZD1152-HQPA and ZM447439 on growth arrest and polyploidy in acute myeloid leukemia cell lines and primary blasts

(2008) E. Walsby et al.   HAEMATOLOGICA