Genomics of primary chemoresistance and remission induction failure in paediatric and adult acute myeloid leukaemia

Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting

(2016) J. He et al.   BLOOD

Genomic Profiling of Pediatric Acute Myeloid Leukemia Reveals a Changing Mutational Landscape from Disease Diagnosis to Relapse

(2016) Jason E. Farrar et al.   CANCER RESEARCH

Inositol polyphosphate 4-phosphatase II (INPP4B) is associated with chemoresistance and poor outcome in AML

(2015) Sewa Rijal et al.   BLOOD

Rapid expansion of preexisting nonleukemic hematopoietic clones frequently follows induction therapy for de novo AML

(2015) T. N. Wong et al.   BLOOD

Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia

(2015) Jeffery M. Klco et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

High expression of myocyte enhancer factor 2C (MEF2C) is associated with adverse-risk features and poor outcome in pediatric acute myeloid leukemia: a report from the Children’s Oncology Group

(2015) George S. Laszlo et al.   Journal of Hematology & Oncology

Isocitrate dehydrogenase 1 and 2 mutations induce BCL-2 dependence in acute myeloid leukemia

(2015) Steven M Chan et al.   NATURE MEDICINE

Pediatric AML: From Biology to Clinical Management

(2015) Jasmijn de Rooij et al.   Journal of Clinical Medicine

Comprehensive analysis of genetic alterations and their prognostic impacts in adult acute myeloid leukemia patients

(2014) R Kihara et al.   LEUKEMIA

SETBP1 mutations occur in 9% of MDS/MPN and in 4% of MPN cases and are strongly associated with atypical CML, monosomy 7, isochromosome i(17)(q10), ASXL1 and CBL mutations

(2013) M Meggendorfer et al.   LEUKEMIA

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

(2012) Jinghui Zhang et al.   NATURE

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

(2012) Li Ding et al.   NATURE

NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern

(2011) I. H. I. M. Hollink et al.   BLOOD

SQSTM1-NUP214: a new gene fusion in adult T-cell acute lymphoblastic leukemia

(2010) P. Gorello et al.   HAEMATOLOGICA