Calming the Storm: Natural Immunosuppressants as Adjuvants to Target the Cytokine Storm in COVID-19

Procalcitonin in patients with severe coronavirus disease 2019 (COVID-19): a meta-analysis

(2020) Giuseppe Lippi et al.   CLINICA CHIMICA ACTA

Understanding SARS-CoV-2-Mediated Inflammatory Responses: From Mechanisms to Potential Therapeutic Tools

(2020) Yajing Fu et al.   VIROLOGICA SINICA

Coronavirus disease 2019 and transplantation: The combination of lopinavir/ritonavir and hydroxychloroquine is responsible for excessive tacrolimus trough level and unfavorable outcome

(2020) Tian Xia et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Probable Molecular Mechanism of Remdesivir for the Treatment of COVID-19: Need to Know More

(2020) Abinit Saha et al.   ARCHIVES OF MEDICAL RESEARCH

Tocilizumab: A Therapeutic Option for the Treatment of Cytokine Storm Syndrome in COVID-19

(2020) Abinit Saha et al.   ARCHIVES OF MEDICAL RESEARCH

Immunomodulatory therapy for the management of severe COVID-19. Beyond the anti-viral therapy: A comprehensive review

(2020) Jaume Alijotas-Reig et al.   AUTOIMMUNITY REVIEWS

COVID-19 infection and rheumatoid arthritis: Faraway, so close!

(2020) Ennio Giulio Favalli et al.   AUTOIMMUNITY REVIEWS

COVID ‐19, pulmonary mast cells, cytokine storms, and beneficial actions of luteolin

(2020) Theoharis C. Theoharides   BIOFACTORS

COVID-19 and its implications for thrombosis and anticoagulation

(2020) Jean Marie Connors et al.   BLOOD

COVID-19 infection: the perspectives on immune responses

(2020) Yufang Shi et al.   CELL DEATH AND DIFFERENTIATION

Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure

(2020) Evangelos J. Giamarellos-Bourboulis et al.   Cell Host & Microbe

Serum IgA, IgM, and IgG responses in COVID-19

(2020) Huan Ma et al.   Cellular & Molecular Immunology

Functional exhaustion of antiviral lymphocytes in COVID-19 patients

(2020) Meijuan Zheng et al.   Cellular & Molecular Immunology

Elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients

(2020) Hong-Yi Zheng et al.   Cellular & Molecular Immunology

Treating COVID-19 with colchicine in community healthcare setting

(2020) Emanuel Della-Torre et al.   CLINICAL IMMUNOLOGY

Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely correlated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients

(2020) Xiaohua Chen et al.   CLINICAL INFECTIOUS DISEASES

Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China

(2020) Chuan Qin et al.   CLINICAL INFECTIOUS DISEASES

Safety considerations for chloroquine and hydroxychloroquine in the treatment of COVID-19

(2020) S. Gevers et al.   CLINICAL MICROBIOLOGY AND INFECTION

COVID-19 cytokine storm: The anger of inflammation

(2020) Mehdi Mahmudpour et al.   CYTOKINE

COVID-19: Pathogenesis, cytokine storm and therapeutic potential of interferons

(2020) Shivraj Hariram Nile et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

(2020) Francesca Coperchini et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Immunology of COVID-19: current state of the science

(2020) Nicolas Vabret et al.   IMMUNITY

JAK Inhibition as a New Treatment Strategy for Patients with COVID-19

(2020) Farhad Seif et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Side effects of ruxolitinib in patients with SARS-CoV-2 infection: Two case reports

(2020) Valeria Gaspari et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Review of the 2019 novel coronavirus (SARS-CoV-2) based on current evidence

(2020) Lisheng Wang et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Cytokine storm and immunomodulatory therapy in COVID-19: Role of chloroquine and anti-IL-6 monoclonal antibodies

(2020) Ming Zhao   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Coronavirus disease 2019 (COVID-19): current status and future perspectives

(2020) Heng Li et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Indomethacin and resveratrol as potential treatment adjuncts for SARS‐CoV‐2/COVID‐19

(2020) Mark A. Marinella   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Association of inflammatory markers with the severity of COVID-19: a meta-analysis

(2020) Furong Zeng et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Use of anakinra in severe COVID-19: a case report

(2020) Giovanni Filocamo et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Characteristics and prognostic factors of disease severity in patients with COVID-19: The Beijing experience

(2020) Ying Sun et al.   JOURNAL OF AUTOIMMUNITY

Andrographolide as a potential inhibitor of SARS-CoV-2 main protease: an in silico approach

(2020) Sukanth Kumar Enmozhi et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

SARS-CoV-2 infection of the liver directly contributes to hepatic impairment in patients with COVID-19

(2020) Yijin Wang et al.   JOURNAL OF HEPATOLOGY

Baricitinib therapy in COVID-19: A pilot study on safety and clinical impact

(2020) Fabrizio Cantini et al.   JOURNAL OF INFECTION

Effect of regular intravenous immunoglobulin therapy on prognosis of severe pneumonia in patients with COVID-19

(2020) Yun Xie et al.   JOURNAL OF INFECTION

COVID‐19: Consider IL6 receptor antagonist for the therapy of cytokine storm syndrome in SARS‐CoV‐2 infected patients

(2020) Chiranjib Chakraborty et al.   JOURNAL OF MEDICAL VIROLOGY

Cyclosporine therapy during the COVID-19 pandemic is not a reason for concern.

(2020) Lidia Rudnicka et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

D‐dimer levels on admission to predict in‐hospital mortality in patients with Covid‐19

(2020) Litao Zhang et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy

(2020) Ning Tang et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The case of Complement activation in COVID-19 multiorgan impact

(2020) Marina Noris et al.   KIDNEY INTERNATIONAL

SARS-CoV-2 and viral sepsis: observations and hypotheses

(2020) Hui Li et al.   LANCET

The potential role of Th17 immune responses in coronavirus immunopathology and vaccine-induced immune enhancement

(2020) Peter J. Hotez et al.   MICROBES AND INFECTION

Harnessing innate immunity to eliminate SARS-CoV-2 and ameliorate COVID-19 disease

(2020) Rachel M. Golonka et al.   PHYSIOLOGICAL GENOMICS

Potential effects of curcumin in the treatment of COVID ‐19 infection

(2020) Fatemeh Zahedipour et al.   PHYTOTHERAPY RESEARCH

Cell entry mechanisms of SARS-CoV-2

(2020) Jian Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclosporine therapy in cytokine storm due to coronavirus disease 2019 (COVID-19)

(2020) Erkan Cure et al.   RHEUMATOLOGY INTERNATIONAL

Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review

(2020) Gaber El-Saber Batiha et al.   Nutrients

Plasma CRP level is positively associated with the severity of COVID-19

(2020) Wei Chen et al.   Annals of Clinical Microbiology and Antimicrobials

The hallmarks of COVID-19 disease

(2020) Daolin Tang et al.   PLoS Pathogens

Pulmonary fibrosis secondary to COVID-19: a call to arms?

(2020) Paolo Spagnolo et al.   Lancet Respiratory Medicine

Novel Coronavirus-Induced NLRP3 Inflammasome Activation: A Potential Drug Target in the Treatment of COVID-19

(2020) Adnan Shah   Frontiers in Immunology

MSC Therapies for COVID-19: Importance of Patient Coagulopathy, Thromboprophylaxis, Cell Product Quality and Mode of Delivery for Treatment Safety and Efficacy

(2020) Guido Moll et al.   Frontiers in Immunology

Coronavirus Disease (COVID-19–SARS-CoV-2) and Nutrition: Is Infection in Italy Suggesting a Connection?

(2020) Hellas Cena et al.   Frontiers in Immunology

Highlight of Immune Pathogenic Response and Hematopathologic Effect in SARS-CoV, MERS-CoV, and SARS-Cov-2 Infection

(2020) Yanwen Liang et al.   Frontiers in Immunology

Could SARS-CoV-2-Induced Hyperinflammation Magnify the Severity of Coronavirus Disease (CoViD-19) Leading to Acute Respiratory Distress Syndrome?

(2020) A. S. Smiline Girija et al.   Frontiers in Immunology

Risk factors for disease progression in hospitalized patients with COVID-19: a retrospective cohort study

(2020) Wei Hou et al.   Infectious Diseases

Impact of immune enhancement on Covid-19 polyclonal hyperimmune globulin therapy and vaccine development

(2020) Ruklanthi de Alwis et al.   EBioMedicine

High-Dose Intravenous Immunoglobulin as a Therapeutic Option for Deteriorating Patients With Coronavirus Disease 2019

(2020) Wei Cao et al.   Open Forum Infectious Diseases

Statin therapy in COVID-19 infection

(2020) Vincenzo Castiglione et al.   European Heart Journal-Cardiovascular Pharmacotherapy

The effect of 6-gingerol on inflammatory response and Th17/Treg balance in DSS-induced ulcerative colitis mice

(2020) Yingyue Sheng et al.   Annals of Translational Medicine

Targeting Cytokine Storm to Manage Patients with COVID-19: A Mini-Review

(2020) Neda Roshanravan et al.   ARCHIVES OF MEDICAL RESEARCH

COVID-19: Immunology and treatment options

(2020) Susanna Felsenstein et al.   CLINICAL IMMUNOLOGY

The first case of COVID-19 treated with the complement C3 inhibitor AMY-101

(2020) Sara Mastaglio et al.   CLINICAL IMMUNOLOGY

The potential of JAK/STAT pathway inhibition by ruxolitinib in the treatment of COVID-19

(2020) Bakiye Goker Bagca et al.   CYTOKINE & GROWTH FACTOR REVIEWS

SARS-Cov-2 infection: Response of human immune system and possible implications for the rapid test and treatment

(2020) di Mauro Gabriella et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Lymphopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A systemic review and meta-analysis

(2020) Qianwen Zhao et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Potential role of statins in COVID-19

(2020) Ken Cheah Hooi Lee et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Eugenol attenuates inflammatory response and enhances barrier function during lipopolysaccharide (LPS)-induced inflammation in the porcine intestinal epithelial (IPEC-J2) cells

(2020) Qianru Hui et al.   JOURNAL OF ANIMAL SCIENCE

Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: A systematic review and meta-analysis

(2020) Leiwen Fu et al.   JOURNAL OF INFECTION

The pathogenesis and treatment of the `Cytokine Storm' in COVID-19

(2020) Qing Ye et al.   JOURNAL OF INFECTION

Clinical characteristics of COVID-19 in 104 people with SARS-CoV-2 infection on the Diamond Princess cruise ship: a retrospective analysis

(2020) Sakiko Tabata et al.   LANCET INFECTIOUS DISEASES

The Janus kinase 1/2 inhibitor ruxolitinib in COVID-19 with severe systemic hyperinflammation

(2020) F. La Rosée et al.   LEUKEMIA

Crosstalk between endoplasmic reticulum stress and anti-viral activities: A novel therapeutic target for COVID-19

(2020) Aditi Banerjee et al.   LIFE SCIENCES

COVID-19 revisiting inflammatory pathways of arthritis

(2020) Georg Schett et al.   Nature Reviews Rheumatology

Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report

(2020)   NEW ENGLAND JOURNAL OF MEDICINE

Cellular immune responses to covid-19

(2020) Herb F Sewell et al.   BMJ-British Medical Journal

Weathering the Cytokine Storm in COVID-19: Therapeutic Implications

(2020) Giulia Iannaccone et al.   CardioRenal Medicine

D-Dimer and Prothrombin Time Are the Significant Indicators of Severe COVID-19 and Poor Prognosis

(2020) Hui Long et al.   Biomed Research International

COVID-19 Is Distinct From SARS-CoV-2-Negative Community-Acquired Pneumonia

(2020) Yutian Zhou et al.   Frontiers in Cellular and Infection Microbiology

Quercetin and Vitamin C: An Experimental, Synergistic Therapy for the Prevention and Treatment of SARS-CoV-2 Related Disease (COVID-19)

(2020) Ruben Manuel Luciano Colunga Biancatelli et al.   Frontiers in Immunology

Targeting the Immune System for Pulmonary Inflammation and Cardiovascular Complications in COVID-19 Patients

(2020) Serena Colafrancesco et al.   Frontiers in Immunology

Cytokine Release Syndrome (CRS) and Nicotine in COVID-19 Patients: Trying to Calm the Storm

(2020) Jesus Gonzalez-Rubio et al.   Frontiers in Immunology

Overview of Immune Response During SARS-CoV-2 Infection: Lessons From the Past

(2020) Vibhuti Kumar Shah et al.   Frontiers in Immunology

Immune Response, Inflammation, and the Clinical Spectrum of COVID-19

(2020) Luis F. García   Frontiers in Immunology

The COVID-19 Cytokine Storm; What We Know So Far

(2020) Dina Ragab et al.   Frontiers in Immunology

COVID-19 coagulopathy: an evolving story

(2020) The Lancet Haematology   Lancet Haematology

Neutrophils, Crucial, or Harmful Immune Cells Involved in Coronavirus Infection: A Bioinformatics Study

(2020) Nima Hemmat et al.   Frontiers in Genetics

COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses

(2020) Muhammad Adnan Shereen et al.   Journal of Advanced Research

The Inhibitory Effect of Curcumin on Virus-Induced Cytokine Storm and Its Potential Use in the Associated Severe Pneumonia

(2020) Ziteng Liu et al.   Frontiers in Cell and Developmental Biology

Evaluation of Current Therapies for COVID-19 Treatment

(2020) Atin Sethi et al.   Microorganisms

Cytokine storm induced by SARS-CoV-2

(2020) Peipei Song et al.   CLINICA CHIMICA ACTA

The enzymatic poly(gallic acid) reduces pro-inflammatory cytokines in vitro, a potential application in inflammatory diseases

(2020) Yessica Zamudio-Cuevas et al.   INFLAMMATION

Inflammation Triggered by SARS-CoV-2 and ACE2 Augment Drives Multiple Organ Failure of Severe COVID-19: Molecular Mechanisms and Implications

(2020) Masae Iwasaki et al.   INFLAMMATION

Protective effect of piperine from Piper chaba fruits on LPS-induced inflammation in human intestinal cell line

(2020) Buagaew Anyanee et al.   Journal of Medicinal Plants Research

SARS-CoV-2 immunity: review and applications to phase 3 vaccine candidates

(2020) Gregory A Poland et al.   LANCET

The immune system and COVID-19: Friend or foe?

(2020) Fereshteh Yazdanpanah et al.   LIFE SCIENCES

A dynamic COVID-19 immune signature includes associations with poor prognosis

(2020) Adam G. Laing et al.   NATURE MEDICINE

Curcumin (a constituent of turmeric): New treatment option against COVID‐19

(2020) Fatemeh Babaei et al.   Food Science & Nutrition

Nano-curcumin therapy, a promising method in modulating inflammatory cytokines in COVID-19 patients

(2020) Hamed Valizadeh et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Colchicine: A potential therapeutic tool against COVID-19. Experience of 5 patients

(2020) Giovanni Montealegre-Gómez et al.   Reumatologia Clinica

Acute respiratory distress syndrome

(2019) Michael A. Matthay et al.   Nature Reviews Disease Primers

Melatonin as a master regulator of cell death and inflammation: molecular mechanisms and clinical implications for newborn care

(2019) Anna Tarocco et al.   Cell Death & Disease

Influence of Resveratrol on the Immune Response

(2019) Malaguarnera   Nutrients

Quercetin Inhibits the Production of IL-1β-Induced Inflammatory Cytokines and Chemokines in ARPE-19 Cells via the MAPK and NF-κB Signaling Pathways

(2019) Shu-Chen Cheng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Melatonin in Medicinal and Food Plants: Occurrence, Bioavailability, and Health Potential for Humans

(2019) Bahare Salehi et al.   Cells

A review for the neuroprotective effects of andrographolide in the central nervous system

(2019) Jiashu Lu et al.   BIOMEDICINE & PHARMACOTHERAPY

Quercetin and Quercitrin Attenuates the Inflammatory Response and Oxidative Stress in LPS-Induced RAW264.7 Cells: In Vitro Assessment and a Theoretical Model

(2019) Jie Tang et al.   Biomed Research International

Therapeutic Potential of Allicin-Rich Garlic Preparations: Emphasis on Clinical Evidence toward Upcoming Drugs Formulation

(2019) Javad Sharifi-Rad et al.   Applied Sciences-Basel

Immunomodulatory properties of quercetin-3-O-α-L-rhamnopyranoside from Rapanea melanophloeos against influenza a virus

(2018) Parvaneh Mehrbod et al.   BMC Complementary and Alternative Medicine

Effect of Resveratrol Dry Suspension on Immune Function of Piglets

(2018) Qiuting Fu et al.   Evidence-based Complementary and Alternative Medicine

Withaferin A Associated Differential Regulation of Inflammatory Cytokines

(2018) Seema Dubey et al.   Frontiers in Immunology

Cytokine release syndrome

(2018) Alexander Shimabukuro-Vornhagen et al.   Journal for ImmunoTherapy of Cancer

6-Gingerol attenuates LPS-induced neuroinflammation and cognitive impairment partially via suppressing astrocyte overactivation

(2018) Feng Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Kaempferol inhibits multiple pathways involved in the secretion of inflammatory mediators from LPS‑induced rat intestinal microvascular endothelial cells

(2018) Yifei Bian et al.   Molecular Medicine Reports

Eugenol as a Promising Molecule for the Treatment of Dermatitis: Antioxidant and Anti-inflammatory Activities and Its Nanoformulation

(2018) Amanda de Araújo Lopes et al.   Oxidative Medicine and Cellular Longevity

An Overview on the Anti-inflammatory Potential and Antioxidant Profile of Eugenol

(2018) Joice Nascimento Barboza et al.   Oxidative Medicine and Cellular Longevity

Black pepper and its bioactive constituent piperine: promising therapeutic strategies for oral lichen planus

(2018) Jing-Ya Yang et al.   INFLAMMOPHARMACOLOGY

Gallic acid improved inflammation via NF-κB pathway in TNBS-induced ulcerative colitis

(2018) Lei Zhu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Andrographolide Inhibits Inflammatory Cytokines Secretion in LPS-Stimulated RAW264.7 Cells through Suppression of NF-κB/MAPK Signaling Pathway

(2017) Yu Li et al.   Evidence-based Complementary and Alternative Medicine

Melatonin alleviates cadmium-induced liver injury by inhibiting the TXNIP-NLRP3 inflammasome

(2017) Zhengwang Cao et al.   JOURNAL OF PINEAL RESEARCH

Anti-inflammatory activity of resveratrol prevents inflammation by inhibiting NF‑κB in animal models of acute pharyngitis

(2017) Zhong‑Xin Zhou et al.   Molecular Medicine Reports

Plants of the Genus Zingiber as a Source of Bioactive Phytochemicals: From Tradition to Pharmacy

(2017) Mehdi Sharifi-Rad et al.   MOLECULES

Essential oil eugenol: sources, extraction techniques and nutraceutical perspectives

(2017) Anees Ahmed Khalil et al.   RSC Advances

Attenuation of Innate Immunity by Andrographolide Derivatives Through NF-κB Signaling Pathway

(2017) Xin Nie et al.   Scientific Reports

Piperine-The Bioactive Compound of Black Pepper: From Isolation to Medicinal Formulations

(2016) Leila Gorgani et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Piperine Plays an Anti-Inflammatory Role inStaphylococcus aureusEndometritis by Inhibiting Activation of NF-κB and MAPK Pathways in Mice

(2016) Wen-jun Zhai et al.   Evidence-based Complementary and Alternative Medicine

Downregulation of proinflammatory cytokines in HTLV-1-infected T cells by Resveratrol

(2016) Maria Pia Fuggetta et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Andrographolide attenuates LPS-stimulated up-regulation of C-C and C-X-C motif chemokines in rodent cortex and primary astrocytes

(2016) Siew Ying Wong et al.   Journal of Neuroinflammation

Anti‐Inflammatory Effect of Quercetin on RAW 264.7 Mouse Macrophages Induced with Polyinosinic‐Polycytidylic Acid

(2016) Young‐Jin Kim et al.   MOLECULES

6-Gingerol inhibitsVibriocholerae-induced proinflammatory cytokines in intestinal epithelial cells via modulation of NF-κB

(2016) Pallashri Saha et al.   PHARMACEUTICAL BIOLOGY

Impact of the Timing of Morphine Administration on Lipopolysaccharide-Mediated Lethal Endotoxic Shock in Mice

(2016) Tomoko Fukada et al.   SHOCK

Quercetin, Inflammation and Immunity

(2016) Yao Li et al.   Nutrients

Melatonin: Current Status and Future Perspectives in Plant Science

(2016) Muhammad A. Nawaz et al.   Frontiers in Plant Science

Piperine Suppresses Pyroptosis and Interleukin-1β Release upon ATP Triggering and Bacterial Infection

(2016) Yi-Dan Liang et al.   Frontiers in Pharmacology

Anti-inflammatory effects of luteolin and luteoloside from Taraxacum coreanum in RAW264.7 macrophage cells

(2016) Ah Young Lee et al.   Applied Biological Chemistry

Gallic Acid Decreases Inflammatory Cytokine Secretion Through Histone Acetyltransferase/Histone Deacetylase Regulation in High Glucose-Induced Human Monocytes

(2015) Wooje Lee et al.   JOURNAL OF MEDICINAL FOOD

Ginsenoside Rb1 Treatment Attenuates Pulmonary Inflammatory Cytokine Release and Tissue Injury following Intestinal Ischemia Reperfusion Injury in Mice

(2015) Ying Jiang et al.   Oxidative Medicine and Cellular Longevity

Citral alleviates an accelerated and severe lupus nephritis model by inhibiting the activation signal of NLRP3 inflammasome and enhancing Nrf2 activation

(2015) Shuk-Man Ka et al.   ARTHRITIS RESEARCH & THERAPY

6-Gingerol modulates proinflammatory responses in dextran sodium sulfate (DSS)-treated Caco-2 cells and experimental colitis in mice through adenosine monophosphate-activated protein kinase (AMPK) activation

(2015) Kuei-Wen Chang et al.   Food & Function

Colchicine Acutely Suppresses Local Cardiac Production of Inflammatory Cytokines in Patients With an Acute Coronary Syndrome

(2015) Gonzalo J. Martínez et al.   Journal of the American Heart Association

Obesity and inflammation: reduced cytokine expression due to resveratrol in a human in vitro model of inflamed adipose tissue

(2015) Ivana Zagotta et al.   Frontiers in Pharmacology

Immunomodulation and Anti-Inflammatory Effects of Garlic Compounds

(2015) Rodrigo Arreola et al.   Journal of Immunology Research

Resveratrol Inhibits Enterovirus 71 Replication and Pro-Inflammatory Cytokine Secretion in Rhabdosarcoma Cells through Blocking IKKs/NF-κB Signaling Pathway

(2015) Li Zhang et al.   PLoS One

Flavonoids Inhibit COX-1 and COX-2 Enzymes and Cytokine/Chemokine Production in Human Whole Blood

(2014) Daniela Ribeiro et al.   INFLAMMATION

Immunomodulatory effects of clove (Syzygium aromaticum) constituents on macrophages:In vitroevaluations of aqueous and ethanolic components

(2014) Shaghayegh Pishkhan Dibazar et al.   Journal of Immunotoxicology

Cytokines and Disease

(2014) Arkadiusz Orzechowski et al.   MEDIATORS OF INFLAMMATION

Citral and eugenol modulate DNA damage and pro-inflammatory mediator genes in murine peritoneal macrophages

(2014) Marilia de Paula Porto et al.   MOLECULAR BIOLOGY REPORTS

Allicin: Chemistry and Biological Properties

(2014) Jan Borlinghaus et al.   MOLECULES

Luteolin Inhibits Hyperglycemia-Induced Proinflammatory Cytokine Production and Its Epigenetic Mechanism in Human Monocytes

(2014) Hye Joo Kim et al.   PHYTOTHERAPY RESEARCH

Luteolin Inhibits Human Keratinocyte Activation and Decreases NF-κB Induction That Is Increased in Psoriatic Skin

(2014) Zuyi Weng et al.   PLoS One

Macrophage Cytokines: Involvement in Immunity and Infectious Diseases

(2014) Guillermo Arango Duque et al.   Frontiers in Immunology

Hydroxychloroquine decreases Th17-related cytokines in systemic lupus erythematosus and rheumatoid arthritis patients

(2013) JC Silva et al.   Clinics

Withaferin A inhibits pro-inflammatory cytokine-induced damage to islets in culture and following transplantation

(2013) J. A. SoRelle et al.   DIABETOLOGIA

Experimental and Clinical Pharmacology ofAndrographis paniculataand Its Major Bioactive Phytoconstituent Andrographolide

(2013) Thanasekaran Jayakumar et al.   Evidence-based Complementary and Alternative Medicine

Attenuation of Proinflammatory Responses byS-[6]-Gingerol via Inhibition of ROS/NF-Kappa B/COX2 Activation in HuH7 Cells

(2013) Xiao-Hong Li et al.   Evidence-based Complementary and Alternative Medicine

Multiple anti-inflammatory pathways triggered by resveratrol lead to amelioration of staphylococcal enterotoxin B-induced lung injury

(2012) Sadiye Amcaoglu Rieder et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effect of resveratrol and modulation of cytokine production on human periodontal ligament cells

(2012) Antonietta Rizzo et al.   CYTOKINE

Clove and eugenol in noncytotoxic concentrations exert immunomodulatory/anti-inflammatory action on cytokine production by murine macrophages

(2012) Tatiana Fernanda Bachiega et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Into the Eye of the Cytokine Storm

(2012) J. R. Tisoncik et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Lemongrass and citral effect on cytokines production by murine macrophages

(2011) Tatiana Fernanda Bachiega et al.   JOURNAL OF ETHNOPHARMACOLOGY

Melatonin suppresses acrolein-induced IL-8 production in human pulmonary fibroblasts

(2011) Gun-Dong Kim et al.   JOURNAL OF PINEAL RESEARCH

Inhibitory effects of melatonin on the lipopolysaccharide-induced CC chemokine expression in BV2 murine microglial cells are mediated by suppression of Akt-induced NF-κB and STAT/GAS activity

(2011) Kyoung-Jin Min et al.   JOURNAL OF PINEAL RESEARCH

Anti-inflammatory effects of nicotine in obesity and ulcerative colitis

(2011) Shaheen E Lakhan et al.   Journal of Translational Medicine

Immunomodulatory activity of andrographolide on macrophage activation and specific antibody response

(2010) Wei Wang et al.   ACTA PHARMACOLOGICA SINICA

Morphine decreases early peritoneal innate immunity responses in Swiss–Webster and C57BL6/J mice through the inhibition of mast cell TNF-α release

(2010) Iris K. Madera-Salcedo et al.   JOURNAL OF NEUROIMMUNOLOGY

Luteolin inhibits cytokine expression in endotoxin/cytokine-stimulated microglia

(2010) Tsung-Kuei Kao et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Luteolin Isolated from the Flowers of Lonicera japonica Suppresses Inflammatory Mediator Release by Blocking NF-κB and MAPKs Activation Pathways in HMC-1 Cells

(2010) Ok-Hwa Kang et al.   MOLECULES

Nicotine and inflammatory neurological disorders

(2009) Wen-Hua Piao et al.   ACTA PHARMACOLOGICA SINICA

Andrographolide: A New Plant-Derived Antineoplastic Entity on Horizon

(2009) Astha Varma et al.   Evidence-based Complementary and Alternative Medicine

Piperine inhibits eosinophil infiltration and airway hyperresponsiveness by suppressing T cell activity and Th2 cytokine production in the ovalbumin-induced asthma model

(2009) Seung-Hyung Kim et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Investigation of antioxidant, anti-inflammatory and DNA-protective properties of eugenol in thioacetamide-induced liver injury in rats

(2009) Baskaran Yogalakshmi et al.   TOXICOLOGY

Curcumin Supplementation Lowers TNF-α, IL-6, IL-8, and MCP-1 Secretion in High Glucose-Treated Cultured Monocytes and Blood Levels of TNF-α, IL-6, MCP-1, Glucose, and Glycosylated Hemoglobin in Diabetic Rats

(2008) Sushil K. Jain et al.   ANTIOXIDANTS & REDOX SIGNALING

Luteolin, a Flavonoid with Potential for Cancer Prevention and Therapy

(2008) Yong Lin et al.   CURRENT CANCER DRUG TARGETS

Andrographolide reduces IL-2 production in T-cells by interfering with NFAT and MAPK activation

(2008) María D. Carretta et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1

(2008) S. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA