Immunomodulation and Anti-Inflammatory Effects of Garlic Compounds

Allicin prevents H2O2-induced apoptosis of HUVECs by inhibiting an oxidative stress pathway

(2014) Sisi Chen et al.   BMC Complementary and Alternative Medicine

The Protective Effect of Aged Garlic Extract on Nonsteroidal Anti-Inflammatory Drug-Induced Gastric Inflammations in Male Albino Rats

(2014) Gehan Moustafa Badr et al.   Evidence-based Complementary and Alternative Medicine

Role of JNK Activation and Mitochondrial Bax Translocation in Allicin-Induced Apoptosis in Human Ovarian Cancer SKOV3 Cells

(2014) Ling Xu et al.   Evidence-based Complementary and Alternative Medicine

Ethyl linoleate from garlic attenuates lipopolysaccharide-induced pro-inflammatory cytokine production by inducing heme oxygenase-1 in RAW264.7 cells

(2014) Sun Young Park et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

DADS Suppresses Human Esophageal Xenograft Tumors through RAF/MEK/ERK and Mitochondria-Dependent Pathways

(2014) Xiaoran Yin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The effects of diallyl sulfide uponPorphyromonas gingivalislipopolysaccharide stimulated proinflammatory cytokine expressions and nuclear factor-kappa B activation in human gingival fibroblasts

(2014) E. Fu et al.   JOURNAL OF PERIODONTAL RESEARCH

Diallyl sulfide as a potential dietary agent to reduce TNF-α- and histamine-induced proinflammatory responses in A7r5 cells

(2014) Cheng-Ying Ho et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Induction of apoptosis by a hexane extract of aged black garlic in the human leukemic U937 cells

(2014) Cheol Park et al.   Nutrition Research and Practice

Allicin enhances chemotherapeutic response and ameliorates tamoxifen-induced liver injury in experimental animals

(2014) Ghada M. Suddek   PHARMACEUTICAL BIOLOGY

Efficacy of garlic based treatments against monogenean parasites infecting the guppy (Poecilia reticulata (Peters))

(2014) S. Fridman et al.   VETERINARY PARASITOLOGY

Chemopreventive functions and molecular mechanisms of garlic organosulfur compounds

(2014) Phoebe Zapanta Trio et al.   Food & Function

IL-10: Master Switch from Tumor-Promoting Inflammation to Antitumor Immunity

(2014) M. Oft   Cancer Immunology Research

S-allylcysteine, a garlic derivative, suppresses proliferation and induces apoptosis in human ovarian cancer cells in vitro

(2013) Ya-si Xu et al.   ACTA PHARMACOLOGICA SINICA

Enhancement of Intestinal IgA Production by Ajoene in Mice

(2013) Yuki WASHIYA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Garlic and cardioprotection: insights into the molecular mechanisms

(2013) Tarak Nath Khatua et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Immunological Properties of Inulin-Type Fructans

(2013) Leonie Vogt et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Diallyl trisulfide-induced apoptosis of bladder cancer cells is caspase-dependent and regulated by PI3K/Akt and JNK pathways

(2013) Dong Yeok Shin et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Diallyl-disulfide, an organosulfur compound of garlic, attenuates airway inflammation via activation of the Nrf-2/HO-1 pathway and NF-kappaB suppression

(2013) In-Sik Shin et al.   FOOD AND CHEMICAL TOXICOLOGY

Allium sativum-derived allitridin inhibits treg amplification in cytomegalovirus infection

(2013) Ya-nan Li et al.   JOURNAL OF MEDICAL VIROLOGY

Alliin, a Garlic (Allium sativum) Compound, Prevents LPS-Induced Inflammation in 3T3-L1 Adipocytes

(2013) Saray Quintero-Fabián et al.   MEDIATORS OF INFLAMMATION

Inhibitory effects and molecular mechanisms of garlic organosulfur compounds on the production of inflammatory mediators

(2013) Sixiang You et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Effect of Allium sativum and Allium cepa oils on different stages of Boophilus annulatus

(2013) S. M. Aboelhadid et al.   PARASITOLOGY RESEARCH

Anti-Wrinkle and Anti-Inflammatory Effects of Active Garlic Components and the Inhibition of MMPs via NF-κB Signaling

(2013) So Ra Kim et al.   PLoS One

Nutritional Recommendations for Cardiovascular Disease Prevention

(2013) Sigal Eilat-Adar et al.   Nutrients

Supplementation with aged garlic extract improves both NK and γδ-T cell function and reduces the severity of cold and flu symptoms: A randomized, double-blind, placebo-controlled nutrition intervention

(2012) Meri P. Nantz et al.   CLINICAL NUTRITION

Aged garlic extract reduces blood pressure in hypertensives: a dose–response trial

(2012) K Ried et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Allicin enhances host pro-inflammatory immune responses and protects against acute murine malaria infection

(2012) Yonghui Feng et al.   MALARIA JOURNAL

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Evaluation of the immunomodulatory effect of the 14kDa protein isolated from aged garlic extract on dendritic cells

(2011) Hasan Namdar Ahmadabad et al.   CELLULAR IMMUNOLOGY

Aged garlic extract inhibits homocysteine-induced scavenger receptor CD36 expression and oxidized low-density lipoprotein cholesterol uptake in human macrophages in vitro

(2011) Naoaki Morihara et al.   JOURNAL OF ETHNOPHARMACOLOGY

Modulatory effects of two levels of dietary Alliums on immune response and certain immunological variables, following immunization, in White Leghorn chickens

(2010) Hamza HANIEH et al.   ANIMAL SCIENCE JOURNAL

From endothelial dysfunction to atherosclerosis

(2010) S. Sitia et al.   AUTOIMMUNITY REVIEWS

Dietary garlic (Allium sativum) lectins, ASA I and ASA II, are highly stable and immunogenic

(2010) Fatima Clement et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Effects of Garlic Oil on the Migration of Neutrophil-Like Cell Studied by Using a Chemotactic Gradient Labchip

(2010) Po-Chen Shih et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Allicin protects against cardiac hypertrophy and fibrosis via attenuating reactive oxygen species-dependent signaling pathways

(2010) Chen Liu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Aged garlic extract lowers blood pressure in patients with treated but uncontrolled hypertension: A randomised controlled trial

(2010) Karin Ried et al.   MATURITAS

Isolation, structural elucidation and immunomodulatory activity of fructans from aged garlic extract

(2010) Puthanapura M. Chandrashekar et al.   PHYTOCHEMISTRY

Chloroform extract of aged black garlic attenuates TNF-α-induced ROS generation, VCAM-1 expression, NF-κB activation and adhesiveness for monocytes in human umbilical vein endothelial cells

(2010) Eun Na Lee et al.   PHYTOTHERAPY RESEARCH

Natural Killer T Cells Are Involved in Adipose Tissues Inflammation and Glucose Intolerance in Diet-Induced Obese Mice

(2009) Kazue Ohmura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Identity of the immunomodulatory proteins from garlic (Allium sativum) with the major garlic lectins or agglutinins

(2009) Fatima Clement et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Identification of the protein components displaying immunomodulatory activity in aged garlic extract

(2009) P.M. Chandrashekar et al.   JOURNAL OF ETHNOPHARMACOLOGY

1,2-Vinyldithiin from Garlic Inhibits Differentiation and Inflammation of Human Preadipocytes

(2009) Mayoura Keophiphath et al.   JOURNAL OF NUTRITION

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

(2009) Jian Liu et al.   NATURE MEDICINE

The impact of garlic on lipid parameters: a systematic review and meta-analysis

(2009) Kurt M. Reinhart et al.   NUTRITION RESEARCH REVIEWS

Effect of Supplementation with Garlic Oil on Activity of Th1 and Th2 Lymphocytes from Rats

(2009) Cheng-Tzu Liu et al.   PLANTA MEDICA

Aged garlic extract supplemented with B vitamins, folic acid and l-arginine retards the progression of subclinical atherosclerosis: A randomized clinical trial

(2009) Matthew J. Budoff et al.   PREVENTIVE MEDICINE

Garlic intake and cancer risk: an analysis using the Food and Drug Administration’s evidence-based review system for the scientific evaluation of health claims

(2008) Ji Yeon Kim et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Effects of Garlic on Blood Pressure in Patients with and Without Systolic Hypertension: A Meta-Analysis

(2008) Kurt M Reinhart et al.   ANNALS OF PHARMACOTHERAPY