The interesting relationship between APOBEC3 deoxycytidine deaminases and cancer: a long road ahead

APOBEC3B expression in breast cancer cell lines and tumors depends on the estrogen receptor status

(2020) Krizia-Ivana Udquim et al.   CARCINOGENESIS

The DNA cytosine deaminase APOBEC3B is a molecular determinant of platinum responsiveness in clear cell ovarian cancer

(2020) Reuben S. Harris et al.   CLINICAL CANCER RESEARCH

HPV induction of APOBEC3 enzymes mediate overall survival and response to cisplatin in head and neck cancer

(2020) Kayla L. Conner et al.   DNA REPAIR

The repertoire of mutational signatures in human cancer

(2020) Ludmil B. Alexandrov et al.   NATURE

Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G

(2020) Hanjing Yang et al.   Nature Communications

Mutations in the HPV16 genome induced by APOBEC3 are associated with viral clearance

(2020) Bin Zhu et al.   Nature Communications

Molecular Origins of APOBEC-Associated Mutations in Cancer

(2020) Mia Petljak et al.   DNA REPAIR

Hypermutation in single-stranded DNA

(2020) Natalie Saini et al.   DNA REPAIR

Quantification of ongoing APOBEC3A activity in tumor cells by monitoring RNA editing at hotspots

(2020) Pégah Jalili et al.   Nature Communications

APOBEC3A catalyzes mutation and drives carcinogenesis in vivo

(2020) Emily K. Law et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pan-cancer transcriptomic analysis dissects immune and proliferative functions of APOBEC3 cytidine deaminases

(2019) Joseph C F Ng et al.   NUCLEIC ACIDS RESEARCH

APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma

(2019) Vincent L. Cannataro et al.   ONCOGENE

The APOBEC3 genes and their role in cancer: insights from human papillomavirus

(2019) Nicola J Smith et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis

(2019) Mia Petljak et al.   CELL

Passenger hotspot mutations in cancer driven by APOBEC3A and mesoscale genomic features

(2019) Rémi Buisson et al.   SCIENCE

Integrative genomic analyses of APOBEC-mutational signature, expression and germline deletion of APOBEC3 genes, and immunogenicity in multiple cancer types

(2019) Zhishan Chen et al.   BMC Medical Genomics

Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

(2019) Cynthia J. Sakofsky et al.   PLOS BIOLOGY

The spectrum of APOBEC3 activity: From anti-viral agents to anti-cancer opportunities

(2019) Abby M. Green et al.   DNA REPAIR

APOBEC3-Mediated RNA Editing in Breast Cancer is Associated with Heightened Immune Activity and Improved Survival

(2019) Mariko Asaoka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

APOBEC3A is a prominent cytidine deaminase in breast cancer

(2019) Luis M. Cortez et al.   PLoS Genetics

Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis

(2019) Marc Arbyn et al.   Lancet Global Health

Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like family genes activation and regulation during tumorigenesis

(2018) Jianlong Gao et al.   CANCER SCIENCE

Presence of Human Papillomavirus (HPV) Apolipoprotein B Messenger RNA Editing, Catalytic Polypeptide-Like 3 (APOBEC)–Related Minority Variants in HPV-16 Genomes From Anal and Cervical Samples but Not in HPV-52 and HPV-58

(2018) Alice-Andrée Mariaggi et al.   JOURNAL OF INFECTIOUS DISEASES

Human Papillomavirus 16 E7 Stabilizes APOBEC3A Protein by Inhibiting Cullin 2-Dependent Protein Degradation

(2018) Joseph A. Westrich et al.   JOURNAL OF VIROLOGY

The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism

(2018) Nadine M. Shaban et al.   MOLECULAR CELL

APOBEC3B and APOBEC mutational signature as potential predictive markers for immunotherapy response in non-small cell lung cancer

(2018) Shixiang Wang et al.   ONCOGENE

Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA

(2018) Atanu Maiti et al.   Nature Communications

Substrate sequence selectivity of APOBEC3A implicates intra-DNA interactions

(2018) Tania V. Silvas et al.   Scientific Reports

Understanding the Structure, Multimerization, Subcellular Localization and mC Selectivity of a Genomic Mutator and Anti-HIV Factor APOBEC3H

(2018) Fumiaki Ito et al.   Scientific Reports

APOBEC3-mediated restriction of RNA virus replication

(2018) Aleksandra Milewska et al.   Scientific Reports

The curious case of APOBEC3 activation by cancer-associated human papillomaviruses

(2018) Nicholas A. Wallace et al.   PLoS Pathogens

Biochemical Basis of APOBEC3 Deoxycytidine Deaminase Activity on Diverse DNA Substrates

(2018) Madison B. Adolph et al.   ACS Infectious Diseases

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016

(2018) et al.   JAMA Oncology

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

DNArCdb: A database of cancer biomarkers in DNA repair genes that includes variants related to multiple cancer phenotypes

(2018) Pavel Silvestrov et al.   DNA REPAIR

Expressed HNSCC variants by HPV-status in a well-characterized Michigan cohort

(2018) Tingting Qin et al.   Scientific Reports

Human papillomavirus and the landscape of secondary genetic alterations in oral cancers

(2018) Maura L. Gillison et al.   GENOME RESEARCH

RNA-Mediated Dimerization of the Human Deoxycytidine Deaminase APOBEC3H Influences Enzyme Activity and Interaction with Nucleic Acids

(2018) Yuqing Feng et al.   JOURNAL OF MOLECULAR BIOLOGY

Epstein–Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity

(2018) Adam Z. Cheng et al.   Nature Microbiology

Family-Wide Comparative Analysis of Cytidine and Methylcytidine Deamination by Eleven Human APOBEC Proteins

(2017) Fumiaki Ito et al.   JOURNAL OF MOLECULAR BIOLOGY

Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription Factor

(2017) Seiichiro Mori et al.   JOURNAL OF VIROLOGY

The Cytidine Deaminase APOBEC3 Family Is Subject to Transcriptional Regulation by p53

(2017) Daniel Menendez et al.   MOLECULAR CANCER RESEARCH

Enzyme cycling contributes to efficient induction of genome mutagenesis by the cytidine deaminase APOBEC3B

(2017) Madison B. Adolph et al.   NUCLEIC ACIDS RESEARCH

p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells

(2017) Manikandan Periyasamy et al.   NUCLEIC ACIDS RESEARCH

Landscape of immunogenic tumor antigens in successful immunotherapy of virally induced epithelial cancer

(2017) Sanja Stevanović et al.   SCIENCE

Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression

(2017) Cody Warren et al.   Viruses-Basel

Modulation of microRNA-mRNA Target Pairs by Human Papillomavirus 16 Oncoproteins

(2017) Mallory E. Harden et al.   mBio

APOBEC3H structure reveals an unusual mechanism of interaction with duplex RNA

(2017) Jennifer A. Bohn et al.   Nature Communications

Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity

(2017) Takahide Kouno et al.   Nature Communications

APOBEC-mediated mutagenesis in urothelial carcinoma is associated with improved survival, mutations in DNA damage response genes, and immune response

(2017) Alexander P. Glaser et al.   Oncotarget

The 30 kb deletion in the APOBEC3 cluster decreases APOBEC3A and APOBEC3B expression and creates a transcriptionally active hybrid gene but does not associate with breast cancer in the European population

(2017) Katarzyna Klonowska et al.   Oncotarget

Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor Heterogeneity

(2017) Tony Mertz et al.   Genes

High expression of PD-1 ligands is associated with kataegis mutational signature and APOBEC3 alterations

(2017) Amélie Boichard et al.   OncoImmunology

Classical NF-κB pathway is responsible for APOBEC3B expression in cancer cells

(2016) Wataru Maruyama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Facilitating T Cell Infiltration in Tumor Microenvironment Overcomes Resistance to PD-L1 Blockade

(2016) Haidong Tang et al.   CANCER CELL

Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair

(2016) Nicholas J. Haradhvala et al.   CELL

APOBEC3A damages the cellular genome during DNA replication

(2016) Abby M. Green et al.   CELL CYCLE

Functions and Malfunctions of Mammalian DNA-Cytosine Deaminases

(2016) Sachini U. Siriwardena et al.   CHEMICAL REVIEWS

APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication

(2016) Vladimir B. Seplyarskiy et al.   GENOME RESEARCH

Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx

(2016) Ankur Chakravarthy et al.   JOURNAL OF CLINICAL ONCOLOGY

Predictive Markers for the Efficacy of Anti–PD-1/PD-L1 Antibodies in Lung Cancer

(2016) Takehito Shukuya et al.   Journal of Thoracic Oncology

Functional Upregulation of the DNA Cytosine Deaminase APOBEC3B by Polyomaviruses

(2016) Brandy Verhalen et al.   JOURNAL OF VIROLOGY

Bladder cancer

(2016) Ashish M Kamat et al.   LANCET

An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences

(2016) Charles A. Ishak et al.   MOLECULAR CELL

Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors

(2016) Candace D Middlebrooks et al.   NATURE GENETICS

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B

(2016) Ke Shi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Protein dynamics of human RPA and RAD51 on ssDNA during assembly and disassembly of the RAD51 filament

(2016) Chu Jian Ma et al.   NUCLEIC ACIDS RESEARCH

APOBEC3A associates with human papillomavirus genome integration in oropharyngeal cancers

(2016) S Kondo et al.   ONCOGENE

Transient overexpression of exogenous APOBEC3A causes C-to-U RNA editing of thousands of genes

(2016) Shraddha Sharma et al.   RNA Biology

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

(2016) N. McGranahan et al.   SCIENCE

Potential biomarker for checkpoint blockade immunotherapy and treatment strategy

(2016) Zhong-Yi Dong et al.   TUMOR BIOLOGY

The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis

(2016) Gabriel J. Starrett et al.   Nature Communications

Evolution of Neoantigen Landscape during Immune Checkpoint Blockade in Non–Small Cell Lung Cancer

(2016) Valsamo Anagnostou et al.   Cancer Discovery

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B

(2016) Ke Shi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA Replication

(2016) James I. Hoopes et al.   Cell Reports

Increased APOBEC3B Predicts Worse Outcomes in Lung Cancer: A Comprehensive Retrospective Study

(2016) Shumei Yan et al.   Journal of Cancer

The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer

(2016) E. K. Law et al.   Science Advances

The double-domain cytidine deaminase APOBEC3G is a cellular site-specific RNA editing enzyme

(2016) Shraddha Sharma et al.   Scientific Reports

Clusters of Multiple Mutations: Incidence and Molecular Mechanisms

(2015) Kin Chan et al.   Annual Review of Genetics

Identification of APOBEC3B promoter elements responsible for activation by human papillomavirus type 16 E6

(2015) Seiichiro Mori et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Diagnosis and Management of Urothelial Carcinoma In Situ of the Lower Urinary Tract: A Systematic Review

(2015) Rowan G. Casey et al.   EUROPEAN UROLOGY

Natural Polymorphisms and Oligomerization of Human APOBEC3H Contribute to Single-stranded DNA Scanning Ability

(2015) Yuqing Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of the Catalytic Domain of Human APOBEC3B and the Critical Structural Role for a Conserved Methionine

(2015) Sachini U. Siriwardena et al.   JOURNAL OF MOLECULAR BIOLOGY

Human Papillomavirus Carcinogenesis: an Identity Crisis in the Retinoblastoma Tumor Suppressor Pathway

(2015) Karl Munger et al.   JOURNAL OF VIROLOGY

Enhanced expression of PD L1 in cervical intraepithelial neoplasia and cervical cancers

(2015) Louisa Mezache et al.   MODERN PATHOLOGY

An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers

(2015) Kin Chan et al.   NATURE GENETICS

Genetic Basis for Clinical Response to CTLA-4 Blockade

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

(2015) Dung T. Le et al.   NEW ENGLAND JOURNAL OF MEDICINE

APOBEC3Bexpression in breast cancer reflects cellular proliferation, while a deletion polymorphism is associated with immune activation

(2015) David W. Cescon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence and structural determinants of human APOBEC3H deaminase and anti-HIV-1 activities

(2015) Mithun Mitra et al.   Retrovirology

Neoantigens in cancer immunotherapy

(2015) T. N. Schumacher et al.   SCIENCE

Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

(2015) N. A. Rizvi et al.   SCIENCE

Clonal status of actionable driver events and the timing of mutational processes in cancer evolution

(2015) Nicholas McGranahan et al.   Science Translational Medicine

Breaking bad: R-loops and genome integrity

(2015) Julie Sollier et al.   TRENDS IN CELL BIOLOGY

APOBEC3 genes: retroviral restriction factors to cancer drivers

(2015) Stephen Henderson et al.   TRENDS IN MOLECULAR MEDICINE

High APOBEC3B expression is a predictor of recurrence in patients with low-risk clear cell renal cell carcinoma

(2015) Le Xu et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma

(2015) Brian A. Walker et al.   Nature Communications

APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages

(2015) Shraddha Sharma et al.   Nature Communications

APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity

(2015) C. Swanton et al.   Cancer Discovery

APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions

(2015) Marat D. Kazanov et al.   Cell Reports

APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer

(2015) Manikandan Periyasamy et al.   Cell Reports

APOBEC3A Is Implicated in a Novel Class of G-to-A mRNA Editing in WT1 Transcripts

(2015) Ahmadreza Niavarani et al.   PLoS One

FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis

(2015) Catherine E. Waters et al.   Oncotarget

Clustered and genome-wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitness

(2014) Steven A. Roberts et al.   BIOESSAYS

TP53 Mutation Spectrum in Breast Cancer Is Subtype Specific and Has Distinct Prognostic Relevance

(2014) L. Silwal-Pandit et al.   CLINICAL CANCER RESEARCH

Error-free versus mutagenic processing of genomic uracil—Relevance to cancer

(2014) Hans E. Krokan et al.   DNA REPAIR

APOBEC3A Functions as a Restriction Factor of Human Papillomavirus

(2014) Cody J. Warren et al.   JOURNAL OF VIROLOGY

MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer

(2014) Thomas Powles et al.   NATURE

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

(2014) Roy S. Herbst et al.   NATURE

Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer

(2014) Serena Nik-Zainal et al.   NATURE GENETICS

Concentration-Dependent Exchange of Replication Protein A on Single-Stranded DNA Revealed by Single-Molecule Imaging

(2014) Bryan Gibb et al.   PLoS One

The Antiviral Restriction Factors IFITM1, 2 and 3 Do Not Inhibit Infection of Human Papillomavirus, Cytomegalovirus and Adenovirus

(2014) Cody J. Warren et al.   PLoS One

A DNA Sequence Recognition Loop on APOBEC3A Controls Substrate Specificity

(2014) Eric C. Logue et al.   PLoS One

Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

(2014) J. Zhang et al.   SCIENCE

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

(2014) E. C. de Bruin et al.   SCIENCE

Human Papillomavirus E6 Triggers Upregulation of the Antiviral and Cancer Genomic DNA Deaminase APOBEC3B

(2014) Valdimara C. Vieira et al.   mBio

A prevalent cancer susceptibility APOBEC3A hybrid allele bearing APOBEC3B 3′UTR enhances chromosomal DNA damage

(2014) Vincent Caval et al.   Nature Communications

APOBEC-Mediated Cytosine Deamination Links PIK3CA Helical Domain Mutations to Human Papillomavirus-Driven Tumor Development

(2014) Stephen Henderson et al.   Cell Reports

Break-Induced Replication Is a Source of Mutation Clusters Underlying Kataegis

(2014) Cynthia J. Sakofsky et al.   Cell Reports

APOBEC3A deaminates transiently exposed single-strand DNA during LINE-1 retrotransposition

(2014) Sandra R Richardson et al.   eLife

Suppression of APOBEC3-mediated restriction of HIV-1 by Vif

(2014) Yuqing Feng et al.   Frontiers in Microbiology

Elevated APOBEC3B Correlates with Poor Outcomes for Estrogen-Receptor-Positive Breast Cancers

(2014) Anieta M. Sieuwerts et al.   Hormones & Cancer

HPV infection in squamous cell carcinomas arising from different mucosal sites of the head and neck region. Is p16 immunohistochemistry a reliable surrogate marker?

(2013) F Bussu et al.   BRITISH JOURNAL OF CANCER

APOBEC3 Cytidine Deaminases in Double-Strand DNA Break Repair and Cancer Promotion

(2013) R. Nowarski et al.   CANCER RESEARCH

APOBEC3 deletion polymorphism is associated with breast cancer risk among women of European ancestry

(2013) D. Xuan et al.   CARCINOGENESIS

Subcellular localization of the APOBEC3 proteins during mitosis and implications for genomic DNA deamination

(2013) Lela Lackey et al.   CELL CYCLE

How do proteins locate specific targets in DNA?

(2013) Sy Redding et al.   CHEMICAL PHYSICS LETTERS

The choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis

(2013) Kin Chan et al.   DNA REPAIR

APOBEC3 Multimerization Correlates with HIV-1 Packaging and Restriction Activity in Living Cells

(2013) Jinhui Li et al.   JOURNAL OF MOLECULAR BIOLOGY

A Common Deletion in the APOBEC3 Genes and Breast Cancer Risk

(2013) Jirong Long et al.   JNCI-Journal of the National Cancer Institute

The inhibition of hepatitis B virus by APOBEC cytidine deaminases

(2013) E. M. Janahi et al.   JOURNAL OF VIRAL HEPATITIS

APOBEC3 Deaminases Induce Hypermutation in Human Papillomavirus 16 DNA upon Beta Interferon Stimulation

(2013) Z. Wang et al.   JOURNAL OF VIROLOGY

Landscape of genomic alterations in cervical carcinomas

(2013) Akinyemi I. Ojesina et al.   NATURE

APOBEC3B is an enzymatic source of mutation in breast cancer

(2013) Michael B. Burns et al.   NATURE

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

APOBEC3B mutagenesis in cancer

(2013) Kawai J Kuong et al.   NATURE GENETICS

Evidence for APOBEC3B mutagenesis in multiple human cancers

(2013) Michael B Burns et al.   NATURE GENETICS

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

(2013) Steven A Roberts et al.   NATURE GENETICS

Human APOBEC3A Isoforms Translocate to the Nucleus and Induce DNA Double Strand Breaks Leading to Cell Stress and Death

(2013) Bianka Mussil et al.   PLoS One

Cancer mutation signatures, DNA damage mechanisms, and potential clinical implications

(2013) Reuben S Harris   Genome Medicine

The Role of Cytidine Deaminases on Innate Immune Responses against Human Viral Infections

(2013) Valdimara C. Vieira et al.   Biomed Research International

DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis

(2013) Benjamin JM Taylor et al.   eLife

Intrinsic immunity against retrotransposons by APOBEC cytidine deaminases

(2013) Atsushi Koito et al.   Frontiers in Microbiology

APOBEC3G enhances lymphoma cell radioresistance by promoting cytidine deaminase-dependent DNA repair

(2012) R. Nowarski et al.   BLOOD

Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers

(2012) Ramaswamy Govindan et al.   CELL

Mutational Processes Molding the Genomes of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

The Life History of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

Epidemiology and Risk Factors of Urothelial Bladder Cancer

(2012) Maximilian Burger et al.   EUROPEAN UROLOGY

EUROGIN 2011 roadmap on prevention and treatment of HPV-related disease

(2012) Marc Arbyn et al.   INTERNATIONAL JOURNAL OF CANCER

Methylcytosine and Normal Cytosine Deamination by the Foreign DNA Restriction Enzyme APOBEC3A

(2012) Michael A. Carpenter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions

(2012) Steven A. Roberts et al.   MOLECULAR CELL

The landscape of cancer genes and mutational processes in breast cancer

(2012) Philip J. Stephens et al.   NATURE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Melanoma genome sequencing reveals frequent PREX2 mutations

(2012) Michael F. Berger et al.   NATURE

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

(2012) Christina Curtis et al.   NATURE

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Initiation of Genome Instability and Preneoplastic Processes through Loss of Fhit Expression

(2012) Joshua C. Saldivar et al.   PLoS Genetics

Endogenous Origins of HIV-1 G-to-A Hypermutation and Restriction in the Nonpermissive T Cell Line CEM2n

(2012) Eric W. Refsland et al.   PLoS Pathogens

Retroelements versus APOBEC3 family members: No great escape from the magnificent seven

(2012) Juan F. Arias et al.   Frontiers in Microbiology

Relationship of Extreme Chromosomal Instability with Long-term Survival in a Retrospective Analysis of Primary Breast Cancer

(2011) R. Roylance et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer

(2011) N. J. Birkbak et al.   CANCER RESEARCH

The RNA Exosome Targets the AID Cytidine Deaminase to Both Strands of Transcribed Duplex DNA Substrates

(2011) Uttiya Basu et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

APOBEC3A can activate the DNA damage response and cause cell-cycle arrest

(2011) Sébastien Landry et al.   EMBO REPORTS

Polymorphism in Human APOBEC3H Affects a Phenotype Dominant for Subcellular Localization and Antiviral Activity

(2011) M. M. H. Li et al.   JOURNAL OF VIROLOGY

Exome sequencing identifies GRIN2A as frequently mutated in melanoma

(2011) Xiaomu Wei et al.   NATURE GENETICS

The antiviral factor APOBEC3G enhances the recognition of HIV-infected primary T cells by natural killer cells

(2011) Jason M Norman et al.   NATURE IMMUNOLOGY

Large-scale DNA editing of retrotransposons accelerates mammalian genome evolution

(2011) Shai Carmi et al.   Nature Communications

APOBEC3A Is a Specific Inhibitor of the Early Phases of HIV-1 Infection in Myeloid Cells

(2011) Gregory Berger et al.   PLoS Pathogens

Determinants of sequence-specificity within human AID and APOBEC3G

(2010) Michael A. Carpenter et al.   DNA REPAIR

Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeutics

(2010) John S. Albin et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

(2010)   NATURE

APOBEC3 proteins mediate the clearance of foreign DNA from human cells

(2010) Mark D Stenglein et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction

(2010) Eric W. Refsland et al.   NUCLEIC ACIDS RESEARCH

A Portable Hot Spot Recognition Loop Transfers Sequence Preferences from APOBEC Family Members to Activation-induced Cytidine Deaminase

(2009) Rahul M. Kohli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The antiviral factor APOBEC3G improves CTL recognition of cultured HIV-infected T cells

(2009) Nicoletta Casartelli et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Oral Sexual Behaviors Associated with Prevalent Oral Human Papillomavirus Infection

(2009) Gypsyamber D’Souza et al.   JOURNAL OF INFECTIOUS DISEASES

Defining APOBEC3 Expression Patterns in Human Tissues and Hematopoietic Cell Subsets

(2009) F. A. Koning et al.   JOURNAL OF VIROLOGY

The APOBEC3 Cytidine Deaminases: An Innate Defensive Network Opposing Exogenous Retroviruses and Endogenous Retroelements

(2008) Ya-Lin Chiu et al.   Annual Review of Immunology

Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1

(2008) Fulvia Terenzi et al.   EMBO JOURNAL

Comparison of Cellular Ribonucleoprotein Complexes Associated with the APOBEC3F and APOBEC3G Antiviral Proteins

(2008) S. Gallois-Montbrun et al.   JOURNAL OF VIROLOGY

Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications

(2008) Lauren G. Holden et al.   NATURE

Evidence for Editing of Human Papillomavirus DNA by APOBEC3 in Benign and Precancerous Lesions

(2008) J.-P. Vartanian et al.   SCIENCE

The AID/APOBEC family of nucleic acid mutators

(2008) Silvestro G Conticello   GENOME BIOLOGY