Human APOBEC3A Isoforms Translocate to the Nucleus and Induce DNA Double Strand Breaks Leading to Cell Stress and Death
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Title
Human APOBEC3A Isoforms Translocate to the Nucleus and Induce DNA Double Strand Breaks Leading to Cell Stress and Death
Authors
Keywords
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Journal
PLoS One
Volume 8, Issue 8, Pages e73641
Publisher
Public Library of Science (PLoS)
Online
2013-08-21
DOI
10.1371/journal.pone.0073641
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Note: Only part of the references are listed.- APOBEC3B is an enzymatic source of mutation in breast cancer
- (2013) Michael B. Burns et al. NATURE
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- (2012) Serena Nik-Zainal et al. CELL
- Evidence of associations of APOBEC3B gene deletion with susceptibility to persistent HBV infection and hepatocellular carcinoma
- (2012) T. Zhang et al. HUMAN MOLECULAR GENETICS
- Methylcytosine and Normal Cytosine Deamination by the Foreign DNA Restriction Enzyme APOBEC3A
- (2012) Michael A. Carpenter et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human Tribbles 3 Protects Nuclear DNA from Cytidine Deamination by APOBEC3A
- (2012) Marie-Ming Aynaud et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Biochemical Analysis of Hypermutation by the Deoxycytidine Deaminase APOBEC3A
- (2012) Robin P. Love et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- APOBEC3A, APOBEC3B, and APOBEC3H Haplotype 2 Restrict Human T-Lymphotropic Virus Type 1
- (2012) M. Ooms et al. JOURNAL OF VIROLOGY
- Efficient deamination of 5-methylcytosines in DNA by human APOBEC3A, but not by AID or APOBEC3G
- (2012) Priyanga Wijesinghe et al. NUCLEIC ACIDS RESEARCH
- Evolution of the Primate APOBEC3A Cytidine Deaminase Gene and Identification of Related Coding Regions
- (2012) Michel Henry et al. PLoS One
- Studies on the Restriction of Murine Leukemia Viruses by Mouse APOBEC3
- (2012) Silvia Sanchez-Martinez et al. PLoS One
- Role of retroviral restriction factors in the interferon- -mediated suppression of HIV-1 in vivo
- (2012) S. K. Pillai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- APOBEC3B can impair genomic stability by inducing base substitutions in genomic DNA in human cells
- (2012) Masanobu Shinohara et al. Scientific Reports
- Dissecting T Cell Contraction In Vivo Using a Genetically Encoded Reporter of Apoptosis
- (2012) Kym R. Garrod et al. Cell Reports
- Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development
- (2011) Philip J. Stephens et al. CELL
- Where did they come from? The origin of endogenous γ-H2AX foci in tumor cells
- (2011) Asako J. Nakamura et al. CELL CYCLE
- APOBEC3A can activate the DNA damage response and cause cell-cycle arrest
- (2011) Sébastien Landry et al. EMBO REPORTS
- Genetic Editing of Herpes Simplex Virus 1 and Epstein-Barr Herpesvirus Genomes by Human APOBEC3 Cytidine Deaminases in Culture and In Vivo
- (2011) R. Suspene et al. JOURNAL OF VIROLOGY
- Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism
- (2011) R. Suspene et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- APOBEC3A Is a Specific Inhibitor of the Early Phases of HIV-1 Infection in Myeloid Cells
- (2011) Gregory Berger et al. PLoS Pathogens
- DNA binding, cytotoxicity, and apoptotic-inducing activity of ruthenium(II) polypyridyl complex
- (2010) P. Zhang et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Innate Immune Signaling Induces High Levels of TC-specific Deaminase Activity in Primary Monocyte-derived Cells through Expression of APOBEC3A Isoforms
- (2010) Beth K. Thielen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- APOBEC3 proteins mediate the clearance of foreign DNA from human cells
- (2010) Mark D Stenglein et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction
- (2010) Eric W. Refsland et al. NUCLEIC ACIDS RESEARCH
- Massive APOBEC3 Editing of Hepatitis B Viral DNA in Cirrhosis
- (2010) Jean-Pierre Vartanian et al. PLoS Pathogens
- Delayed kinetics of DNA double-strand break processing in normal and pathological aging
- (2009) Olga A. Sedelnikova et al. AGING CELL
- Human Immunodeficiency Virus, Restriction Factors, and Interferon
- (2009) Stuart Neil et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Induction of APOBEC3 In Vivo Causes Increased Restriction of Retrovirus Infection
- (2009) C. M. Okeoma et al. JOURNAL OF VIROLOGY
- Defining APOBEC3 Expression Patterns in Human Tissues and Hematopoietic Cell Subsets
- (2009) F. A. Koning et al. JOURNAL OF VIROLOGY
- The cancer genome
- (2009) Michael R. Stratton et al. NATURE
- A coming-of-age story: activation-induced cytidine deaminase turns 10
- (2009) Rebecca K Delker et al. NATURE IMMUNOLOGY
- Genetic Editing of HBV DNA by Monodomain Human APOBEC3 Cytidine Deaminases and the Recombinant Nature of APOBEC3G
- (2009) Michel Henry et al. PLoS One
- Balancing AID and DNA repair during somatic hypermutation
- (2009) Man Liu et al. TRENDS IN IMMUNOLOGY
- The APOBEC3 Cytidine Deaminases: An Innate Defensive Network Opposing Exogenous Retroviruses and Endogenous Retroelements
- (2008) Ya-Lin Chiu et al. Annual Review of Immunology
- AID Is Required for the Chromosomal Breaks in c-myc that Lead to c-myc/IgH Translocations
- (2008) Davide F. Robbiani et al. CELL
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- (2008) P BENNETT et al. FREE RADICAL BIOLOGY AND MEDICINE
- APOBEC3G upregulation by alpha interferon restricts human immunodeficiency virus type 1 infection in human peripheral plasmacytoid dendritic cells
- (2008) F.-x. Wang et al. JOURNAL OF GENERAL VIROLOGY
- APOBEC3-Independent Interferon-Induced Viral Clearance in Hepatitis B Virus Transgenic Mice
- (2008) P. Turelli et al. JOURNAL OF VIROLOGY
- DNA strand breaks, neurodegeneration and aging in the brain
- (2008) Sachin Katyal et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Two levels of protection for the B cell genome during somatic hypermutation
- (2008) Man Liu et al. NATURE
- Powerful mutators lurking in the genome
- (2008) V. Petit et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Evidence for Editing of Human Papillomavirus DNA by APOBEC3 in Benign and Precancerous Lesions
- (2008) J.-P. Vartanian et al. SCIENCE
- Age to survive: DNA damage and aging
- (2008) Björn Schumacher et al. TRENDS IN GENETICS
- Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence
- (2008) Asako J Nakamura et al. Epigenetics & Chromatin
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