Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

(2014) Marco Gerlinger et al.   NATURE GENETICS

Cancer heterogeneity: implications for targeted therapeutics

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Parallel evolution of tumour subclones mimics diversity between tumours

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Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

(2013) Kristian Cibulskis et al.   NATURE BIOTECHNOLOGY

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

(2013) Steven A Roberts et al.   NATURE GENETICS

Emerging patterns of somatic mutations in cancer

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Results of Initial Low-Dose Computed Tomographic Screening for Lung Cancer

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics

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Cancer Genome Landscapes

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Cancer heterogeneity and “The Struggle for Existence”: Diagnostic and analytical challenges

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Intratumor Heterogeneity: Evolution through Space and Time

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Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers

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Mutational Processes Molding the Genomes of 21 Breast Cancers

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Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

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The Life History of 21 Breast Cancers

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Role of intratumoural heterogeneity in cancer drug resistance: molecular and clinical perspectives

(2012) Nicholas A. Saunders et al.   EMBO Molecular Medicine

VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

(2012) D. C. Koboldt et al.   GENOME RESEARCH

The landscape of cancer genes and mutational processes in breast cancer

(2012) Philip J. Stephens et al.   NATURE

Performance comparison of benchtop high-throughput sequencing platforms

(2012) Nicholas J Loman et al.   NATURE BIOTECHNOLOGY

Absolute quantification of somatic DNA alterations in human cancer

(2012) Scott L Carter et al.   NATURE BIOTECHNOLOGY

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intratumor Heterogeneity: Seeing the Wood for the Trees

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Identification and correction of systematic error in high-throughput sequence data

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Tumour evolution inferred by single-cell sequencing

(2011) Nicholas Navin et al.   NATURE

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Genetic variegation of clonal architecture and propagating cells in leukaemia

(2010) Kristina Anderson et al.   NATURE

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

(2010) Shinichi Yachida et al.   NATURE

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Allele-specific copy number analysis of tumors

(2010) P. Van Loo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets

(2010) Charles Swanton et al.   Genome Medicine

Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads

(2009) K. Ye et al.   BIOINFORMATICS

Inferring tumor progression from genomic heterogeneity

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Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

(2009) Sohrab P. Shah et al.   NATURE

Somatic mutations affect key pathways in lung adenocarcinoma

(2008) Li Ding et al.   NATURE

Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing

(2008) P. J. Campbell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA