Hdac3 deletion in myeloid progenitor cells enhances bone healing in females and limits osteoclast fusion via Pmepa1

Deficiency in the phosphatase PHLPP1 suppresses osteoclast-mediated bone resorption and enhances bone formation in mice

(2019) Anna M. Mattson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TMEPAI family: involvement in regulation of multiple signalling pathways

(2018) Susumu Itoh et al.   JOURNAL OF BIOCHEMISTRY

DNA methylation and FoxO3a regulate PHLPP1 expression in chondrocytes

(2018) Clara M. Castillejo Becerra et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Role of the Immune Cells in Fracture Healing

(2018) Gurpreet S. Baht et al.   Current Osteoporosis Reports

Prostate transmembrane protein androgen induced 1 is induced by activation of osteoclasts and regulates bone resorption

(2018) Xianghe Xu et al.   FASEB JOURNAL

Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice

(2018) Linda Vi et al.   Nature Communications

Misconceptions, Misuses, and Misinterpretations of P Values and Significance Testing

(2017) Joel J. Gagnier et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Loss of Hdac3 in osteoprogenitors increases bone expression of osteoprotegerin, improving systemic insulin sensitivity

(2017) Meghan E. McGee-Lawrence et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Pmepa1 induced by RANKL-p38 MAPK pathway has a novel role in osteoclastogenesis

(2017) Noboru Funakubo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge

(2017) Matthew J. Emmett et al.   NATURE

Osteoimmunology in Bone Fracture Healing

(2017) Takehito Ono et al.   Current Osteoporosis Reports

Effects of Aging on Fracture Healing

(2017) Dan Clark et al.   Current Osteoporosis Reports

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

Minireview: The Link Between ERα Corepressors and Histone Deacetylases in Tamoxifen Resistance in Breast Cancer

(2016) Stéphanie Légaré et al.   MOLECULAR ENDOCRINOLOGY

Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling

(2016) Lomeli R. Carpio et al.   Science Signaling

The Alternative Faces of Macrophage Generate Osteoclasts

(2016) N. Lampiasi et al.   Biomed Research International

Histone Deacetylases in Cartilage Homeostasis and Osteoarthritis

(2016) Lomeli R. Carpio et al.   Current Rheumatology Reports

Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling

(2016) Lomeli R. Carpio et al.   Science Signaling

Oncostatin M, an Inflammatory Cytokine Produced by Macrophages, Supports Intramembranous Bone Healing in a Mouse Model of Tibia Injury

(2015) Pierre Guihard et al.   AMERICAN JOURNAL OF PATHOLOGY

Macrophages Promote Osteoblastic Differentiation In Vivo: Implications in Fracture Repair and Bone Homeostasis

(2015) Linda Vi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Hdac3 Deficiency Increases Marrow Adiposity and Induces Lipid Storage and Glucocorticoid Metabolism in Osteochondroprogenitor Cells

(2015) Meghan E McGee-Lawrence et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Histone Deacetylases in Bone Development and Skeletal Disorders

(2015) Elizabeth W. Bradley et al.   PHYSIOLOGICAL REVIEWS

Fracture Healing via Periosteal Callus Formation Requires Macrophages for Both Initiation and Progression of Early Endochondral Ossification

(2014) Liza J. Raggatt et al.   AMERICAN JOURNAL OF PATHOLOGY

Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions

(2014) M. A. Hoeksema et al.   EMBO Molecular Medicine

Osteal Tissue Macrophages Are Intercalated throughout Human and Mouse Bone Lining Tissues and Regulate Osteoblast Function In Vitro and In Vivo

(2014) M. K. Chang et al.   JOURNAL OF IMMUNOLOGY

Macrophages migrate in an activation-dependent manner to chemokines involved in neuroinflammation

(2014) Daphne YS Vogel et al.   Journal of Neuroinflammation

Fracture healing: mechanisms and interventions

(2014) Thomas A. Einhorn et al.   Nature Reviews Rheumatology

Modulation of Osteoclastogenesis with Macrophage M1- and M2-Inducing Stimuli

(2014) Sujeeve Jeganathan et al.   PLoS One

Osteal macrophages support physiologic skeletal remodeling and anabolic actions of parathyroid hormone in bone

(2014) S. W. Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biologic therapies and systemic bone loss in rheumatoid arthritis

(2013) Theodoros Dimitroulas et al.   AUTOIMMUNITY REVIEWS

Sclerostin deficient mice rapidly heal bone defects by activating β-catenin and increasing intramembranous ossification

(2013) Meghan E. McGee-Lawrence et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Histone Deacetylase 3 Suppression Increases PH Domain and Leucine-rich Repeat Phosphatase (Phlpp)1 Expression in Chondrocytes to Suppress Akt Signaling and Matrix Secretion

(2013) Elizabeth W. Bradley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cord Blood-Derived Macrophage-Lineage Cells Rapidly Stimulate Osteoblastic Maturation in Mesenchymal Stem Cells in a Glycoprotein-130 Dependent Manner

(2013) Tania J. Fernandes et al.   PLoS One

Combination of Tumor Necrosis Factor α and Interleukin-6 Induces Mouse Osteoclast-like Cells With Bone Resorption Activity Both In Vitro and In Vivo

(2013) Kazuhiro Yokota et al.   Arthritis & Rheumatology

Lipopolysaccharide induces multinuclear cell from RAW264.7 line with increased phagocytosis activity

(2012) Mayumi Nakanishi-Matsui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Histone deacetylase 3 is required for maintenance of bone mass during aging

(2012) Meghan E. McGee-Lawrence et al.   BONE

Effect of monocytes/macrophages on the early osteogenic differentiation of hBMSCs

(2012) R. P. Pirraco et al.   Journal of Tissue Engineering and Regenerative Medicine

Monocytes Induce STAT3 Activation in Human Mesenchymal Stem Cells to Promote Osteoblast Formation

(2012) Vicky Nicolaidou et al.   PLoS One

Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages

(2012) X. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Osteogenesis in Mesenchymal Stem Cells by Activated Monocytes/Macrophages Depends on Oncostatin M Signaling

(2012) Pierre Guihard et al.   STEM CELLS

Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation

(2011) S. E. Mullican et al.   GENES & DEVELOPMENT

HDAC3 and HDAC7 Have Opposite Effects on Osteoclast Differentiation

(2011) Lan Pham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model

(2011) Kylie A Alexander et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Histone Deacetylase 3 Depletion in Osteo/Chondroprogenitor Cells Decreases Bone Density and Increases Marrow Fat

(2010) David F. Razidlo et al.   PLoS One

Histone deacetylase inhibitors decrease proliferation potential and multilineage differentiation capability of human mesenchymal stem cells

(2009) S. Lee et al.   CELL PROLIFERATION

Histone Deacetylase Inhibitors In Inflammatory Disease

(2009) Maria Halili et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Osteal macrophages: A new twist on coupling during bone dynamics

(2008) Allison R. Pettit et al.   BONE

Interleukin-6 Inhibits Receptor Activator of Nuclear Factor κB Ligand-Induced Osteoclastogenesis by Diverting Cells into the Macrophage Lineage: Key Role of Serine727Phosphorylation of Signal Transducer and Activator of Transcription 3

(2008) Laurence Duplomb et al.   ENDOCRINOLOGY

Interleukin-4 and Interleukin-13 Stimulate the Osteoclast Inhibitor Osteoprotegerin by Human Endothelial Cells Through the STAT6 Pathway

(2008) Nicola C Stein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Deletion of Histone Deacetylase 3 Reveals Critical Roles in S Phase Progression and DNA Damage Control

(2008) Srividya Bhaskara et al.   MOLECULAR CELL

NFATc1 Induces Osteoclast Fusion Via Up-Regulation of Atp6v0d2 and the Dendritic Cell-Specific Transmembrane Protein (DC-STAMP)

(2007) Kabsun Kim et al.   MOLECULAR ENDOCRINOLOGY