Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling

Chromatin modifiers and histone modifications in bone formation, regeneration, and therapeutic intervention for bone-related disease

(2015) Jonathan A.R. Gordon et al.   BONE

Osteoclast TGF-β Receptor Signaling Induces Wnt1 Secretion and Couples Bone Resorption to Bone Formation

(2015) Megan M Weivoda et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Hdac3 Deficiency Increases Marrow Adiposity and Induces Lipid Storage and Glucocorticoid Metabolism in Osteochondroprogenitor Cells

(2015) Meghan E McGee-Lawrence et al.   JOURNAL OF BONE AND MINERAL RESEARCH

FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3

(2015) Liqing Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Histone Deacetylases in Bone Development and Skeletal Disorders

(2015) Elizabeth W. Bradley et al.   PHYSIOLOGICAL REVIEWS

JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age

(2015) Ming Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Effects of Class-Specific Histone Deacetylase Inhibitors on the Development of Limbs During Organogenesis

(2015) France-Hélène Paradis et al.   TOXICOLOGICAL SCIENCES

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

HiChIP: a high-throughput pipeline for integrative analysis of ChIP-Seq data

(2014) Huihuang Yan et al.   BMC BIOINFORMATICS

MAP-RSeq: Mayo Analysis Pipeline for RNA sequencing

(2014) Krishna R Kalari et al.   BMC BIOINFORMATICS

ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases

(2014) Li Shen et al.   BMC GENOMICS

High-Resolution Molecular Validation of Self-Renewal and Spontaneous Differentiation in Clinical-Grade Adipose-Tissue Derived Human Mesenchymal Stem Cells

(2014) Amel Dudakovic et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Mechanisms behind the Therapeutic Activity of BET Bromodomain Inhibition

(2014) Junwei Shi et al.   MOLECULAR CELL

A subset of chondrogenic cells provides early mesenchymal progenitors in growing bones

(2014) Noriaki Ono et al.   NATURE CELL BIOLOGY

Class I Histone Deacetylase Inhibition Modulates Metalloproteinase Expression and Blocks Cytokine-Induced Cartilage Degradation

(2013) Kirsty L. Culley et al.   ARTHRITIS AND RHEUMATISM

Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression

(2013) Nikhil Singh et al.   DEVELOPMENTAL BIOLOGY

Histone Deacetylase 3 Suppression Increases PH Domain and Leucine-rich Repeat Phosphatase (Phlpp)1 Expression in Chondrocytes to Suppress Akt Signaling and Matrix Secretion

(2013) Elizabeth W. Bradley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chondroprotection by histone deacetylase inhibition

(2013) Emma Leah   Nature Reviews Rheumatology

Histone deacetylase inhibitors increase microRNA-146a expression and enhance negative regulation of interleukin-1β signaling in osteoarthritis fibroblast-like synoviocytes

(2013) J.H. Wang et al.   OSTEOARTHRITIS AND CARTILAGE

RSeQC: quality control of RNA-seq experiments

(2012) Liguo Wang et al.   BIOINFORMATICS

Histone deacetylase 3 is required for maintenance of bone mass during aging

(2012) Meghan E. McGee-Lawrence et al.   BONE

Pro-Inflammatory Cytokines Produced by Growth Plate Chondrocytes May Act Locally to Modulate Longitudinal Bone Growth

(2012) Paola Fernandez-Vojvodich et al.   Hormone Research in Paediatrics

Fracture healing under healthy and inflammatory conditions

(2012) Lutz Claes et al.   Nature Reviews Rheumatology

Initial application of EPIC-μCT to assess mouse articular cartilage morphology and composition: effects of aging and treadmill running

(2012) N. Kotwal et al.   OSTEOARTHRITIS AND CARTILAGE

Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts

(2011) Meghan E. McGee-Lawrence et al.   BONE

Histone Deacetylase 3 Regulates Smooth Muscle Differentiation in Neural Crest Cells and Development of the Cardiac Outflow Tract

(2011) Nikhil Singh et al.   CIRCULATION RESEARCH

HDAC inhibitors: modulating leukocyte differentiation, survival, proliferation and inflammation

(2011) Matthew J Sweet et al.   IMMUNOLOGY AND CELL BIOLOGY

Histone deacetylase inhibitors as suppressors of bone destruction in inflammatory diseases

(2011) Melissa D. Cantley et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Anti-inflammatory Agents: Present and Future

(2010) Charles A. Dinarello   CELL

Osteoblast Precursors, but Not Mature Osteoblasts, Move into Developing and Fractured Bones along with Invading Blood Vessels

(2010) Christa Maes et al.   DEVELOPMENTAL CELL

Mechanistic Insights into the Events That Lead to Synergistic Induction of Interleukin 6 Transcription upon Activation of the Aryl Hydrocarbon Receptor and Inflammatory Signaling

(2010) Brett C. DiNatale et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity

(2010) Eric Hesse et al.   JOURNAL OF CELL BIOLOGY

Histone Deacetylase Inhibitors Suppress Inflammatory Activation of Rheumatoid Arthritis Patient Synovial Macrophages and Tissue

(2010) Aleksander M. Grabiec et al.   JOURNAL OF IMMUNOLOGY

Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS

(2010) Maria A. Halili et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The binding modes and binding affinities of artemisinin derivatives with Plasmodium falciparum Ca2+-ATPase (PfATP6)

(2010) Pradeep Kumar Naik et al.   JOURNAL OF MOLECULAR MODELING

Alleviation of osteoarthritis by Trichostatin A, a histone deacetylase inhibitor, in experimental osteoarthritis

(2010) Wei-Ping Chen et al.   MOLECULAR BIOLOGY REPORTS

The Histone Deacetylase Inhibitor, Vorinostat, Reduces Tumor Growth at the Metastatic Bone Site and Associated Osteolysis, but Promotes Normal Bone Loss

(2010) J. Pratap et al.   MOLECULAR CANCER THERAPEUTICS

Histone Deacetylase 3 Depletion in Osteo/Chondroprogenitor Cells Decreases Bone Density and Increases Marrow Fat

(2010) David F. Razidlo et al.   PLoS One

Genetic Control of Bone Formation

(2009) Gerard Karsenty et al.   Annual Review of Cell and Developmental Biology

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Trichostatin A inhibits osteoclastogenesis and bone resorption by suppressing the induction of c-Fos by RANKL

(2009) Ha-Neui Kim et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Deletion of Histone Deacetylase 3 Reveals Critical Roles in S Phase Progression and DNA Damage Control

(2008) Srividya Bhaskara et al.   MOLECULAR CELL

Primary culture and phenotyping of murine chondrocytes

(2008) Marjolaine Gosset et al.   Nature Protocols

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

(2008) Michael Haberland et al.   NATURE REVIEWS GENETICS

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY