Visualising G-quadruplex DNA dynamics in live cells by fluorescence lifetime imaging microscopy

Custom DNA Microarrays Reveal Diverse Binding Preferences of Proteins and Small Molecules to Thousands of G-Quadruplexes

(2020) Sreejana Ray et al.   ACS Chemical Biology

Small Molecule Fluorescent Probes for G- Quadruplex Visualization as Potential Cancer Theranostic Agents

(2019) Pallavi Chilka et al.   MOLECULES

Recent developments in novel blue/green/red/NIR small fluorescent probes for in cellulo tracking of RNA/DNA G-quadruplexes

(2019) Anup Pandith et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS

Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and high-throughput sequencing

(2018) Robert Hänsel-Hertsch et al.   Nature Protocols

Ethyl-substitutive Thioflavin T as a highly-specific fluorescence probe for detecting G-quadruplex structure

(2018) Ai-jiao Guan et al.   Scientific Reports

The G-quadruplex fluorescent probe 3,6-bis(1-methyl-2-vinyl-pyridinium) carbazole diiodide as a biosensor for human cancers

(2018) Ting-Yuan Tseng et al.   Scientific Reports

Binding of Small Molecules to G-quadruplex DNA in Cells Revealed by Fluorescence Lifetime Imaging Microscopy of o-BMVC Foci

(2018) Ting-Yuan Tseng et al.   MOLECULES

DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells

(2018) Alessio De Magis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploring viscosity, polarity and temperature sensitivity of BODIPY-based molecular rotors

(2017) Aurimas Vyšniauskas et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Quadruplex nucleic acids as targets for anticancer therapeutics

(2017) Stephen Neidle   Nature Reviews Chemistry

NMR Structure of a Triangulenium-Based Long-Lived Fluorescence Probe Bound to a G-Quadruplex

(2016) Anita Kotar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Trianguleniums as Optical Probes for G-Quadruplexes: A Photophysical, Electrochemical, and Computational Study

(2016) Arun Shivalingam et al.   CHEMISTRY-A EUROPEAN JOURNAL

DNA damage processing at telomeres: The ends justify the means

(2016) Elise Fouquerel et al.   DNA REPAIR

Quadruplex Nucleic Acids as Novel Therapeutic Targets

(2016) Stephen Neidle   JOURNAL OF MEDICINAL CHEMISTRY

G-quadruplex structures mark human regulatory chromatin

(2016) Robert Hänsel-Hertsch et al.   NATURE GENETICS

G-quadruplexes and helicases

(2016) Oscar Mendoza et al.   NUCLEIC ACIDS RESEARCH

Re-evaluation of G-quadruplex propensity with G4Hunter

(2016) Amina Bedrat et al.   NUCLEIC ACIDS RESEARCH

Thioflavin T as an efficient fluorescence sensor for selective recognition of RNA G-quadruplexes

(2016) Shujuan Xu et al.   Scientific Reports

Getting Ready for the Dance: FANCJ Irons Out DNA Wrinkles

(2016) Sanjay Bharti et al.   Genes

G-quadruplex ligands exhibit differential G-tetrad selectivity

(2015) D. D. Le et al.   CHEMICAL COMMUNICATIONS

High-throughput sequencing of DNA G-quadruplex structures in the human genome

(2015) Vicki S Chambers et al.   NATURE BIOTECHNOLOGY

Human regulator of telomere elongation helicase 1 (RTEL1) is required for the nuclear and cytoplasmic trafficking of pre-U2 RNA

(2015) Michael Schertzer et al.   NUCLEIC ACIDS RESEARCH

G-quadruplexes and their regulatory roles in biology

(2015) Daniela Rhodes et al.   NUCLEIC ACIDS RESEARCH

The interactions between a small molecule and G-quadruplexes are visualized by fluorescence lifetime imaging microscopy

(2015) Arun Shivalingam et al.   Nature Communications

Existence and consequences of G-quadruplex structures in DNA

(2014) Pierre Murat et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Metabolism of DNA secondary structures at the eukaryotic replication fork

(2014) Ana María León-Ortiz et al.   DNA REPAIR

Effect of fixation procedures on the fluorescence lifetimes ofAequorea victoriaderived fluorescent proteins

(2014) L. JOOSEN et al.   JOURNAL OF MICROSCOPY

Specialization among Iron-Sulfur Cluster Helicases to Resolve G-quadruplex DNA Structures That Threaten Genomic Stability

(2013) Sanjay Kumar Bharti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Detection of G-quadruplex DNA in mammalian cells

(2013) A. Henderson et al.   NUCLEIC ACIDS RESEARCH

Rapid Global Fitting of Large Fluorescence Lifetime Imaging Microscopy Datasets

(2013) Sean C. Warren et al.   PLoS One

RTEL1 Is a Replisome-Associated Helicase That Promotes Telomere and Genome-Wide Replication

(2013) J.-B. Vannier et al.   SCIENCE

Salphen metal complexes as tunable G-quadruplex binders and optical probes

(2013) Nurul H. Abd Karim et al.   RSC Advances

RTEL1 Dismantles T Loops and Counteracts Telomeric G4-DNA to Maintain Telomere Integrity

(2012) Jean-Baptiste Vannier et al.   CELL

MDC1 and RNF8 function in a pathway that directs BRCA1-dependent localization of PALB2 required for homologous recombination

(2012) F. Zhang et al.   JOURNAL OF CELL SCIENCE

Thioflavin T as an Efficient Inducer and Selective Fluorescent Sensor for the Human Telomeric G-Quadruplex DNA

(2012) Jyotirmayee Mohanty et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Small-molecule–induced DNA damage identifies alternative DNA structures in human genes

(2012) Raphaël Rodriguez et al.   Nature Chemical Biology

DNA secondary structures: stability and function of G-quadruplex structures

(2012) Matthew L. Bochman et al.   NATURE REVIEWS GENETICS

Fixation alters fluorescence lifetime and anisotropy of cells expressing EYFP-tagged serotonin1A receptor

(2011) Sourav Ganguly et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A BEN-domain-containing protein associates with heterochromatin and represses transcription

(2011) K. M. Sathyan et al.   JOURNAL OF CELL SCIENCE

Molecular Basis of Structure–Activity Relationships between Salphen Metal Complexes and Human Telomeric DNA Quadruplexes

(2011) Nancy H. Campbell et al.   JOURNAL OF MEDICINAL CHEMISTRY

A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands

(2011) Deepak Koirala et al.   Nature Chemistry

FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA

(2011) Peter Sarkies et al.   NUCLEIC ACIDS RESEARCH

Early In Vitro Differentiation of Mouse Definitive Endoderm Is Not Correlated with Progressive Maturation of Nuclear DNA Methylation Patterns

(2011) Jian Tajbakhsh et al.   PLoS One

Small-molecule-mediated G-quadruplex isolation from human cells

(2010) Sebastian Müller et al.   Nature Chemistry

Effects of Metal Coordination Geometry on Stabilization of Human Telomeric Quadruplex DNA by Square-Planar and Square-Pyramidal Metal Complexes

(2008) Anna Arola-Arnal et al.   INORGANIC CHEMISTRY

Thioflavin T as a Molecular Rotor: Fluorescent Properties of Thioflavin T in Solvents with Different Viscosity

(2008) Vitali I. Stsiapura et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A Novel Small Molecule That Alters Shelterin Integrity and Triggers a DNA-Damage Response at Telomeres

(2008) Raphaël Rodriguez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FANCJ Helicase Defective in Fanconia Anemia and Breast Cancer Unwinds G-Quadruplex DNA To Defend Genomic Stability

(2008) Y. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY