Ethyl-substitutive Thioflavin T as a highly-specific fluorescence probe for detecting G-quadruplex structure

DNA G-quadruplexes in the human genome: detection, functions and therapeutic potential

(2017) Robert Hänsel-Hertsch et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A versatile nanomachine for the sensitive detection of platelet-derived growth factor-BB utilizing a G-quadruplex-selective iridium(III) complex

(2016) Lihua Lu et al.   BIOSENSORS & BIOELECTRONICS

Quadruplex Turncoats: Cation-Dependent Folding and Stability of Quadruplex-DNA Double Switches

(2016) Eric Largy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A novel transition pathway of ligand-induced topological conversion from hybrid forms to parallel forms of human telomeric G-quadruplexes

(2016) Zi-Fu Wang et al.   NUCLEIC ACIDS RESEARCH

Conjugating a groove-binding motif to an Ir(iii) complex for the enhancement of G-quadruplex probe behavior

(2016) Modi Wang et al.   Chemical Science

Development of a luminescent G-quadruplex-selective iridium(III) complex for the label-free detection of adenosine

(2016) Lihua Lu et al.   Scientific Reports

Selective recognition and stabilization of new ligands targeting the potassium form of the human telomeric G-quadruplex DNA

(2016) Yi-Hwa Lin et al.   Scientific Reports

Recent Developments in G-Quadruplex Probes

(2015) Dik-Lung Ma et al.   CHEMISTRY & BIOLOGY

A Fluorescent Anti-Cancer Agent, 3,6-bis(1-methyl-4-vinylpyridinium) Carbazole Diiodide, Stains G-Quadruplexes in Cells and Inhibits Tumor Growth

(2015) Ting-Yuan Tseng et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Recent Development of G-Quadruplex Probes for Cellular Imaging

(2015) Dik-Lung Ma et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

G-quadruplexes and their regulatory roles in biology

(2015) Daniela Rhodes et al.   NUCLEIC ACIDS RESEARCH

Luminescence switch-on detection of protein tyrosine kinase-7 using a G-quadruplex-selective probe

(2015) Sheng Lin et al.   Chemical Science

Label-free luminescence switch-on detection of hepatitis C virus NS3 helicase activity using a G-quadruplex-selective probe

(2015) Ka-Ho Leung et al.   Chemical Science

KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines

(2015) João Lavrado et al.   Scientific Reports

Molecular Rotor-Based Fluorescent Probe for Selective Recognition of Hybrid G-Quadruplex and as a K+ Sensor

(2014) Lingling Liu et al.   ANALYTICAL CHEMISTRY

RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer

(2014) Andrew L. Wolfe et al.   NATURE

Structural basis for activity of highly efficient RNA mimics of green fluorescent protein

(2014) Katherine Deigan Warner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Thioflavin T as a fluorescence light-up probe for G4 formation

(2014) Amandine Renaud de la Faverie et al.   NUCLEIC ACIDS RESEARCH

Fluorescence Light-Up Probe for Parallel G-Quadruplexes

(2013) Bing Jin et al.   ANALYTICAL CHEMISTRY

Asymmetric Distyrylpyridinium Dyes as Red-Emitting Fluorescent Probes for Quadruplex DNA

(2013) Xiao Xie et al.   CHEMISTRY-A EUROPEAN JOURNAL

Fluorescent probe for visualizing guanine-quadruplex DNA by fluorescence lifetime imaging microscopy

(2013) Ting-Yuan Tseng et al.   JOURNAL OF BIOMEDICAL OPTICS

Crystal Structure of a Promoter Sequence in the B-raf Gene Reveals an Intertwined Dimer Quadruplex

(2013) Dengguo Wei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bulges in G-Quadruplexes: Broadening the Definition of G-Quadruplex-Forming Sequences

(2013) Vineeth Thachappilly Mukundan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Thioflavin T as an Efficient Inducer and Selective Fluorescent Sensor for the Human Telomeric G-Quadruplex DNA

(2012) Jyotirmayee Mohanty et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

G4LDB: a database for discovering and studying G-quadruplex ligands

(2012) Qian Li et al.   NUCLEIC ACIDS RESEARCH

A New Cationic Porphyrin Derivative (TMPipEOPP) with Large Side Arm Substituents: A Highly Selective G-Quadruplex Optical Probe

(2012) Li-Na Zhu et al.   PLoS One

Interaction of G-Quadruplexes with Nonintercalating Duplex-DNA Minor Groove Binding Ligands

(2011) Akash K. Jain et al.   BIOCONJUGATE CHEMISTRY

Translational Repression of the Disintegrin and Metalloprotease ADAM10 by a Stable G-quadruplex Secondary Structure in Its 5′-Untranslated Region

(2011) Sven Lammich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A sequence-specific threading tetra-intercalator with an extremely slow dissociation rate constant

(2011) Garen G. Holman et al.   Nature Chemistry

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

(2011) Shankar Balasubramanian et al.   NATURE REVIEWS DRUG DISCOVERY

TheBCL-25′ Untranslated Region Contains an RNA G-Quadruplex-Forming Motif That Modulates Protein Expression

(2010) Ramla Shahid et al.   BIOCHEMISTRY

An RNA G-Quadruplex Is Essential for Cap-Independent Translation Initiation in Human VEGF IRES

(2010) Mark J. Morris et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

5'-UTR G-quadruplex structures acting as translational repressors

(2010) J.-D. Beaudoin et al.   NUCLEIC ACIDS RESEARCH

Repression of Translation of Human Estrogen Receptor α by G-Quadruplex Formation

(2009) Graham D. Balkwill et al.   BIOCHEMISTRY

Structural polymorphism within a regulatory element of the human KRAS promoter: formation of G4-DNA recognized by nuclear proteins

(2008) Susanna Cogoi et al.   NUCLEIC ACIDS RESEARCH

Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes

(2008) Johanna Eddy et al.   NUCLEIC ACIDS RESEARCH

G-quadruplexes: the beginning and end of UTRs

(2008) Julian Leon Huppert et al.   NUCLEIC ACIDS RESEARCH

Amide bond direction modulates G-quadruplex recognition and telomerase inhibition by 2,6 and 2,7 bis-substituted anthracenedione derivatives

(2007) Giuseppe Zagotto et al.   BIOORGANIC & MEDICINAL CHEMISTRY