Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells

The G-Quadruplex Augments Translation in the 5′ Untranslated Region of Transforming Growth Factor β2

(2013) Prachi Agarwala et al.   BIOCHEMISTRY

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Exploring mRNA 3′-UTR G-quadruplexes: evidence of roles in both alternative polyadenylation and mRNA shortening

(2013) Jean-Denis Beaudoin et al.   NUCLEIC ACIDS RESEARCH

The G4 Genome

(2013) Nancy Maizels et al.   PLoS Genetics

Selective RNA Versus DNA G-Quadruplex Targeting by In Situ Click Chemistry

(2012) Marco Di Antonio et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

COPI transport complexes bind to specific RNAs in neuronal cells

(2012) Adrian G. Todd et al.   HUMAN MOLECULAR GENETICS

A G-Rich element forms a G-quadruplex and regulates BACE1 mRNA alternative splicing

(2012) Jean-François Fisette et al.   JOURNAL OF NEUROCHEMISTRY

An Intramolecular G-Quadruplex Structure Is Required for Binding of Telomeric Repeat-Containing RNA to the Telomeric Protein TRF2

(2012) Giulia Biffi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Experimental approaches to identify cellular G-quadruplex structures and functions

(2012) Marco Di Antonio et al.   METHODS

Small-molecule–induced DNA damage identifies alternative DNA structures in human genes

(2012) Raphaël Rodriguez et al.   Nature Chemical Biology

DNA secondary structures: stability and function of G-quadruplex structures

(2012) Matthew L. Bochman et al.   NATURE REVIEWS GENETICS

The porphyrin TmPyP4 unfolds the extremely stable G-quadruplex in MT3-MMP mRNA and alleviates its repressive effect to enhance translation in eukaryotic cells

(2012) Mark J. Morris et al.   NUCLEIC ACIDS RESEARCH

5'-UTR RNA G-quadruplexes: translation regulation and targeting

(2012) A. Bugaut et al.   NUCLEIC ACIDS RESEARCH

Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells

(2012) Sebastian Müller et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A Sequence-Independent Analysis of the Loop Length Dependence of Intramolecular RNA G-Quadruplex Stability and Topology

(2011) Amy Y. Q. Zhang et al.   BIOCHEMISTRY

Efficient Suppression of Gene Expression by Targeting 5′-UTR-Based RNA Quadruplexes with Bisquinolinium Compounds

(2011) Kangkan Halder et al.   CHEMBIOCHEM

Photoactivated cationic alkyl-substituted porphyrin binding to g4-RNA in the 5′-UTR of KRAS oncogene represses translation

(2011) Mariangela Faudale et al.   CHEMICAL COMMUNICATIONS

The application of DNA and RNA G-quadruplexes to therapeutic medicines

(2011) Gavin W. Collie et al.   CHEMICAL SOCIETY REVIEWS

Human DHX9 helicase preferentially unwinds RNA-containing displacement loops (R-loops) and G-quadruplexes

(2011) Prasun Chakraborty et al.   DNA REPAIR

G–quadruplex RNA structure as a signal for neurite mRNA targeting

(2011) Murugan Subramanian et al.   EMBO REPORTS

Structural Basis of Telomeric RNA Quadruplex−Acridine Ligand Recognition

(2011) Gavin W. Collie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

(2011) Shankar Balasubramanian et al.   NATURE REVIEWS DRUG DISCOVERY

TheBCL-25′ Untranslated Region Contains an RNA G-Quadruplex-Forming Motif That Modulates Protein Expression

(2010) Ramla Shahid et al.   BIOCHEMISTRY

G-quadruplex structures in TP53 intron 3: role in alternative splicing and in production of p53 mRNA isoforms

(2010) Virginie Marcel et al.   CARCINOGENESIS

An RNA G-Quadruplex Is Essential for Cap-Independent Translation Initiation in Human VEGF IRES

(2010) Mark J. Morris et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A G-quadruplex structure within the 5′-UTR of TRF2 mRNA represses translation in human cells

(2010) Dennis Gomez et al.   NUCLEIC ACIDS RESEARCH

A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex

(2010) Gavin W. Collie et al.   NUCLEIC ACIDS RESEARCH

Small molecule-mediated inhibition of translation by targeting a native RNA G-quadruplex

(2010) Anthony Bugaut et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Distinct functions of maternal and somatic Pat1 protein paralogs

(2010) A. Marnef et al.   RNA

Selective Recognition of a DNA G-Quadruplex by an Engineered Antibody†

(2008) Himesh Fernando et al.   BIOCHEMISTRY

G4 Resolvase 1 Binds Both DNA and RNA Tetramolecular Quadruplex with High Affinity and Is the Major Source of Tetramolecular Quadruplex G4-DNA and G4-RNA Resolving Activity in HeLa Cell Lysates

(2008) Steven D. Creacy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Small Molecule That Alters Shelterin Integrity and Triggers a DNA-Damage Response at Telomeres

(2008) Raphaël Rodriguez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes

(2008) Johanna Eddy et al.   NUCLEIC ACIDS RESEARCH

G-quadruplexes: the beginning and end of UTRs

(2008) Julian Leon Huppert et al.   NUCLEIC ACIDS RESEARCH