Specialization among Iron-Sulfur Cluster Helicases to Resolve G-quadruplex DNA Structures That Threaten Genomic Stability

FANCJ couples replication past natural fork barriers with maintenance of chromatin structure

(2013) Rebekka A. Schwab et al.   JOURNAL OF CELL BIOLOGY

RTEL1 Dismantles T Loops and Counteracts Telomeric G4-DNA to Maintain Telomere Integrity

(2012) Jean-Baptiste Vannier et al.   CELL

Identification and Biochemical Characterization of a Novel Mutation inDDX11Causing Warsaw Breakage Syndrome

(2012) José-Mario Capo-Chichi et al.   HUMAN MUTATION

The Q Motif of Fanconi Anemia Group J Protein (FANCJ) DNA Helicase Regulates Its Dimerization, DNA Binding, and DNA Repair Function

(2012) Yuliang Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small-molecule–induced DNA damage identifies alternative DNA structures in human genes

(2012) Raphaël Rodriguez et al.   Nature Chemical Biology

DNA secondary structures: stability and function of G-quadruplex structures

(2012) Matthew L. Bochman et al.   NATURE REVIEWS GENETICS

Cross talk between the nuclease and helicase activities of Dna2: role of an essential iron–sulfur cluster domain

(2012) Subhash Pokharel et al.   NUCLEIC ACIDS RESEARCH

Development of a high-throughput G4-FID assay for screening and evaluation of small molecules binding quadruplex nucleic acid structures

(2011) Eric Largy et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces cerevisiae Pif1 DNA Helicase

(2011) Katrin Paeschke et al.   CELL

G-quadruplex-induced instability during leading-strand replication

(2011) Judith Lopes et al.   EMBO JOURNAL

Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome

(2011) Avvaru N Suhasini et al.   EMBO JOURNAL

Biochemical Characterization of Warsaw Breakage Syndrome Helicase

(2011) Yuliang Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RecQ helicases in DNA double strand break repair and telomere maintenance

(2011) Dharmendra Kumar Singh et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

(2011) Shankar Balasubramanian et al.   NATURE REVIEWS DRUG DISCOVERY

FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA

(2011) Peter Sarkies et al.   NUCLEIC ACIDS RESEARCH

G4 Resolvase 1 tightly binds and unwinds unimolecular G4-DNA

(2011) Banabihari Giri et al.   NUCLEIC ACIDS RESEARCH

Warsaw Breakage Syndrome, a Cohesinopathy Associated with Mutations in the XPD Helicase Family Member DDX11/ChlR1

(2010) Petra van der Lelij et al.   AMERICAN JOURNAL OF HUMAN GENETICS

G-quadruplex nucleic acids and human disease

(2010) Yuliang Wu et al.   FEBS Journal

Telomeres: Structures in need of unwinding

(2010) Katrin Paeschke et al.   FEBS LETTERS

Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion

(2010) A. R. Leman et al.   JOURNAL OF CELL SCIENCE

Small-molecule-mediated G-quadruplex isolation from human cells

(2010) Sebastian Müller et al.   Nature Chemistry

Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae

(2010) Aurèle Piazza et al.   NUCLEIC ACIDS RESEARCH

Telomeres do the (un)twist: Helicase actions at chromosome termini

(2009) Alejandro Chavez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Predicting and understanding the stability of G-quadruplexes

(2009) Oliver Stegle et al.   BIOINFORMATICS

Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential

(2009) Jay E. Johnson et al.   NUCLEIC ACIDS RESEARCH

The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo

(2009) Cyril Ribeyre et al.   PLoS Genetics

FANCJ Is a Structure-specific DNA Helicase Associated with the Maintenance of Genomic G/C Tracts

(2008) Timothy B. C. London et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Small Molecule That Alters Shelterin Integrity and Triggers a DNA-Damage Response at Telomeres

(2008) Raphaël Rodriguez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FANCJ Helicase Defective in Fanconia Anemia and Breast Cancer Unwinds G-Quadruplex DNA To Defend Genomic Stability

(2008) Y. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Crystal Structure of the FeS Cluster–Containing Nucleotide Excision Repair Helicase XPD

(2008) Stefanie C Wolski et al.   PLOS BIOLOGY