Continuous microfluidic 3D focusing enabling microflow cytometry for single-cell analysis

Virtual optofluidic time-stretch quantitative phase imaging

(2020) Haochen Yan et al.   APL Photonics

Circular-channel particle focuser utilizing viscoelastic focusing

(2019) Nan Xiang et al.   Microfluidics and Nanofluidics

Occurrence of the potent mutagens 2- nitrobenzanthrone and 3-nitrobenzanthrone in fine airborne particles

(2019) Aldenor G. Santos et al.   Scientific Reports

An automated Raman-based platform for the sorting of live cells by functional properties

(2019) Kang Soo Lee et al.   Nature Microbiology

Enhancement in acoustic focusing of micro and nanoparticles by thinning a microfluidic device

(2019) Nobutoshi Ota et al.   Royal Society Open Science

Elasto-inertial particle focusing in 3D-printed microchannels with unconventional cross sections

(2019) Wenlai Tang et al.   Microfluidics and Nanofluidics

Dean-flow-coupled elasto-inertial particle and cell focusing in symmetric serpentine microchannels

(2019) Dan Yuan et al.   Microfluidics and Nanofluidics

λ-DNA- and Aptamer-Mediated Sorting and Analysis of Extracellular Vesicles

(2019) Chao Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intelligent Image De‐Blurring for Imaging Flow Cytometry

(2019) Fangzheng Zhang et al.   CYTOMETRY PART A

A Spiral-Helix (3D) Tubing Array That Ensures Ultrahigh-Throughput Single-Cell Sampling

(2019) Xing Wei et al.   ANALYTICAL CHEMISTRY

In Silico Labeling: Predicting Fluorescent Labels in Unlabeled Images

(2018) Eric M. Christiansen et al.   CELL

Dean flow assisted cell ordering system for lipid profiling in single-cells using mass spectrometry

(2018) Qiushi Huang et al.   CHEMICAL COMMUNICATIONS

Recent progress of particle migration in viscoelastic fluids

(2018) Dan Yuan et al.   LAB ON A CHIP

Deep learning massively accelerates super-resolution localization microscopy

(2018) Wei Ouyang et al.   NATURE BIOTECHNOLOGY

Tunable particle separation in a hybrid dielectrophoresis (DEP)- inertial microfluidic device

(2018) Jun Zhang et al.   SENSORS AND ACTUATORS B-CHEMICAL

Magnetic activated cell sorting (MACS) pipette tip for immunomagnetic bacteria separation

(2018) Sein Oh et al.   SENSORS AND ACTUATORS B-CHEMICAL

Ultrafast confocal fluorescence microscopy beyond the fluorescence lifetime limit

(2018) Hideharu Mikami et al.   Optica

Nanoporous membrane device for ultra high heat flux thermal management

(2018) Daniel F. Hanks et al.   Microsystems & Nanoengineering

Intelligent Image-Activated Cell Sorting

(2018) Nao Nitta et al.   CELL

Dielectrophoresis-based 3D-focusing of microscale entities in microfluidic devices

(2018) Fadi Alnaimat et al.   CYTOMETRY PART A

Combined CD25, CD64, and CD69 biomarker panel for flow cytometry diagnosis of sepsis

(2018) Yun Zhou et al.   TALANTA

Application of flow cytometry to wine microorganisms

(2017) Cédric Longin et al.   FOOD MICROBIOLOGY

Particle manipulations in non-Newtonian microfluidics: A review

(2017) Xinyu Lu et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Coplanar electrode microfluidic chip enabling accurate sheathless impedance cytometry

(2017) Adele De Ninno et al.   LAB ON A CHIP

On-chip cell sorting by high-speed local-flow control using dual membrane pumps

(2017) Shinya Sakuma et al.   LAB ON A CHIP

Label-free detection of aggregated platelets in blood by machine-learning-aided optofluidic time-stretch microscopy

(2017) Yiyue Jiang et al.   LAB ON A CHIP

A deep learning and novelty detection framework for rapid phenotyping in high-content screening

(2017) Christoph Sommer et al.   MOLECULAR BIOLOGY OF THE CELL

Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance

(2017) Sydney M. Shaffer et al.   NATURE

Sheathless Microflow Cytometry Using Viscoelastic Fluids

(2017) Mohammad Asghari et al.   Scientific Reports

High performance micro-flow cytometer based on optical fibres

(2017) S. Etcheverry et al.   Scientific Reports

Computational cell analysis for label-free detection of cell properties in a microfluidic laminar flow

(2016) Alex Ce Zhang et al.   ANALYST

Viscoelastic Separation of Particles by Size in Straight Rectangular Microchannels: A Parametric Study for a Refined Understanding

(2016) Di Li et al.   ANALYTICAL CHEMISTRY

Sheathless Focusing and Separation of Diverse Nanoparticles in Viscoelastic Solutions with Minimized Shear Thinning

(2016) Chao Liu et al.   ANALYTICAL CHEMISTRY

Dielectric model for Chinese hamster ovary cells obtained by dielectrophoresis cytometry

(2016) E. Salimi et al.   Biomicrofluidics

Hybrid microfluidics combined with active and passive approaches for continuous cell separation

(2016) Sheng Yan et al.   ELECTROPHORESIS

Single-layer microfluidic device to realize hydrodynamic 3D flow focusing

(2016) Gangadhar Eluru et al.   LAB ON A CHIP

High accuracy particle analysis using sheathless microfluidic impedance cytometry

(2016) Daniel Spencer et al.   LAB ON A CHIP

Continuous plasma extraction under viscoelastic fluid in a straight channel with asymmetrical expansion–contraction cavity arrays

(2016) Dan Yuan et al.   LAB ON A CHIP

Review: imaging technologies for flow cytometry

(2016) Yuanyuan Han et al.   LAB ON A CHIP

Fundamentals and applications of inertial microfluidics: a review

(2016) Jun Zhang et al.   LAB ON A CHIP

Drug sensitivity of single cancer cells is predicted by changes in mass accumulation rate

(2016) Mark M Stevens et al.   NATURE BIOTECHNOLOGY

High-throughput measurement of single-cell growth rates using serial microfluidic mass sensor arrays

(2016) Nathan Cermak et al.   NATURE BIOTECHNOLOGY

High-throughput label-free image cytometry and image-based classification of live Euglena gracilis

(2016) Cheng Lei et al.   Biomedical Optics Express

Size-Based Separation of Particles and Cells Utilizing Viscoelastic Effects in Straight Microchannels

(2015) Chao Liu et al.   ANALYTICAL CHEMISTRY

Acoustofluidic Fluorescence Activated Cell Sorter

(2015) Ahmad Ahsan Nawaz et al.   ANALYTICAL CHEMISTRY

Dean-flow-coupled elasto-inertial three-dimensional particle focusing under viscoelastic flow in a straight channel with asymmetrical expansion–contraction cavity arrays

(2015) D. Yuan et al.   Biomicrofluidics

3D hydrodynamic focusing microfluidics for emerging sensing technologies

(2015) Michael A. Daniele et al.   BIOSENSORS & BIOELECTRONICS

A microfluidic dual-well device for high-throughput single-cell capture and culture

(2015) Ching-Hui Lin et al.   LAB ON A CHIP

Fabrication of 3D high aspect ratio PDMS microfluidic networks with a hybrid stamp

(2015) Yu-Chun Kung et al.   LAB ON A CHIP

Deep learning

(2015) Yann LeCun et al.   NATURE

Real-time deformability cytometry: on-the-fly cell mechanical phenotyping

(2015) Oliver Otto et al.   NATURE METHODS

A hybrid dielectrophoretic and hydrophoretic microchip for particle sorting using integrated prefocusing and sorting steps

(2014) Sheng Yan et al.   ELECTROPHORESIS

Two-dimensional acoustic particle focusing enables sheathless chip Coulter counter with planar electrode configuration

(2014) Carl Grenvall et al.   LAB ON A CHIP

Isolating plasma from blood using a dielectrophoresis-active hydrophoretic device

(2014) Sheng Yan et al.   LAB ON A CHIP

Standing surface acoustic wave (SSAW)-based microfluidic cytometer

(2014) Yuchao Chen et al.   LAB ON A CHIP

Straightforward 3D hydrodynamic focusing in femtosecond laser fabricated microfluidic channels

(2014) Petra Paiè et al.   LAB ON A CHIP

A constriction channel based microfluidic system enabling continuous characterization of cellular instantaneous Young's modulus

(2014) Y.N. Luo et al.   SENSORS AND ACTUATORS B-CHEMICAL

Pulsed Laser Activated Cell Sorting with Three Dimensional Sheathless Inertial Focusing

(2014) Yue Chen et al.   Small

Inertio-elastic focusing of bioparticles in microchannels at high throughput

(2014) Eugene J. Lim et al.   Nature Communications

Micro flow cytometer with self-aligned 3D hydrodynamic focusing

(2014) Genni Testa et al.   Biomedical Optics Express

Real-time control of inertial focusing in microfluidics using dielectrophoresis (DEP)

(2014) Jun Zhang et al.   RSC Advances

On-chip high-throughput manipulation of particles in a dielectrophoresis-active hydrophoretic focuser

(2014) Sheng Yan et al.   Scientific Reports

Label-Free Cancer Cell Separation from Human Whole Blood Using Inertial Microfluidics at Low Shear Stress

(2013) Myung Gwon Lee et al.   ANALYTICAL CHEMISTRY

Differential electronic detector to monitor apoptosis using dielectrophoresis-induced translation of flowing cells (dielectrophoresis cytometry)

(2013) Marija Nikolic-Jaric et al.   Biomicrofluidics

Size-based hydrodynamic rare tumor cell separation in curved microfluidic channels

(2013) Jiashu Sun et al.   Biomicrofluidics

Microfluidic cell culture

(2013) Matthias Mehling et al.   CURRENT OPINION IN BIOTECHNOLOGY

Design rules for size-based cell sorting and sheathless cell focusing by hydrophoresis

(2013) Seungjeong Song et al.   JOURNAL OF CHROMATOGRAPHY A

Rapid dielectrophoretic characterization of single cells using the dielectrophoretic spring

(2013) Hao-Wei Su et al.   LAB ON A CHIP

Pinched-flow hydrodynamic stretching of single-cells

(2013) Jaideep S. Dudani et al.   LAB ON A CHIP

Electrical measurement of red blood cell deformability on a microfluidic device

(2013) Yi Zheng et al.   LAB ON A CHIP

Microstructure-induced helical vortices allow single-stream and long-term inertial focusing

(2013) Aram J. Chung et al.   LAB ON A CHIP

Sub-micrometer-precision, three-dimensional (3D) hydrodynamic focusing via “microfluidic drifting”

(2013) Ahmad Ahsan Nawaz et al.   LAB ON A CHIP

Size-selective collection of circulating tumor cells using Vortex technology

(2013) Elodie Sollier et al.   LAB ON A CHIP

Digitally synthesized beat frequency multiplexing for sub-millisecond fluorescence microscopy

(2013) Eric D. Diebold et al.   Nature Photonics

High-speed ultrawideband photonically enabled compressed sensing of sparse radio frequency signals

(2013) Bryan T. Bosworth et al.   OPTICS LETTERS

Characterizing deformability and surface friction of cancer cells

(2013) S. Byun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative Diagnosis of Malignant Pleural Effusions by Single-Cell Mechanophenotyping

(2013) H. T. K. Tse et al.   Science Translational Medicine

DNA-based highly tunable particle focuser

(2013) Kyowon Kang et al.   Nature Communications

Particle migration and single-line particle focusing in microscale pipe flow of viscoelastic fluids

(2013) Kyung Won Seo et al.   RSC Advances

Multiplex Particle Focusing via Hydrodynamic Force in Viscoelastic Fluids

(2013) Doo Jin Lee et al.   Scientific Reports

Microfluidics-Based Assessment of Cell Deformability

(2012) Andrea Adamo et al.   ANALYTICAL CHEMISTRY

Cell Stretching Measurement Utilizing Viscoelastic Particle Focusing

(2012) Sukgyun Cha et al.   ANALYTICAL CHEMISTRY

An integrated, multiparametric flow cytometry chip using “microfluidic drifting” based three-dimensional hydrodynamic focusing

(2012) Xiaole Mao et al.   Biomicrofluidics

Microfluidic single cell analysis: from promise to practice

(2012) Véronique Lecault et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

High-yield cell ordering and deterministic cell-in-droplet encapsulation using Dean flow in a curved microchannel

(2012) Evelien W. M. Kemna et al.   LAB ON A CHIP

Lateral migration and focusing of colloidal particles and DNA molecules under viscoelastic flow

(2012) Jae Young Kim et al.   LAB ON A CHIP

Single channel layer, single sheath-flow inlet microfluidic flow cytometer with three-dimensional hydrodynamic focusing

(2012) Shiang-Chi Lin et al.   LAB ON A CHIP

Double spiral microchannel for label-free tumor cell separation and enrichment

(2012) Jiashu Sun et al.   LAB ON A CHIP

Direct observation of mammalian cell growth and size regulation

(2012) Sungmin Son et al.   NATURE METHODS

Hydrodynamic stretching of single cells for large population mechanical phenotyping

(2012) D. R. Gossett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-throughput single-microparticle imaging flow analyzer

(2012) K. Goda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrodynamic focusing for impedance-based detection of specifically bound microparticles and cells: Implications of fluid dynamics on tunable sensitivity

(2012) Gusphyl A. Justin et al.   SENSORS AND ACTUATORS B-CHEMICAL

Review Article: Recent advancements in optofluidic flow cytometer

(2011) Sung Hwan Cho et al.   Biomicrofluidics

Microfluidics for single cell analysis

(2011) Huabing Yin et al.   CURRENT OPINION IN BIOTECHNOLOGY

Three-dimensional continuous particle focusing in a microfluidic channel via standing surface acoustic waves (SSAW)

(2011) Jinjie Shi et al.   LAB ON A CHIP

High-throughput cell cycle synchronization using inertial forces in spiral microchannels

(2011) Wong Cheng Lee et al.   LAB ON A CHIP

Parameters affecting the shape of a hydrodynamically focused stream

(2011) Mansoor Nasir et al.   Microfluidics and Nanofluidics

High-throughput analysis of single hematopoietic stem cell proliferation in microfluidic cell culture arrays

(2011) Véronique Lecault et al.   NATURE METHODS

Microscale acoustofluidics: Microfluidics driven via acoustics and ultrasonics

(2011) James Friend et al.   REVIEWS OF MODERN PHYSICS

Microfluidic Devices for Blood Fractionation

(2011) Han Wei Hou et al.   Micromachines

Particle Focusing in Staged Inertial Microfluidic Devices for Flow Cytometry

(2010) John Oakey et al.   ANALYTICAL CHEMISTRY

Microfluidic Platforms for Single-Cell Analysis

(2010) Richard N. Zare et al.   Annual Review of Biomedical Engineering

Microfluidic impedance-based flow cytometry

(2010) Karen C. Cheung et al.   CYTOMETRY PART A

Inertial separation in a contraction–expansion array microchannel

(2010) Myung Gwon Lee et al.   JOURNAL OF CHROMATOGRAPHY A

Sheathless elasto-inertial particle focusing and continuous separation in a straight rectangular microchannel

(2010) Seungyoung Yang et al.   LAB ON A CHIP

Particle focusing in microfluidic devices

(2010) Xiangchun Xuan et al.   Microfluidics and Nanofluidics

Using buoyant mass to measure the growth of single cells

(2010) Michel Godin et al.   NATURE METHODS

Synthetic biology: applications come of age

(2010) Ahmad S. Khalil et al.   NATURE REVIEWS GENETICS

Single cell analysis: the new frontier in ‘omics’

(2010) Daojing Wang et al.   TRENDS IN BIOTECHNOLOGY

Tumor heterogeneity: Causes and consequences

(2009) Andriy Marusyk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Inertial microfluidics for sheath-less high-throughput flow cytometry

(2009) Ali Asgar S. Bhagat et al.   BIOMEDICAL MICRODEVICES

Hydrodynamic focusing of conducting fluids for conductivity-based biosensors

(2009) Mansoor Nasir et al.   BIOSENSORS & BIOELECTRONICS

Moving Pictures: Imaging Flow Cytometry for Drug Development

(2009) Gary Elliott   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Three-dimensional hydrodynamic focusing with a single sheath flow in a single-layer microfluidic device

(2009) Myung Gwon Lee et al.   LAB ON A CHIP

Inertial microfluidics

(2009) Dino Di Carlo   LAB ON A CHIP

Inertial microfluidics for continuous particle separation in spiral microchannels

(2009) Sathyakumar S. Kuntaegowdanahalli et al.   LAB ON A CHIP

Sheathless inertial cell ordering for extreme throughput flow cytometry

(2009) Soojung Claire Hur et al.   LAB ON A CHIP

Tracking lineages of single cells in lines using a microfluidic device

(2009) A. C. Rowat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Measurement of mass, density, and volume during the cell cycle of yeast

(2009) A. K. Bryan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optically Coated Mirror-Embedded Microchannel to Measure Hydrophoretic Particle Ordering in Three Dimensions

(2009) Sungyoung Choi et al.   Small

Hydrophoretic Sorting of Micrometer and Submicrometer Particles Using Anisotropic Microfluidic Obstacles

(2008) Sungyoung Choi et al.   ANALYTICAL CHEMISTRY

Nuclear Shape, Mechanics, and Mechanotransduction

(2008) Kris Noel Dahl et al.   CIRCULATION RESEARCH

A Subset of Human Limbal Epithelial Cells With Greater Nucleus-to-Cytoplasm Ratio Expressing High Levels of p63 Possesses Slow-Cycling Property

(2008) Parthasarathy Arpitha et al.   CORNEA

Multispectral imaging of hematopoietic cells: Where flow meets morphology

(2008) Kathleen E. McGrath et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Continuous particle separation in spiral microchannels using dean flows and differential migration

(2008) Ali Asgar S. Bhagat et al.   LAB ON A CHIP

Microvortex for focusing, guiding and sorting of particles

(2008) Chia-Hsien Hsu et al.   LAB ON A CHIP

A three-dimensional (3D) particle focusing channel using the positive dielectrophoresis (pDEP) guided by a dielectric structure between two planar electrodes

(2008) Hyunjung Chu et al.   LAB ON A CHIP

Three-dimensional hydrodynamic focusing in a microfluidic Coulter counter

(2008) R. Scott et al.   REVIEW OF SCIENTIFIC INSTRUMENTS