4.7 Article

Multiplex Particle Focusing via Hydrodynamic Force in Viscoelastic Fluids

Journal

SCIENTIFIC REPORTS
Volume 3, Issue -, Pages -

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/srep03258

Keywords

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Funding

  1. Basic Science Research Program through the National Research Foundation of Korea (NRF)
  2. Ministry of Education, Science and Technology [2013R1A1A2059827]
  3. Korea Science and Engineering Foundation (KOSEF)
  4. Korean government (MEST) through the Intelligent Textile System Research Center (ITRC) [R11-2005-065]
  5. National Research Foundation of Korea [2013R1A1A2059827] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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We introduce a multiplex particle focusing phenomenon that arises from the hydrodynamic interaction between the viscoelastic force and the Dean drag force in a microfluidic device. In a confined microchannel, the first normal stress difference of viscoelastic fluids results in a lateral migration of suspended particles. Such a viscoelastic force was harnessed to focus different sized particles in the middle of a microchannel, and spiral channel geometry was also considered in order to take advantage of the counteracting force, Dean drag force that induces particle migration in the outward direction. For theoretical understanding, we performed a numerical analysis of viscoelastic fluids in the spiral microfluidic channel. From these results, a concept of the 'Dean-coupled Elasto-inertial Focusing band (DEF)' was proposed. This study provides in-depth physical insight into the multiplex focusing of particles that can open a new venue for microfluidic particle dynamics for a concrete high throughput platform at microscale.

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