Connection between the Altered HDL Antioxidant and Anti-Inflammatory Properties and the Risk to Develop Alzheimer’s Disease: A Narrative Review

Dysfunctional High-Density Lipoproteins Are Associated With a Greater Incidence of Acute Coronary Syndrome in a Population at High Cardiovascular Risk

(2020) María Trinidad Soria-Florido et al.   CIRCULATION

Development, optimization and validation of an absolute specific assay for active myeloperoxidase (MPO) and its application in a clinical context: role of MPO specific activity in coronary artery disease

(2020) Alessandro Trentini et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Association between serum amyloid A levels and coronary heart disease: a systematic review and meta-analysis of 26 studies

(2020) Jielin Zhou et al.   INFLAMMATION RESEARCH

High-Density Lipoprotein (HDL) Inhibits Serum Amyloid A (SAA)-Induced Vascular and Renal Dysfunctions in Apolipoprotein E-Deficient Mice

(2020) Xiaoping Cai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Changes in Serum Amyloid A (SAA) and 8-OHdG in Patients with Senile Early Cognitive Impairment

(2020) Xiaohong Cao et al.   MEDICAL SCIENCE MONITOR

Inflammation in Neurological Disorders: The Thin Boundary Between Brain and Periphery

(2020) Carlo Cervellati et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of Selenoproteins in Redox Regulation of Signaling and the Antioxidant System: A Review

(2020) Ying Zhang et al.   Antioxidants

Extracellular Glutathione Peroxidase GPx3 and Its Role in Cancer

(2020) Caroline Chang et al.   Cancers

Neutrophil activation in Alzheimer’s disease and mild cognitive impairment: A systematic review and meta-analysis of protein markers in blood and cerebrospinal fluid

(2020) Che-Yuan Wu et al.   AGEING RESEARCH REVIEWS

Structural Basis for Vital Function and Malfunction of Serum Amyloid A: an Acute-Phase Protein that Wears Hydrophobicity on Its Sleeve

(2020) Olga Gursky   Current Atherosclerosis Reports

HDL Proteome and Alzheimer’s Disease: Evidence of a Link

(2020) Judit Marsillach et al.   Antioxidants

Cardioprotective Properties Of Hdl: Structural And Functional Considerations

(2019) E. Pappa et al.   CURRENT MEDICINAL CHEMISTRY

HDL and Reverse Cholesterol Transport

(2019) Mireille Ouimet et al.   CIRCULATION RESEARCH

Role of serum amyloid A in atherosclerosis

(2019) Preetha Shridas et al.   CURRENT OPINION IN LIPIDOLOGY

Molecular mechanisms underlying protective role of quercetin in attenuating Alzheimer's disease

(2019) Elizabeta Zaplatic et al.   LIFE SCIENCES

Evaluating the link between Paraoxonase-1 levels and Alzheimer's disease development

(2019) Carlo Cervellati et al.   MINERVA MEDICA

Paraoxonase-1 activities in individuals with different HDL circulating levels: Implication in reverse cholesterol transport and early vascular damage

(2019) Carlo Cervellati et al.   ATHEROSCLEROSIS

Myeloperoxidase – A bridge linking inflammation and oxidative stress with cardiovascular disease

(2019) Gjin Ndrepepa   CLINICA CHIMICA ACTA

HDL from an Alzheimerʼs disease perspective

(2019) Emily B. Button et al.   CURRENT OPINION IN LIPIDOLOGY

ABCA1- and ABCG1-mediated cholesterol efflux capacity of cerebrospinal fluid is impaired in Alzheimer’s disease

(2019) Cinzia Marchi et al.   JOURNAL OF LIPID RESEARCH

Serum amyloid A1 is involved in amyloid plaque aggregation and memory decline in amyloid beta abundant condition

(2019) Soyoung Jang et al.   TRANSGENIC RESEARCH

Myeloperoxidase Deficiency Inhibits Cognitive Decline in the 5XFAD Mouse Model of Alzheimer’s Disease

(2019) Rotem Volkman et al.   Frontiers in Neuroscience

Serum Amyloid A Is an Exchangeable Apolipoprotein

(2018) Patricia G. Wilson et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Dysfunctional HDL as a therapeutic target for atherosclerosis prevention

(2018) Alice Ossoli et al.   CURRENT MEDICINAL CHEMISTRY

Oxidative stress in autoimmune rheumatic diseases

(2018) Miranda J. Smallwood et al.   FREE RADICAL BIOLOGY AND MEDICINE

High-density lipoprotein inhibits serum amyloid A-mediated reactive-oxygen species generation and NLRP3 inflammasome activation

(2018) Preetha Shridas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Different Associations of Plasma Biomarkers in Alzheimer's Disease, Mild Cognitive Impairment, Vascular Dementia, and Ischemic Stroke

(2018) Jingwei Shang et al.   Journal of Clinical Neurology

Serum amyloid A primes microglia for ATP-dependent interleukin-1β release

(2018) Laura Facci et al.   Journal of Neuroinflammation

Peripheral Oxidative Stress Biomarkers in Mild Cognitive Impairment and Alzheimer's Disease

(2018) Larissa Lobo Torres et al.   JOURNAL OF ALZHEIMERS DISEASE

Diabetes and Hypercholesterolemia Increase Blood-Brain Barrier Permeability and Brain Amyloid Deposition: Beneficial Effects of the LpPLA2 Inhibitor Darapladib

(2018) Nimish K. Acharya et al.   JOURNAL OF ALZHEIMERS DISEASE

Increased Myeloperoxidase Plasma Levels in Patients with Alzheimer's Disease

(2018) Stergios Tzikas et al.   JOURNAL OF ALZHEIMERS DISEASE

Serum amyloid A – a review

(2018) George H. Sack   MOLECULAR MEDICINE

Blood-brain barrier breakdown, neuroinflammation, and cognitive decline in older adults

(2018) Gene L. Bowman et al.   Alzheimers & Dementia

Distribution of Paraoxonase-1 (PON-1) and Lipoprotein Phospholipase A2 (Lp-PLA2) across Lipoprotein Subclasses in Subjects with Type 2 Diabetes

(2018) Angelina Passaro et al.   Oxidative Medicine and Cellular Longevity

Blood-Derived Plasma Protein Biomarkers for Alzheimer’s Disease in Han Chinese

(2018) Zaohuo Cheng et al.   Frontiers in Aging Neuroscience

Quantifying HDL proteins by mass spectrometry: how many proteins are there and what are their functions?

(2017) Baohai Shao et al.   Expert Review of Proteomics

Updating the Evidence on the Association between Serum Cholesterol and Risk of Late-Life Dementia: Review and Meta-Analysis

(2017) Kaarin J. Anstey et al.   JOURNAL OF ALZHEIMERS DISEASE

Plasma cholesterol homeostasis, HDL remodeling and function during the acute phase reaction

(2017) Francesca Zimetti et al.   JOURNAL OF LIPID RESEARCH

Apolipoprotein A-II alters the proteome of human lipoproteins and enhances cholesterol efflux from ABCA1

(2017) John T. Melchior et al.   JOURNAL OF LIPID RESEARCH

Evacetrapib and Cardiovascular Outcomes in High-Risk Vascular Disease

(2017) A. Michael Lincoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lactonase Activity and Lipoprotein-Phospholipase A2 as Possible Novel Serum Biomarkers for the Differential Diagnosis of Autism Spectrum Disorders and Rett Syndrome: Results from a Pilot Study

(2017) Joussef Hayek et al.   Oxidative Medicine and Cellular Longevity

The association of MPO gene promoter polymorphisms with Alzheimer’s disease risk in Chinese Han population

(2017) Wenzhen Ji et al.   Oncotarget

Lipoprotein-associated Phospholipase A2 Is Associated with Risk of Mild Cognitive Impairment in Chinese Patients with Type 2 Diabetes

(2017) Rongrong Cai et al.   Scientific Reports

SR-BI Mediated Transcytosis of HDL in Brain Microvascular Endothelial Cells Is Independent of Caveolin, Clathrin, and PDZK1

(2017) Karen Y. Fung et al.   Frontiers in Physiology

Expression and Differential Responsiveness of Central Nervous System Glial Cell Populations to the Acute Phase Protein Serum Amyloid A

(2017) Massimo Barbierato et al.   Scientific Reports

Paraoxonases-1, -2 and -3: What are their functions?

(2016) Clement E. Furlong et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Inhibition of myeloperoxidase oxidant production by N-acetyl lysyltyrosylcysteine amide reduces brain damage in a murine model of stroke

(2016) Guoliang Yu et al.   Journal of Neuroinflammation

Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More

(2016) Lucio G. Costa et al.   Oxidative Medicine and Cellular Longevity

Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

(2016) Y. Iturria-Medina et al.   Nature Communications

Aging‐Related Decline of Glutathione Peroxidase 3 and Risk of Cardiovascular Events in Patients With Atrial Fibrillation

(2016) Daniele Pastori et al.   Journal of the American Heart Association

Paraoxonase 1 and HDL maturation

(2015) Alejandro Gugliucci et al.   CLINICA CHIMICA ACTA

PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis

(2015) Diana M. Shih et al.   FASEB JOURNAL

Serum Amyloid A Receptor Blockade and Incorporation into High-Density Lipoprotein Modulates Its Pro-Inflammatory and Pro-Thrombotic Activities on Vascular Endothelial Cells

(2015) Belal Chami et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Serum amyloid A impairs the antiinflammatory properties of HDL

(2015) Chang Yeop Han et al.   JOURNAL OF CLINICAL INVESTIGATION

Paraoxonase-3 Is Depleted from the High-Density Lipoproteins of Autoimmune Disease Patients with Subclinical Atherosclerosis

(2015) Judit Marsillach et al.   JOURNAL OF PROTEOME RESEARCH

Dysfunctional HDL and atherosclerotic cardiovascular disease

(2015) Robert S. Rosenson et al.   Nature Reviews Cardiology

Lipoprotein-associated phospholipase A2 and risk of dementia in the Cardiovascular Health Study

(2014) Annette L. Fitzpatrick et al.   ATHEROSCLEROSIS

HDL and cholesterol handling in the brain

(2014) C. Vitali et al.   CARDIOVASCULAR RESEARCH

Neuroprotection by Association of Palmitoylethanolamide with Luteolin in Experimental Alzheimer’s Disease Models: The Control of Neuroinflammation

(2014) Irene Paterniti et al.   CNS & Neurological Disorders-Drug Targets

Flow-mediated dilation, carotid wall thickness and HDL function in subjects with hyperalphalipoproteinemia

(2014) G.B. Vigna et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Selenium-Enriched Foods Are More Effective at Increasing Glutathione Peroxidase (GPx) Activity Compared with Selenomethionine: A Meta-Analysis

(2014) Emma Bermingham et al.   Nutrients

The Roles of Biomarkers of Oxidative Stress and Antioxidant in Alzheimer’s Disease: A Systematic Review

(2014) Ya-Ting Chang et al.   Biomed Research International

Analysis of 27 vascular-related proteins reveals that NT-proBNP is a potential biomarker for Alzheimer's disease and mild cognitive impairment: A pilot-study

(2013) Josef Marksteiner et al.   EXPERIMENTAL GERONTOLOGY

Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex

(2013) Ying Huang et al.   JOURNAL OF CLINICAL INVESTIGATION

Myeloperoxidase-Derived Oxidants Induce Blood-Brain Barrier Dysfunction In Vitro and In Vivo

(2013) Andreas Üllen et al.   PLoS One

Plasma Amyloid-β as a Predictor of Dementia and Cognitive Decline

(2012) Alain Koyama et al.   ARCHIVES OF NEUROLOGY

Biomarkers for Insulin Resistance and Inflammation and the Risk for All-Cause Dementia and Alzheimer Disease

(2012) Thomas M. van Himbergen   ARCHIVES OF NEUROLOGY

Glutathione peroxidases

(2012) Regina Brigelius-Flohé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

PON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell death

(2012) E-M Schweikert et al.   CELL DEATH AND DIFFERENTIATION

Novel Biological Functions of High-Density Lipoprotein Cholesterol

(2012) Chieko Mineo et al.   CIRCULATION RESEARCH

Monocyte chemoattractant protein-1 and paraoxonase-1 and 3 levels in patients with sepsis treated in an intensive care unit: a preliminary report

(2012) Teresa Sans et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Plasma oxidative stress parameters in men and women with early stage Alzheimer type dementia

(2012) M.C. Puertas et al.   EXPERIMENTAL GERONTOLOGY

Low Serum Glutathione Peroxidase Activity Is Associated with Increased Cardiovascular Mortality in Individuals with Low HDLc’s

(2012) Brian Buijsse et al.   PLoS One

Lipoprotein Phospholipase A2 and Cerebral Microbleeds in the Framingham Heart Study

(2012) José Rafael Romero et al.   STROKE

Plasma lipoprotein-associated phospholipase A2 activity in Alzheimer's disease, amnestic mild cognitive impairment, and cognitively healthy elderly subjects: a cross-sectional study

(2012) Julie E Davidson et al.   Alzheimers Research & Therapy

Serum paraoxonase-3 concentration is associated with insulin sensitivity in peripheral artery disease and with inflammation in coronary artery disease

(2011) Anna Rull et al.   ATHEROSCLEROSIS

Serum paraoxonase-3 concentration is associated with the severity of hepatic impairment in patients with chronic liver disease

(2011) Anabel García-Heredia et al.   CLINICAL BIOCHEMISTRY

Serum paraoxonase-3 concentration in HIV-infected patients. Evidence for a protective role against oxidation

(2011) Gerard Aragonès et al.   JOURNAL OF LIPID RESEARCH

Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Biological activities of HDL subpopulations and their relevance to cardiovascular disease

(2011) Laurent Camont et al.   TRENDS IN MOLECULAR MEDICINE

A Role for the High-Density Lipoprotein Receptor SR-B1 in Synovial Inflammation via Serum Amyloid-A

(2010) Ronan Hugh Mullan et al.   AMERICAN JOURNAL OF PATHOLOGY

Selenium in Human Health and Disease

(2010) Susan J. Fairweather-Tait et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutathione Peroxidase-1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities

(2010) Edith Lubos et al.   ANTIOXIDANTS & REDOX SIGNALING

Pharmacological and dietary modulators of paraoxonase 1 (PON1) activity and expression: The hunt goes on

(2010) Lucio G. Costa et al.   BIOCHEMICAL PHARMACOLOGY

Alterations of plasma magnesium, copper, zinc, iron and selenium concentrations and some related erythrocyte antioxidant enzyme activities in patients with Alzheimer’s disease

(2010) Huseyin Vural et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Lipoprotein-associated phospholipase A2 and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies

(2010)   LANCET

Τhe role of lipoprotein-associated phospholipase A2 in atherosclerosis may depend on its lipoprotein carrier in plasma

(2009) Constantinos C. Tellis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Systemic Oxidative Stress Associated with the Neurological Diseases of Aging

(2009) Jorge A. Serra et al.   NEUROCHEMICAL RESEARCH

Changes of some oxidative stress markers in the serum of patients with mild cognitive impairment and Alzheimer's disease

(2009) Manuela Padurariu et al.   NEUROSCIENCE LETTERS

Immunohistochemical analysis of paraoxonases-1, 2, and 3 expression in normal mouse tissues

(2008) Judit Marsillach et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dominant Role of Paraoxonases in Inactivation of the Pseudomonas aeruginosa Quorum-Sensing Signal N-(3-Oxododecanoyl)-L-Homoserine Lactone

(2008) J. F. Teiber et al.   INFECTION AND IMMUNITY

Plasma membrane glutathione transporters and their roles in cell physiology and pathophysiology

(2008) Nazzareno Ballatori et al.   MOLECULAR ASPECTS OF MEDICINE

Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidase

(2008) M. O. Breckwoldt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA