PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

Diet-induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism

(2013) Junxian Lim et al.   FASEB JOURNAL

Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling

(2013) Lauren S. Csaki et al.   PROGRESS IN LIPID RESEARCH

Inflammation in Atherosclerosis

(2012) Peter Libby   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

PON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell death

(2012) E-M Schweikert et al.   CELL DEATH AND DIFFERENTIATION

ABCC6 Localizes to the Mitochondria-Associated Membrane

(2012) Lisa J. Martin et al.   CIRCULATION RESEARCH

Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum

(2012) J. R. Dwyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protease-Activated Receptor 1 and Hematopoietic Cell Tissue Factor Are Required for Hepatic Steatosis in Mice Fed a Western Diet

(2011) Karen M. Kassel et al.   AMERICAN JOURNAL OF PATHOLOGY

Disruption of paraoxonase 3 impairs proliferation and antioxidant defenses in human A549 cells and causes embryonic lethality in mice

(2011) Sarah L. Kempster et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Analysis of cholesteryl esters and diacylglycerols using lithiated adducts and electrospray ionization-tandem mass spectrometry

(2011) John A. Bowden et al.   ANALYTICAL BIOCHEMISTRY

Cholesterol induces pancreatic β cell apoptosis through oxidative stress pathway

(2011) Xiuli Lu et al.   CELL STRESS & CHAPERONES

Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice

(2011) Savitha Subramanian et al.   JOURNAL OF LIPID RESEARCH

High Throughput Microplate Respiratory Measurements Using Minimal Quantities Of Isolated Mitochondria

(2011) George W. Rogers et al.   PLoS One

Paraoxonase 2 Deficiency Alters Mitochondrial Function and Exacerbates the Development of Atherosclerosis

(2010) Asokan Devarajan et al.   ANTIOXIDANTS & REDOX SIGNALING

The three-gene paraoxonase family: Physiologic roles, actions and regulation

(2010) Louis-Philippe Précourt et al.   ATHEROSCLEROSIS

Embryonic Survival and Severity of Cardiac and Craniofacial Defects Are Affected by Genetic Background in Fibroblast Growth Factor-16 Null Mice

(2010) Shun Yan Lu et al.   DNA AND CELL BIOLOGY

An intimate liaison: spatial organization of the endoplasmic reticulum–mitochondria relationship

(2010) Olga Martins de Brito et al.   EMBO JOURNAL

One Enzyme, Two Functions

(2010) Sebastian Altenhöfer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spontaneous Irs1 passenger mutation linked to a gene-targeted SerpinB2 allele

(2010) R. J. Westrick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Common Mutation in Paraoxonase-2 Results in Impaired Lactonase Activity

(2009) David A. Stoltz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells

(2009) Mariusz R Wieckowski et al.   Nature Protocols

MAM: more than just a housekeeper

(2009) Teruo Hayashi et al.   TRENDS IN CELL BIOLOGY

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Genetic background conversion ameliorates semi-lethality and permits behavioral analyses in cystathionine β-synthase-deficient mice, an animal model for hyperhomocysteinemia

(2008) Noriyuki Akahoshi et al.   HUMAN MOLECULAR GENETICS

Dominant Role of Paraoxonases in Inactivation of the Pseudomonas aeruginosa Quorum-Sensing Signal N-(3-Oxododecanoyl)-L-Homoserine Lactone

(2008) J. F. Teiber et al.   INFECTION AND IMMUNITY

Relationship of Paraoxonase 1 (PON1) Gene Polymorphisms and Functional Activity With Systemic Oxidative Stress and Cardiovascular Risk

(2008) Tamali Bhattacharyya   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis

(2008) Peixiang Zhang et al.   JOURNAL OF LIPID RESEARCH

Targeting bile-acid signalling for metabolic diseases

(2008) Charles Thomas et al.   NATURE REVIEWS DRUG DISCOVERY