Blood-Derived Plasma Protein Biomarkers for Alzheimer’s Disease in Han Chinese

Prevalence of dementia in mainland China, Hong Kong and Taiwan: an updated systematic review and meta-analysis

(2018) Yu-Tzu Wu et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

A Decade of Blood Biomarkers for Alzheimer’s Disease Research: An Evolving Field, Improving Study Designs, and the Challenge of Replication

(2018) Liu Shi et al.   JOURNAL OF ALZHEIMERS DISEASE

IGF and IGFBP as an index for discrimination between vitamin D supplementation responders and nonresponders in overweight Saudi subjects

(2018) Nasser M. Al-Daghri et al.   MEDICINE

Serum Amyloid P Component Accelerates the Formation and Enhances the Stability of Amyloid Fibrils in a Physiologically Significant Under-Saturated Solution of Amyloid-β42

(2018) Matthew Mold et al.   JOURNAL OF ALZHEIMERS DISEASE

Candidate Blood Proteome Markers of Alzheimer's Disease Onset and Progression: A Systematic Review and Replication Study

(2018) Steven J. Kiddle et al.   JOURNAL OF ALZHEIMERS DISEASE

A Candidate Plasma Protein Classifier to Identify Alzheimer's Disease

(2018) Xuemei Zhao et al.   JOURNAL OF ALZHEIMERS DISEASE

Decreased Expression of Cathepsin D in Monocytes is Related to the Defective Degradation of Amyloid-β in Alzheimer's Disease

(2018) Li Tian et al.   JOURNAL OF ALZHEIMERS DISEASE

Circulating miRNAs as Potential Biomarkers in Alzheimer's Disease

(2018) Daniela Galimberti et al.   JOURNAL OF ALZHEIMERS DISEASE

Why do trials for Alzheimer’s disease drugs keep failing? A discontinued drug perspective for 2010-2015

(2017) Dev Mehta et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Phenotype analysis of male transgenic mice overexpressing mutant IGFBP-2 lacking the Cardin–Weintraub sequence motif: Reduced expression of synaptic markers and myelin basic protein in the brain and a lower degree of anxiety-like behaviour

(2017) N. Schindler et al.   GROWTH HORMONE & IGF RESEARCH

Peripheral versus Central Index of Metabolic Dysfunction and Associations with Clinical and Pathological Outcomes in Alzheimer’s Disease

(2017) Kelsey E. McLimans et al.   JOURNAL OF ALZHEIMERS DISEASE

Plasma protein profiling for potential biomarkers in the early diagnosis of Alzheimer’s disease

(2017) Yuki Kitamura et al.   NEUROLOGICAL RESEARCH

Transthyretin and BRICHOS: The Paradox of Amyloidogenic Proteins with Anti-Amyloidogenic Activity for Aβ in the Central Nervous System

(2017) Joel N. Buxbaum et al.   Frontiers in Neuroscience

Deaths from Alzheimer’s Disease — United States, 1999–2014

(2017) Christopher A. Taylor et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Emerging amyloid disease-modifying drugs for Alzheimer’s disease

(2016) Daniela Galimberti et al.   EXPERT OPINION ON EMERGING DRUGS

Low Serum Insulin-Like Growth Factor-I Predicts Cognitive Decline in Alzheimer’s Disease

(2016) Jean-Sébastien Vidal et al.   JOURNAL OF ALZHEIMERS DISEASE

Biomarkers for the Early Detection and Progression of Alzheimer’s Disease

(2016) Scott E. Counts et al.   Neurotherapeutics

The RGD sequence present in IGFBP-2 is required for reduced glucose clearance after oral glucose administration in female transgenic mice

(2015) Anja Reyer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Prevention of sporadic Alzheimer's disease: lessons learned from clinical trials and future directions

(2015) Sandrine Andrieu et al.   LANCET NEUROLOGY

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Amyloid biomarkers in Alzheimer's disease

(2015) Kaj Blennow et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Current aging research in China

(2015) Ruijuan Sun et al.   Protein & Cell

Association of Insulin Resistance With Cerebral Glucose Uptake in Late Middle–Aged Adults at Risk for Alzheimer Disease

(2015) Auriel A. Willette et al.   JAMA Neurology

Plasma proteins predict conversion to dementia from prodromal disease

(2014) Abdul Hye et al.   Alzheimers & Dementia

Obesity and dementia: Adipokines interact with the brain

(2014) Ilse A.C. Arnoldussen et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Twelve Serum Proteins Progressively Increase With Disease Stage in Squamous Cell Cervical Cancer Patients

(2014) Wenbo Zhi et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

INFLAMMATION AND MENTAL ILLNESS

(2013) N. Harrison   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Characterization of Novel CSF Tau and ptau Biomarkers for Alzheimer’s Disease

(2013) Jere E. Meredith Jr. et al.   PLoS One

Serum but not cerebrospinal fluid levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 (IGFBP-3) are increased in Alzheimer's disease

(2013) Per Johansson et al.   PSYCHONEUROENDOCRINOLOGY

Development of biomarkers to chart all Alzheimer’s disease stages: The royal road to cutting the therapeutic Gordian Knot

(2012) Harald Hampel et al.   Alzheimers & Dementia

Plasma Amyloid-β as a Predictor of Dementia and Cognitive Decline

(2012) Alain Koyama et al.   ARCHIVES OF NEUROLOGY

Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease

(2012) James D. Doecke   ARCHIVES OF NEUROLOGY

Cerebrospinal fluid levels of complement proteins C3, C4 and CR1 in Alzheimer’s disease

(2012) Jonny Daborg et al.   JOURNAL OF NEURAL TRANSMISSION

Brain Amyloid Imaging — FDA Approval of Florbetapir F18 Injection

(2012) Lucie Yang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evaluation of a Previously Suggested Plasma Biomarker Panel to Identify Alzheimer's Disease

(2012) Maria Björkqvist et al.   PLoS One

Plasma Levels of Complement 4a Protein are Increased in Alzheimerʼs Disease

(2011) Stuart Bennett et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Biomarkers in Alzheimer's disease drug development

(2011) Jeffrey L. Cummings   Alzheimers & Dementia

A Blood-Based Algorithm for the Detection of Alzheimer’s Disease

(2011) Sid E. O’Bryant et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Identification of a blood-based biomarker panel for classification of Alzheimer's disease

(2011) Christoph Laske et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

Association of Plasma Clusterin Concentration With Severity, Pathology, and Progression in Alzheimer Disease

(2010) Madhav Thambisetty et al.   ARCHIVES OF GENERAL PSYCHIATRY

A Serum Protein–Based Algorithm for the Detection of Alzheimer Disease

(2010) Sid E. O’Bryant   ARCHIVES OF NEUROLOGY

Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

(2010) Sudha Seshadri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Identifying Early Markers of Alzheimer's Disease using Quantitative Multiplex Proteomic Immunoassay Panels

(2009) Holly D. Soares et al.   Annals of the New York Academy of Sciences

Insulin like growth factor-1 and insulin like growth factor binding proteins in the cerebrospinal fluid and serum from patients with Alzheimer's disease

(2009) Zivar Salehi et al.   BIOFACTORS

Circulating immune complexes of Aβ and IgM in plasma of patients with Alzheimer’s disease

(2009) Andrea Marcello et al.   JOURNAL OF NEURAL TRANSMISSION

Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer’s disease

(2009) Madhav Thambisetty et al.   JOURNAL OF NEUROLOGY

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Therapeutic potential of complement modulation

(2009) Eric Wagner et al.   NATURE REVIEWS DRUG DISCOVERY

Five out of 16 plasma signaling proteins are enhanced in plasma of patients with mild cognitive impairment and Alzheimer's disease

(2009) Josef Marksteiner et al.   NEUROBIOLOGY OF AGING

Hypertension and Cerebrovascular Dysfunction

(2008) Costantino Iadecola et al.   Cell Metabolism

Potential roles of abundant extracellular chaperones in the control of amyloid formation and toxicity

(2007) Mark R. Wilson et al.   Molecular BioSystems