- Home
- Publications
- Publication Search
- Publication Details
Title
Factors that mold the nuclear landscape of HIV-1 integration
Authors
Keywords
-
Journal
NUCLEIC ACIDS RESEARCH
Volume 49, Issue 2, Pages 621-635
Publisher
Oxford University Press (OUP)
Online
2020-11-27
DOI
10.1093/nar/gkaa1207
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Arginine-Enriched Mixed-Charge Domains Provide Cohesion for Nuclear Speckle Condensation
- (2020) Jamie A. Greig et al. MOLECULAR CELL
- HIV-1 uncoats in the nucleus near sites of integration
- (2020) Ryan C. Burdick et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes
- (2020) Guillermo Blanco-Rodriguez et al. JOURNAL OF VIROLOGY
- Nucleoporin 153 links nuclear pore complex to chromatin architecture by mediating CTCF and cohesin binding
- (2020) Shinichi Kadota et al. Nature Communications
- Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core
- (2020) Anastasia Selyutina et al. Cell Reports
- Nuclear pore blockade reveals that HIV-1 completes reverse transcription and uncoating in the nucleus
- (2020) Adarsh Dharan et al. Nature Microbiology
- Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A
- (2020) Tao Ni et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The chromatin landscape at the HIV-1 provirus integration site determines viral expression
- (2020) Gerlinde Vansant et al. NUCLEIC ACIDS RESEARCH
- HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains
- (2020) Ashwanth C. Francis et al. Nature Communications
- Distinct viral reservoirs in individuals with spontaneous control of HIV-1
- (2020) Chenyang Jiang et al. NATURE
- CPSF6-Dependent Targeting of Speckle-Associated Domains Distinguishes Primate from Nonprimate Lentiviral Integration
- (2020) Wen Li et al. mBio
- Nuclear Import of the HIV-1 Core Precedes Reverse Transcription and Uncoating
- (2020) Anastasia Selyutina et al. Cell Reports
- HIV-1 nuclear import in macrophages is regulated by CPSF6-capsid interactions at the Nuclear Pore Complex
- (2019) David Alejandro Bejarano et al. eLife
- Differential role for phosphorylation in alternative polyadenylation function versus nuclear import of SR-like protein CPSF6
- (2019) Sooin Jang et al. NUCLEIC ACIDS RESEARCH
- Human H4 tail stimulates HIV-1 integration through binding to the carboxy-terminal domain of integrase
- (2019) Eric Mauro et al. NUCLEIC ACIDS RESEARCH
- The Structure of the Nuclear Pore Complex (An Update)
- (2019) Daniel H. Lin et al. Annual Review of Biochemistry
- Genome organization around nuclear speckles
- (2019) Yu Chen et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Chromatin targeting of nuclear pore proteins induces chromatin decondensation
- (2019) Terra M. Kuhn et al. JOURNAL OF CELL BIOLOGY
- Molecular Mechanism of HIV-1 Entry
- (2019) Bing Chen TRENDS IN MICROBIOLOGY
- Multifaceted HIV integrase functionalities and therapeutic strategies for their inhibition
- (2019) Alan N. Engelman JOURNAL OF BIOLOGICAL CHEMISTRY
- Analysis of CA Content and CPSF6 Dependence of Early HIV-1 Replication Complexes in SupT1-R5 Cells
- (2019) Vojtech Zila et al. mBio
- Spatially clustered loci with multiple enhancers are frequent targets of HIV-1 integration
- (2019) Bojana Lucic et al. Nature Communications
- Transportin-1 binds to the HIV-1 capsid via a nuclear localization signal and triggers uncoating
- (2019) Juliette Fernandez et al. Nature Microbiology
- LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells
- (2019) Gary LeRoy et al. Science Advances
- The Critical Role of Bach2 in Shaping the Balance between CD4+ T Cell Subsets in Immune-Mediated Diseases
- (2019) Lingyi Yang et al. MEDIATORS OF INFLAMMATION
- Structure of H3K36-methylated nucleosome–PWWP complex reveals multivalent cross-gyre binding
- (2019) Haibo Wang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Single HIV-1 Imaging Reveals Progression of Infection through CA-Dependent Steps of Docking at the Nuclear Pore, Uncoating, and Nuclear Transport
- (2018) Ashwanth C. Francis et al. Cell Host & Microbe
- Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Non-dividing Cells
- (2018) Cindy Buffone et al. JOURNAL OF VIROLOGY
- Inhibitors of the integrase–transportin-SR2 interaction block HIV nuclear import
- (2018) Jonas Demeulemeester et al. Retrovirology
- Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration
- (2018) Vasudevan Achuthan et al. Cell Host & Microbe
- Molecular dissection of an inhibitor targeting the HIV integrase dependent preintegration complex nuclear import
- (2018) Kylie M. Wagstaff et al. CELLULAR MICROBIOLOGY
- Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler
- (2018) Yu Chen et al. JOURNAL OF CELL BIOLOGY
- Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2
- (2018) Melissa Kane et al. eLife
- Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4 + T Cells Permissive for Latent HIV-1 Infection
- (2017) Liang Shan et al. IMMUNITY
- Proliferation of latently infected CD4+T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics
- (2017) Nina N. Hosmane et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Imaging HIV-1 Genomic DNA from Entry through Productive Infection
- (2017) Ryan D. Stultz et al. JOURNAL OF VIROLOGY
- Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails
- (2017) Mohamed S. Benleulmi et al. Retrovirology
- Capsid-Dependent Host Factors in HIV-1 Infection
- (2017) Masahiro Yamashita et al. TRENDS IN MICROBIOLOGY
- HIV-1-mediated insertional activation of STAT5B and BACH2 trigger viral reservoir in T regulatory cells
- (2017) Daniela Cesana et al. Nature Communications
- Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir
- (2017) John K. Bui et al. PLoS Pathogens
- The Nuclear Pore Complex as a Flexible and Dynamic Gate
- (2016) Kevin E. Knockenhauer et al. CELL
- What Integration Sites Tell Us about HIV Persistence
- (2016) Stephen H. Hughes et al. Cell Host & Microbe
- The mTOR Complex Controls HIV Latency
- (2016) Emilie Besnard et al. Cell Host & Microbe
- Retroviral DNA Integration
- (2016) Paul Lesbats et al. CHEMICAL REVIEWS
- Nucleoporins and chromatin metabolism
- (2016) Christopher Ptak et al. CURRENT OPINION IN CELL BIOLOGY
- The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes
- (2016) Sheeba Rasheedi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Simple rules for passive diffusion through the nuclear pore complex
- (2016) Benjamin L. Timney et al. JOURNAL OF CELL BIOLOGY
- The role of HIV integration in viral persistence: no more whistling past the proviral graveyard
- (2016) Frank Maldarelli JOURNAL OF CLINICAL INVESTIGATION
- STAT5 in Cancer and Immunity
- (2016) Aradhana Rani et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus PassageIn Vivo
- (2016) Akatsuki Saito et al. JOURNAL OF VIROLOGY
- Defective proviruses rapidly accumulate during acute HIV-1 infection
- (2016) Katherine M Bruner et al. NATURE MEDICINE
- Alternative polyadenylation of mRNA precursors
- (2016) Bin Tian et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Position effects influence HIV latency reversal
- (2016) Heng-Chang Chen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- DNA minicircles clarify the specific role of DNA structure on retroviral integration
- (2016) Marco Pasi et al. NUCLEIC ACIDS RESEARCH
- A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin
- (2016) Gregory A. Sowd et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA
- (2016) Julio C. C. Lorenzi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clonally expanded CD4+T cells can produce infectious HIV-1 in vivo
- (2016) Francesco R. Simonetti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The structure and flexibility of conical HIV-1 capsids determined within intact virions
- (2016) Simone Mattei et al. SCIENCE
- Position effects influence HIV latency reversal
- (2016) Heng-Chang Chen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The Many Roles of BAF (mSWI/SNF) and PBAF Complexes in Cancer
- (2016) Courtney Hodges et al. Cold Spring Harbor Perspectives in Medicine
- KIF5B and Nup358 Cooperatively Mediate the Nuclear Import of HIV-1 during Infection
- (2016) Adarsh Dharan et al. PLoS Pathogens
- HIV-1 Integration Landscape during Latent and Active Infection
- (2015) Lillian B. Cohn et al. CELL
- LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes
- (2015) Parmit Kumar Singh et al. GENES & DEVELOPMENT
- Nuclear architecture dictates HIV-1 integration site selection
- (2015) Bruna Marini et al. NATURE
- HIV-1 capsid: the multifaceted key player in HIV-1 infection
- (2015) Edward M. Campbell et al. NATURE REVIEWS MICROBIOLOGY
- Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif
- (2015) Petr Tesina et al. Nature Communications
- Chromatin organization at the nuclear pore favours HIV replication
- (2015) Mickaël Lelek et al. Nature Communications
- Direct Visualization of HIV-1 Replication Intermediates Shows that Capsid and CPSF6 Modulate HIV-1 Intra-nuclear Invasion and Integration
- (2015) Christopher R. Chin et al. Cell Reports
- HIV Latency Is Established Directly and Early in Both Resting and Activated Primary CD4 T Cells
- (2015) Leonard Chavez et al. PLoS Pathogens
- HIV-1 Integrase Variants Retarget Viral Integration and Are Associated with Disease Progression in a Chronic Infection Cohort
- (2014) Jonas Demeulemeester et al. Cell Host & Microbe
- The HIV-1 Integrase Mutant R263A/K264A Is 2-fold Defective for TRN-SR2 Binding and Viral Nuclear Import
- (2014) Stéphanie De Houwer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Impairment of HIV-1 cDNA Synthesis by DBR1 Knockdown
- (2014) A. E. Galvis et al. JOURNAL OF VIROLOGY
- Integrase residues that determine nucleotide preferences at sites of HIV-1 integration: implications for the mechanism of target DNA binding
- (2014) Erik Serrao et al. NUCLEIC ACIDS RESEARCH
- The landscape and therapeutic relevance of cancer-associated transcript fusions
- (2014) K Yoshihara et al. ONCOGENE
- Structural basis for nuclear import of splicing factors by human Transportin 3
- (2014) G. N. Maertens et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis of HIV-1 capsid recognition by PF74 and CPSF6
- (2014) Akash Bhattacharya et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cyclophilin A promotes HIV-1 reverse transcription but its effect on transduction correlates best with its effect on nuclear entry of viral cDNA
- (2014) Alberto De Iaco et al. Retrovirology
- BI-2 destabilizes HIV-1 cores during infection and Prevents Binding of CPSF6 to the HIV-1 Capsid
- (2014) Thomas Fricke et al. Retrovirology
- Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection
- (2014) T. A. Wagner et al. SCIENCE
- Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
- (2014) F. Maldarelli et al. SCIENCE
- Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly
- (2014) Amanda J. Price et al. PLoS Pathogens
- A Cyclophilin Homology Domain-Independent Role for Nup358 in HIV-1 Infection
- (2014) Anne M. Meehan et al. PLoS Pathogens
- Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid
- (2014) Ke Peng et al. eLife
- Transportin 3 and importin α are required for effective nuclear import of HIV-1 integrase in virus-infected cells
- (2014) Aviad Levin et al. Nucleus
- Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure
- (2013) Ya-Chi Ho et al. CELL
- Structural and Functional Analysis of the C-Terminal Domain of Nup358/RanBP2
- (2013) Daniel H. Lin et al. JOURNAL OF MOLECULAR BIOLOGY
- Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics
- (2013) Gongpu Zhao et al. NATURE
- Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes
- (2013) Jocelyn O. Eidahl et al. NUCLEIC ACIDS RESEARCH
- Single-Cell Imaging of HIV-1 Provirus (SCIP)
- (2013) C. Di Primio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The ability of TNPO3-depleted cells to inhibit HIV-1 infection requires CPSF6
- (2013) Thomas Fricke et al. Retrovirology
- TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm
- (2013) Alberto De Iaco et al. Retrovirology
- Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication
- (2013) Francesca Di Nunzio et al. VIROLOGY
- Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain
- (2013) Rick van Nuland et al. Epigenetics & Chromatin
- HIV Pathogenesis: Dynamics and Genetics of Viral Populations and Infected Cells
- (2013) J. Coffin et al. Cold Spring Harbor Perspectives in Medicine
- Nucleoporin NUP153 Phenylalanine-Glycine Motifs Engage a Common Binding Pocket within the HIV-1 Capsid Protein to Mediate Lentiviral Infectivity
- (2013) Kenneth A. Matreyek et al. PLoS Pathogens
- Redefining the Viral Reservoirs that Prevent HIV-1 Eradication
- (2012) Evelyn Eisele et al. IMMUNITY
- Contribution of Host Nucleoporin 62 in HIV-1 Integrase Chromatin Association and Viral DNA Integration
- (2012) Zhujun Ao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HIV-1 Capsid-Targeting Domain of Cleavage and Polyadenylation Specificity Factor 6
- (2012) K. Lee et al. JOURNAL OF VIROLOGY
- Differential Effects of Human Immunodeficiency Virus Type 1 Capsid and Cellular Factors Nucleoporin 153 and LEDGF/p75 on the Efficiency and Specificity of Viral DNA Integration
- (2012) Y. Koh et al. JOURNAL OF VIROLOGY
- HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor
- (2012) Hao Wang et al. NUCLEIC ACIDS RESEARCH
- Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration
- (2012) Francesca Di Nunzio et al. PLoS One
- HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells
- (2012) Rik Schrijvers et al. Retrovirology
- Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing
- (2012) Madapura M. Pradeepa et al. PLoS Genetics
- LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs
- (2012) Rik Schrijvers et al. PLoS Pathogens
- Directly Infected Resting CD4+T Cells Can Produce HIV Gag without Spreading Infection in a Model of HIV Latency
- (2012) Matthew J. Pace et al. PLoS Pathogens
- CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication
- (2012) Amanda J. Price et al. PLoS Pathogens
- Influence of Host Gene Transcription Level and Orientation on HIV-1 Latency in a Primary-Cell Model
- (2011) L. Shan et al. JOURNAL OF VIROLOGY
- Epigenetic Silencing of HIV-1 by the Histone H3 Lysine 27 Methyltransferase Enhancer of Zeste 2
- (2011) J. Friedman et al. JOURNAL OF VIROLOGY
- Atomic-level modelling of the HIV capsid
- (2011) Owen Pornillos et al. NATURE
- The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1
- (2011) S Muehlich et al. ONCOGENE
- Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection
- (2011) Candela Iglesias et al. Retrovirology
- Mutations affecting interaction of integrase with TNPO3 do not prevent HIV-1 cDNA nuclear import
- (2011) Alexandra Cribier et al. Retrovirology
- Crystal Structure of a Human Cleavage Factor CFIm25/CFIm68/RNA Complex Provides an Insight into Poly(A) Site Recognition and RNA Looping
- (2011) Qin Yang et al. STRUCTURE
- HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency
- (2011) Torsten Schaller et al. PLoS Pathogens
- HIV Integration Targeting: A Pathway Involving Transportin-3 and the Nuclear Pore Protein RanBP2
- (2011) Karen E. Ocwieja et al. PLoS Pathogens
- Transportin 3 Promotes a Nuclear Maturation Step Required for Efficient HIV-1 Integration
- (2011) Lihong Zhou et al. PLoS Pathogens
- The importin β binding domain as a master regulator of nucleocytoplasmic transport
- (2010) Kaylen Lott et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Flexible Use of Nuclear Import Pathways by HIV-1
- (2010) KyeongEun Lee et al. Cell Host & Microbe
- Involvement of Histone H3 Lysine 9 (H3K9) Methyltransferase G9a in the Maintenance of HIV-1 Latency and Its Reactivation by BIX01294
- (2010) Kenichi Imai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Importin 3 Interacts with HIV-1 Integrase and Contributes to HIV-1 Nuclear Import and Replication
- (2010) Z. Ao et al. JOURNAL OF VIROLOGY
- The mechanism of retroviral integration from X-ray structures of its key intermediates
- (2010) Goedele N. Maertens et al. NATURE
- HIV integration site distributions in resting and activated CD4+ T cells infected in culture
- (2009) Troy Brady et al. AIDS
- Structural Convergence between Cryo-EM and NMR Reveals Intersubunit Interactions Critical for HIV-1 Capsid Function
- (2009) In-Ja L. Byeon et al. CELL
- X-Ray Structures of the Hexameric Building Block of the HIV Capsid
- (2009) Owen Pornillos et al. CELL
- Human Immunodeficiency Virus Integrates Directly into Naive Resting CD4+ T Cells but Enters Naive Cells Less Efficiently than Memory Cells
- (2009) J. Dai et al. JOURNAL OF VIROLOGY
- Analysis of the Viral Elements Required in the Nuclear Import of HIV-1 DNA
- (2009) L. Riviere et al. JOURNAL OF VIROLOGY
- The Requirement for Cellular Transportin 3 (TNPO3 or TRN-SR2) during Infection Maps to Human Immunodeficiency Virus Type 1 Capsid and Not Integrase
- (2009) L. Krishnan et al. JOURNAL OF VIROLOGY
- Integrase Interacts with Nucleoporin NUP153 To Mediate the Nuclear Import of Human Immunodeficiency Virus Type 1
- (2009) C. L. Woodward et al. JOURNAL OF VIROLOGY
- A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75
- (2009) Stephen Hare et al. PLoS Pathogens
- CpG Methylation Controls Reactivation of HIV from Latency
- (2009) Jana Blazkova et al. PLoS Pathogens
- Epigenetic Regulation of HIV-1 Latency by Cytosine Methylation
- (2009) Steven E. Kauder et al. PLoS Pathogens
- Menin Critically Links MLL Proteins with LEDGF on Cancer-Associated Target Genes
- (2008) Akihiko Yokoyama et al. CANCER CELL
- Orientation-Dependent Regulation of Integrated HIV-1 Expression by Host Gene Transcriptional Readthrough
- (2008) Yefei Han et al. Cell Host & Microbe
- Transcriptional Interference Antagonizes Proviral Gene Expression to Promote HIV Latency
- (2008) Tina Lenasi et al. Cell Host & Microbe
- Transportin-SR2 Imports HIV into the Nucleus
- (2008) Frauke Christ et al. CURRENT BIOLOGY
- Identification and Characterization of PWWP Domain Residues Critical for LEDGF/p75 Chromatin Binding and Human Immunodeficiency Virus Type 1 Infectivity
- (2008) M.-C. Shun et al. JOURNAL OF VIROLOGY
- HIV-1 Pre-Integration Complexes Selectively Target Decondensed Chromatin in the Nuclear Periphery
- (2008) Alberto Albanese et al. PLoS One
- Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen
- (2008) Abraham L. Brass et al. SCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search