Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes

Capsid labelled HIV to investigate the role of capsid during nuclear import and integration

(2020) Irena Zurnic Bönisch et al.   JOURNAL OF VIROLOGY

The forces driving clonal expansion of the HIV-1 latent reservoir

(2020) Runxia Liu et al.   Virology Journal

HIV-1 nuclear import in macrophages is regulated by CPSF6-capsid interactions at the Nuclear Pore Complex

(2019) David Alejandro Bejarano et al.   eLife

A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model

(2019) Stephen R. Yant et al.   NATURE MEDICINE

Single HIV-1 Imaging Reveals Progression of Infection through CA-Dependent Steps of Docking at the Nuclear Pore, Uncoating, and Nuclear Transport

(2018) Ashwanth C. Francis et al.   Cell Host & Microbe

Real-time visualization and quantification of human Cytomegalovirus replication in living cells using the ANCHOR DNA labeling technology.

(2018) Bernard Mariamé et al.   JOURNAL OF VIROLOGY

In vivo labelling of adenovirus DNA identifies chromatin anchoring and biphasic genome replication.

(2018) Tetsuro Komatsu et al.   JOURNAL OF VIROLOGY

Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Non-dividing Cells

(2018) Cindy Buffone et al.   JOURNAL OF VIROLOGY

Live-Cell Imaging of Early Steps of Single HIV-1 Infection

(2018) Ashwanth Francis et al.   Viruses-Basel

Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis

(2018) Chantal L Márquez et al.   eLife

Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration

(2018) Vasudevan Achuthan et al.   Cell Host & Microbe

Imaging HIV-1 Genomic DNA from Entry through Productive Infection

(2017) Ryan D. Stultz et al.   JOURNAL OF VIROLOGY

eC-CLEM: flexible multidimensional registration software for correlative microscopies

(2017) Perrine Paul-Gilloteaux et al.   NATURE METHODS

Early cytoplasmic uncoating is associated with infectivity of HIV-1

(2017) João I. Mamede et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiplex single-cell visualization of nucleic acids and protein during HIV infection

(2017) Maritza Puray-Chavez et al.   Nature Communications

Dynamics and regulation of nuclear import and nuclear movements of HIV-1 complexes

(2017) Ryan C. Burdick et al.   PLoS Pathogens

Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74

(2016) Akatsuki Saito et al.   JOURNAL OF VIROLOGY

HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis

(2016) David A. Jacques et al.   NATURE

A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin

(2016) Gregory A. Sowd et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 capsid is involved in post-nuclear entry steps

(2016) Nan-Yu Chen et al.   Retrovirology

The structure and flexibility of conical HIV-1 capsids determined within intact virions

(2016) Simone Mattei et al.   SCIENCE

Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells

(2016) Ashwanth C. Francis et al.   PLoS Pathogens

Nuclear architecture dictates HIV-1 integration site selection

(2015) Bruna Marini et al.   NATURE

HIV-1 capsid: the multifaceted key player in HIV-1 infection

(2015) Edward M. Campbell et al.   NATURE REVIEWS MICROBIOLOGY

Chromatin organization at the nuclear pore favours HIV replication

(2015) Mickaël Lelek et al.   Nature Communications

Direct Visualization of HIV-1 Replication Intermediates Shows that Capsid and CPSF6 Modulate HIV-1 Intra-nuclear Invasion and Integration

(2015) Christopher R. Chin et al.   Cell Reports

Stochastic Self-Assembly of ParB Proteins Builds the Bacterial DNA Segregation Apparatus

(2015) Aurore Sanchez et al.   Cell Systems

ParB spreading requires DNA bridging

(2014) T. G. W. Graham et al.   GENES & DEVELOPMENT

Vitrification of Tokuyasu-style immuno-labelled sections for correlative cryo light microscopy and cryo electron tomography

(2014) Erik Bos et al.   JOURNAL OF STRUCTURAL BIOLOGY

Specific HIV integration sites are linked to clonal expansion and persistence of infected cells

(2014) F. Maldarelli et al.   SCIENCE

DNA Dynamics during Early Double-Strand Break Processing Revealed by Non-Intrusive Imaging of Living Cells

(2014) Hicham Saad et al.   PLoS Genetics

Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly

(2014) Amanda J. Price et al.   PLoS Pathogens

Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid

(2014) Ke Peng et al.   eLife

Multi-resolution correlative focused ion beam scanning electron microscopy: Applications to cell biology

(2013) Kedar Narayan et al.   JOURNAL OF STRUCTURAL BIOLOGY

HIV-1 evades innate immune recognition through specific cofactor recruitment

(2013) Jane Rasaiyaah et al.   NATURE

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

(2013) Caroline Goujon et al.   NATURE

Peptide nanofibrils boost retroviral gene transfer and provide a rapid means for concentrating viruses

(2013) Maral Yolamanova et al.   Nature Nanotechnology

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication

(2013) Francesca Di Nunzio et al.   VIROLOGY

Extreme Genetic Fragility of the HIV-1 Capsid

(2013) Suzannah J. Rihn et al.   PLoS Pathogens

Nucleoporin NUP153 Phenylalanine-Glycine Motifs Engage a Common Binding Pocket within the HIV-1 Capsid Protein to Mediate Lentiviral Infectivity

(2013) Kenneth A. Matreyek et al.   PLoS Pathogens

TNPO3 Is Required for HIV-1 Replication after Nuclear Import but prior to Integration and Binds the HIV-1 Core

(2012) J. C. Valle-Casuso et al.   JOURNAL OF VIROLOGY

Icy: an open bioimage informatics platform for extended reproducible research

(2012) Fabrice de Chaumont et al.   NATURE METHODS

Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration

(2012) Francesca Di Nunzio et al.   PLoS One

CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication

(2012) Amanda J. Price et al.   PLoS Pathogens

Atomic-level modelling of the HIV capsid

(2011) Owen Pornillos et al.   NATURE

Complementary assays reveal a relationship between HIV-1 uncoating and reverse transcription

(2011) A. E. Hulme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

(2011) Torsten Schaller et al.   PLoS Pathogens

Transportin 3 Promotes a Nuclear Maturation Step Required for Efficient HIV-1 Integration

(2011) Lihong Zhou et al.   PLoS Pathogens

Flexible Use of Nuclear Import Pathways by HIV-1

(2010) KyeongEun Lee et al.   Cell Host & Microbe

Gyrase B Inhibitor Impairs HIV-1 Replication by Targeting Hsp90 and the Capsid Protein

(2010) Luciano Vozzolo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1

(2010) Nan Yan et al.   NATURE IMMUNOLOGY