The HIV-1 Integrase Mutant R263A/K264A Is 2-fold Defective for TRN-SR2 Binding and Viral Nuclear Import

Structural basis for nuclear import of splicing factors by human Transportin 3

(2014) G. N. Maertens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of transportin SR2, a karyopherin involved in human disease, in complex with Ran

(2014) Vicky G. Tsirkone et al.   Acta Crystallographica Section F-Structural Biology Communications

Interaction of Transportin-SR2 with Ras-related Nuclear Protein (Ran) GTPase

(2013) Oliver Taltynov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ability of TNPO3-depleted cells to inhibit HIV-1 infection requires CPSF6

(2013) Thomas Fricke et al.   Retrovirology

TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm

(2013) Alberto De Iaco et al.   Retrovirology

Interaction of the HIV-1 Intasome with Transportin 3 Protein (TNPO3 or TRN-SR2)

(2012) Ross Larue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Residues in the C-terminal Domain of HIV-1 Integrase That Mediate Binding to the Transportin-SR2 Protein

(2012) Stephanie De Houwer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Correlation of Recombinant Integrase Activity and Functional Preintegration Complex Formation during Acute Infection by Replication-Defective Integrase Mutant Human Immunodeficiency Virus

(2012) X. Li et al.   JOURNAL OF VIROLOGY

Human Immunodeficiency Virus Type 1 Capsid Mutation N74D Alters Cyclophilin A Dependence and Impairs Macrophage Infection

(2012) Zandrea Ambrose et al.   JOURNAL OF VIROLOGY

TNPO3 Is Required for HIV-1 Replication after Nuclear Import but prior to Integration and Binds the HIV-1 Core

(2012) J. C. Valle-Casuso et al.   JOURNAL OF VIROLOGY

The Host Proteins Transportin SR2/TNPO3 and Cyclophilin A Exert Opposing Effects on HIV-1 Uncoating

(2012) V. B. Shah et al.   JOURNAL OF VIROLOGY

CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication

(2012) Amanda J. Price et al.   PLoS Pathogens

Identification of Critical Motifs within HIV-1 Integrase Required for Importin α3 Interaction and Viral cDNA Nuclear Import

(2011) Kallesh Danappa Jayappa et al.   JOURNAL OF MOLECULAR BIOLOGY

The Cargo-Binding Domain of Transportin 3 Is Required for Lentivirus Nuclear Import

(2011) E. C. Logue et al.   JOURNAL OF VIROLOGY

Sequential Deletion of the Integrase (Gag-Pol) Carboxyl Terminus Reveals Distinct Phenotypic Classes of Defective HIV-1

(2011) K. D. Mohammed et al.   JOURNAL OF VIROLOGY

Interplay between HIV Entry and Transportin-SR2 Dependency

(2011) Wannes Thys et al.   Retrovirology

Inhibition of HIV-1 infection by TNPO3 depletion is determined by capsid and detectable after viral cDNA enters the nucleus

(2011) Alberto De Iaco et al.   Retrovirology

Mutations affecting interaction of integrase with TNPO3 do not prevent HIV-1 cDNA nuclear import

(2011) Alexandra Cribier et al.   Retrovirology

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

(2011) Torsten Schaller et al.   PLoS Pathogens

HIV Integration Targeting: A Pathway Involving Transportin-3 and the Nuclear Pore Protein RanBP2

(2011) Karen E. Ocwieja et al.   PLoS Pathogens

Transportin 3 Promotes a Nuclear Maturation Step Required for Efficient HIV-1 Integration

(2011) Lihong Zhou et al.   PLoS Pathogens

Flexible Use of Nuclear Import Pathways by HIV-1

(2010) KyeongEun Lee et al.   Cell Host & Microbe

Importin  3 Interacts with HIV-1 Integrase and Contributes to HIV-1 Nuclear Import and Replication

(2010) Z. Ao et al.   JOURNAL OF VIROLOGY

Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication

(2010) Frauke Christ et al.   Nature Chemical Biology

The Requirement for Cellular Transportin 3 (TNPO3 or TRN-SR2) during Infection Maps to Human Immunodeficiency Virus Type 1 Capsid and Not Integrase

(2009) L. Krishnan et al.   JOURNAL OF VIROLOGY

HIV-1 exploits importin 7 to maximize nuclear import of its DNA genome

(2009) Lyubov Zaitseva et al.   Retrovirology

Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication

(2008) Renate König et al.   CELL

Transportin-SR2 Imports HIV into the Nucleus

(2008) Frauke Christ et al.   CURRENT BIOLOGY

HIV-1 Pre-Integration Complexes Selectively Target Decondensed Chromatin in the Nuclear Periphery

(2008) Alberto Albanese et al.   PLoS One

Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

(2008) Abraham L. Brass et al.   SCIENCE