Recent advances in neurotechnologies with broad potential for neuroscience research

A sensitive and specific nanosensor for monitoring extracellular potassium levels in the brain

(2020) Jianan Liu et al.   Nature Nanotechnology

Engineering genetically encoded fluorescent indicators for imaging of neuronal activity: Progress and prospects

(2020) Yi Shen et al.   NEUROSCIENCE RESEARCH

Wireless, battery-free subdermally implantable photometry systems for chronic recording of neural dynamics

(2020) Alex Burton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconfigurable nanophotonic silicon probes for sub-millisecond deep-brain optical stimulation

(2020) Aseema Mohanty et al.   Nature Biomedical Engineering

Expanding the Chemogenetic Toolbox by Circular Permutation

(2020) Yi-Tsang Lee et al.   JOURNAL OF MOLECULAR BIOLOGY

Materials for flexible bioelectronic systems as chronic neural interfaces

(2020) Enming Song et al.   NATURE MATERIALS

An Ultra-Sensitive Step-Function Opsin for Minimally Invasive Optogenetic Stimulation in Mice and Macaques

(2020) Xin Gong et al.   NEURON

Development of a neural interface for high-definition, long-term recording in rodents and nonhuman primates

(2020) Chia-Han Chiang et al.   Science Translational Medicine

Translational Neuroelectronics

(2020) Patricia Jastrzebska‐Perfect et al.   ADVANCED FUNCTIONAL MATERIALS

Fluorescent sensors for neuronal signaling

(2020) Colin P O’Banion et al.   CURRENT OPINION IN NEUROBIOLOGY

A wireless, implantable optoelectrochemical probe for optogenetic stimulation and dopamine detection

(2020) Changbo Liu et al.   Microsystems & Nanoengineering

A genetically encoded near-infrared fluorescent calcium ion indicator

(2019) Yong Qian et al.   NATURE METHODS

Soft and elastic hydrogel-based microelectronics for localized low-voltage neuromodulation

(2019) Yuxin Liu et al.   Nature Biomedical Engineering

Wireless, battery-free optoelectronic systems as subdermal implants for local tissue oximetry

(2019) Hao Zhang et al.   Science Advances

A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP

(2019) Mark A. Lobas et al.   Nature Communications

A Genetically Encoded Fluorescent Sensor for Rapid and Specific In Vivo Detection of Norepinephrine

(2019) Jiesi Feng et al.   NEURON

Novel electrode technologies for neural recordings

(2019) Guosong Hong et al.   NATURE REVIEWS NEUROSCIENCE

Bioinspired neuron-like electronics

(2019) Xiao Yang et al.   NATURE MATERIALS

Biomarkers for closed-loop deep brain stimulation in Parkinson disease and beyond

(2019) Walid Bouthour et al.   Nature Reviews Neurology

Latest Trends in Electrochemical Sensors for Neurotransmitters: A Review

(2019) Tavakolian-Ardakani et al.   SENSORS

Optimal Electrode Size for Multi-Scale Extracellular-Potential Recording From Neuronal Assemblies

(2019) Vijay Viswam et al.   Frontiers in Neuroscience

A genetically encoded fluorescent sensor for in vivo imaging of GABA

(2019) Jonathan S. Marvin et al.   NATURE METHODS

Battery-free, fully implantable optofluidic cuff system for wireless optogenetic and pharmacological neuromodulation of peripheral nerves

(2019) Yi Zhang et al.   Science Advances

When Bio Meets Technology: Biohybrid Neural Interfaces

(2019) Amy E. Rochford et al.   ADVANCED MATERIALS

Circularly Permuted Fluorescent Protein-Based Indicators: History, Principles, and Classification

(2019) Alexander I. Kostyuk et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Wireless optofluidic brain probes for chronic neuropharmacology and photostimulation

(2019) Raza Qazi et al.   Nature Biomedical Engineering

An Integrated Brain-Machine Interface Platform With Thousands of Channels

(2019) Elon Musk et al.   JOURNAL OF MEDICAL INTERNET RESEARCH

Distributed coding of choice, action and engagement across the mouse brain

(2019) Nicholas A. Steinmetz et al.   NATURE

Depth-resolved fiber photometry with a single tapered optical fiber implant

(2019) Filippo Pisano et al.   NATURE METHODS

Battery-free, lightweight, injectable microsystem for in vivo wireless pharmacology and optogenetics

(2019) Yi Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluorescent Biosensors for Neurotransmission and Neuromodulation: Engineering and Applications

(2019) Anna V. Leopold et al.   Frontiers in Cellular Neuroscience

Ultrafast Two-Photon Imaging of a High-Gain Voltage Indicator in Awake Behaving Mice

(2019) Vincent Villette et al.   CELL

Sono-optogenetics facilitated by a circulation-delivered rechargeable light source for minimally invasive optogenetics

(2019) Xiang Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wireless, battery-free, fully implantable multimodal and multisite pacemakers for applications in small animal models

(2019) Philipp Gutruf et al.   Nature Communications

Recent Advances in Materials, Devices, and Systems for Neural Interfaces

(2018) Sang Min Won et al.   ADVANCED MATERIALS

High-Density Stretchable Electrode Grids for Chronic Neural Recording

(2018) Klas Tybrandt et al.   ADVANCED MATERIALS

In Vivo Photopharmacology

(2018) Katharina Hüll et al.   CHEMICAL REVIEWS

Optogenetic Induction of Colonic Motility in Mice

(2018) Timothy J. Hibberd et al.   GASTROENTEROLOGY

A genetically encoded fluorescent acetylcholine indicator for in vitro and in vivo studies

(2018) Miao Jing et al.   NATURE BIOTECHNOLOGY

A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters

(2018) Kiryl D. Piatkevich et al.   Nature Chemical Biology

High-speed volumetric imaging of neuronal activity in freely moving rodents

(2018) Oliver Skocek et al.   NATURE METHODS

A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action

(2018) Miriam Stoeber et al.   NEURON

Wireless optoelectronic photometers for monitoring neuronal dynamics in the deep brain

(2018) Luyao Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrafast glutamate sensors resolve high-frequency release at Schaffer collateral synapses

(2018) Nordine Helassa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bright quantum dots emitting at ∼1,600 nm in the NIR-IIb window for deep tissue fluorescence imaging

(2018) Mingxi Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A method for single-neuron chronic recording from the retina in awake mice

(2018) Guosong Hong et al.   SCIENCE

Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors

(2018) Tommaso Patriarchi et al.   SCIENCE

Conducting polymers for neuronal microelectrode array recording and stimulation

(2018) Zaid Aqrawe et al.   SENSORS AND ACTUATORS B-CHEMICAL

Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS

(2018) William H. Zhang et al.   Nature Chemical Biology

Three-photon imaging of mouse brain structure and function through the intact skull

(2018) Tianyu Wang et al.   NATURE METHODS

Aptamer–field-effect transistors overcome Debye length limitations for small-molecule sensing

(2018) Nako Nakatsuka et al.   SCIENCE

Calcium Transient Dynamics of Neural Ensembles in the Primary Motor Cortex of Naturally Behaving Monkeys

(2018) Takahiro Kondo et al.   Cell Reports

Transparent arrays of bilayer-nanomesh microelectrodes for simultaneous electrophysiology and two-photon imaging in the brain

(2018) Yi Qiang et al.   Science Advances

A wireless closed-loop system for optogenetic peripheral neuromodulation

(2018) Aaron D. Mickle et al.   NATURE

Imaging Cortical Dynamics in GCaMP Transgenic Rats with a Head-Mounted Widefield Macroscope

(2018) Benjamin B. Scott et al.   NEURON

Microscale Inorganic LED Based Wireless Neural Systems for Chronic in vivo Optogenetics

(2018) Raza Qazi et al.   Frontiers in Neuroscience

A Neural Probe With Up to 966 Electrodes and Up to 384 Configurable Channels in 0.13 $\mu$m SOI CMOS

(2017) Carolina Mora Lopez et al.   IEEE Transactions on Biomedical Circuits and Systems

Fully integrated silicon probes for high-density recording of neural activity

(2017) James J. Jun et al.   NATURE

Pan-neuronal calcium imaging with cellular resolution in freely swimming zebrafish

(2017) Dal Hyung Kim et al.   NATURE METHODS

Fast high-resolution miniature two-photon microscopy for brain imaging in freely behaving mice

(2017) Weijian Zong et al.   NATURE METHODS

One-step optogenetics with multifunctional flexible polymer fibers

(2017) Seongjun Park et al.   NATURE NEUROSCIENCE

Dynamic illumination of spatially restricted or large brain volumes via a single tapered optical fiber

(2017) Ferruccio Pisanello et al.   NATURE NEUROSCIENCE

Preparation and implementation of optofluidic neural probes for in vivo wireless pharmacology and optogenetics

(2017) Jordan G McCall et al.   Nature Protocols

Flexible Near-Field Wireless Optoelectronics as Subdermal Implants for Broad Applications in Optogenetics

(2017) Gunchul Shin et al.   NEURON

Pyramidal Cell-Interneuron Circuit Architecture and Dynamics in Hippocampal Networks

(2017) Daniel Fine English et al.   NEURON

Fully implantable, battery-free wireless optoelectronic devices for spinal optogenetics

(2017) Vijay K. Samineni et al.   PAIN

Transparent, conformable, active multielectrode array using organic electrochemical transistors

(2017) Wonryung Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Real-time measurement of small molecules directly in awake, ambulatory animals

(2017) Netzahualcóyotl Arroyo-Currás et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aptamer-functionalized neural recording electrodes for the direct measurement of cocaine in vivo

(2017) I. Mitch Taylor et al.   Journal of Materials Chemistry B

State-of-the-art MEMS and microsystem tools for brain research

(2017) John P. Seymour et al.   Microsystems & Nanoengineering

Glial responses to implanted electrodes in the brain

(2017) Joseph W. Salatino et al.   Nature Biomedical Engineering

Optogenetic silencing of nociceptive primary afferents reduces evoked and ongoing bladder pain

(2017) Vijay K. Samineni et al.   Scientific Reports

Analytical Techniques in Neuroscience: Recent Advances in Imaging, Separation, and Electrochemical Methods

(2016) Mallikarjunarao Ganesana et al.   ANALYTICAL CHEMISTRY

Reagentless, Structure-Switching, Electrochemical Aptamer-Based Sensors

(2016) Lauren R. Schoukroun-Barnes et al.   Annual Review of Analytical Chemistry

Close-Packed Silicon Microelectrodes for Scalable Spatially Oversampled Neural Recording

(2016) Jorg Scholvin et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Genetically encoded indicators of neuronal activity

(2016) Michael Z Lin et al.   NATURE NEUROSCIENCE

Wireless Recording in the Peripheral Nervous System with Ultrasonic Neural Dust

(2016) Dongjin Seo et al.   NEURON

DREADDs for Neuroscientists

(2016) Bryan L. Roth   NEURON

The fiber-optic imaging and manipulation of neural activity during animal behavior

(2016) Daisuke Miyamoto et al.   NEUROSCIENCE RESEARCH

FEF inactivation with improved optogenetic methods

(2016) Leah Acker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Guide to Fluorescent Protein FRET Pairs

(2016) Bryce Bajar et al.   SENSORS

Electrochemical sensors and biosensors for determination of catecholamine neurotransmitters: A review

(2016) José A. Ribeiro et al.   TALANTA

Sensitive red protein calcium indicators for imaging neural activity

(2016) Hod Dana et al.   eLife

Materials and technologies for soft implantable neuroprostheses

(2016) Stéphanie P. Lacour et al.   Nature Reviews Materials

Electrochemical Analysis of Neurotransmitters

(2015) Elizabeth S. Bucher et al.   Annual Review of Analytical Chemistry

Wireless Optofluidic Systems for Programmable In Vivo Pharmacology and Optogenetics

(2015) Jae-Woong Jeong et al.   CELL

Recording of brain activity across spatial scales

(2015) CM Lewis et al.   CURRENT OPINION IN NEUROBIOLOGY

A multichannel neural probe with embedded microfluidic channels for simultaneous in vivo neural recording and drug delivery

(2015) Hyunjoo J. Lee et al.   LAB ON A CHIP

Neural probes with multi-drug delivery capability

(2015) Hyogeun Shin et al.   LAB ON A CHIP

Soft, stretchable, fully implantable miniaturized optoelectronic systems for wireless optogenetics

(2015) Sung Il Park et al.   NATURE BIOTECHNOLOGY

Transparent intracortical microprobe array for simultaneous spatiotemporal optical stimulation and multichannel electrical recording

(2015) Joonhee Lee et al.   NATURE METHODS

Wirelessly powered, fully internal optogenetics for brain, spinal and peripheral circuits in mice

(2015) Kate L Montgomery et al.   NATURE METHODS

Arousal and Locomotion Make Distinct Contributions to Cortical Activity Patterns and Visual Encoding

(2015) Martin Vinck et al.   NEURON

Tools for Probing Local Circuits: High-Density Silicon Probes Combined with Optogenetics

(2015) György Buzsáki et al.   NEURON

Monolithically Integrated μLEDs on Silicon Neural Probes for High-Resolution Optogenetic Studies in Behaving Animals

(2015) Fan Wu et al.   NEURON

Electronic dura mater for long-term multimodal neural interfaces

(2015) I. R. Minev et al.   SCIENCE

Wireless magnetothermal deep brain stimulation

(2015) R. Chen et al.   SCIENCE

A high-density, high-channel count, multiplexed μECoG array for auditory-cortex recordings

(2014) Monty A. Escabí et al.   JOURNAL OF NEUROPHYSIOLOGY

Simultaneous all-optical manipulation and recording of neural circuit activity with cellular resolution in vivo

(2014) Adam M Packer et al.   NATURE METHODS

NeuroGrid: recording action potentials from the surface of the brain

(2014) Dion Khodagholy et al.   NATURE NEUROSCIENCE

Multipoint-Emitting Optical Fibers for Spatially Addressable In Vivo Optogenetics

(2014) Ferruccio Pisanello et al.   NEURON

Stretchable Polymeric Multielectrode Array for Conformal Neural Interfacing

(2013) Liang Guo et al.   ADVANCED MATERIALS

Microfabricated Sampling Probes for in Vivo Monitoring of Neurotransmitters

(2013) Woong Hee Lee et al.   ANALYTICAL CHEMISTRY

Opto-μECoG Array: A Hybrid Neural Interface With Transparent μECoG Electrode Array and Integrated LEDs for Optogenetics

(2013) Ki Yong Kwon et al.   IEEE Transactions on Biomedical Circuits and Systems

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

BLA to vHPC Inputs Modulate Anxiety-Related Behaviors

(2013) Ada C. Felix-Ortiz et al.   NEURON

The Inhibitory Circuit Architecture of the Lateral Hypothalamus Orchestrates Feeding

(2013) J. H. Jennings et al.   SCIENCE

Injectable, Cellular-Scale Optoelectronics with Applications for Wireless Optogenetics

(2013) T.-i. Kim et al.   SCIENCE

The origin of extracellular fields and currents — EEG, ECoG, LFP and spikes

(2012) György Buzsáki et al.   NATURE REVIEWS NEUROSCIENCE

Photoactivatable Neuropeptides for Spatiotemporally Precise Delivery of Opioids in Neural Tissue

(2012) Matthew R. Banghart et al.   NEURON

Imaging Calcium in Neurons

(2012) Christine Grienberger et al.   NEURON

Biomaterials-Based Electronics: Polymers and Interfaces for Biology and Medicine

(2012) Meredith Muskovich et al.   Advanced Healthcare Materials

The Development and Application of Optogenetics

(2011) Lief Fenno et al.   Annual Review of Neuroscience

Miniaturized integration of a fluorescence microscope

(2011) Kunal K Ghosh et al.   NATURE METHODS

Flexible, foldable, actively multiplexed, high-density electrode array for mapping brain activity in vivo

(2011) Jonathan Viventi et al.   NATURE NEUROSCIENCE

Regional Slow Waves and Spindles in Human Sleep

(2011) Yuval Nir et al.   NEURON

Optogenetics in Neural Systems

(2011) Ofer Yizhar et al.   NEURON

Understanding the Human Brain

(2011) S. Brenner et al.   SCIENCE

Chemical and Genetic Engineering of Selective Ion Channel-Ligand Interactions

(2011) C. J. Magnus et al.   SCIENCE

Multiwaveguide implantable probe for light delivery to sets of distributed brain targets

(2010) Anthony N. Zorzos et al.   OPTICS LETTERS

Materials and Mechanics for Stretchable Electronics

(2010) J. A. Rogers et al.   SCIENCE

Remote Control of Neuronal Activity in Transgenic Mice Expressing Evolved G Protein-Coupled Receptors

(2009) Georgia M. Alexander et al.   NEURON

Neural Stimulation and Recording Electrodes

(2008) Stuart F. Cogan   Annual Review of Biomedical Engineering

Genetic Dissection of Neural Circuits

(2008) Liqun Luo et al.   NEURON