MiR-21 Simultaneously Regulates ERK1 Signaling in HSC Activation and Hepatocyte EMT in Hepatic Fibrosis

MicroRNA-21 activates hepatic stellate cells via PTEN/Akt signaling

(2013) Jun Wei et al.   BIOMEDICINE & PHARMACOTHERAPY

Perturbation of MicroRNA-370/Lin-28 homolog A/nuclear factor kappa B regulatory circuit contributes to the development of hepatocellular carcinoma

(2013) Wen-Ping Xu et al.   HEPATOLOGY

Circulating MicroRNAs as potential biomarkers for alcoholic steatohepatitis

(2013) Yi-peng Chen et al.   LIVER INTERNATIONAL

Regulation of miRNA-21 by reactive oxygen species-activated ERK/NF-κB in arsenite-induced cell transformation

(2012) Min Ling et al.   FREE RADICAL BIOLOGY AND MEDICINE

Noninvasive Methods to Assess Liver Disease in Patients With Hepatitis B or C

(2012) Laurent Castera   GASTROENTEROLOGY

Inhibitory effects of microRNA 19b in hepatic stellate cell-mediated fibrogenesis

(2012) Ashley M. Lakner et al.   HEPATOLOGY

Hepatic Stellate Cell-derived Delta-like Homolog 1 (DLK1) Protein in Liver Regeneration

(2012) Nian-Ling Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA Damage Induces NF-κB-dependent MicroRNA-21 Up-regulation and Promotes Breast Cancer Cell Invasion

(2012) Jixiao Niu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of platelet-derived growth factor-C and insulin-like growth factor I in hepatic stellate cells is inhibited by miR-29

(2012) Monika Kwiecinski et al.   LABORATORY INVESTIGATION

GW501516-activated PPARβ/δ promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation

(2012) Radina Kostadinova et al.   Cell and Bioscience

microRNA are Central Players in Anti- and Profibrotic Gene Regulation during Liver Fibrosis

(2012) Andrea Noetel et al.   Frontiers in Physiology

Pathogenesis of Liver Fibrosis

(2011) Virginia Hernandez-Gea et al.   Annual Review of Pathology-Mechanisms of Disease

Mechanisms of hepatic fibrogenesis

(2011) Ursula E. Lee et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Sprouty keeps bowel kinases regular in colon cancer, while miR-21 targets Sprouty

(2011) Mark R. Frey et al.   CANCER BIOLOGY & THERAPY

Neurotensin Signaling Activates MicroRNAs-21 and -155 and Akt, Promotes Tumor Growth in Mice, and Is Increased in Human Colon Tumors

(2011) Kyriaki Bakirtzi et al.   GASTROENTEROLOGY

Hedgehog activity, epithelial-mesenchymal transitions, and biliary dysmorphogenesis in biliary atresia

(2011) Alessia Omenetti et al.   HEPATOLOGY

TGF-β-induced miR-21 negatively regulates the antiproliferative activity but has no effect on EMT of TGF-β in HaCaT cells

(2011) Tao Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Intestinal decontamination inhibits TLR4 dependent fibronectin-mediated cross-talk between stellate cells and endothelial cells in liver fibrosis in mice

(2011) Qiang Zhu et al.   JOURNAL OF HEPATOLOGY

A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells

(2011) Kim J. Png et al.   NATURE

Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas

(2011) H-J Kwak et al.   ONCOGENE

MiR-21 Induced Angiogenesis through AKT and ERK Activation and HIF-1α Expression

(2011) Ling-Zhi Liu et al.   PLoS One

MicroRNAs in idiopathic pulmonary fibrosis

(2011) Kusum V. Pandit et al.   Translational Research

Update on hepatic stellate cells: pathogenic role in liver fibrosis and novel isolation techniques

(2011) Frank Tacke et al.   Expert Review of Gastroenterology & Hepatology

Correlation between microRNA expression levels and clinical parameters associated with chronic hepatitis C viral infection in humans

(2010) Rebecca T Marquez et al.   LABORATORY INVESTIGATION

Hepatic fibrosis

(2009) Jingjing Jiao et al.   CURRENT OPINION IN GASTROENTEROLOGY

Hepatocyte nuclear factor 4  attenuates hepatic fibrosis in rats

(2009) H.-Y. Yue et al.   GUT

Inhibition of extracellular signal-regulated kinase 1 by adenovirus mediated small interfering RNA attenuates hepatic fibrosis in rats

(2009) Wei Zhong et al.   HEPATOLOGY

Up-regulation of miR-21 by HER2/neuSignaling Promotes Cell Invasion

(2009) Tzu-Hsuan Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sprouty2 Interacts with Protein Kinase Cδ and Disrupts Phosphorylation of Protein Kinase D1

(2009) Soah Yee Chow et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Raf kinase inhibitor protein inhibits cell proliferation but promotes cell migration in rat hepatic stellate cells

(2009) Junji Ma et al.   LIVER INTERNATIONAL

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways

(2008) Takashi Nitta et al.   HEPATOLOGY

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE