Application of microRNAs in diabetes mellitus

miR-29b as a Therapeutic Agent for Angiotensin II-induced Cardiac Fibrosis by Targeting TGF-β/Smad3 signaling

(2014) Yang Zhang et al.   MOLECULAR THERAPY

The induction of miR-96 by mitochondrial dysfunction causes impaired glycogen synthesis through translational repression of IRS-1 in SK-Hep1 cells

(2013) Hyo-Jin Jeong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Overload Induced Heat Shock Proteins (HSPs), MAPK and miRNA (miR-1 and miR133a) Response in Insulin-Resistant Skeletal Muscle

(2013) Anjaiah Katta et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

miRNA-93 Inhibits GLUT4 and Is Overexpressed in Adipose Tissue of Polycystic Ovary Syndrome Patients and Women With Insulin Resistance

(2013) Y.-H. Chen et al.   DIABETES

Economic Costs of Diabetes in the U.S. in 2012

(2013)   DIABETES CARE

Human adipose microRNA-221 is upregulated in obesity and affects fat metabolism downstream of leptin and TNF-α

(2013) A. Meerson et al.   DIABETOLOGIA

miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes

(2013) X. Zhong et al.   DIABETOLOGIA

Circulating miR-375 as a Biomarker of β-Cell Death and Diabetes in Mice

(2013) Suheda Erener et al.   ENDOCRINOLOGY

miR-200s Contribute to Interleukin-6 (IL-6)-induced Insulin Resistance in Hepatocytes

(2013) Lin Dou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-29b Inhibits Diabetic Nephropathy in db/db Mice

(2013) Hai-Yong Chen et al.   MOLECULAR THERAPY

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b

(2013) Jan-Wilhelm Kornfeld et al.   NATURE

Circulating microRNAs as novel biomarkers for diabetes mellitus

(2013) Claudiane Guay et al.   Nature Reviews Endocrinology

Serum Circulating microRNA Profiling for Identification of Potential Type 2 Diabetes and Obesity Biomarkers

(2013) Nuria Pescador et al.   PLoS One

MicroRNA-494, Upregulated by Tumor Necrosis Factor-α, Desensitizes Insulin Effect in C2C12 Muscle Cells

(2013) Hyunjoo Lee et al.   PLoS One

Regulation of Insulin Secretion in Human Pancreatic Islets

(2012) Patrik Rorsman et al.   Annual Review of Physiology

Plant-derived polyphenols regulate expression of miRNA paralogs miR-103/107 and miR-122 and prevent diet-induced fatty liver disease in hyperlipidemic mice

(2012) Jorge Joven et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

Changes in MicroRNA Expression Contribute to Pancreatic  -Cell Dysfunction in Prediabetic NOD Mice

(2012) E. Roggli et al.   DIABETES

Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivity

(2012) B. Zhou et al.   DIABETOLOGIA

MiRNA-21 Reverses High Glucose and High Insulin Induced Insulin Resistance in 3T3-L1 Adipocytes through Targeting Phosphatase and Tensin Homologue

(2012) H.-y. Ling et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Decrease of microRNA-122 causes hepatic insulin resistance by inducing protein tyrosine phosphatase 1B, which is reversed by licorice flavonoid

(2012) Yoon Mee Yang et al.   HEPATOLOGY

MicroRNAs miR-21a and miR-93 are down regulated in peripheral blood mononuclear cells (PBMCs) from patients with type 1 diabetes

(2012) Francisca Salas-Pérez et al.   IMMUNOBIOLOGY

MicroRNA-30d Induces Insulin Transcription Factor MafA and Insulin Production by Targeting Mitogen-activated Protein 4 Kinase 4 (MAP4K4) in Pancreatic β-Cells

(2012) Xiaomin Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-29 Inhibits Bleomycin-induced Pulmonary Fibrosis in Mice

(2012) Jun Xiao et al.   MOLECULAR THERAPY

MicroRNAs in metabolism and metabolic disorders

(2012) Veerle Rottiers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Lin28/let-7 Axis Regulates Glucose Metabolism

(2011) Hao Zhu et al.   CELL

MicroRNAs in  -Cell Biology, Insulin Resistance, Diabetes and Its Complications

(2011) S. L. Fernandez-Valverde et al.   DIABETES

Increased expression of microRNA miR-326 in type 1 diabetic patients with ongoing islet autoimmunity

(2011) Guido Sebastiani et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Sirt1 and mir-9 expression is regulated during glucose-stimulated insulin secretion in pancreatic β-islets

(2011) Deepti Ramachandran et al.   FEBS Journal

The Sleeping Beauty transposon system: a non-viral vector for gene therapy

(2011) E. L. Aronovich et al.   HUMAN MOLECULAR GENETICS

Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance

(2011) Rui-Hong Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-29a and miR-29b Contribute to Pancreatic  -Cell-Specific Silencing of Monocarboxylate Transporter 1 (Mct1)

(2011) T. J. Pullen et al.   MOLECULAR AND CELLULAR BIOLOGY

MicroRNAs 103 and 107 regulate insulin sensitivity

(2011) Mirko Trajkovski et al.   NATURE

Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism

(2011) Sabine D. Jordan et al.   NATURE CELL BIOLOGY

RNAi-based therapeutic strategies for metabolic disease

(2011) Michael P. Czech et al.   Nature Reviews Endocrinology

The Induction of MicroRNA Targeting IRS-1 Is Involved in the Development of Insulin Resistance under Conditions of Mitochondrial Dysfunction in Hepatocytes

(2011) Hyun Su Ryu et al.   PLoS One

MicroRNA 144 Impairs Insulin Signaling by Inhibiting the Expression of Insulin Receptor Substrate 1 in Type 2 Diabetes Mellitus

(2011) Dwi Setyowati Karolina et al.   PLoS One

Early Second-Trimester Serum MiRNA Profiling Predicts Gestational Diabetes Mellitus

(2011) Chun Zhao et al.   PLoS One

Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs

(2011) R. J. A. Frost et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The microRNA-21-PDCD4 axis prevents type 1 diabetes by blocking pancreatic   cell death

(2011) Q. Ruan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diabetes mellitus, a microRNA-related disease?

(2011) Claudiane Guay et al.   Translational Research

Significance of serum microRNAs in pre-diabetes and newly diagnosed type 2 diabetes: a clinical study

(2010) Lei Kong et al.   ACTA DIABETOLOGICA

Serum microRNA Profiles Serve as Novel Biomarkers for HBV Infection and Diagnosis of HBV-Positive Hepatocarcinoma

(2010) L.-M. Li et al.   CANCER RESEARCH

MicroRNA-223 regulates Glut4 expression and cardiomyocyte glucose metabolism

(2010) Han Lu et al.   CARDIOVASCULAR RESEARCH

Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

(2010) Anna Zampetaki et al.   CIRCULATION RESEARCH

Involvement of MicroRNAs in the Cytotoxic Effects Exerted by Proinflammatory Cytokines on Pancreatic  -Cells

(2010) E. Roggli et al.   DIABETES

The Protective Role of Smad7 in Diabetic Kidney Disease: Mechanism and Therapeutic Potential

(2010) H. Y. Chen et al.   DIABETES

MicroRNA-15a positively regulates insulin synthesis by inhibiting uncoupling protein-2 expression

(2010) Liang-Liang Sun et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes

(2010) B. M. Herrera et al.   DIABETOLOGIA

Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans

(2010) Guo-Kun Wang et al.   EUROPEAN HEART JOURNAL

Expression of Adipose MicroRNAs Is Sensitive to Dietary Conjugated Linoleic Acid Treatment in Mice

(2010) Pilar Parra et al.   PLoS One

MicroRNA expression profiling in diabetic GK rat model

(2009) B. Huang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

MicroRNA-125a is over-expressed in insulin target tissues in a spontaneous rat model of Type 2 Diabetes

(2009) Blanca M Herrera et al.   BMC Medical Genomics

CHANGES IN microRNA (miR) PROFILE AND EFFECTS OF miR-320 IN INSULIN-RESISTANT 3T3-L1 ADIPOCYTES

(2009) Hong-Yan Ling et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

miR-375 maintains normal pancreatic  - and  -cell mass

(2009) M. N. Poy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Up-regulated expression of microRNA-143 in association with obesity in adipose tissue of mice fed high-fat diet

(2008) Rieko Takanabe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs

(2008) Pascal Lovis et al.   BIOLOGICAL CHEMISTRY

miR-375 Targets 3'-Phosphoinositide-Dependent Protein Kinase-1 and Regulates Glucose-Induced Biological Responses in Pancreatic  -Cells

(2008) A. El Ouaamari et al.   DIABETES

Alterations in MicroRNA Expression Contribute to Fatty Acid-Induced Pancreatic  -Cell Dysfunction

(2008) P. Lovis et al.   DIABETES

Kinetics of Rab27a-dependent actions on vesicle docking and priming in pancreatic β-cells

(2008) Matthew J. Merrins et al.   JOURNAL OF PHYSIOLOGY-LONDON

MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene

(2008) Z Lu et al.   ONCOGENE