microRNA-122 regulates hypoxia-inducible factor-1 and vimentin in hepatocytes and correlates with fibrosis in diet-induced steatohepatitis

Molecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte

(2014) Carla Cicchini et al.   LIVER INTERNATIONAL

Hypoxia induces epithelial-mesenchymal transition via activation of SNAI1 by hypoxia-inducible factor -1α in hepatocellular carcinoma

(2013) Lin Zhang et al.   BMC CANCER

Sleep Disorders and the Development of Insulin Resistance and Obesity

(2013) Omar Mesarwi et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

BTB/POZ domain-containing protein 7: Epithelial-mesenchymal transition promoter and prognostic biomarker of hepatocellular carcinoma

(2013) Yi-Ming Tao et al.   HEPATOLOGY

MicroRNAs in liver disease

(2013) Gyongyi Szabo et al.   Nature Reviews Gastroenterology & Hepatology

Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases

(2012) Shashi Bala et al.   HEPATOLOGY

Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver

(2012) Shu-hao Hsu et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis

(2012) Wei-Chih Tsai et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA silencing and the development of novel therapies for liver disease

(2012) Gyongyi Szabo et al.   JOURNAL OF HEPATOLOGY

miR-122 regulates collagen production via targeting hepatic stellate cells and suppressing P4HA1 expression

(2012) Jiang Li et al.   JOURNAL OF HEPATOLOGY

A Feedback Loop Between the Liver-Enriched Transcription Factor Network and Mir-122 Controls Hepatocyte Differentiation

(2011) Ilaria Laudadio et al.   GASTROENTEROLOGY

Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice

(2011) Bharath Nath et al.   HEPATOLOGY

Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice

(2011) Timea Csak et al.   HEPATOLOGY

Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells

(2011) Timea Csak et al.   HEPATOLOGY

Hypoxia and hypoxia inducible factors: Diverse roles in liver diseases

(2011) Bharath Nath et al.   HEPATOLOGY

Circulating MicroRNAs in Patients with Chronic Hepatitis C and Non-Alcoholic Fatty Liver Disease

(2011) Silvia Cermelli et al.   PLoS One

Differential expression of miRNAs in the visceral adipose tissue of patients with non-alcoholic fatty liver disease

(2010) M. Estep et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Role of lysyl oxidase in myocardial fibrosis: from basic science to clinical aspects

(2010) Begoña López et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

A novel GSK-3 beta-C/EBP alpha-miR-122-insulin-like growth factor 1 receptor regulatory circuitry in human hepatocellular carcinoma

(2010) Chunxian Zeng et al.   HEPATOLOGY

Correlation between microRNA expression levels and clinical parameters associated with chronic hepatitis C viral infection in humans

(2010) Rebecca T Marquez et al.   LABORATORY INVESTIGATION

Hypoxia stimulates hepatocyte epithelial to mesenchymal transition by hypoxia-inducible factor and transforming growth factor-β-dependent mechanisms

(2010) Bryan L. Copple   LIVER INTERNATIONAL

microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma

(2010) Julja Burchard et al.   Molecular Systems Biology

MicroRNA Expression Profile in Lieber-DeCarli Diet-Induced Alcoholic and Methionine Choline Deficient Diet-Induced Nonalcoholic Steatohepatitis Models in Mice

(2009) Angela Dolganiuc et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Reduced liver fibrosis in hypoxia-inducible factor-1α-deficient mice

(2009) Jeon-OK Moon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

MEKK3 is required for lysophosphatidic acid-induced NF-κB activation

(2009) Wenjing Sun et al.   CELLULAR SIGNALLING

Vitamin C deficiency attenuates liver fibrosis by way of up-regulated peroxisome proliferator-activated receptor-gamma expression in senescence marker protein 30 knockout mice

(2009) Jin-Kyu Park et al.   HEPATOLOGY

Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice

(2009) Bo Wang et al.   HEPATOLOGY

Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis

(2009) Rafal P. Witek et al.   HEPATOLOGY

Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice

(2009) Kojiro Taura et al.   HEPATOLOGY

Hypoxia-Inducible Factor 1  Induces Fibrosis and Insulin Resistance in White Adipose Tissue

(2009) N. Halberg et al.   MOLECULAR AND CELLULAR BIOLOGY

TGFβ-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3

(2009) B Wang et al.   ONCOGENE

Position-Dependent Function for a Tandem MicroRNA miR-122-Binding Site Located in the Hepatitis C Virus RNA Genome

(2008) Catherine L. Jopling et al.   Cell Host & Microbe

MEKK3 Initiates Transforming Growth Factor β 2 –Dependent Epithelial-to-Mesenchymal Transition During Endocardial Cushion Morphogenesis

(2008) Mark V. Stevens et al.   CIRCULATION RESEARCH

Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression

(2008) Onpan Cheung et al.   HEPATOLOGY