Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver

Foxa1 and Foxa2 Are Essential for Sexual Dimorphism in Liver Cancer

(2012) Zhaoyu Li et al.   CELL

Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage

(2011) S. I. Grivennikov et al.   ANNALS OF THE RHEUMATIC DISEASES

A Feedback Loop Between the Liver-Enriched Transcription Factor Network and Mir-122 Controls Hepatocyte Differentiation

(2011) Ilaria Laudadio et al.   GASTROENTEROLOGY

Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury

(2011) Christer Baeck et al.   GUT

Hepatocyte growth factor/c-metsignaling is required for stem-cell-mediated liver regeneration in mice

(2011) Tsuyoshi Ishikawa et al.   HEPATOLOGY

Tumor Promotion via Injury- and Death-Induced Inflammation

(2011) Ali Kuraishy et al.   IMMUNITY

NKp46 identifies an NKT cell subset susceptible to leukemic transformation in mouse and human

(2011) Jianhua Yu et al.   JOURNAL OF CLINICAL INVESTIGATION

CPEB and two poly(A) polymerases control miR-122 stability and p53 mRNA translation

(2011) David M. Burns et al.   NATURE

Hepatocellular Carcinoma

(2011) Hashem B. El-Serag   NEW ENGLAND JOURNAL OF MEDICINE

MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma

(2011) Kentaro Kojima et al.   Nature Communications

Gankyrin plays an essential role in Ras-induced tumorigenesis through regulation of the RhoA/ROCK pathway in mammalian cells

(2010) Jiang-Hong Man et al.   JOURNAL OF CLINICAL INVESTIGATION

Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

(2009) Janaiah Kota et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Disruption of Dicer1 Induces Dysregulated Fetal Gene Expression and Promotes Hepatocarcinogenesis

(2009) Shigeki Sekine et al.   GASTROENTEROLOGY

Integration of microRNA miR-122 in hepatic circadian gene expression

(2009) D. Gatfield et al.   GENES & DEVELOPMENT

Loss of protein kinase Cβ function protects mice against diet-induced obesity and development of hepatic steatosis and insulin resistance

(2009) Wei Huang et al.   HEPATOLOGY

Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice

(2009) Bo Wang et al.   HEPATOLOGY

MicroRNA-122 Inhibits Tumorigenic Properties of Hepatocellular Carcinoma Cells and Sensitizes These Cells to Sorafenib

(2009) Shoumei Bai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatocellular Carcinoma Incidence, Mortality, and Survival Trends in the United States From 1975 to 2005

(2009) Sean F. Altekruse et al.   JOURNAL OF CLINICAL ONCOLOGY

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

(2009) R. E. Lanford et al.   SCIENCE

Hepatic Steatosis in Leptin-Deficient Mice Is Promoted by the PPARγ Target Gene Fsp27

(2008) Kimihiko Matsusue et al.   Cell Metabolism

EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features

(2008) Taro Yamashita et al.   GASTROENTEROLOGY

Proteomic profiling reveals the prognostic value of adenomatous polyposis coli-end-binding protein 1 in hepatocellular carcinoma

(2008) Tatsuya Orimo et al.   HEPATOLOGY

Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression

(2008) Onpan Cheung et al.   HEPATOLOGY

Hepatic function is preserved in the absence of mature microRNAs

(2008) Nicholas J. Hand et al.   HEPATOLOGY

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE

Detecting microRNA binding and siRNA off-target effects from expression data

(2008) Stijn van Dongen et al.   NATURE METHODS

Molecular Mechanisms and Therapeutic Targets in Steatosis and Steatohepatitis

(2008) N. Anderson et al.   PHARMACOLOGICAL REVIEWS

Chemokine-directed immune cell infiltration in acute and chronic liver disease

(2008) Karlin Raja Karlmark et al.   Expert Review of Gastroenterology & Hepatology