Brain astrocytes and microglia express functional MR1 molecules that present microbial antigens to mucosal-associated invariant T (MAIT) cells

Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson’s disease brain

(2020) Jinar Rostami et al.   Journal of Neuroinflammation

Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity

(2020) Amine Toubal et al.   Nature Communications

Casting a wider net: Immunosurveillance by nonclassical MHC molecules

(2019) M. Patricia D’Souza et al.   PLoS Pathogens

Innate, innate-like and adaptive lymphocytes in the pathogenesis of MS and EAE

(2019) Luc Van Kaer et al.   Cellular & Molecular Immunology

Expression of CD 1d by astrocytes corresponds with relative activity in multiple sclerosis lesions

(2019) Fraser G. W. Muir et al.   BRAIN PATHOLOGY

The role of microglia in viral encephalitis: a review

(2019) Zhuangzhuang Chen et al.   Journal of Neuroinflammation

The Response to Stimulation in Neurons and Astrocytes

(2019) Inés Juaristi et al.   NEUROCHEMICAL RESEARCH

The biology and functional importance of MAIT cells

(2019) Dale I. Godfrey et al.   NATURE IMMUNOLOGY

Molecular mechanisms of lineage decisions in metabolite-specific T cells

(2019) François Legoux et al.   NATURE IMMUNOLOGY

Microbial metabolites control the thymic development of mucosal-associated invariant T cells

(2019) François Legoux et al.   SCIENCE

Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality

(2019) Timothy S.C. Hinks et al.   Cell Reports

Type I interferons are important co‐stimulatory signals during T cell receptor mediated human MAIT cell activation

(2019) Rajesh Lamichhane et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

MR1-Independent Activation of Human Mucosal-Associated Invariant T Cells by Mycobacteria

(2019) Sara Suliman et al.   JOURNAL OF IMMUNOLOGY

MR1 antigen presentation to MAIT cells: new ligands, diverse pathways?

(2018) Hamish EG McWilliam et al.   CURRENT OPINION IN IMMUNOLOGY

Immune evasion of the CD1d/NKT cell axis

(2018) Randy R Brutkiewicz et al.   CURRENT OPINION IN IMMUNOLOGY

Human blood MAIT cell subsets defined using MR1 tetramers

(2018) Nicholas A Gherardin et al.   IMMUNOLOGY AND CELL BIOLOGY

Microglia-Astrocyte Crosstalk: An Intimate Molecular Conversation

(2018) Mithilesh Kumar Jha et al.   NEUROSCIENTIST

MAIT cells are activated in acute Dengue virus infection and after in vitro Zika virus infection

(2018) Dominic Paquin-Proulx et al.   PLoS Neglected Tropical Diseases

A common transcriptomic program acquired in the thymus defines tissue residency of MAIT and NKT subsets

(2018) Marion Salou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Blood-Brain Barrier: From Physiology to Disease and Back

(2018) Melanie D. Sweeney et al.   PHYSIOLOGICAL REVIEWS

MR1-dependent antigen presentation

(2018) Elham Karamooz et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

MAIT cells contribute to protection against lethal influenza infection in vivo

(2018) Bonnie van Wilgenburg et al.   Nature Communications

The Toll-like receptor 9 signalling pathway regulates MR1-mediated bacterial antigen presentation in B cells

(2017) Jianyun Liu et al.   IMMUNOLOGY

TLR signaling in human antigen-presenting cells regulates MR1-dependent activation of MAIT cells

(2016) James E. Ussher et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mucosal-associated invariant T cells in autoimmunity, immune-mediated diseases and airways disease

(2016) Timothy S. C. Hinks   IMMUNOLOGY

Biliary epithelium and liver B cells exposed to bacteria activate intrahepatic MAIT cells through MR1

(2016) Hannah C. Jeffery et al.   JOURNAL OF HEPATOLOGY

Neuroinflammation: the devil is in the details

(2016) Damon J. DiSabato et al.   JOURNAL OF NEUROCHEMISTRY

Expression and alternative splicing of classical and nonclassical MHCI genes in the hippocampus and neuromuscular junction

(2016) Mazell M. Tetruashvily et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18–dependent activation

(2016) Liyen Loh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers

(2015) Azad Rahimpour et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Spatial–Temporal Expression of Non-classical MHC Class I Molecules in the C57 Mouse Brain

(2015) Jiane Liu et al.   NEUROCHEMICAL RESEARCH

Viral immune evasion: Lessons in MHC class I antigen presentation

(2015) Michael L. van de Weijer et al.   SEMINARS IN IMMUNOLOGY

Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection

(2015) Edwin Leeansyah et al.   PLoS Pathogens

CD8+MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL-18 serum levels in multiple sclerosis

(2014) Anne Willing et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets

(2014) A Kurioka et al.   Mucosal Immunology

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

(2014) Alexandra J. Corbett et al.   NATURE

Intravascular staining for discrimination of vascular and tissue leukocytes

(2014) Kristin G Anderson et al.   Nature Protocols

The Adaptable Major Histocompatibility Complex (MHC) Fold: Structure and Function of Nonclassical and MHC Class I–Like Molecules

(2013) Erin J. Adams et al.   Annual Review of Immunology

MAIT Cells Detect and Efficiently Lyse Bacterially-Infected Epithelial Cells

(2013) Lionel Le Bourhis et al.   PLoS Pathogens

MR1 presents microbial vitamin B metabolites to MAIT cells

(2012) Lars Kjer-Nielsen et al.   NATURE

How do immune cells overcome the blood-brain barrier in multiple sclerosis?

(2011) Catherine Larochelle et al.   FEBS LETTERS

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells

(2010) M. Dusseaux et al.   BLOOD

Antimicrobial activity of mucosal-associated invariant T cells

(2010) Lionel Le Bourhis et al.   NATURE IMMUNOLOGY

Human Mucosal Associated Invariant T Cells Detect Bacterially Infected Cells

(2010) Marielle C. Gold et al.   PLOS BIOLOGY

Invariant V 7.2-J 33 TCR is expressed in human kidney and brain tumors indicating infiltration by mucosal-associated invariant T (MAIT) cells

(2008) A. Peterfalvi et al.   INTERNATIONAL IMMUNOLOGY