MR1-Independent Activation of Human Mucosal-Associated Invariant T Cells by Mycobacteria

Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions

(2019) Maria Gutierrez-Arcelus et al.   Nature Communications

Select sequencing of clonally expanded CD8+ T cells reveals limits to clonal expansion

(2019) Huang Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Call for Blood—In Human Immunology

(2019) Petter Brodin et al.   IMMUNITY

Human blood MAIT cell subsets defined using MR1 tetramers

(2018) Nicholas A Gherardin et al.   IMMUNOLOGY AND CELL BIOLOGY

An overview on the identification of MAIT cell antigens

(2018) Lars Kjer-Nielsen et al.   IMMUNOLOGY AND CELL BIOLOGY

MAIT cells and microbial immunity

(2018) Erin W Meermeier et al.   IMMUNOLOGY AND CELL BIOLOGY

MAIT cell clonal expansion and TCR repertoire shaping in human volunteers challenged with Salmonella Paratyphi A

(2018) Lauren J. Howson et al.   Nature Communications

Limited pulmonary mucosal-associated invariant T cell accumulation and activation during Mycobacterium tuberculosis infection in rhesus macaques

(2018) Keith D. Kauffman et al.   INFECTION AND IMMUNITY

The CD4−CD8− MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8+ MAIT cell pool

(2018) Joana Dias et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantifiable predictive features define epitope-specific T cell receptor repertoires

(2017) Pradyot Dash et al.   NATURE

Identifying specificity groups in the T cell receptor repertoire

(2017) Jacob Glanville et al.   NATURE

Polyfunctional CD4+ T Cells As Targets for Tuberculosis Vaccination

(2017) Deborah A. Lewinsohn et al.   Frontiers in Immunology

Antigen Export Reduces Antigen Presentation and Limits T Cell Control of M. tuberculosis

(2016) Smita Srivastava et al.   Cell Host & Microbe

Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition

(2016) Nicholas A. Gherardin et al.   IMMUNITY

Bacillus Calmette–Guérin (BCG) Revaccination of Adults with LatentMycobacterium tuberculosisInfection Induces Long-Lived BCG-Reactive NK Cell Responses

(2016) Sara Suliman et al.   JOURNAL OF IMMUNOLOGY

Vaccination Against Tuberculosis With Whole-Cell Mycobacterial Vaccines

(2016) Thomas J. Scriba et al.   JOURNAL OF INFECTIOUS DISEASES

Human MAIT-cell responses to Escherichia coli : activation, cytokine production, proliferation, and cytotoxicity

(2016) Joana Dias et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A blood RNA signature for tuberculosis disease risk: a prospective cohort study

(2016) Daniel E Zak et al.   LANCET

MR1-restricted mucosal-associated invariant T (MAIT) cells respond to mycobacterial vaccination and infection in nonhuman primates

(2016) J M Greene et al.   Mucosal Immunology

T-cell activation is an immune correlate of risk in BCG vaccinated infants

(2016) Helen A. Fletcher et al.   Nature Communications

Human TRAV1-2-negative MR1-restricted T cells detect S. pyogenes and alternatives to MAIT riboflavin-based antigens

(2016) Erin W. Meermeier et al.   Nature Communications

MAIT cells are activated during human viral infections

(2016) Bonnie van Wilgenburg et al.   Nature Communications

Immunometabolic Pathways in BCG-Induced Trained Immunity

(2016) Rob J.W. Arts et al.   Cell Reports

The Global Burden of Latent Tuberculosis Infection: A Re-estimation Using Mathematical Modelling

(2016) Rein M. G. J. Houben et al.   PLOS MEDICINE

On the impact of masking and blocking hypotheses for measuring the efficacy of new tuberculosis vaccines

(2016) Sergio Arregui et al.   PeerJ

T-cell receptor repertoire of human peripheral CD161hiTRAV1-2+ MAIT cells revealed by next generation sequencing and single cell analysis

(2015) Kathrin Held et al.   HUMAN IMMUNOLOGY

MR1-restricted mucosal associated invariant T (MAIT) cells in the immune response toMycobacterium tuberculosis

(2015) Marielle C. Gold et al.   IMMUNOLOGICAL REVIEWS

High expression of CD26 accurately identifies human bacteria-reactive MR1-restricted MAIT cells

(2015) Prabhat K. Sharma et al.   IMMUNOLOGY

Qualification of a whole blood intracellular cytokine staining assay to measure mycobacteria-specific CD4 and CD8 T cell immunity by flow cytometry

(2015) Benjamin M. Kagina et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites

(2015) Isaac G. Sakala et al.   JOURNAL OF IMMUNOLOGY

The burgeoning family of unconventional T cells

(2015) Dale I Godfrey et al.   NATURE IMMUNOLOGY

Trained immunity: consequences for the heterologous effects of BCG vaccination

(2015) J. Kleinnijenhuis et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Mucosal-associated invariant T cells are numerically and functionally deficient in patients with mycobacterial infection and reflect disease activity

(2015) Yong-Soo Kwon et al.   TUBERCULOSIS

MR1-Restricted Mucosal-Associated Invariant T Cells and Their Activation during Infectious Diseases

(2015) Lauren J. Howson et al.   Frontiers in Immunology

MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage

(2014) Marielle C. Gold et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bacillus Calmette-Guerin Vaccination of Human Newborns Induces T Cells with Complex Cytokine and Phenotypic Profiles

(2014) A. P. Soares et al.   JOURNAL OF IMMUNOLOGY

Maturation of Innate Responses to Mycobacteria over the First Nine Months of Life

(2014) M. S. Shey et al.   JOURNAL OF IMMUNOLOGY

Delaying BCG Vaccination Until 8 Weeks of Age Results in Robust BCG-Specific T-Cell Responses in HIV-Exposed Infants

(2014) Christophe Toukam Tchakoute et al.   JOURNAL OF INFECTIOUS DISEASES

MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets

(2014) A Kurioka et al.   Mucosal Immunology

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

(2014) Alexandra J. Corbett et al.   NATURE

Linking T-cell receptor sequence to functional phenotype at the single-cell level

(2014) Arnold Han et al.   NATURE BIOTECHNOLOGY

Safety and reactogenicity of BCG revaccination with isoniazid pretreatment in TST positive adults

(2014) Mark Hatherill et al.   VACCINE

Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRβ repertoire

(2014) Marco Lepore et al.   Nature Communications

CD161 Defines a Transcriptional and Functional Phenotype across Distinct Human T Cell Lineages

(2014) Joannah R. Fergusson et al.   Cell Reports

Protection by BCG Vaccine Against Tuberculosis: A Systematic Review of Randomized Controlled Trials

(2013) Punam Mangtani et al.   CLINICAL INFECTIOUS DISEASES

CD161++CD8+T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner

(2013) James E. Ussher et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Longitudinal Changes in CD4+ T-Cell Memory Responses Induced by BCG Vaccination of Newborns

(2013) Andreia P. Soares, Cheong K. C. Kwong Chung, Terry Choice, E. Jane Hughes, Gail Jacobs, Esme Janse van Rensburg, Gloria Khomba, Marwou de Kock, Lesedi Lerumo, Lebohang Makhethe, Mbulelo H. Maneli, Bernadette Pienaar, Erica Smit, Nontobeko G. Tena-Coki, Leandre van Wyk, W. Henry Boom et al.   JOURNAL OF INFECTIOUS DISEASES

MR1 presents microbial vitamin B metabolites to MAIT cells

(2012) Lars Kjer-Nielsen et al.   NATURE

Human MAIT and CD8   cells develop from a pool of type-17 precommitted CD8+ T cells

(2011) L. J. Walker et al.   BLOOD

SPICE: Exploration and analysis of post-cytometric complex multivariate datasets

(2011) Mario Roederer et al.   CYTOMETRY PART A

The Tuberculin Skin Test versus QuantiFERON TB Gold® in Predicting Tuberculosis Disease in an Adolescent Cohort Study in South Africa

(2011) Hassan Mahomed et al.   PLoS One

Specific T Cell Frequency and Cytokine Expression Profile Do Not Correlate with Protection against Tuberculosis after Bacillus Calmette-Guérin Vaccination of Newborns

(2010) Benjamin M. N. Kagina et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Antimicrobial activity of mucosal-associated invariant T cells

(2010) Lionel Le Bourhis et al.   NATURE IMMUNOLOGY

Human Mucosal Associated Invariant T Cells Detect Bacterially Infected Cells

(2010) Marielle C. Gold et al.   PLOS BIOLOGY