The role of microglia in viral encephalitis: a review

Microglial nodules provide the environment for pathogenic T cells in human encephalitis

(2019) Anna R. Tröscher et al.   ACTA NEUROPATHOLOGICA

Microglia control the spread of neurotropic virus infection via P2Y12 signalling and recruit monocytes through P2Y12-independent mechanisms

(2018) Rebeka Fekete et al.   ACTA NEUROPATHOLOGICA

Expression profiling suggests microglial impairment in human immunodeficiency virus neuropathogenesis

(2018) Stephen D. Ginsberg et al.   ANNALS OF NEUROLOGY

Inflammation-Induced, STING-Dependent Autophagy Restricts Zika Virus Infection in the Drosophila Brain

(2018) Yuan Liu et al.   Cell Host & Microbe

Microglia are required for protection against lethal coronavirus encephalitis in mice

(2018) D. Lori Wheeler et al.   JOURNAL OF CLINICAL INVESTIGATION

Alzheimer’s Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection

(2018) William A. Eimer et al.   NEURON

Peli1 facilitates virus replication and promotes neuroinflammation during West Nile virus infection

(2018) Huanle Luo et al.   JOURNAL OF CLINICAL INVESTIGATION

Acute Viral Encephalitis

(2018) Kenneth L. Tyler   NEW ENGLAND JOURNAL OF MEDICINE

Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis

(2018) Chintan Chhatbar et al.   Cell Reports

Myeloid Cells in the Central Nervous System

(2017) Jasmin Herz et al.   IMMUNITY

Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection

(2017) Brian P. Daniels et al.   JOURNAL OF CLINICAL INVESTIGATION

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease

(2017) Carmen Venegas et al.   NATURE

Role of Interleukin-10 in Acute Brain Injuries

(2017) Joshua M. Garcia et al.   Frontiers in Neurology

Microcephaly associated with maternal Zika virus infection

(2016) AF Moron et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Signal Integration by the IκB Protein Pickle Shapes Drosophila Innate Host Defense

(2016) Otto Morris et al.   Cell Host & Microbe

Microglial Physiology and Pathophysiology: Insights from Genome-wide Transcriptional Profiling

(2016) Andrea Crotti et al.   IMMUNITY

Protective Effect of Amyloid-β Peptides Against Herpes Simplex Virus-1 Infection in a Neuronal Cell Culture Model

(2016) Karine Bourgade et al.   JOURNAL OF ALZHEIMERS DISEASE

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

(2016) Yaming Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study

(2016) Van-Mai Cao-Lormeau et al.   LANCET

A complement–microglial axis drives synapse loss during virus-induced memory impairment

(2016) Michael J. Vasek et al.   NATURE

Sall1 is a transcriptional regulator defining microglia identity and function

(2016) Anne Buttgereit et al.   NATURE IMMUNOLOGY

Microglial brain region−dependent diversity and selective regional sensitivities to aging

(2016) Kathleen Grabert et al.   NATURE NEUROSCIENCE

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy

(2016) Peng Yuan et al.   NEURON

Zika Virus Infection in Pregnant Women in Rio de Janeiro

(2016) Patrícia Brasil et al.   NEW ENGLAND JOURNAL OF MEDICINE

Zika Virus Associated with Microcephaly

(2016) Jernej Mlakar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Zika Virus and Birth Defects — Reviewing the Evidence for Causality

(2016) Sonja A. Rasmussen et al.   NEW ENGLAND JOURNAL OF MEDICINE

The brain parenchyma has a type I interferon response that can limit virus spread

(2016) Eugene Drokhlyansky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

Sensing of HSV-1 by the cGAS–STING pathway in microglia orchestrates antiviral defence in the CNS

(2016) Line S. Reinert et al.   Nature Communications

Microglia–blood vessel interactions: a double-edged sword in brain pathologies

(2015) Nevenka Dudvarski Stankovic et al.   ACTA NEUROPATHOLOGICA

Neuroinflammatory TNFα Impairs Memory via Astrocyte Signaling

(2015) Samia Habbas et al.   CELL

RIP1/RIP3 Binding to HSV-1 ICP6 Initiates Necroptosis to Restrict Virus Propagation in Mice

(2015) Zhe Huang et al.   Cell Host & Microbe

Functional IRF3 deficiency in a patient with herpes simplex encephalitis

(2015) Line Lykke Andersen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activation and Regulation of DNA-Driven Immune Responses

(2015) Søren R. Paludan   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

New insights into innate immune restriction of West Nile virus infection

(2015) Helen M Lazear et al.   Current Opinion in Virology

Decreased neuronal autophagy in HIV dementia: A mechanism of indirect neurotoxicity

(2014) Mehrdad Alirezaei et al.   Autophagy

Sublime Microglia: Expanding Roles for the Guardians of the CNS

(2014) Michael W. Salter et al.   CELL

Antiviral Autophagy Restricts Rift Valley Fever Virus Infection and Is Conserved from Flies to Mammals

(2014) Ryan H. Moy et al.   IMMUNITY

The Parasitophorous Vacuole Membrane of Toxoplasma gondii Is Targeted for Disruption by Ubiquitin-like Conjugation Systems of Autophagy

(2014) Jayoung Choi et al.   IMMUNITY

Differential roles of microglia and monocytes in the inflamed central nervous system

(2014) Ryo Yamasaki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3

(2014) Huayi Wang et al.   MOLECULAR CELL

Burden of encephalitis-associated hospitalizations in the United States, 1998-2010

(2014) N. M. Vora et al.   NEUROLOGY

Encephalitis Hospitalization Rates and Inpatient Mortality in the United States, 2000-2010

(2014) Benjamin P. George et al.   PLoS One

Viral Pathogen-Associated Molecular Patterns Regulate Blood-Brain Barrier Integrity via Competing Innate Cytokine Signals

(2014) B. P. Daniels et al.   mBio

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

Immune Sensing of DNA

(2013) Søren R. Paludan et al.   IMMUNITY

Cytosolic Sensing of Viruses

(2013) Delphine Goubau et al.   IMMUNITY

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

(2013) Stephanie M Pyonteck et al.   NATURE MEDICINE

Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation

(2013) Yichuan Xiao et al.   NATURE MEDICINE

The microglial sensome revealed by direct RNA sequencing

(2013) Suzanne E Hickman et al.   NATURE NEUROSCIENCE

Microglia: Scapegoat, Saboteur, or Something Else?

(2013) A. Aguzzi et al.   SCIENCE

Development and homeostasis of “resident” myeloid cells: The case of the microglia

(2012) Elisa Gomez Perdiguero et al.   GLIA

Regulation of microglia development and homeostasis

(2012) Melanie Greter et al.   GLIA

Stroma-Derived Interleukin-34 Controls the Development and Maintenance of Langerhans Cells and the Maintenance of Microglia

(2012) Melanie Greter et al.   IMMUNITY

Virus Recognition by Toll-7 Activates Antiviral Autophagy in Drosophila

(2012) Margaret Nakamoto et al.   IMMUNITY

Chikungunya virus–induced autophagy delays caspase-dependent cell death

(2012) Pierre-Emmanuel Joubert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages

(2012) Daniel R Getts et al.   Journal of Neuroinflammation

STING and the innate immune response to nucleic acids in the cytosol

(2012) Dara L Burdette et al.   NATURE IMMUNOLOGY

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

(2012) L. Sun et al.   SCIENCE

Capture, crawl, cross: the T cell code to breach the blood–brain barriers

(2012) Britta Engelhardt et al.   TRENDS IN IMMUNOLOGY

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

(2011) Marco Prinz et al.   NATURE NEUROSCIENCE

TNFα Controls Glutamatergic Gliotransmission in the Hippocampal Dentate Gyrus

(2011) Mirko Santello et al.   NEURON

γ-Secretase component presenilin is important for microglia β-amyloid clearance

(2010) Dorit Farfara et al.   ANNALS OF NEUROLOGY

Microglia Activation and Anti-inflammatory Regulation in Alzheimer’s Disease

(2010) Lih-Fen Lue et al.   MOLECULAR NEUROBIOLOGY

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

Persistent neuropsychological impairment associated with West Nile virus infection

(2009) Joseph R. Sadek et al.   JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY