Review of aromatherapy essential oils and their mechanism of action against migraines

Transcriptome analysis of Botrytis cinerea in response to tea tree oil and its two characteristic components

(2020) Zhenbiao Li et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Microglia P2X4R-BDNF signalling contributes to central sensitization in a recurrent nitroglycerin-induced chronic migraine model

(2020) Ting Long et al.   JOURNAL OF HEADACHE AND PAIN

Determination of Organosulfides from Onion Oil

(2020) Maranda S. Cantrell et al.   Foods

Determination of toosendanin and trans ‐anethole in Fructus Meliae Toosendan and Fructus Foeniculi by HPLC–MS/MS and GC–MS/MS in rat plasma and their potential herb–herb interactions

(2020) Jiaoyan Yu et al.   BIOMEDICAL CHROMATOGRAPHY

β-Caryophyllene, a Natural Sesquiterpene, Attenuates Neuropathic Pain and Depressive-Like Behavior in Experimental Diabetic Mice

(2019) Dalia Samanta Aguilar-Ávila et al.   JOURNAL OF MEDICINAL FOOD

d-Limonene protects PC12 cells against corticosterone-induced neurotoxicity by activating the AMPK pathway

(2019) Xue-ping Tang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Gepants for the treatment of migraine

(2019) Andrea Negro et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Efficacy of Anise (Pimpinella anisum L.) oil for migraine headache: A pilot randomized placebo-controlled clinical trial

(2019) Seyed Hamdollah Mosavat et al.   JOURNAL OF ETHNOPHARMACOLOGY

Microglial NLRP3 inflammasome activation mediates IL-1β release and contributes to central sensitization in a recurrent nitroglycerin-induced migraine model

(2019) Wei He et al.   Journal of Neuroinflammation

Attenuating effect of α‐pinene on neurobehavioural deficit, oxidative damage and inflammatory response following focal ischaemic stroke in rat

(2019) Mahdieh Khoshnazar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Compositional analysis of the essential oil of Boswellia dalzielii frankincense from West Africa reveals two major chemotypes

(2019) Anjanette DeCarlo et al.   PHYTOCHEMISTRY

Aspirin in the Treatment and Prevention of Migraine Headaches: Possible Additional Clinical Options for Primary Healthcare Providers

(2019) Bianca Biglione et al.   AMERICAN JOURNAL OF MEDICINE

Identification of a pro-elongation effect of diallyl disulfide, a major organosulfur compound in garlic oil, on microglial process

(2019) Xing Xu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

β-Caryophyllene (BCP) ameliorates MPP+ induced cytotoxicity

(2018) Guifang Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition

(2018)   CEPHALALGIA

The Role of Endothelin in the Pathophysiology of Migraine—a Systematic Review

(2018) Afrim Iljazi et al.   Current Pain and Headache Reports

β-elemene attenuates macrophage activation and proinflammatory factor production via crosstalk with Wnt/β-catenin signaling pathway

(2018) Yangyi Fang et al.   FITOTERAPIA

Linalyl acetate restores endothelial dysfunction and hemodynamic alterations in diabetic rats exposed to chronic immobilization stress

(2018) You Kyoung Shin et al.   JOURNAL OF APPLIED PHYSIOLOGY

GC–MS method for determination and pharmacokinetic study of seven volatile constituents in rat plasma after oral administration of the essential oil of Rhizoma Curcumae

(2018) Wenjing Li et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Illness perception in patients with migraine: An exploratory study in a tertiary care headache centre

(2018) Laura Sirri et al.   JOURNAL OF PSYCHOSOMATIC RESEARCH

Hydroxyl Group and Vasorelaxant Effects of Perillyl Alcohol, Carveol, Limonene on Aorta Smooth Muscle of Rats

(2018) Ana Cardoso-Teixeira et al.   MOLECULES

The serum level of inflammatory markers in chronic and episodic migraine: a case-control study

(2018) Fahimeh Martami et al.   NEUROLOGICAL SCIENCES

Evaluation of the effect of topical chamomile (Matricaria chamomilla L.) oleogel as pain relief in migraine without aura: a randomized, double-blind, placebo-controlled, crossover study

(2018) Arman Zargaran et al.   NEUROLOGICAL SCIENCES

Targeted Nitric Oxide Synthase Inhibitors for Migraine

(2018) Amynah A. Pradhan et al.   Neurotherapeutics

Transcriptome analysis and identification of genes related to terpenoid biosynthesis in Cinnamomum camphora

(2018) Caihui Chen et al.   BMC GENOMICS

Local Delivery of β-Elemene Improves Locomotor Functional Recovery by Alleviating Endoplasmic Reticulum Stress and Reducing Neuronal Apoptosis in Rats with Spinal Cord Injury

(2018) Jingyu Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The neuroprotective effects and probable mechanisms of Ligustilide and its degradative products on intracerebral hemorrhage in mice

(2018) Li Han et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

β-Caryophyllene, the major constituent of copaiba oil, reduces systemic inflammation and oxidative stress in arthritic rats

(2018) Ana P. Ames-Sibin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Beta-caryophyllene protects against diet-induced dyslipidemia and vascular inflammation in rats: Involvement of CB2 and PPAR-γ receptors

(2018) Dareen A. Youssef et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Coriander essential oil and linalool - interactions with antibiotics against Gram-positive and Gram-negative bacteria

(2018) P. Aelenei et al.   LETTERS IN APPLIED MICROBIOLOGY

Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice

(2018) Bing Wang et al.   NEUROCHEMICAL RESEARCH

Trans-caryophyllene inhibits amyloid β (Aβ) oligomer-induced neuroinflammation in BV-2 microglial cells

(2017) Yawei Hu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Chemical Composition and Antimigraine Activity of Essential Oil of Angelicae dahuricae Radix

(2017) Jingbo Sun et al.   JOURNAL OF MEDICINAL FOOD

Silver ion coordination countercurrent chromatography: Separation of β-elemene from the volatile oil of Curcumae Rhizoma

(2017) Mengxia Lu et al.   JOURNAL OF SEPARATION SCIENCE

Limonene reduces hyperalgesia induced by gp120 and cytokines by modulation of IL-1 β and protein expression in spinal cord of mice

(2017) Ana Claudia Piccinelli et al.   LIFE SCIENCES

Influence of drying methods on chemical compositions, antioxidant and antibacterial activity of essential oil from lemon peel

(2017) Liang-Liang Zhang et al.   NATURAL PRODUCT RESEARCH

Chemodiversity of Nepeta menthoides Boiss. & Bohse. essential oil from Iran and antimicrobial, acetylcholinesterase inhibitory and cytotoxic properties of 1,8-cineole chemotype

(2017) Niloofar Kahkeshani et al.   NATURAL PRODUCT RESEARCH

Antiallodynic effect of β-caryophyllene on paclitaxel-induced peripheral neuropathy in mice

(2017) Gabriela C. Segat et al.   NEUROPHARMACOLOGY

Induction of chronic migraine phenotypes in a rat model after environmental irritant exposure

(2017) Phillip Edward Kunkler et al.   PAIN

Toxicity of β-citronellol, geraniol and linalool from Pelargonium roseum essential oil against the West Nile and filariasis vector Culex pipiens (Diptera: Culicidae)

(2017) Mohaddeseh Abouhosseini Tabari et al.   RESEARCH IN VETERINARY SCIENCE

Understanding migraine: Potential role of neurogenic inflammation

(2016) Rakesh Malhotra   Annals of Indian Academy of Neurology

Effects of clary sage oil and its main components, linalool and linalyl acetate, on the plasma membrane of Candida albicans: an in vivo EPR study

(2016) Ágnes Blaskó et al.   APOPTOSIS

Inhibitory effects of geranium essential oil and its major component, citronellol, on degranulation and cytokine production by mast cells

(2016) Yuko Kobayashi et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Migraine biomarkers in cerebrospinal fluid: A systematic review and meta-analysis

(2016) Robin M van Dongen et al.   CEPHALALGIA

Anti-inflammatory and antiedematogenic activity of the Ocimum basilicum essential oil and its main compound estragole: In vivo mouse models

(2016) Lindaiane Bezerra Rodrigues et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Essential Oils, Part V

(2016) Anton de Groot et al.   Dermatitis

Involvement of transient receptor potential A1 channel in algesic and analgesic actions of the organic compound limonene

(2016) T. Kaimoto et al.   EUROPEAN JOURNAL OF PAIN

Factors Influencing Response to Pharmacologic Treatment of Migraine in a Pediatric Headache Clinic

(2016) Tal Eidlitz Markus et al.   HEADACHE

Anti-inflammatory effects of royal poinciana through inhibition of toll-like receptor 4 signaling pathway

(2016) Satyajit Patra et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Efficacy and safety of enteric coated capsules of anise oil to treat irritable bowel syndrome

(2016) Maryam Mosaffa-Jahromi et al.   JOURNAL OF ETHNOPHARMACOLOGY

High-Concentration L-Menthol Exhibits Counter-Irritancy to Neurogenic Inflammation, Thermal and Mechanical Hyperalgesia Caused by Trans-cinnamaldehyde

(2016) Hjalte H. Andersen et al.   JOURNAL OF PAIN

β-Caryophyllene, a phytocannabinoid attenuates oxidative stress, neuroinflammation, glial activation, and salvages dopaminergic neurons in a rat model of Parkinson disease

(2016) Shreesh Ojha et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Effects of garlic extract on spreading depression: In vitro and in vivo investigations

(2016) Claudia Marschollek et al.   NUTRITIONAL NEUROSCIENCE

Role of Cyclooxygenase-2 in Relation to Nitric Oxide and Endothelin-1 on Pathogenesis of Cerebral Vasospasm After Subarachnoid Hemorrhage in Rabbit

(2016) Akira Munakata et al.   Translational Stroke Research

Alpha-Pinene Exhibits Anti-Inflammatory Activity Through the Suppression of MAPKs and the NF-κB Pathway in Mouse Peritoneal Macrophages

(2015) Dae-Seung Kim et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

(+)-Borneol alleviates mechanical hyperalgesia in models of chronic inflammatory and neuropathic pain in mice

(2015) Jun Jiang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Drug safety and tolerability in prophylactic migraine treatment

(2015) László Vécsei et al.   Expert Opinion On Drug Safety

Elemene, the essential oil of Curcuma wenyujin, inhibits osteogenic differentiation in ankylosing spondylitis

(2015) Ying-yan Zhou et al.   JOINT BONE SPINE

Function and Postnatal Changes of Dural Afferent Fibers Expressing TRPM8 Channels

(2015) Lynn Ren et al.   Molecular Pain

Linalool Inhibits LPS-Induced Inflammation in BV2 Microglia Cells by Activating Nrf2

(2015) Yang Li et al.   NEUROCHEMICAL RESEARCH

l-Menthone confers antidepressant-like effects in an unpredictable chronic mild stress mouse model via NLRP3 inflammasome-mediated inflammatory cytokines and central neurotransmitters

(2015) Jinsong Xue et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Inhibition of melanogenesis byβ-caryophyllene from lime mint essential oil in mouse B16 melanoma cells

(2015) C.-H. Yang et al.   INTERNATIONAL JOURNAL OF COSMETIC SCIENCE

Efficacy and Tolerability of STOPAIN for a Migraine Attack

(2015) Andrea St. Cyr et al.   Frontiers in Neurology

Ligustilide inhibits microglia-mediated proinflammatory cytokines production and inflammatory pain

(2014) Ming-Di Zhu et al.   BRAIN RESEARCH BULLETIN

The synergetic effect of edaravone and borneol in the rat model of ischemic stroke

(2014) Hai-Yin Wu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Diallyl trisulfide exerts anti-inflammatory effects in lipopolysaccharide-stimulated RAW 264.7 macrophages by suppressing the Toll-like receptor 4/nuclear factor-κB pathway

(2014) HYE HYEON LEE et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Effects of the essential oil of Croton zehntneri and its major components, anethole and estragole, on the rat corpora cavernosa

(2014) Pedro Henrique Bezerra Cabral et al.   LIFE SCIENCES

Enhanced production of nitric oxide in A549 cells through activation of TRPA1 ion channel by cold stress

(2014) Wenwu Sun et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Comparative study of the anti-edematogenic effects of anethole and estragole

(2014) Edson L. Ponte et al.   Pharmacological Reports

Enhanced endothelin receptor type B-mediated vasodilation and underlying [Ca2+]iin mesenteric microvessels of pregnant rats

(2013) Marc Q Mazzuca et al.   BRITISH JOURNAL OF PHARMACOLOGY

Prostaglandins in migraine

(2013) Maria Antonova et al.   CURRENT OPINION IN NEUROLOGY

Implication of limonene and linalyl acetate in cytotoxicity induced by bergamot essential oil in human neuroblastoma cells

(2013) Rossella Russo et al.   FITOTERAPIA

Short-term heating reduces the anti-inflammatory effects of fresh raw garlic extracts on the LPS-induced production of NO and pro-inflammatory cytokines by downregulating allicin activity in RAW 264.7 macrophages

(2013) Jung-Hye Shin et al.   FOOD AND CHEMICAL TOXICOLOGY

Inhibitory effects of monoterpenes on human TRPA1 and the structural basis of their activity

(2013) Masayuki Takaishi et al.   Journal of Physiological Sciences

Paranasal sinus nitric oxide and migraine: A new hypothesis on the sino rhinogenic theory

(2013) Senanayake Mudiyanselage Rathnasiri Bandara   MEDICAL HYPOTHESES

Inhibitory effects and molecular mechanisms of garlic organosulfur compounds on the production of inflammatory mediators

(2013) Sixiang You et al.   MOLECULAR NUTRITION & FOOD RESEARCH

1,8-Cineole (Eucalyptol) Mitigates Inflammation in Amyloid Beta Toxicated PC12 Cells: Relevance to Alzheimer’s Disease

(2013) Andleeb Khan et al.   NEUROCHEMICAL RESEARCH

Migraine pathophysiology: Anatomy of the trigeminovascular pathway and associated neurological symptoms, cortical spreading depression, sensitization, and modulation of pain

(2013) Rodrigo Noseda et al.   PAIN

Anti-inflammatory effects of (Z)-ligustilide through suppression of mitogen-activated protein kinases and nuclear factor-κB activation pathways

(2012) Ji Won Chung et al.   ARCHIVES OF PHARMACAL RESEARCH

5-Lipoxygenase Inhibition of the Fructus of Foeniculum vulgare and Its Constituents

(2012) Je-Hyeong Lee et al.   Biomolecules & Therapeutics

Direct Interactions between Calcitonin-Like Receptor (CLR) and CGRP-Receptor Component Protein (RCP) Regulate CGRP Receptor Signaling

(2012) Sophie C. Egea et al.   ENDOCRINOLOGY

Lavender Essential Oil in the Treatment of Migraine Headache: A Placebo-Controlled Clinical Trial

(2012) Payam Sasannejad et al.   EUROPEAN NEUROLOGY

Migraine: Possible Role of Shear-Induced Platelet Aggregation With Serotonin Release

(2012) Piet Borgdorff et al.   HEADACHE

Analysis of the chemical composition, acute toxicity and skin sensitivity of essential oil from rhizomes of Ligusticum chuanxiong

(2012) Hong Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

1,8-Cineole, a TRPM8 Agonist, is a Novel Natural Antagonist of Human TRPA1

(2012) Masayuki Takaishi et al.   Molecular Pain

Cutaneous allodynia in patients with episodic migraine

(2012) Hayat Güven et al.   NEUROLOGICAL SCIENCES

Antimicrobial activity of a traditionally used complex essential oil distillate (Olbas® Tropfen) in comparison to its individual essential oil ingredients

(2012) Razan Hamoud et al.   PHYTOMEDICINE

Inhibitory effects of diallyl disulfide on the production of inflammatory mediators and cytokines in lipopolysaccharide-activated BV2 microglia

(2012) Hye Young Park et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Ligustilide prevents LPS-induced iNOS expression in RAW 264.7 macrophages by preventing ROS production and down-regulating the MAPK, NF-κB and AP-1 signaling pathways

(2011) Yu-Wen Su et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Amelioration of Experimental Autoimmune Encephalomyelitis by β-elemene Treatment is Associated with Th17 and Treg Cell Balance

(2011) Rongwei Zhang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Limonene Suppresses Lipopolysaccharide-Induced Production of Nitric Oxide, Prostaglandin E2, and Pro-inflammatory Cytokines in RAW 264.7 Macrophages

(2011) Weon-Jong Yoon et al.   Journal of Oleo Science

The role of serotonin receptors in migraine headaches

(2011) A. Y. Sokolov et al.   Neurochemical Journal

Z-ligustilide attenuates lipopolysaccharide-induced proinflammatory response via inhibiting NF-κB pathway in primary rat microglia

(2010) Jing Wang et al.   ACTA PHARMACOLOGICA SINICA

Hypotensive and Vasorelaxant Effects of Citronellol, a Monoterpene Alcohol, in Rats

(2010) Joana F. A. Bastos et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cutaneous application of menthol 10% solution as an abortive treatment of migraine without aura: a randomised, double-blind, placebo-controlled, crossed-over study

(2010) A. Borhani Haghighi et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

The Antinociceptive Effect of (-)-Linalool in Models of Chronic Inflammatory and Neuropathic Hypersensitivity in Mice

(2010) Patricia Aparecida Batista et al.   JOURNAL OF PAIN

Protection by borneol on cortical neurons against oxygen-glucose deprivation/reperfusion: involvement of anti-oxidation and anti-inflammation through nuclear transcription factor κappaB signaling pathway

(2010) R. Liu et al.   NEUROSCIENCE

Inhibitory Effects of Citronellol and Geraniol on Nitric Oxide and Prostaglandin E2Production in Macrophages

(2010) Yu-Wen Su et al.   PLANTA MEDICA

Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity

(2009) Alban Latremoliere et al.   JOURNAL OF PAIN

Pharmacodynamic action and mechanism of volatile oil from Rhizoma Ligustici Chuanxiong Hort. on treating headache

(2009) Cheng Peng et al.   PHYTOMEDICINE

Endothelium-dependent vasorelaxant effects of the essential oil from aerial parts of Alpinia zerumbet and its main constituent 1,8-cineole in rats

(2009) Nilson V. Pinto et al.   PHYTOMEDICINE

Evidence for the involvement of ionotropic glutamatergic receptors on the antinociceptive effect of (−)-linalool in mice

(2008) Patrícia Aparecida Batista et al.   NEUROSCIENCE LETTERS

The role of nitric oxide (NO) in migraine, tension-type headache and cluster headache

(2008) J OLESEN   PHARMACOLOGY & THERAPEUTICS

The discovery of nitric oxide and its role in vascular biology

(2006) S Moncada et al.   BRITISH JOURNAL OF PHARMACOLOGY