Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy

Circ‐ IGF1R inhibits cell invasion and migration in non‐small cell lung cancer

(2020) Zhanyu Xu et al.   Thoracic Cancer

CircHivep2 contributes to microglia activation and inflammation via miR‐181a‐5p/SOCS2 signalling in mice with kainic acid‐induced epileptic seizures

(2020) Gao Xiaoying et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration

(2019) Haiqiong Wang et al.   Science Advances

Circular HDAC9/microRNA-138/Sirtuin-1 Pathway Mediates Synaptic and Amyloid Precursor Protein Processing Deficits in Alzheimer’s Disease

(2019) Yanjun Lu et al.   Neuroscience Bulletin

Epilepsy in adults

(2019) Roland D Thijs et al.   LANCET

Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway

(2019) Abubakar Wani et al.   Autophagy

The 4-Aminopyridine Model of Acute Seizures in vitro Elucidates Efficacy of New Antiepileptic Drugs

(2019) Hanno Heuzeroth et al.   Frontiers in Neuroscience

Circular RNA circDLGAP4 exerts neuroprotective effects via modulating miR-134-5p/CREB pathway in Parkinson’s disease

(2019) Zhong Feng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Circ-IGF1R has pro-proliferative and anti-apoptotic effects in HCC by activating the PI3K/AKT pathway

(2019) Hang-wei Fu et al.   GENE

An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

(2019) Umber Dube et al.   NATURE NEUROSCIENCE

Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke

(2018) Bing Han et al.   Autophagy

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

(2018) Seung Pil Yun et al.   NATURE MEDICINE

MFG-E8 reverses microglial-induced neurotoxic astrocyte (A1) via NF-κB and PI3K-Akt pathways

(2018) Xiaotian Xu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inhibition of MyD88 Signaling Skews Microglia/Macrophage Polarization and Attenuates Neuronal Apoptosis in the Hippocampus After Status Epilepticus in Mice

(2018) Jin-Tao Liu et al.   Neurotherapeutics

A Critical Role of Autophagy in Regulating Microglia Polarization in Neurodegeneration

(2018) Meng-meng Jin et al.   Frontiers in Aging Neuroscience

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia via P2Y 1 Receptor Downregulation

(2017) Youichi Shinozaki et al.   Cell Reports

Pathophysiology and Clinical Utility of Non-coding RNAs in Epilepsy

(2017) Yiye Shao et al.   Frontiers in Molecular Neuroscience

Neuronal Injury, Gliosis, and Glial Proliferation in Two Models of Temporal Lobe Epilepsy

(2016) Jaycie L. Loewen et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Advances in the development of biomarkers for epilepsy

(2016) Asla Pitkänen et al.   LANCET NEUROLOGY

Calpain-dependent truncated form of TrkB-FL increases in neurodegenerative processes

(2016) Víctor Danelon et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Role of the Akt/GSK-3β/CRMP-2 pathway in axon degeneration of dopaminergic neurons resulting from MPP+ toxicity

(2015) Wei Fang et al.   BRAIN RESEARCH

Microglial M1/M2 polarization and metabolic states

(2015) Ruben Orihuela et al.   BRITISH JOURNAL OF PHARMACOLOGY

Insulin growth factor-1 (IGF-1) enhances hippocampal excitatory and seizure activity through IGF-1 receptor-mediated mechanisms in the epileptic brain

(2015) G. Jiang et al.   CLINICAL SCIENCE

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

(2015) Agnieszka Rybak-Wolf et al.   MOLECULAR CELL

Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity

(2015) Xintian You et al.   NATURE NEUROSCIENCE

Detecting and characterizing circular RNAs

(2014) William R Jeck et al.   NATURE BIOTECHNOLOGY

Circular RNAs: diversity of form and function

(2014) Erika Lasda et al.   RNA

Diverse cellular and molecular modes of axon degeneration

(2014) Lukas J. Neukomm et al.   TRENDS IN CELL BIOLOGY

Cell-Type Specific Features of Circular RNA Expression

(2013) Julia Salzman et al.   PLoS Genetics

Axonal degeneration as a therapeutic target in the CNS

(2012) Paul Lingor et al.   CELL AND TISSUE RESEARCH

Finding a better drug for epilepsy: Antiepileptogenesis targets

(2012) Katja Kobow et al.   EPILEPSIA

Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor

(2012) Joana C d’Avila et al.   Journal of Neuroinflammation

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Inflammation in epilepsy: Clinical observations

(2011) Eleonora Aronica et al.   EPILEPSIA

Aquaporin-4 Reduces Post-Traumatic Seizure Susceptibility by Promoting Astrocytic Glial Scar Formation in Mice

(2011) Daniel C Lu et al.   JOURNAL OF NEUROTRAUMA

Rapid astrocyte and microglial activation following pilocarpine-induced seizures in rats

(2010) Lee A. Shapiro et al.   EPILEPSIA

Effects of 4-Aminopyridine on Organelle Movement in Cultured Mouse Dorsal Root Ganglion Neurites

(2009) Hiromi Hiruma et al.   JOURNAL OF MOLECULAR NEUROSCIENCE