Finding a better drug for epilepsy: Antiepileptogenesis targets

Bystander Effect on Brain Tissue of Mesoangioblasts Producing Neurotrophins

(2012) Tao Su et al.   CELL TRANSPLANTATION

The Ketogenic Diet as a Treatment Paradigm for Diverse Neurological Disorders

(2012) Carl E. Stafstrom et al.   Frontiers in Pharmacology

Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy

(2011) Shawn McClelland et al.   ANNALS OF NEUROLOGY

Erythropoietin, erythropoiesis and beyond

(2011) S. Chateauvieux et al.   BIOCHEMICAL PHARMACOLOGY

Diffusion tensor MRI with tract-based spatial statistics and histology reveals undiscovered lesioned areas in kainate model of epilepsy in rat

(2011) Alejandra Sierra et al.   Brain Structure & Function

The erythropoietin-derived peptide mimetic pHBSP affects cellular and cognitive consequences in a rat post-status epilepticus model

(2011) Natalie Seeger et al.   EPILEPSIA

The methylation hypothesis: Do epigenetic chromatin modifications play a role in epileptogenesis?

(2011) Katja Kobow et al.   EPILEPSIA

Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus

(2011) Beatrice Paradiso et al.   EPILEPSIA

The omega-3 fatty acid-derived neuroprotectin D1 limits hippocampal hyperexcitability and seizure susceptibility in kindling epileptogenesis

(2011) Alberto E. Musto et al.   EPILEPSIA

Ketogenic diet does not change NKCC1 and KCC2 expression in rat hippocampus

(2011) Gisela Gómez-Lira et al.   EPILEPSY RESEARCH

Fatty acid oxidation and epilepsy

(2011) Stéphane Auvin   EPILEPSY RESEARCH

Modulation of oxidative stress and mitochondrial function by the ketogenic diet

(2011) Julie Milder et al.   EPILEPSY RESEARCH

A ketogenic diet suppresses seizures in mice through adenosine A1 receptors

(2011) Susan A. Masino et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased Expression of DNA methyltransferase 1 and 3a in Human Temporal Lobe Epilepsy

(2011) Qiong Zhu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

A ketogenic diet reduces long-term potentiation in the dentate gyrus of freely behaving rats

(2011) Jessica L. Koranda et al.   JOURNAL OF NEUROPHYSIOLOGY

Hypoxia-Induced Neonatal Seizures Diminish Silent Synapses and Long-Term Potentiation in Hippocampal CA1 Neurons

(2011) C. Zhou et al.   JOURNAL OF NEUROSCIENCE

Mechanisms of epileptogenesis and potential treatment targets

(2011) Asla Pitkänen et al.   LANCET NEUROLOGY

Targets for preventing epilepsy following cortical injury

(2011) Huifang Li et al.   NEUROSCIENCE LETTERS

Ketogenic diet protects against epileptogenesis as well as neuronal loss in amygdaloid-kindling seizures

(2011) Yan Jiang et al.   NEUROSCIENCE LETTERS

Oral Administration of Docosahexaenoic Acid/Eicosapentaeinoic Acids Is Not Anticonvulsant in Rats: Implications for Translational Research

(2011) Niccolo Curatolo et al.   PEDIATRIC RESEARCH

Is It Safe to Use a Diuretic to Treat Seizures Early in Development ?

(2011) Y. Ben-Ari et al.   Epilepsy Currents

Altered GABA Signaling in Early Life Epilepsies

(2011) Stephen W. Briggs et al.   NEURAL PLASTICITY

Blocking Early GABA Depolarization with Bumetanide Results in Permanent Alterations in Cortical Circuits and Sensorimotor Gating Deficits

(2010) Doris D. Wang et al.   CEREBRAL CORTEX

A ketogenic diet does not impair rat behavior or long-term potentiation

(2010) Liu Lin Thio et al.   EPILEPSIA

Ketogenic diet exhibits neuroprotective effects in hippocampus but fails to prevent epileptogenesis in the lithium-pilocarpine model of mesial temporal lobe epilepsy in adult rats

(2010) Benjamin Linard et al.   EPILEPSIA

Polyunsaturated fatty acids and epilepsy

(2010) Ameer Y. Taha et al.   EPILEPSIA

Does ketogenic diet alter seizure sensitivity and cell loss following fluid percussion injury?

(2010) Philip A. Schwartzkroin et al.   EPILEPSY RESEARCH

Hippocampal FGF-2 and BDNF overexpression attenuates epileptogenesis-associated neuroinflammation and reduces spontaneous recurrent seizures

(2010) Roberta Bovolenta et al.   Journal of Neuroinflammation

Disease-Modifying Effects of Phenobarbital and the NKCC1 Inhibitor Bumetanide in the Pilocarpine Model of Temporal Lobe Epilepsy

(2010) C. Brandt et al.   JOURNAL OF NEUROSCIENCE

The Developmental Stage of Dentate Granule Cells Dictates Their Contribution to Seizure-Induced Plasticity

(2010) M. M. Kron et al.   JOURNAL OF NEUROSCIENCE

Brain function and chromatin plasticity

(2010) Catherine Dulac   NATURE

Epigenetic mechanisms underlying human epileptic disorders and the process of epileptogenesis

(2010) Irfan A. Qureshi et al.   NEUROBIOLOGY OF DISEASE

Diffusion tensor MRI of axonal plasticity in the rat hippocampus

(2010) Teemu Laitinen et al.   NEUROIMAGE

Prevention or Modification of Epileptogenesis after Brain Insults: Experimental Approaches and Translational Research

(2010) W. Loscher et al.   PHARMACOLOGICAL REVIEWS

Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice

(2010) S. Peleg et al.   SCIENCE

Anticonvulsant and antiepileptic actions of 2-deoxy-D-glucose in epilepsy models

(2009) Carl E. Stafstrom et al.   ANNALS OF NEUROLOGY

Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

(2009) Çagla Eroglu et al.   CELL

Epilepsy following cortical injury: Cellular and molecular mechanisms as targets for potential prophylaxis

(2009) David A. Prince et al.   EPILEPSIA

Postnatal neurogenesis as a therapeutic target in temporal lobe epilepsy

(2009) Helen E. Scharfman et al.   EPILEPSY RESEARCH

Increased Reelin Promoter Methylation Is Associated With Granule Cell Dispersion in Human Temporal Lobe Epilepsy

(2009) Katja Kobow et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies

(2009) Rocio G Urdinguio et al.   LANCET NEUROLOGY

Ketogenic diet does not disturb neurogenesis in the dentate gyrus in rats

(2009) Joakim Strandberg et al.   NEUROREPORT

Localized delivery of fibroblast growth factor-2 and brain-derived neurotrophic factor reduces spontaneous seizures in an epilepsy model

(2009) B. Paradiso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetics and the nervous system

(2008) Mark F. Mehler   ANNALS OF NEUROLOGY

The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies

(2008) Marwan Maalouf et al.   BRAIN RESEARCH REVIEWS

Neurogenesis in the human hippocampus and its relevance to temporal lobe epilepsies

(2008) Florian A. Siebzehnrubl et al.   EPILEPSIA

Effects of the ketogenic diet on neurogenesis after kainic acid-induced seizures in mice

(2008) Young Se Kwon et al.   EPILEPSY RESEARCH

Early Alterations of AMPA Receptors Mediate Synaptic Potentiation Induced by Neonatal Seizures

(2008) S. N. Rakhade et al.   JOURNAL OF NEUROSCIENCE

Synaptic integration and plasticity of new neurons in the adult hippocampus

(2008) Shaoyu Ge et al.   JOURNAL OF PHYSIOLOGY-LONDON

Nonrandom connectivity of the epileptic dentate gyrus predicts a major role for neuronal hubs in seizures

(2008) R. J. Morgan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles of the cation–chloride cotransporters in neurological disease

(2008) Kristopher T Kahle et al.   Nature clinical practice. Neurology

Bumetanide enhances phenobarbital efficacy in a neonatal seizure model

(2007) Volodymyr I. Dzhala et al.   ANNALS OF NEUROLOGY

Progress in neuroprotective strategies for preventing epilepsy

(2007) M ACHARYA et al.   PROGRESS IN NEUROBIOLOGY