Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke

Transcriptomic analysis reveals differential activation of microglial genes after ischemic stroke in mice

(2017) Akbar Khan et al.   NEUROSCIENCE

Mir143-BBC3 cascade reduces microglial survival via interplay between apoptosis and autophagy: Implications for methamphetamine-mediated neurotoxicity

(2016) Yuan Zhang et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Circular RNA expression alterations are involved in OGD/R-induced neuron injury

(2016) Shao-Peng Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ADAMTS13-mediated thrombolysis of t-PA-resistant occlusions in ischemic stroke in mice

(2016) F. Denorme et al.   BLOOD

Hsa_circ_0001649: A circular RNA and potential novel biomarker for hepatocellular carcinoma

(2016) Meilin Qin et al.   Cancer Biomarkers

A circular RNA protects the heart from pathological hypertrophy and heart failure by targeting miR-223

(2016) Kun Wang et al.   EUROPEAN HEART JOURNAL

Potential role of microRNA-7 in the anti-neuroinflammation effects of nicorandil in astrocytes induced by oxygen-glucose deprivation

(2016) Yin-Feng Dong et al.   Journal of Neuroinflammation

Constitutive aryl hydrocarbon receptor signaling constrains type I interferon–mediated antiviral innate defense

(2016) Taisho Yamada et al.   NATURE IMMUNOLOGY

Stroke and t-PA — Triggering New Paradigms of Care

(2016) Stephanie J. Snow   NEW ENGLAND JOURNAL OF MEDICINE

Astrocyte-derived interleukin-15 exacerbates ischemic brain injury via propagation of cellular immunity

(2016) Minshu Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke

(2016) Zhongwu Liu et al.   PROGRESS IN NEUROBIOLOGY

Astrocytes: Key Regulators of Neuroinflammation

(2016) Emanuela Colombo et al.   TRENDS IN IMMUNOLOGY

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

(2016) Qiupeng Zheng et al.   Nature Communications

Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury

(2016) Yejie Shi et al.   Nature Communications

Silencing microRNA-143 protects the integrity of the blood-brain barrier: implications for methamphetamine abuse

(2016) Ying Bai et al.   Scientific Reports

Identification and Characterization of Hypoxia-Regulated Endothelial Circular RNANovelty and Significance

(2015) Jes-Niels Boeckel et al.   CIRCULATION RESEARCH

Circular RNAs in Eukaryotic Cells

(2015) Liang Chen et al.   CURRENT GENOMICS

Loss of the Mono-ADP-ribosyltransferase, Tiparp, Increases Sensitivity to Dioxin-induced Steatohepatitis and Lethality

(2015) Shaimaa Ahmed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The bimodally expressed microRNA miR-142 gates exit from pluripotency

(2015) H. L. Sladitschek et al.   Molecular Systems Biology

MicroRNA-142-3p inhibits cell proliferation and invasion of cervical cancer cells by targeting FZD7

(2015) Boya Deng et al.   TUMOR BIOLOGY

Role of P38 MAPK on MMP Activity in Photothrombotic Stroke Mice as Measured using an Ultrafast MMP Activatable Probe

(2015) Di Chang et al.   Scientific Reports

Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways

(2014) Ya-Dan Wen et al.   Autophagy

Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury

(2014) Xiangnan Zhang et al.   Autophagy

A combination of four active compounds alleviates cerebral ischemia-reperfusion injury in correlation with inhibition of autophagy and modulation of AMPK/mTOR and JNK pathways

(2014) Zhongshun Guo et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Detecting and characterizing circular RNAs

(2014) William R Jeck et al.   NATURE BIOTECHNOLOGY

Autophagy Activation Contributes to the Neuroprotection of Remote Ischemic Perconditioning Against Focal Cerebral Ischemia in Rats

(2014) Jingyuan Su et al.   NEUROCHEMICAL RESEARCH

Stepwise Recruitment of Transcellular and Paracellular Pathways Underlies Blood-Brain Barrier Breakdown in Stroke

(2014) Daniel Knowland et al.   NEURON

Family-wide analysis of poly(ADP-ribose) polymerase activity

(2014) Sejal Vyas et al.   Nature Communications

MiR-9 promotes microglial activation by targeting MCPIP1

(2014) Honghong Yao et al.   Nature Communications

Image-guided Pro-angiogenic Therapy in Diabetic Stroke Mouse Models Using a Multi-modal Nanoprobe

(2014) Ying-Ying Bai et al.   Theranostics

Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance

(2013) Xiangnan Zhang et al.   Autophagy

Noncanonical Autophagy Promotes the Visual Cycle

(2013) Ji-Young Kim et al.   CELL

miR-142-3p Controls the Specification of Definitive Hemangioblasts during Ontogeny

(2013) Rachael Nimmo et al.   DEVELOPMENTAL CELL

Up-regulation of microRNA-142 in simian immunodeficiency virus encephalitis leads to repression of sirtuin1

(2013) Amrita Datta Chaudhuri et al.   FASEB JOURNAL

Serum miR-142-3p is associated with early relapse in operable lung adenocarcinoma patients

(2013) Sajo Kaduthanam et al.   LUNG CANCER

The Glucocorticoid Receptor and KLF15 Regulate Gene Expression Dynamics and Integrate Signals through Feed-Forward Circuitry

(2013) S. K. Sasse et al.   MOLECULAR AND CELLULAR BIOLOGY

PARP-1 and gene regulation: Progress and puzzles

(2013) W. Lee Kraus et al.   MOLECULAR ASPECTS OF MEDICINE

Epigenetic Regulation of the miR142-3p/Interleukin-6 Circuit in Glioblastoma

(2013) Guang-Yuh Chiou et al.   MOLECULAR CELL

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction

(2012) Shihui Xing et al.   Autophagy

Direct protection of neurons and astrocytes by matrine via inhibition of the NF-κB signaling pathway contributes to neuroprotection against focal cerebral ischemia

(2012) Min Xu et al.   BRAIN RESEARCH

Deletion of the ageing gene p66Shc reduces early stroke size following ischaemia/reperfusion brain injury

(2012) Remo D. Spescha et al.   EUROPEAN HEART JOURNAL

Upregulation of miR-142-3p in Peripheral Blood Mononuclear Cells of Operationally Tolerant Patients with a Renal Transplant

(2012) R. Danger et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

New PARP Gene with an Anti-Alphavirus Function

(2012) S. Atasheva et al.   JOURNAL OF VIROLOGY

NAD+ administration decreases ischemic brain damage partially by blocking autophagy in a mouse model of brain ischemia

(2012) Chaobo Zheng et al.   NEUROSCIENCE LETTERS

Inhibition of Autophagy Contributes to Ischemic Postconditioning-Induced Neuroprotection against Focal Cerebral Ischemia in Rats

(2012) Li Gao et al.   PLoS One

Autophagy activation is involved in neuroprotection induced by hyperbaric oxygen preconditioning against focal cerebral ischemia in rats

(2011) Wenjun Yan et al.   BRAIN RESEARCH

MiR-142-3p as a potential prognostic biomarker for esophageal squamous cell carcinoma

(2011) Rui-Jun Lin et al.   JOURNAL OF SURGICAL ONCOLOGY

Autophagy was activated in injured astrocytes and mildly decreased cell survival following glucose and oxygen deprivation and focal cerebral ischemia

(2010) Ai-Ping Qin et al.   Autophagy

Autophagy activation is associated with neuroprotection in a rat model of focal cerebral ischemic preconditioning

(2010) Rui Sheng et al.   Autophagy

Cocaine-mediated induction of platelet-derived growth factor: implication for increased vascular permeability

(2010) H. Yao et al.   BLOOD

Treatment of cerebral ischemia by disrupting ischemia-induced interaction of nNOS with PSD-95

(2010) Li Zhou et al.   NATURE MEDICINE

Toward a unified nomenclature for mammalian ADP-ribosyltransferases

(2010) Michael O. Hottiger et al.   TRENDS IN BIOCHEMICAL SCIENCES

In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance

(2009) A. Annoni et al.   BLOOD

Rat focal cerebral ischemia induced astrocyte proliferation and delayed neuronal death are attenuated by cyclin-dependent kinase inhibition

(2008) Wei Wang et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Neuroprotection Does Not Work!

(2008) Joachim Röther   STROKE