Using digital technologies in clinical trials: Current and future applications

Virtual Clinical Trials: Perspectives in Dermatology

(2020) Zarqa Ali et al.   DERMATOLOGY

Big data in digital healthcare: lessons learnt and recommendations for general practice

(2020) Raag Agrawal et al.   HEREDITY

Effect of a Machine Learning–Derived Early Warning System for Intraoperative Hypotension vs Standard Care on Depth and Duration of Intraoperative Hypotension During Elective Noncardiac Surgery

(2020) Marije Wijnberge et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Ethical dilemmas posed by mobile health and machine learning in psychiatry research

(2020) Nicholas C Jacobson et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Covid-19 and Health Care’s Digital Revolution

(2020) Sirina Keesara et al.   NEW ENGLAND JOURNAL OF MEDICINE

Using digital tools in the recruitment and retention in randomised controlled trials: survey of UK Clinical Trial Units and a qualitative study

(2020) Amanda Blatch-Jones et al.   Trials

Digital tools for the recruitment and retention of participants in randomised controlled trials: a systematic map

(2020) Geoff K. Frampton et al.   Trials

Choosing a Mobile Sensor Technology for a Clinical Trial: Statistical Considerations, Developments and Learnings

(2020) Colleen Russell et al.   Therapeutic Innovation & Regulatory Science

Rapid Transition of Individual and Group-based Behavioral Outpatient Visits to Telepsychiatry in Response to COVID-19

(2020) Erin L. Winstanley et al.   Journal of Addiction Medicine

Data sharing practices of medicines related apps and the mobile ecosystem: traffic, content, and network analysis

(2019) Quinn Grundy et al.   BMJ-British Medical Journal

Prototype of running clinical trials in an untrustworthy environment using blockchain

(2019) Daniel R. Wong et al.   Nature Communications

Real‐World Data for Regulatory Decision Making: Challenges and Possible Solutions for Europe

(2019) Alison Cave et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Barriers and Opportunities for Use of Patient Registries in Medicines Regulation

(2019) Carla Alonso Olmo et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Administrative claims data to support pragmatic clinical trial outcome ascertainment on cardiovascular health

(2019) Qinli Ma et al.   Clinical Trials

Electronic informed consent: the need to redesign the consent process for the digital age

(2019) Helen Lunt et al.   INTERNAL MEDICINE JOURNAL

The “All of Us” Research Program

(2019)   NEW ENGLAND JOURNAL OF MEDICINE

Passive Sensing of Health Outcomes Through Smartphones: Systematic Review of Current Solutions and Possible Limitations

(2019) Alina Trifan et al.   JMIR mHealth and uHealth

Does time matter? WhatsApp vs electronic mail for dental education. A pilot study

(2019) Paulina Poblete et al.   European Journal of Dental Education

Large-Scale Assessment of a Smartwatch to Identify Atrial Fibrillation

(2019) Marco V. Perez et al.   NEW ENGLAND JOURNAL OF MEDICINE

To tweet or not to tweet, that is the question: A randomized trial of Twitter effects in medical education

(2019) Lauren A. Maggio et al.   PLoS One

Blockchain’s potential to improve clinical trials—an essay by Leeza Osipenko

(2019) Leeza Osipenko   BMJ-British Medical Journal

Right Dose Right Now: bedside data-driven personalized antibiotic dosing in severe sepsis and septic shock — rationale and design of a multicenter randomized controlled superiority trial

(2019) Luca F. Roggeveen et al.   Trials

Re-inventing the randomized controlled trial in medical oncology: The registry-based trial

(2018) Siavash Foroughi et al.   Asia-Pacific Journal of Clinical Oncology

Increasing the use of mobile technology–derived endpoints in clinical trials

(2018) William G Herrington et al.   Clinical Trials

Systematic review of smartphone-based passive sensing for health and wellbeing

(2018) Victor P. Cornet et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Perspectives on Electronic Informed Consent From Patients Underrepresented in Research in the United States: A Focus Group Study

(2018) Christian M. Simon et al.   Journal of Empirical Research on Human Research Ethics

The Promise of Technology-Based Services for Addiction Treatment Clients Residing in Nonurban Areas

(2018) Erin L. Winstanley et al.   Journal of Studies on Alcohol and Drugs

TEMPORARY REMOVAL: Article Coming Soon

(2018)   AMERICAN HEART JOURNAL

Participant Recruitment and Retention in Remote eHealth Intervention Trials: Methods and Lessons Learned From a Large Randomized Controlled Trial of Two Web-Based Smoking Interventions

(2018) Noreen L Watson et al.   JOURNAL OF MEDICAL INTERNET RESEARCH

Social media and clinical trials: The pros and cons gain context when the patient is at the center

(2018) Michael A. Thompson et al.   CANCER

Reflections on the Clinical Research Enterprise: Past, Present and Future

(2018) Robert Califf et al.   CIRCULATION

Artificial intelligence in drug development: present status and future prospects

(2018) Kit-Kay Mak et al.   DRUG DISCOVERY TODAY

Recruiting for a pragmatic trial using the electronic health record and patient portal: successes and lessons learned

(2018) Emily Pfaff et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Bridging the gap between the randomised clinical trial world and the real world by combination of population-based registry and electronic health record data: A case study in haemato-oncology

(2017) R.E. Kibbelaar et al.   EUROPEAN JOURNAL OF CANCER

eSource for clinical trials: Implementation and evaluation of a standards-based approach in a real world trial

(2017) Jean-Francois Ethier et al.   INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS

Efficient design of clinical trials and epidemiological research: is it possible?

(2017) Michael S. Lauer et al.   Nature Reviews Cardiology

Blockchain technology for improving clinical research quality

(2017) Mehdi Benchoufi et al.   Trials

Consent Processes for Mobile App Mediated Research: Systematic Review

(2017) Sarah Moore et al.   JMIR mHealth and uHealth

Formative Evaluation of Participant Experience With Mobile eConsent in the App-Mediated Parkinson mPower Study: A Mixed Methods Study

(2017) Megan Doerr et al.   JMIR mHealth and uHealth

Electronic health records to facilitate clinical research

(2016) Martin R. Cowie et al.   Clinical Research in Cardiology

Mobile technology and the digitization of healthcare

(2016) Sanjeev P. Bhavnani et al.   EUROPEAN HEART JOURNAL

Registry-based randomized controlled trials- what are the advantages, challenges, and areas for future research?

(2016) Guowei Li et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Million Veteran Program: A mega-biobank to study genetic influences on health and disease

(2016) John Michael Gaziano et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Reimagining Human Research Protections for 21st Century Science

(2016) Cinnamon Bloss et al.   JOURNAL OF MEDICAL INTERNET RESEARCH

Evaluating mobile phone applications for health behaviour change: A systematic review

(2016) Fiona H McKay et al.   JOURNAL OF TELEMEDICINE AND TELECARE

Factors associated with patterns of mobile technology use among persons who inject drugs

(2016) Kelly M. Collins et al.   Substance Abuse

The ADAPTABLE Trial and Aspirin Dosing in Secondary Prevention for Patients with Coronary Artery Disease

(2016) Abigail Johnston et al.   Current Cardiology Reports

The mPower study, Parkinson disease mobile data collected using ResearchKit

(2016) Brian M. Bot et al.   Scientific Data

Using e-technologies in clinical trials

(2015) Carmen Rosa et al.   Contemporary Clinical Trials

Registry-based randomized clinical trials—a new clinical trial paradigm

(2015) Stefan James et al.   Nature Reviews Cardiology

FDA okays IT-powered trial

(2013) Laura DeFrancesco   NATURE BIOTECHNOLOGY