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Title
Aging in COVID-19: Vulnerability, immunity and intervention
Authors
Keywords
Aging, COVID-19, SARS-CoV-2, Cytokine storm, Immunopathology, Immunosenescence, Inflammaging, Anti-IL-6 therapy, Vaccination
Journal
AGEING RESEARCH REVIEWS
Volume 65, Issue -, Pages 101205
Publisher
Elsevier BV
Online
2020-10-31
DOI
10.1016/j.arr.2020.101205
References
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Note: Only part of the references are listed.- Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China
- (2020) Zunyou Wu et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- A pneumonia outbreak associated with a new coronavirus of probable bat origin
- (2020) Peng Zhou et al. NATURE
- Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany
- (2020) Camilla Rothe et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Novel Coronavirus from Patients with Pneumonia in China, 2019
- (2020) Na Zhu et al. NEW ENGLAND JOURNAL OF MEDICINE
- COVID-19: Zoonotic aspects
- (2020) Tauseef Ahmad et al. Travel Medicine and Infectious Disease
- Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan
- (2020) Jasper Fuk-Woo Chan et al. Emerging Microbes & Infections
- Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host–Virus Interaction, and Proposed Neurotropic Mechanisms
- (2020) Abdul Mannan Baig et al. ACS Chemical Neuroscience
- Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals
- (2020) Alba Grifoni et al. CELL
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- The Challenges of Vaccine Development against a New Virus during a Pandemic
- (2020) Michael S. Diamond et al. Cell Host & Microbe
- Is aberrant CD8+ T cell activation by hypertension associated with cardiac injury in severe cases of COVID-19?
- (2020) Chao Zhang et al. Cellular & Molecular Immunology
- Treatment With Convalescent Plasma for Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection
- (2020) Bin Zhang et al. CHEST
- Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System
- (2020) Mahmoud Gheblawi et al. CIRCULATION RESEARCH
- Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China
- (2020) Chuan Qin et al. CLINICAL INFECTIOUS DISEASES
- Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals
- (2020) Ling Ni et al. IMMUNITY
- Aberrant hyperactivation of cytotoxic T-cell as a potential determinant of COVID-19 severity
- (2020) Chang Kyung Kang et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma
- (2020) Chenguang Shen et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area
- (2020) Safiya Richardson et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Longitudinal hematologic and immunologic variations associated with the progression of COVID-19 patients in China
- (2020) Ruchong Chen et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Plasma IP-10 and MCP-3 levels are highly associated with disease severity and predict the progression of COVID-19
- (2020) Yang Yang et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Clinical and immunological features of severe and moderate coronavirus disease 2019
- (2020) Guang Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- Characteristics of Peripheral Lymphocyte Subset Alteration in COVID-19 Pneumonia
- (2020) Fan Wang et al. JOURNAL OF INFECTIOUS DISEASES
- TH17 responses in cytokine storm of COVID-19: An emerging target of JAK2 inhibitor Fedratinib
- (2020) Dandan Wu et al. JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
- Neurological manifestations associated with COVID-19: a review and a call for action
- (2020) Matilde Leonardi et al. JOURNAL OF NEUROLOGY
- Angiotensin‐converting enzyme‐2 ( ACE2 ), SARS‐CoV ‐2 and pathophysiology of coronavirus disease 2019 ( COVID ‐19)
- (2020) Arno R. Bourgonje et al. JOURNAL OF PATHOLOGY
- The case of Complement activation in COVID-19 multiorgan impact
- (2020) Marina Noris et al. KIDNEY INTERNATIONAL
- Kawasaki-like disease: emerging complication during the COVID-19 pandemic
- (2020) Russell M Viner et al. LANCET
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
- (2020) Fei Zhou et al. LANCET
- A preliminary study on serological assay for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 238 admitted hospital patients
- (2020) Lei Liu et al. MICROBES AND INFECTION
- The COVID-19 vaccine development landscape
- (2020) Tung Thanh Le et al. NATURE REVIEWS DRUG DISCOVERY
- Global Consortium Study of Neurological Dysfunction in COVID-19 (GCS-NeuroCOVID): Study Design and Rationale
- (2020) Jennifer Frontera et al. Neurocritical Care
- An Italian multicenter retrospective-prospective observational study on neurological manifestations of COVID-19 (NEUROCOVID)
- (2020) Carlo Ferrarese et al. NEUROLOGICAL SCIENCES
- Epidemiology of Covid-19 in a Long-Term Care Facility in King County, Washington
- (2020) Temet M. McMichael et al. NEW ENGLAND JOURNAL OF MEDICINE
- Presymptomatic SARS-CoV-2 Infections and Transmission in a Skilled Nursing Facility
- (2020) Melissa M. Arons et al. NEW ENGLAND JOURNAL OF MEDICINE
- Multiorgan and Renal Tropism of SARS-CoV-2
- (2020) Victor G. Puelles et al. NEW ENGLAND JOURNAL OF MEDICINE
- Effectiveness of convalescent plasma therapy in severe COVID-19 patients
- (2020) Kai Duan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cytokine release syndrome in severe COVID-19
- (2020) John B. Moore et al. SCIENCE
- Estimating the burden of SARS-CoV-2 in France
- (2020) Henrik Salje et al. SCIENCE
- Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases
- (2020) Cynthia Magro et al. Translational Research
- Consensus Summary Report for CEPI/BC March 12-13, 2020 Meeting: Assessment of Risk of Disease Enhancement with COVID-19 Vaccines
- (2020) Paul-Henri Lambert et al. VACCINE
- Can an effective SARS-CoV-2 vaccine be developed for the older population?
- (2020) Graham Pawelec et al. Immunity & Ageing
- “The ancient and the new”: is there an interaction between cytomegalovirus and SARS-CoV-2 infection?
- (2020) Paul Moss Immunity & Ageing
- Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China
- (2020) Chaomin Wu et al. JAMA Internal Medicine
- Current scenario of COVID-19 in pediatric age group and physiology of immune and thymus response
- (2020) Suriya Rehman et al. SAUDI JOURNAL OF BIOLOGICAL SCIENCES
- COVID-19 cytokine storm: the interplay between inflammation and coagulation
- (2020) Ricardo J Jose et al. Lancet Respiratory Medicine
- Severe Outcomes Among Patients with Coronavirus Disease 2019 (COVID-19) — United States, February 12–March 16, 2020
- (2020) et al. MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
- Understanding the age divide in COVID-19: why are children overwhelmingly spared?
- (2020) K. Lingappan et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Interleukin-6 blockade with sarilumab in severe COVID-19 pneumonia with systemic hyperinflammation: an open-label cohort study
- (2020) Emanuel Della-Torre et al. ANNALS OF THE RHEUMATIC DISEASES
- Type 1 interferons as a potential treatment against COVID-19
- (2020) Erwan Sallard et al. ANTIVIRAL RESEARCH
- Coagulation Abnormalities and Thrombosis in Patients Infected With SARS-CoV-2 and Other Pandemic Viruses
- (2020) Nigel Mackman et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Use of convalescent plasma in hospitalized patients with COVID-19: case series
- (2020) Livia Hegerova et al. BLOOD
- Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus
- (2020) Bette Korber et al. CELL
- Convalescent plasma treatment for SARS-CoV-2 infection: analysis of the first 436 donors in England, 22 April to 12 May 2020
- (2020) Heli Harvala et al. Eurosurveillance
- Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19)
- (2020) W. Joost Wiersinga et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The Development of COVID-19 Vaccines
- (2020) Nicole Lurie et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19
- (2020) Ling Li et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Early safety indicators of COVID-19 convalescent plasma in 5000 patients
- (2020) Michael J. Joyner et al. JOURNAL OF CLINICAL INVESTIGATION
- Clinical manifestations and evidence of neurological involvement in 2019 novel coronavirus SARS-CoV-2: a systematic review and meta-analysis
- (2020) Lei Wang et al. JOURNAL OF NEUROLOGY
- Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind, placebo-controlled, phase 2 trial
- (2020) Feng-Cai Zhu et al. LANCET
- Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
- (2020) Pedro M Folegatti et al. LANCET
- Comparing SARS-CoV-2 with SARS-CoV and influenza pandemics
- (2020) Eskild Petersen et al. LANCET INFECTIOUS DISEASES
- A perspective on potential antibody-dependent enhancement of SARS-CoV-2
- (2020) Ann M. Arvin et al. NATURE
- Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications
- (2020) Divij Mathew et al. SCIENCE
- Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans
- (2020) Jose Mateus et al. SCIENCE
- Age-related decline of de novo T cell responsiveness as a cause of COVID-19 severity
- (2020) Francesco Nicoli et al. GeroScience
- Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome
- (2020) Daniela Weiskopf et al. Science Immunology
- Immune Phenotyping Based on the Neutrophil-to-Lymphocyte Ratio and IgG Level Predicts Disease Severity and Outcome for Patients With COVID-19
- (2020) Bicheng Zhang et al. Frontiers in Molecular Biosciences
- Temperature, Humidity, and Latitude Analysis to Estimate Potential Spread and Seasonality of Coronavirus Disease 2019 (COVID-19)
- (2020) Mohammad M. Sajadi et al. JAMA Network Open
- Applications of machine learning and artificial intelligence for Covid-19 (SARS-CoV-2) pandemic: A review
- (2020) Samuel Lalmuanawma et al. CHAOS SOLITONS & FRACTALS
- Deep-COVID: Predicting COVID-19 from chest X-ray images using deep transfer learning
- (2020) Shervin Minaee et al. MEDICAL IMAGE ANALYSIS
- COVID-19 pandemic: Insights into structure, function, and hACE2 receptor recognition by SARS-CoV-2
- (2020) Anshumali Mittal et al. PLoS Pathogens
- Chronic Low-grade Inflammatory Phenotype (CLIP) and Senescent Immune Dysregulation
- (2019) Yiyin Chen et al. CLINICAL THERAPEUTICS
- Targeting Interleukin-6 Signaling in Clinic
- (2019) Sujin Kang et al. IMMUNITY
- 10 years of health-care reform in China: progress and gaps in Universal Health Coverage
- (2019) Winnie Yip et al. LANCET
- Age and immunity: What is “immunosenescence”?
- (2018) Graham Pawelec EXPERIMENTAL GERONTOLOGY
- The Aging Tsunami and Senior Healthcare Development in China
- (2018) Xin Li et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Influenza Virus: Dealing with a Drifting and Shifting Pathogen
- (2018) Hyunsuh Kim et al. VIRAL IMMUNOLOGY
- Origin and evolution of pathogenic coronaviruses
- (2018) Jie Cui et al. NATURE REVIEWS MICROBIOLOGY
- The Pathway to a Universal Influenza Vaccine
- (2017) Catharine I. Paules et al. IMMUNITY
- Inflammaging and ‘Garb-aging’
- (2017) Claudio Franceschi et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells
- (2016) Sylvia Heink et al. NATURE IMMUNOLOGY
- Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis
- (2016) Aartjan J. W. te Velthuis et al. NATURE REVIEWS MICROBIOLOGY
- SARS and MERS: recent insights into emerging coronaviruses
- (2016) Emmie de Wit et al. NATURE REVIEWS MICROBIOLOGY
- Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses
- (2016) Shuo Su et al. TRENDS IN MICROBIOLOGY
- Memory T cell responses targeting the SARS coronavirus persist up to 11 years post-infection
- (2016) Oi-Wing Ng et al. VACCINE
- Enhanced Viral Replication by Cellular Replicative Senescence
- (2016) Ji-Ae Kim et al. Immune Network
- A research agenda for aging in China in the 21st century
- (2015) Evandro Fei Fang et al. AGEING RESEARCH REVIEWS
- Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases
- (2014) C. Franceschi et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
- (2012) Ali M. Zaki et al. NEW ENGLAND JOURNAL OF MEDICINE
- Type 1 Interferons and Antiviral CD8 T-Cell Responses
- (2012) Raymond M. Welsh et al. PLoS Pathogens
- Engineering T Cells Specific for a Dominant Severe Acute Respiratory Syndrome Coronavirus CD8 T Cell Epitope
- (2011) H.-L. J. Oh et al. JOURNAL OF VIROLOGY
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