Could Mesenchymal Stem Cell-Derived Exosomes Be a Therapeutic Option for Critically Ill COVID-19 Patients?
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Title
Could Mesenchymal Stem Cell-Derived Exosomes Be a Therapeutic Option for Critically Ill COVID-19 Patients?
Authors
Keywords
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Journal
Journal of Clinical Medicine
Volume 9, Issue 9, Pages 2762
Publisher
MDPI AG
Online
2020-08-26
DOI
10.3390/jcm9092762
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Note: Only part of the references are listed.- Mitochondrial transfer from MSCs to T cells induces Treg differentiation and restricts inflammatory response
- (2020) Angela C Court et al. EMBO REPORTS
- Hyperbaric Oxygen Therapy Improves the Osteogenic and Vasculogenic Properties of Mesenchymal Stem Cells in the Presence of Inflammation In Vitro
- (2020) Chiara Gardin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China
- (2020) Zunyou Wu et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China
- (2020) Dawei Wang et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- On the use of corticosteroids for 2019-nCoV pneumonia
- (2020) Lianhan Shang et al. LANCET
- Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury
- (2020) Clark D Russell et al. LANCET
- Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
- (2020) Nanshan Chen et al. LANCET
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- (2020) Chaolin Huang et al. LANCET
- A pneumonia outbreak associated with a new coronavirus of probable bat origin
- (2020) Peng Zhou et al. NATURE
- COVID-19 and the cardiovascular system
- (2020) Ying-Ying Zheng et al. Nature Reviews Cardiology
- Clinical Characteristics of Coronavirus Disease 2019 in China
- (2020) Wei-jie Guan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Effects of mesenchymal stromal cells on regulatory T cells: Current understanding and clinical relevance
- (2020) Neema Negi et al. STEM CELLS
- High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa
- (2020) Hao Xu et al. International Journal of Oral Science
- Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study
- (2020) Xiaobo Yang et al. Lancet Respiratory Medicine
- Pathological findings of COVID-19 associated with acute respiratory distress syndrome
- (2020) Zhe Xu et al. Lancet Respiratory Medicine
- MSC Based Therapies—New Perspectives for the Injured Lung
- (2020) Judith Behnke et al. Journal of Clinical Medicine
- Extracellular Vesicles From Notch Activated Cardiac Mesenchymal Stem Cells Promote Myocyte Proliferation and Neovasculogenesis
- (2020) Wanling Xuan et al. Frontiers in Cell and Developmental Biology
- Does comorbidity increase the risk of patients with COVID-19: evidence from meta-analysis
- (2020) Bolin Wang et al. Aging-US
- Inside the heart of COVID-19
- (2020) Rui Adão et al. CARDIOVASCULAR RESEARCH
- COVID-19 and the Heart
- (2020) Akbarshakh Akhmerov et al. CIRCULATION RESEARCH
- Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System
- (2020) Mahmoud Gheblawi et al. CIRCULATION RESEARCH
- The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China
- (2020) Wen Zhang et al. CLINICAL IMMUNOLOGY
- COVID‐19 and diabetes
- (2020) R. C. W. Ma et al. DIABETIC MEDICINE
- Coronaviruses and the cardiovascular system: acute and long-term implications
- (2020) Tian-Yuan Xiong et al. EUROPEAN HEART JOURNAL
- Current Status of Cell-Based Therapies for Respiratory Virus Infections: Applicability to COVID-19
- (2020) Maroun Khoury et al. EUROPEAN RESPIRATORY JOURNAL
- Antihypertensive treatment with ACEI/ARB of patients with COVID-19 complicated by hypertension
- (2020) Gang Li et al. HYPERTENSION RESEARCH
- Therapeutic Use of Extracellular Vesicles for Acute and Chronic Lung Disease
- (2020) Erin N. Worthington et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cardiac and arrhythmic complications in patients with COVID‐19
- (2020) Adriano Nunes Kochi et al. JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
- COVID‐19 and diabetes: Is there enough evidence?
- (2020) Marijana Tadic et al. Journal of Clinical Hypertension
- Organ-protective effect of angiotensin-converting enzyme 2 and its effect on the prognosis of COVID-19
- (2020) Hao Cheng et al. JOURNAL OF MEDICAL VIROLOGY
- High proportion of asymptomatic and presymptomatic COVID-19 infections in travelers and returning residents to Brunei
- (2020) Justin Wong et al. JOURNAL OF TRAVEL MEDICINE
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
- (2020) Fei Zhou et al. LANCET
- Albumin-impregnated bone granules modulate the interactions between mesenchymal stem cells and monocytes under in vitro inflammatory conditions
- (2020) Eitan Mijiritsky et al. Materials Science & Engineering C-Materials for Biological Applications
- Coronavirus Disease 2019 (COVID‐19) and Cardiovascular Disease: A Viewpoint on the Potential Influence of Angiotensin‐Converting Enzyme Inhibitors/Angiotensin Receptor Blockers on Onset and Severity of Severe Acute Respiratory Syndrome Coronavirus 2 Infection
- (2020) Junyi Guo et al. Journal of the American Heart Association
- Coronavirus Disease 2019 (COVID‐19): Do Angiotensin‐Converting Enzyme Inhibitors/Angiotensin Receptor Blockers Have a Biphasic Effect?
- (2020) Rami Sommerstein et al. Journal of the American Heart Association
- Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)
- (2020) Tao Guo et al. JAMA Cardiology
- Clinical remission of a critically ill COVID-19 patient treated by human umbilical cord mesenchymal stem cells
- (2020) Bing Liang et al. MEDICINE
- Treatment for emerging viruses: Convalescent plasma and COVID-19
- (2020) Bethany L. Brown et al. TRANSFUSION AND APHERESIS SCIENCE
- Metabolic Syndrome Interferes with Packaging of Proteins within Porcine Mesenchymal Stem Cell-Derived Extracellular Vesicles
- (2019) Alfonso Eirin et al. Stem Cells Translational Medicine
- Harnessing the mesenchymal stem cell secretome for regenerative urology
- (2019) Daniel Z. Sun et al. Nature Reviews Urology
- Freeze-dried and GMP-compliant pharmaceuticals containing exosomes for acellular mesenchymal stromal cell immunomodulant therapy
- (2019) Elia Bari et al. Nanomedicine
- Pathogenesis of Acute Respiratory Distress Syndrome
- (2019) Laura Huppert et al. SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE
- Metabolic Syndrome Induces Release of Smaller Extracellular Vesicles from Porcine Mesenchymal Stem Cells
- (2019) Sabena M. Conley et al. CELL TRANSPLANTATION
- Mesenchymal stem/stromal cell secretome for lung regeneration: The long way through “pharmaceuticalization” for the best formulation
- (2019) Elia Bari et al. JOURNAL OF CONTROLLED RELEASE
- Bone marrow mesenchymal stem cell‑derived exosomes protect against myocardial infarction by promoting autophagy
- (2019) Liyuan Zou et al. Experimental and Therapeutic Medicine
- Exosomes derived from adipose tissue, bone marrow, and umbilical cord blood for cardioprotection after myocardial infarction
- (2019) Huiyu Xu et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Intrinsic Immunity Shapes Viral Resistance of Stem Cells
- (2018) Xianfang Wu et al. CELL
- Notch signaling promotes angiogenesis and improves cardiac function after myocardial infarction
- (2018) Xue-liang Zhou et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The ACE2/Angiotensin-(1–7)/MAS Axis of the Renin-Angiotensin System: Focus on Angiotensin-(1–7)
- (2018) Robson Augusto Souza Santos et al. PHYSIOLOGICAL REVIEWS
- The metabolic syndrome modifies the mRNA expression profile of extracellular vesicles derived from porcine mesenchymal stem cells
- (2018) Yu Meng et al. Diabetology & Metabolic Syndrome
- A System of Cytokines Encapsulated in ExtraCellular Vesicles
- (2018) Wendy Fitzgerald et al. Scientific Reports
- Mesenchymal stem cell-derived extracellular vesicles attenuate influenza virus-induced acute lung injury in a pig model
- (2018) Mahesh Khatri et al. Stem Cell Research & Therapy
- Mesenchymal Stem Cell Microvesicles Restore Protein Permeability Across Primary Cultures of Injured Human Lung Microvascular Endothelial Cells
- (2018) Shuling Hu et al. Stem Cells Translational Medicine
- Bioprocessing of Mesenchymal Stem Cells and Their Derivatives: Toward Cell-Free Therapeutics
- (2018) Jolene Phelps et al. Stem Cells International
- Therapeutic Potential of Autologous Adipose-Derived Stem Cells for the Treatment of Liver Disease
- (2018) Chiara Gardin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pilot Production of Mesenchymal Stem/Stromal Freeze-Dried Secretome for Cell-Free Regenerative Nanomedicine: A Validated GMP-Compliant Process
- (2018) Elia Bari et al. Cells
- Swine models, genomic tools and services to enhance our understanding of human health and diseases
- (2017) Eric M Walters et al. LAB ANIMAL
- Mesenchymal Stem Cell Microvesicles Attenuate Acute Lung Injury in Mice Partly Mediated by Ang-1 mRNA
- (2017) Xiao-Dan Tang et al. STEM CELLS
- MiRNA-Sequence Indicates That Mesenchymal Stem Cells and Exosomes Have Similar Mechanism to Enhance Cardiac Repair
- (2017) Lianbo Shao et al. Biomed Research International
- Artificial Mitochondria Transfer: Current Challenges, Advances, and Future Applications
- (2017) Andrés Caicedo et al. Stem Cells International
- 8. Pharmacologic Approaches to Glycemic Treatment
- (2016) DIABETES CARE
- Mesenchymal stem cell derived secretome and extracellular vesicles for acute lung injury and other inflammatory lung diseases
- (2016) Antoine Monsel et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Exosome: A Novel Approach to Stimulate Bone Regeneration through Regulation of Osteogenesis and Angiogenesis
- (2016) Yunhao Qin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Respiratory Syncytial Virus-Infected Mesenchymal Stem Cells Regulate Immunity via Interferon Beta and Indoleamine-2,3-Dioxygenase
- (2016) Michael B. Cheung et al. PLoS One
- Past and Present ARDS Mortality Rates: A Systematic Review
- (2016) J. Maca et al. Respiratory Care
- Exosomes Derived fromAkt-Modified Human Umbilical Cord Mesenchymal Stem Cells Improve Cardiac Regeneration and Promote Angiogenesis via Activating Platelet-Derived Growth Factor D
- (2016) Jie Ma et al. Stem Cells Translational Medicine
- Therapeutic Effects of Human Mesenchymal Stem Cell–derived Microvesicles in Severe Pneumonia in Mice
- (2015) Antoine Monsel et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Angiotensin-(1-7) attenuates airway remodelling and hyperresponsiveness in a model of chronic allergic lung inflammation
- (2015) G S Magalhães et al. BRITISH JOURNAL OF PHARMACOLOGY
- Mesenchymal Stem Cell-Derived Exosomes Improve the Microenvironment of Infarcted Myocardium Contributing to Angiogenesis and Anti-Inflammation
- (2015) Xiaomei Teng et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Exosomes secreted from GATA-4 overexpressing mesenchymal stem cells serve as a reservoir of anti-apoptotic microRNAs for cardioprotection
- (2015) Bin Yu et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs
- (2015) Donald G. Phinney et al. Nature Communications
- Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Relieve Acute Myocardial Ischemic Injury
- (2015) Yuanyuan Zhao et al. Stem Cells International
- Viral infections associated with Kawasaki disease
- (2014) Luan-Yin Chang et al. JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
- Adipocyte-derived exosomal miRNAs: a novel mechanism for obesity-related disease
- (2014) Sarah C. Ferrante et al. PEDIATRIC RESEARCH
- Ischemic Preconditioning Potentiates the Protective Effect of Stem Cells through Secretion of Exosomes by Targeting Mecp2 via miR-22
- (2014) Yuliang Feng et al. PLoS One
- IFITM-Family Proteins: The Cell's First Line of Antiviral Defense
- (2014) Charles C. Bailey et al. Annual Review of Virology
- Enhanced mesenchymal stem cell survival induced by GATA-4 overexpression is partially mediated by regulation of the miR-15 family
- (2013) Bin Yu et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Myocardial ischemia-reperfusion injury: a neglected therapeutic target
- (2013) Derek J. Hausenloy et al. JOURNAL OF CLINICAL INVESTIGATION
- Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model
- (2013) Suyan Bian et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Angiotensin-(1-7) attenuates lung fibrosis by way of Mas receptor in acute lung injury
- (2013) Qiuhua Chen et al. JOURNAL OF SURGICAL RESEARCH
- Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury
- (2013) Fatih Arslan et al. Stem Cell Research
- Human Mesenchymal Stem Cell Microvesicles for Treatment ofEscherichia coliEndotoxin-Induced Acute Lung Injury in Mice
- (2013) Ying-gang Zhu et al. STEM CELLS
- Mechanisms of Obesity-Induced Inflammation and Insulin Resistance: Insights into the Emerging Role of Nutritional Strategies
- (2013) Maeve A. McArdle et al. Frontiers in Endocrinology
- Cardiac stem cell therapy to modulate inflammation upon myocardial infarction
- (2012) F. van den Akker et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Harnessing the Mesenchymal Stem Cell Secretome for the Treatment of Cardiovascular Disease
- (2012) Sudhir H. Ranganath et al. Cell Stem Cell
- Mesenchymal stem cells differentially mediate regulatory T cells and conventional effector T cells to protect fully allogeneic islet grafts in mice
- (2012) D. M. Xu et al. DIABETOLOGIA
- The acute respiratory distress syndrome
- (2012) Michael A. Matthay et al. JOURNAL OF CLINICAL INVESTIGATION
- Mitochondrial transfer from bone-marrow–derived stromal cells to pulmonary alveoli protects against acute lung injury
- (2012) Mohammad Naimul Islam et al. NATURE MEDICINE
- Mesenchymal Stem Cells: Mechanisms of Inflammation
- (2011) Nora G. Singer et al. Annual Review of Pathology-Mechanisms of Disease
- Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1
- (2011) Brian Hynes et al. EUROPEAN HEART JOURNAL
- Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA
- (2011) C. Kukat et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Angiotensin-Converting Enzyme 2/Angiogenesis-(1–7)/Mas Axis Confers Cardiopulmonary Protection against Lung Fibrosis and Pulmonary Hypertension
- (2010) Vinayak Shenoy et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
- (2010) Ruenn Chai Lai et al. Stem Cell Research
- Antibacterial Effect of Human Mesenchymal Stem Cells Is Mediated in Part from Secretion of the Antimicrobial Peptide LL-37
- (2010) Anna Krasnodembskaya et al. STEM CELLS
- Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6
- (2009) Ryang Hwa Lee et al. Cell Stem Cell
- Isolation and characterization of chicken lung mesenchymal stromal cells and their susceptibility to avian influenza virus
- (2009) Mahesh Khatri et al. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
- Mesenchymal Stem Cells Prevent the Rejection of Fully Allogenic Islet Grafts by the Immunosuppressive Activity of Matrix Metalloproteinase-2 and -9
- (2009) Y. Ding et al. DIABETES
- SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS
- (2009) G. Y. Oudit et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung
- (2009) J. W. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide
- (2008) Guangwen Ren et al. Cell Stem Cell
- Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production
- (2008) Krisztián Németh et al. NATURE MEDICINE
- VE-Cadherin
- (2007) Dietmar Vestweber ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
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