Consequences of Metabolic Interactions during Staphylococcus aureus Infection

Monocyte metabolic reprogramming promotes pro-inflammatory activity and Staphylococcus aureus biofilm clearance

(2020) Kelsey J. Yamada et al.   PLoS Pathogens

Author Correction: Reactive oxygen species induce antibiotic tolerance during systemic Staphylococcus aureus infection

(2020) Sarah E. Rowe et al.   Nature Microbiology

Involvement of caspase‐1 in inflammasomes activation and bacterial clearance in S. aureus ‐infected osteoblasts‐like MG ‐63 cells

(2020) Elma Lima Leite et al.   CELLULAR MICROBIOLOGY

Host nutrient milieu drives an essential role for aspartate biosynthesis during invasive Staphylococcus aureus infection

(2020) Aimee D. Potter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pulmonary Pathogens Adapt to Immune Signaling Metabolites in the Airway

(2020) Sebastián A. Riquelme et al.   Frontiers in Immunology

Staphylococcus Agr virulence is critical for epidermal colonization and associates with atopic dermatitis development

(2020) Yuumi Nakamura et al.   Science Translational Medicine

Genotypic and Phenotypic Diversity of Staphylococcus aureus Isolates from Cystic Fibrosis Patient Lung Infections and Their Interactions with Pseudomonas aeruginosa

(2020) Eryn E. Bernardy et al.   mBio

Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection

(2020) Cortney E. Heim et al.   Nature Microbiology

Metabolic cross-talk between human bronchial epithelial cells and internalized Staphylococcus aureus as a driver for infection

(2019) Laura M. Palma Medina et al.   MOLECULAR & CELLULAR PROTEOMICS

Chronic Staphylococcus aureus Lung Infection Correlates With Proteogenomic and Metabolic Adaptations Leading to an Increased Intracellular Persistence

(2019) Xin Tan et al.   CLINICAL INFECTIOUS DISEASES

Metabolic Adaptation in MRSA Pneumonia

(2019) Stanislaw J. Gabryszewski et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation

(2019) Nathan Kelley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Staphylococcus aureus small colony variants impair host immunity by activating host cell glycolysis and inducing necroptosis

(2019) Tania Wong Fok Lung et al.   Nature Microbiology

Prevalence and clinical associations of Staphylococcus aureus small-colony variant respiratory infection in children with cystic fibrosis (SCVSA): a multicentre, observational study

(2019) Daniel J Wolter et al.   Lancet Respiratory Medicine

Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity

(2018) Michael D. Kornberg et al.   SCIENCE

Staphylococcus aureus and Atopic Dermatitis: A Complex and Evolving Relationship

(2018) Joan A. Geoghegan et al.   TRENDS IN MICROBIOLOGY

Mutation of Agr Is Associated with the Adaptation of Staphylococcus aureus to the Host during Chronic Osteomyelitis

(2018) Carlos M. Suligoy et al.   Frontiers in Cellular and Infection Microbiology

Genome Plasticity of agr-Defective Staphylococcus aureus during Clinical Infection

(2018) Deena R. Altman et al.   INFECTION AND IMMUNITY

Metabolic Stress Drives Keratinocyte Defenses against Staphylococcus aureus Infection

(2017) Matthew Wickersham et al.   Cell Reports

Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity

(2016) Rob J.W. Arts et al.   Cell Metabolism

Clinical Significance and Pathogenesis of Staphylococcal Small Colony Variants in Persistent Infections

(2016) Barbara C. Kahl et al.   CLINICAL MICROBIOLOGY REVIEWS

Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling

(2016) Kipyegon Kitur et al.   Cell Reports

Neutrophil-generated oxidative stress and protein damage inStaphylococcus aureus

(2016) William N. Beavers et al.   Pathogens and Disease

Metabolic reprogramming in macrophages and dendritic cells in innate immunity

(2015) Beth Kelly et al.   CELL RESEARCH

Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia

(2015) Norberto González-Juarbe et al.   PLoS Pathogens

Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular

(2015) Jason H. Melehani et al.   PLoS Pathogens

Toxin-Induced Necroptosis Is a Major Mechanism of Staphylococcus aureus Lung Damage

(2015) Kipyegon Kitur et al.   PLoS Pathogens

Quorum-sensing regulation in staphylococci—an overview

(2015) Katherine Y. Le et al.   Frontiers in Microbiology

High-Resolution Transcriptomic Analysis of the Adaptive Response of Staphylococcus aureus during Acute and Chronic Phases of Osteomyelitis

(2014) Anna K. Szafranska et al.   mBio

Staphylococcus aureus small colony variants show common metabolic features in central metabolism irrespective of the underlying auxotrophism

(2014) André Kriegeskorte et al.   Frontiers in Cellular and Infection Microbiology

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

NLRP3 inflammasome activation: CD36 serves double duty

(2013) Jonathan C Kagan et al.   NATURE IMMUNOLOGY

Role of Protein A in the Evasion of Host Adaptive Immune Responses by Staphylococcus aureus

(2013) F. Falugi et al.   mBio

Staphylococcus aureus Activation of Caspase 1/Calpain Signaling Mediates Invasion Through Human Keratinocytes

(2012) Grace Soong et al.   JOURNAL OF INFECTIOUS DISEASES

Nasal Carriage as a Source of agr-Defective Staphylococcus aureus Bacteremia

(2012) Davida S. Smyth et al.   JOURNAL OF INFECTIOUS DISEASES

Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome

(2012) Dirk Holzinger et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Staphylococcus aureus Evades Lysozyme-Based Peptidoglycan Digestion that Links Phagocytosis, Inflammasome Activation, and IL-1β Secretion

(2010) Takahiro Shimada et al.   Cell Host & Microbe

A Critical Role for Hemolysins and Bacterial Lipoproteins in Staphylococcus aureus-Induced Activation of the Nlrp3 Inflammasome

(2009) R. Munoz-Planillo et al.   JOURNAL OF IMMUNOLOGY

Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells

(2009) Robin R. Craven et al.   PLoS One